1. Does adenosine deaminase activity play a role in the early diagnosis of ectopic pregnancy?
- Author
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Turkmen, G. G., Karçaaltıncaba, D., Isık, H., Fidancı, V., Kaayalp, D., Tımur, H., and Batıoglu, S.
- Subjects
ADENOSINE deaminase ,ECTOPIC pregnancy ,PREGNANCY complication risk factors ,FETAL heart rate monitoring ,DIAGNOSTIC ultrasonic imaging ,FETAL heart rate ,DIAGNOSIS ,HYDROLASES ,CASE-control method ,EARLY diagnosis - Abstract
Early diagnosis of ectopic pregnancy (EP) is important due to life-threatening consequences in the first trimester of pregnancy. In this study we aimed to investigate the role of adenosine deaminase (ADA) activity in the prediction of EP. Forty-one patients with unruptured ectopic pregnancy comprised the case group and forty-two first trimester pregnant women with shown foetal heart beating in ultrasound comprised the control group. The mean ADA level in EP (10.9 ± 3.0 IU/L) was higher than that in control group (9.2 ± 3.6 IU/L) (p = 0.018). Receiver operating characteristics or ROC curve identified ADA value of 10.95 IU/L as optimal threshold for the prediction of EP with 56% sensitivity and 67% specificity. High ADA levels are valuable in the early diagnosis of EP. However more comprehensive studies are required. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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