294 results on '"Hirano, Toshio"'
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2. Pleiotropy and Specificity: Insights from the Interleukin 6 Family of Cytokines
3. FcεRI-Mediated Mast Cell Degranulation Requires Calcium-Independent Microtubule-Dependent Translocation of Granules to the Plasma Membrane
4. STAT3 Noncell-Autonomously Controls Planar Cell Polarity during Zebrafish Convergence and Extension
5. Gab1 and SHP-2 Promote Ras/MAPK Regulation of Epidermal Growth and Differentiation
6. Asymmetric p38 Activation in Zebrafish: Its Possible Role in Symmetric and Synchronous Cleavage
7. Mast cells play role in wound healing through the ZnT2/GPR39/IL-6 axis
8. Zinc-binding metallothioneins are key modulators of IL-4 production by basophils
9. Disease-Association Analysis of an Inflammation-Related Feedback Loop
10. Regional Neural Activation Defines a Gateway for Autoreactive T Cells to Cross the Blood-Brain Barrier
11. Biochemical Characterization of Human ZIP13 Protein: A HOMO-DIMERIZED ZINC TRANSPORTER INVOLVED IN THE SPONDYLOCHEIRO DYSPLASTIC EHLERS-DANLOS SYNDROME
12. Zinc Is a Novel Intracellular Second Messenger
13. SHP2 mediates gp130-dependent cardiomyocyte hypertrophy via negative regulation of skeletal alpha-actin gene
14. Hepatic Interleukin-7 Expression Regulates T Cell Responses
15. Cloning and Expression of the Human Interleukin-6 (BSF-2/IFN$\beta $ 2) Receptor
16. Human B-Cell Differentiation Factor Defined by an Anti-Peptide Antibody and Its Possible Role in Autoantibody Production
17. BST-1, a Surface Molecule of Bone Marrow Stromal Cell Lines that Facilitates pre-B-cell Growth
18. Purification to Homogeneity and Characterization of Human B-Cell Differentiation Factor (BCDF or BSFp-2)
19. AIDS Kaposi Sarcoma-Derived Cells Produce and Respond to Interleukin 6
20. Interleukin 2-Dependent and Interleukin 2-Independent Pathways of Regulation of Thymocyte Function by Interleukin 6
21. IgG1 Plasmacytosis in Interleukin 6 Transgenic Mice
22. Interleukin 6 Induces Secretion of IgG1 by Coordinated Transcriptional Activation and Differential mRNA Accumulation
23. Generation of Plasmacytomas with the Chromosomal Translocation t(12;15) in Interleukin 6 Transgenic Mice
24. Interaction of Scaffolding Adaptor Protein Gab1 with Tyrosine Phosphatase SHP2 Negatively Regulates IGF-I-dependent Myogenic Differentiation via the ERK1/2 Signaling Pathway
25. Interleukin-17 Promotes Autoimmunity by Triggering a Positive-Feedback Loop via Interleukin-6 Induction
26. Roles of Zinc and Zinc Signaling in Immunity: Zinc as an Intracellular Signaling Molecule
27. COVID-19: A New Virus, but a Familiar Receptor and Cytokine Release Syndrome
28. TRIF–GEFH1–RhoB pathway is involved in MHCII expression on dendritic cells that is critical for CD4 T‐cell activation
29. SHP2-mediated signaling cascade through gp130 is essential for LIF-dependent ICaL, [Ca 2+] i transient, and APD increase in cardiomyocytes
30. Gab1 is required for EGF receptor signaling and the transformation by activated ErbB2
31. The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance
32. IL-6 amplifier activation in epithelial regions of bronchi after allogeneic lung transplantation
33. The YXXQ motif in gp 130 is crucial for STAT3 phosphorylation at Ser727 through an H7-sensitive kinase pathway
34. Grasp a pTyr-Peptide by Its SOCS
35. Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors
36. Interleukin-6 and oncostatin M-induced growth inhibition of human A375 melanoma cells is STAT-dependent and involves upregulation of the cyclin-dependent kinase inhibitor p27/Kip1
37. Zinc suppresses Th17 development via inhibition of STAT3 activation
38. IL-6 positively regulates Foxp3+CD8+ T cells in vivo
39. STAT3 orchestrates contradictory signals in cytokine‐induced G1 to S cell‐cycle transition
40. Activation of state3 by v-Src is through a ras-independent pathway
41. IL-6-STAT3 Controls Intracellular MHC Class II αβ Dimer Level through Cathepsin S Activity in Dendritic Cells
42. IFN-γ expression in CD8+ T cells regulated by IL-6 signal is involved in superantigen-mediated CD4+ T cell death
43. Extracellular signal‐dependent nuclear import of Stat1 is mediated by nuclear pore‐targeting complex formation with NPI‐1, but not Rch1
44. Dual control of neurite outgrowth by STAT3 and MAP kinase in PC12 cells stimulated with interleukin‐6
45. Tec tyrosine kinase links the cytokine receptors to PI-3 kinase probably through JAK
46. An alternative pathway for STAT activation that is mediated by the direct interaction between JAK and STAT
47. Intracellular zinc homeostasis and zinc signaling
48. Combination treatment with IL-2 and anti-IL-2 mAbs reduces tumor metastasis via NK cell activation
49. Gab family proteins are essential for postnatal maintenance of cardiac function via neuregulin-1/ErbB signaling
50. IL-6–gp130–STAT3 in T cells directs the development of IL-17+ Th with a minimum effect on that of Treg in the steady state
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