1. Primary anorectal mucosal melanoma detected by anorectal cytology
- Author
-
D O Melissa Yee-Chang, C T Jolene Octavius, D O Jeanine Chiaffarano, Omar Azar, Ryan Paul Lau, Yan Shi, and Melissa Alexander
- Subjects
Pathology ,medicine.medical_specialty ,Histology ,business.industry ,Melanoma ,Mucosal melanoma ,General Medicine ,Anal canal ,medicine.disease ,Pathology and Forensic Medicine ,Anal cytology ,03 medical and health sciences ,0302 clinical medicine ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,Cytology ,MART-1 Antigen ,medicine ,Immunohistochemistry ,030212 general & internal medicine ,business ,Anal Melanoma - Abstract
The detection of primary anorectal melanoma on anal cytology is a rare and challenging diagnosis. We report a case where anorectal cytology showed isolated malignant cells with oval nuclei, prominent nucleoli, and elongated wispy cytoplasmic projections. There was no evidence of squamous dysplasia or melanin pigment identified. To the best of our knowledge, this is the first reported case of a primary anorectal melanoma detected in anorectal cytology. Detection of malignancies other than squamous cell carcinoma can be seen on anorectal cytology and should be considered when there is no evidence of anal intraepithelial neoplasia. Diagn. Cytopathol. 2017;45:452-455. © 2017 Wiley Periodicals, Inc.
- Published
- 2017
- Full Text
- View/download PDF