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7 results on '"Kubíčková, Pavla"'

3. Hybridization Approach Toward Novel Antituberculars: Design, Synthesis, and Biological Evaluation of Compounds Combining Pyrazinamide and 4‑Aminosalicylic Acid.

Author

Bouz, Ghada, Šlechta, Petr, Jand'ourek, Ondřej, Konečná, Klára, Paterová, Pavla, Bárta, Pavel, Novák, Martin, Kučera, Radim, Dal, Nils-Jørgen Knudsen, Fenaroli, Federico, Zemanová, Júlia, Forbak, Martin, Korduláková, Jana, Pavliš, Oto, Kubíčková, Pavla, Doležal, Martin, and Zitko, Jan

Published
2023
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4. Retrospective Analysis Revealed an April Occurrence of Monkeypox in the Czech Republic.

Author

Chmel, Martin, Bartoš, Oldřich, Kabíčková, Hana, Pajer, Petr, Kubíčková, Pavla, Novotná, Iva, Bartovská, Zofia, Zlámal, Milan, Burantová, Anna, Holub, Michal, Jiřincová, Helena, Nagy, Alexander, Černíková, Lenka, Zákoucká, Hana, and Dresler, Jiří

Subjects
MONKEYPOX, RETROSPECTIVE studies, DATA analysis
Abstract

Herein, we present our findings of an early appearance of the Monkeypox virus in Prague, Czech Republic. A retrospective analysis of biological samples, carried out on the 28th of April, revealed a previously unrecognized case of Monkeypox virus (MPxV) infection. Subsequent data analysis confirmed that the virus strain belongs to the ongoing outbreak. Combined with clinical and epidemiological investigations, we extended the roots of the current outbreak at least back to 16th of April, 2022. [ABSTRACT FROM AUTHOR]

Published
2022
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7. Acute Pneumonia Caused by Clinically Isolated Legionella pneumophila Sg 1, ST 62: Host Responses and Pathologies in Mice.

Author

Trousil, Jiří, Frgelecová, Lucia, Kubíčková, Pavla, Řeháková, Kristína, Drašar, Vladimír, Matějková, Jana, Štěpánek, Petr, and Pavliš, Oto

Subjects
LEGIONNAIRES' disease, LEGIONELLA pneumophila, PNEUMONIA, LUNG infections, PATHOLOGY
Abstract

Legionnaires' disease is a severe form of lung infection caused by bacteria belonging to the genus Legionella. The disease severity depends on both host immunity and L. pneumophila virulence. The objective of this study was to describe the pathological spectrum of acute pneumonia caused by a virulent clinical isolate of L. pneumophila serogroup 1, sequence type 62. In A/JOlaHsd mice, we compared two infectious doses, namely, 104 and 106 CFU, and their impact on the mouse status, bacterial clearance, lung pathology, and blood count parameters was studied. Acute pneumonia resembling Legionnaires' disease has been described in detail. [ABSTRACT FROM AUTHOR]

Published
2022
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