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Aeroelastic divergence analysis of a stable wing structure was performed using a coupled aerodynamic/structural method and validated using wind tunnel tests. To ensure the accuracy of numerical analysis, CFD method was used for aerodynamic force calculation and finite element method was used for structural deformation calculation. The wind tunnel test used a sidewall insertion mechanism for support and measured the static aeroelastic divergence characteristics through strain measurement and high-speed photography. The stable wing model was used as the research object for studying the static aeroelastic divergence characteristics in supersonic state. The results of numerical calculation and wind tunnel test showed that the CFD/CSD coupling method can accurately predict the static aeroelastic divergence boundary. Static aeroelastic divergence presents an explosive form of destruction. The static aeroelastic unstable structure first suffers from elastic loading exceeding the structural strength limit and the damage occurs with the dynamic pressure not reaching the divergence boundary. Accurate prediction of the static aeroelastic divergence boundary of the aircraft is necessary for aircraft structural design.

In dermatology, photodynamic therapy (PDT) has become a well established treatment modality which has been shown to be effective and safe for many skin and mucosal disorders. Pre-clinical and clinical studies demonstrate that, in addition to the direct local cytotoxicity and vascular effects, PDT can induce various host immune responses. Recent clinical data also show that improved clinical outcomes can be obtained through the sequential use of PDT and immunomodulation. This article will provide an update on the current status of such a combination in dermatological applications. [ABSTRACT FROM AUTHOR]

AbstractInfantile hemangiomas are common benign vascular tumors of infancy. Although the majority of uncomplicated hemangiomas involute spontaneously, rapid-growth lesions with complications need early active intervention. On the other hand, severe and complicated lesions can be difficult to treat. Recently, we successfully treated two cases of giant severe infantile facial hemangiomas using local application of bleomycin and pulsed dye laser along with systemic application of dexamethasone. Our results suggest that the multiple modalities of bleomycin, laser, and corticosteroid are a safe and effective approach for early therapeutic intervention of severe facial hemangiomas. [ABSTRACT FROM AUTHOR]