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Reproductive tract infections have long been hypothesized to be risk factors for development of uterine fibroids, but few studies have investigated the issue. In our 2016 cross-sectional analysis from the Study of Environment, Lifestyle and Fibroids (2010–2018), a large Detroit, Michigan, community-based cohort study of 23- to 35-year-old African-American women with ultrasound fibroid screening, we found no association between a very prevalent reproductive tract infection, herpes simplex virus type 2 (HSV-2), and fibroids. With prospective data from the cohort (ultrasounds performed every 20 months over 5 years), we examined HSV-2’s associations with fibroid incidence (among 1,208 women who were fibroid-free at baseline) and growth (among women with fibroids at baseline or diagnosed during the study). Using Cox proportional hazards models, we computed adjusted hazard ratios and 95% confidence intervals for fibroid incidence comparing HSV-2–seropositive women with HSV-2–seronegative women. The influence of HSV-2 infection on growth was assessed on the basis of the difference in fibroid size between successive ultrasounds (1,323 growth measures) using a linear mixed model, estimating the percent difference in growth scaled to 18 months. HSV-2 seropositivity was not associated with fibroid incidence (adjusted hazard ratio = 0.88, 95% confidence interval: 0.69, 1.12) or growth (estimated growth difference = 3.1%, 95% confidence interval: −5.8, 13.0). Women can be reassured that HSV-2 infection is unlikely to increase their risk of fibroid-related health problems, given these longitudinal measures.

Background: Bacterial vaginosis (BV), the leading cause of vaginal discharge, is associated with multiple adverse health outcomes; however, its etiology is unknown. BV treatment is not very effective, thus prevention approaches are needed. Studies investigating the impact of vitamin D on the risk of BV have had mixed findings, including two studies reporting increased risk of recurrent BV for women with higher vitamin D. Materials and Methods: Participants were nonpregnant women in a prospective fibroid study of African Americans (ages 23–34 years) from the Detroit area. The exposure was seasonally adjusted annual mean serum 25-hydroxyvitamin D [25(OH)D] at enrollment. The outcome was self-reported doctor-diagnosed BV over ∼20 months between baseline and follow-up. Multivariable-adjusted binomial regression models estimated the risk of BV for a doubling of 25(OH)D and sufficient (≥20 ng/mL) versus deficient (

Background : Environmental impact studies often enlist professional communicators to develop and implement public engagement plans and processes. However, few detailed reports of these public engagement plans exist in either scholarly venues or government reports. This case reviews one public engagement project in transportation planning as implemented by one professional communications firm. Research questions: 1) What communication and engagement strategies do the consultants employ in their public engagement process? 2) How do professional communicators design engagement for diverse citizen groups? Situating the case: A number of cases have revealed the ways professional and technical communicators integrate participatory or user-centered design strategies in public engagement projects. These cases suggest that professional and technical communicators are uniquely positioned to develop ethical and effective public engagement plans for environmental impact studies. Professional and technical communicators are further prepared for this work because of their knowledge about theories of intercultural communication and rhetorical theories of delivery. Methodology: This case was studied over the course of 1.5 years using qualitative research methods, including observations, interviews, and textual analysis. About the case: This case reviews the work of one particular public engagement firm, VTC Communications, as they planned and implemented public engagement in one environmental impact study. This environmental impact study team was tasked with determining the best way to accommodate the increase in rail traffic the city anticipated with the development of the high-speed rail. The public's input was needed to fulfill environmental impact statement (EIS) requirements and to fully understand the community concerns regarding the increased traffic, noise, vibrations, and family/business displacements. VTC Communications was hired to conduct this portion of the environmental impact study, and their work included the development of a range of deliverables and events. Conclusions: This case provides an overview of the process of developing public engagement plans, the deliverables designed, as well as the key goals that guided the development of public engagement. My case suggests that effective public engagement can address intercultural concerns by developing projects that are adaptable, multimodal, and dialogic.

For decades reproductive tract infections (RTIs) have been hypothesized to play a role in uterine fibroid development. The few previous studies conducted used self-reported history of RTIs and had inconsistent findings. We investigated this hypothesis further using serological analysis, an immunological measure of past exposure. We focused on herpes simplex virus type 2 (HSV-2) because prior published data have suggested a possible association with fibroids, and serology for HSV-2 is much more sensitive than self-report. We used cross-sectional enrollment data from African-American women enrolled in a prospective study of fibroid incidence and growth (recruited 2010–2012) in the Detroit, Michigan, area. The women were aged 23–34 years and were screened for fibroids using a standardized ultrasound examination at their enrollment. Age- and multivariable-adjusted logistic regression models were used to estimate odds ratios. Of 1,696 participants, 1,658 had blood samples and HSV-2 serology results; 22% of participants with serology results had fibroids. There was no significant association between HSV-2 seropositivity and the presence of fibroids (multivariable-adjusted odds ratio = 0.94, 95% confidence interval: 0.73, 1.20), nor were there any associations with size of the largest fibroid, number of fibroids, or total fibroid volume. Our data provide no evidence for an influence of HSV-2 exposure on fibroid risk in young African-American women. Further study of other serologically measured RTIs is warranted.

Uterine fibroids are common, benign, smooth-muscle tumors that can cause major morbidity for reproductive-age women, often requiring invasive treatment. Despite this personal and public health burden, no prior study has attempted to periodically screen fibroid-free women with ultrasound to detect incident disease and identify risk factors.We designed a study to prospectively investigate development of fibroids by enrolling women without a clinical diagnosis of fibroids and screening for fibroids with ultrasound at baseline. Enrollment procedures included extensive questionnaires and specimen collection (blood, urine, vaginal swabs). The cohort is followed at approximately 20-month intervals. At each follow-up there are updates to the questionnaire data, further specimen collection, and an ultrasound examination. We identify incident disease and measure tumor growth. The two exposures of primary interest are vitamin D insufficiency and reproductive tract infections. This manuscript provides a detailed description of the study methods, recruitment results, and participant characteristics.The Study of Environment, Lifestyle and Fibroids enrolled 1,696 African American women aged 23-34 years. "Family and friends" was a leading recruitment source. More than 95% of participants contributed all the requested biological specimens at baseline. Study ultrasound examinations revealed undiagnosed fibroids in 378 women (22% of participants). The retention rate for the first follow-up was 87%.Study design aspects likely to be important for long-term studies in young African Americans include personalized recruitment, multiple steps to the enrollment process that rely on the initiative of the participant, and methods for tracing highly mobile study subjects.

This article brings together the communication needs and positioning of women in technical areas, and asks “how can technical communication classes contribute to the mentoring of young women engineers at a time when many of those women want to be identified as engineers instead of being spotlighted as women in engineering?” Incorporating research into mentoring for women in engineering, and feminist approaches to mentoring in general, we adopt Heath and Heath's strategy in Switch, instituting small changes in technical communication classes (and sometimes their infrastructures) that target a mentoring problem—i.e., talk about time—with the hope of flipping a switch toward larger changes. Thus, the article demonstrates two tactics that we can use to deliver improvement in managing the discourse surrounding time and its deadlines. Our approach both mentors undergraduate women in more actively and effectively discussing and scheduling their work without singling them out as women and also integrates good mentoring practice into the infrastructure of technical communication service classes.

Within a Technical Communication classroom, policywork has been used to teach students the vital discursive and conceptual skills valued by technical fields. However, given the move of technical communicators into the public sphere, these skills can and should be expanded to include diverse practices and modes of thought. As such, this article suggests that storytelling can be used as a pedagogical tool to help students think more critically about the (sometimes hidden) relationships that policywork inheres. This article articulates relational work as a target skills set for students and suggests specific activities and handouts for developing these skills.