6 results on '"Kusche, Daniel"'
Search Results
2. Milk processing increases the allergenicity of cow's milk-Preclinical evidence supported by a human proof-of-concept provocation pilot
- Author
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Abbring, Suzanne, Kusche, Daniel, Roos, Thomas C, Diks, Mara A P, Hols, Gert, Garssen, Johan, Baars, Ton, van Esch, Betty C A M, Afd Pharmacology, and Pharmacology
- Subjects
0301 basic medicine ,Whey protein ,Food Handling ,mouse model ,Immunology ,Provocation test ,Basic Mechanisms in Allergic Disease ,Milk allergy ,Pilot Projects ,Immunoglobulin E ,Proof of Concept Study ,03 medical and health sciences ,Mice ,0302 clinical medicine ,fluids and secretions ,Food allergy ,milk processing ,cow's milk allergic children ,medicine ,Immunology and Allergy ,Animals ,Humans ,Food science ,Dairy cattle ,biology ,Milk protein ,business.industry ,food and beverages ,Vorzugsmilch ,Raw milk ,oral provocation pilot ,medicine.disease ,cow's milk ,030104 developmental biology ,Milk ,Whey Proteins ,030228 respiratory system ,allergenicity ,vorzugmilch ,Acute Disease ,biology.protein ,Cattle ,Female ,Original Article ,Milk Hypersensitivity ,ORIGINAL ARTICLES ,business - Abstract
Background Several studies demonstrated the adverse effect of milk processing on the allergy‐protective capacity of raw cow's milk. Whether milk processing also affects the allergenicity of raw milk is hardly investigated. Objective To assess the allergenicity of raw (unprocessed) and processed cow's milk in a murine model for food allergy as well as in cow's milk allergic children. Methods C3H/HeOuJ mice were either sensitized to whole milk (raw cow's milk, heated raw cow's milk or shop milk [store‐bought milk]) and challenged with cow's milk protein or they were sensitized and challenged to whey proteins (native or heated). Acute allergic symptoms, mast cell degranulation, allergen‐specific IgE levels and cytokine concentrations were determined upon challenge. Cow's milk allergic children were tested in an oral provocation pilot with organic raw and conventional shop milk. Results Mice sensitized to raw milk showed fewer acute allergic symptoms upon intradermal challenge than mice sensitized to processed milk. The acute allergic skin response was low (103 ± 8.5 µm vs 195 ± 17.7 µm for heated raw milk, P
- Published
- 2019
3. Fatty acid profiles and antioxidants of organic and conventional milk from low- and high-input systems during outdoor period.
- Author
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Kusche, Daniel, Kuhnt, Katrin, Ruebesam, Karin, Rohrer, Carsten, Nierop, Andreas FM, Jahreis, Gerhard, and Baars, Ton
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FATTY acid analysis , *ANTIOXIDANT analysis , *MILK quality , *ORGANIC dairy farming , *DAIRY products - Abstract
BACKGROUND: Intensification of organic dairy production leads to the question of whether the implementation of intensive feeding incorporating maize silage and concentrates is altering milk quality. Therefore the fatty acid (FA) and antioxidant (AO) profiles of milk on 24 farms divided into four system groups in three replications (n=71) during the outdoor period were analyzed. In this system comparison, a differentiation of the system groups and the effects of the main system factors 'intensification level' (high-input versus low-input) and 'origin' (organic versus conventional) were evaluated in a multivariate statistical approach. RESULTS: Consistent differentiation of milk from the system groups due to feeding-related impacts was possible in general and on the basis of 15 markers. The prediction of the main system factors was based on four or five markers. The prediction of 'intensification level' was based mainly on CLA c9, t11 and C18:1 t11, whereas that of 'origin' was based on n-3 PUFA. CONCLUSION: It was possible to demonstrate consistent differences in the FA and AO profiles of organic and standard conventional milk samples. Highest concentrations of nutritionally beneficial compounds were found in the low-input organic system. Adapted grass-based feeding strategies including pasture offer the potential to produce a distinguishable organicmilk product quality. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
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4. Experimental improvement of cow milk fatty acid composition in organic winter diets.
- Author
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Baars, Ton, Wohlers, Jenifer, Kusche, Daniel, and Jahreis, Gerhard
- Abstract
BACKGROUND: Organic milk is seen as more healthy in terms of its fatty acid (FA) profile. In three on-farm crossover trials with 10-12 cows in each group, different forages were compared for their potential to improve the FA composition. Different hay qualities (hay of pasture vs. hay of leys), additional energy sources (fodder beets vs. wheat) and roughage qualities (hay of pasture vs. grass silage) were compared for their effect on the FA composition of the milk. RESULTS: Rumenic acid (CLA cis-9, trans-11) and α-linolenic acid (ALA) were selected as principal markers to evaluate effects. The overall CLA cis-9, trans-11 was low (3.6-6.3 g kg
−1 fat), whereas ALA levels were intermediate (6.8-9.4 g kg−1 fat). Differences between the forages were explained by the fat metabolism of the ruminants. CONCLUSION: Organic winter milk is low in several desirable FAs. Diets rich in mature fodder and sugar were a poor choice for an improved FA composition. Copyright © 2011 Society of Chemical Industry [ABSTRACT FROM AUTHOR]- Published
- 2012
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5. Organic food quality: a framework for concept, definition and evaluation from the European perspective.
- Author
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Kahl, Johannes, Baars, Ton, Bügel, Susanne, Busscher, Nicolaas, Huber, Machteld, Kusche, Daniel, Rembiałkowska, Ewa, Schmid, Otto, Seidel, Kathrin, Taupier-Letage, Bruno, Velimirov, Alberta, and Załȩcka, Aneta
- Abstract
Consumers buy organic food because they believe in the high quality of the product. Furthermore, the EU legal regulatory framework for organic food and farming defines high quality of the products as an important goal of production. A major challenge is the need to define food quality concepts and methods for determination. A background is described which allows embedding of the quality definitions as well as evaluation methods into a conceptual framework connected to the vision and mission of organic agriculture and food production. Organic food quality is defined through specific aspects and criteria. For evaluation each criterion has to be described by indicators. The determination of indicators should be through parameters, where parameters are described by methods. Conversely, the conceptual framework is described according to underlying principles and starting definitions are given, but further work has do be done on the detailed scientific description of the indicators. Furthermore, parameters have to be defined for the evaluation of suitability of these indicators for organic food production. Copyright © 2012 Society of Chemical Industry [ABSTRACT FROM AUTHOR]
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- 2012
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6. The Concept of 'Structure' in the Evaluation of Food Quality.
- Author
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Kusche, Daniel, Busscher, Nicolaas, Kahl, Johannes, and Ploeger, Angelika
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FOOD quality ,PRODUCT quality ,AGRICULTURAL processing ,AGRICULTURAL productivity ,FOOD industry ,AGRICULTURE - Abstract
The concept of structure and the term 'structure' are widely used in manifold applications and disciplines in the conventional and organic sector of food research. This literature survey focuses on the tension charged field of food quality. After the identification of very differing meanings and contrasting attributes of the concept of structure in the two traditions, the usage and interpretation of the term were examined and explained against the background of underlying paradigms and in the context of application. Processes in the agricultural production and food processing were among others directed and controlled on the basis of different interpretations of the term 'structure'. This could have severe consequences for the quality and safety of food. In the organic tradition the concepts of wholefood nutrition which are referring to the term 'structure' are not accomplished but seem to uphold core aspects of food quality and safety which have been lost in current mainstream concepts. Structure has to be brought into relation to health related aspects of food quality. Basic concepts of the organic movement like the whole food nutrition already practise methods which integrated structural aspects of food quality. [ABSTRACT FROM AUTHOR]
- Published
- 2010
- Full Text
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