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41 results on '"Jostins, Luke"'

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1. HLA-DP on Epithelial Cells Enables Tissue Damage by NKp44+ Natural Killer Cells in Ulcerative Colitis

2. Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19

3. A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

4. An Integrated Taxonomy for Monogenic Inflammatory Bowel Disease

6. Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders

11. Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

12. Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7

15. Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations

16. A Systematic Survey of Loss-of-Function Variants in Human Protein-Coding Genes

17. A global reference for human genetic variation

18. Negligible impact of rare autoimmune-locus coding-region variants on missing heritability

19. An integrated map of genetic variation from 1,092 human genomes

20. Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

21. A Systematic Survey of Loss-of-Function Variants in Human Protein-Coding Genes

23. A map of human genome variation from population-scale sequencing

26. Active immunisation targeting nerve growth factor attenuates chronic pain behaviour in murine osteoarthritis.

27. Fine-mapping inflammatory bowel disease loci to single-variant resolution.

28. Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity.

29. Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.

30. High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis.

31. Using Genetic Prediction from Known Complex Disease Loci to Guide the Design of Next-Generation Sequencing Experiments.

32. Imputation-Based Meta-Analysis of Severe Malaria in Three African Populations

34. Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis.

35. Imputation of low-frequency variants using the HapMap3 benefits from large, diverse reference sets.

36. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.

37. Reverse engineering a gene network using an asynchronous parallel evolution strategy.

38. Trinculo: Bayesian and frequentist multinomial logistic regression for genome-wide association studies of multi-category phenotypes.

39. Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci

40. High density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

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