348 results on '"Kobe, Bostjan"'
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2. Toll/interleukin-1 receptor domains in bacterial and plant immunity
3. TIR domain-associated nucleotides with functions in plant immunity and beyond
4. Capsaicin receptor TRPV1 maintains quiescence of hepatic stellate cells in the liver via recruitment of SARM1
5. Structural and biochemical characterization of Acinetobacter baumannii ZnuA
6. Megahertz pulse trains enable multi-hit serial femtosecond crystallography experiments at X-ray free electron lasers
7. Exon shuffling and alternative splicing of ROCO genes in brown algae enables a diverse repertoire of candidate immune receptors.
8. The JAK-STAT pathway: from structural biology to cytokine engineering.
9. SARM1-Dependent Axon Degeneration: Nucleotide Signaling, Neurodegenerative Disorders, Toxicity, and Therapeutic Opportunities.
10. Autoimmunity and effector recognition in Arabidopsis thaliana can be uncoupled by mutations in the RRS1-R immune receptor
11. MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography
12. Comprehensive analysis of IncC plasmid conjugation identifies a crucial role for the transcriptional regulator AcaB
13. Molecular basis of regio- and stereo-specificity in biosynthesis of bacterial heterodimeric diketopiperazines
14. Solution structure of the TLR adaptor MAL/TIRAP reveals an intact BB loop and supports MAL Cys91 glutathionylation for signaling
15. Multiple functional self-association interfaces in plant TIR domains
16. Animal NLRs provide structural insights into plant NLR function
17. Structural Basis and Prediction of Substrate Specificity in Protein Serine/Threonine Kinases
18. Crystal Structure of Human T Cell Leukemia Virus Type 1 gp21 Ectodomain Crystallized as a Maltose-Binding Protein Chimera Reveals Structural Evolution of Retroviral Transmembrane Proteins
19. The Myosin-I-Binding Protein Acan125 Binds the SH3 Domain and Belongs to the Superfamily of Leucine-Rich Repeat Proteins
20. Prediction of kinase-specific phosphorylation sites through an integrative model of protein context and sequence
21. The CC domain structure from the wheat stem rust resistance protein Sr33 challenges paradigms for dimerization in plant NLR proteins
22. Comparative Analysis of the Flax Immune Receptors L6 and L7 Suggests an Equilibrium-Based Switch Activation Model
23. Characterizing the conformational dynamics of metal-free PsaA using molecular dynamics simulations and electron paramagnetic resonance spectroscopy
24. Pathological mutations differentially affect the self-assembly and polymerisation of the innate immune system signalling adaptor molecule MyD88
25. A bioinformatics tool for epitope-based vaccine design that accounts for human ethnic diversity: Application to emerging infectious diseases
26. A non-uniform sampling approach enables studies of dilute and unstable proteins
27. Structural Basis for Assembly and Function of a Heterodimeric Plant Immune Receptor
28. A rust‐fungus Nudix hydrolase effector decaps mRNAin vitro and interferes with plant immune pathways.
29. Megahertz serial crystallography
30. Structures of the flax-rust effector AvrM reveal insights into the molecular basis of plant-cell entry and effector-triggered immunity
31. Crystal Structure of Rice Importin-α and Structural Basis of Its Interaction with Plant-Specific Nuclear Localization Signals
32. Discovery of C‑5 Pyrazole-Substituted Pyrrolopyridine Derivatives as Potent and Selective Inhibitors for Janus Kinase 1.
33. Exon shuffling potentiates a diverse repertoire of brown algal NB‐ARC‐TPR candidate immune receptor proteins via alternative splicing.
34. Structure and function of Toll/interleukin-1 receptor/resistance protein (TIR) domains
35. Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection
36. Mildew RALPHs up in arms with cereals.
37. Crystal Structures of Flax Rust Avirulence Proteins AvrL567-A and -D Reveal Details of the Structural Basis for Flax Disease Resistance Specificity
38. Structural Basis for Recruitment of Tandem Hotdog Domains in Acyl-CoA Thioesterase 7 and Its Role in Inflammation
39. Direct Protein Interaction Underlies Gene-For-Gene Specificity and Coevolution of the Flax Resistance Genes and Flax Rust Avirulence Genes
40. Crystal structure of Mycobacterium tuberculosis ketol-acid reductoisomerase at 1.0 Å resolution – a potential target for anti-tuberculosis drug discovery
41. A linker strategy for the production and crystallization of Toll/interleukin-1 receptor/resistance protein domain complexes
42. PhosphoPICK: modelling cellular context to map kinase-substrate phosphorylation events
43. In silico screening of small molecule libraries using the dengue virus envelope E protein has identified compounds with antiviral activity against multiple flaviviruses
44. Engineering indel and substitution variants of diverse and ancient enzymes using Graphical Representation of Ancestral Sequence Predictions (GRASP).
45. Enhancing the Thermal and Kinetic Stability of Ketol-Acid Reductoisomerase, a Central Catalyst of a Cell-Free Enzyme Cascade for the Manufacture of Platform Chemicals.
46. Conserved anchorless surface proteins as group A streptococcal vaccine candidates
47. Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing
48. Structural Basis of Interaction of Bipartite Nuclear Localization Signal from Agrobacterium VirD2 with Rice Importin-α
49. AdcA and AdcAII employ distinct zinc acquisition mechanisms and contribute additively to zinc homeostasis in Streptococcus pneumoniae
50. Identification of novel target sites and an inhibitor of the dengue virus E protein
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