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In this report, we describe two cases of basal cell carcinoma (BCC), one of them is on the lower lip and the other is on the popliteal area. A 45-year-old male patient with an unhealed wound on the lower lip and a 38-year-old male patient with an unhealed wound over the popliteal skin were admitted to our clinic. There was no sun exposure and trauma in their medical history. A biopsy was taken from each case. The results were BCC in two patients. BCC is usually seen in the head and neck regions, but it may be also localized in rare areas such as the lower lip and lower extremity. These unpredictable areas should be considered for tumor surgery.