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397 results on '"Heiss, Wolf-Dieter"'

5. From the Left to the Right: How the Brain Compensates Progressive Loss of Language Function

Author

Thiel, Alexander, Habedank, Birgit, Herholz, Karl, Kessler, Josef, Winhuisen, Lutz, Haupt, Walter F., and Heiss, Wolf-Dieter

Abstract

In normal right-handed subjects language production usually is a function of the left brain hemisphere. Patients with aphasia following brain damage to the left hemisphere have a considerable potential to compensate for the loss of this function. Sometimes, but not always, areas of the right hemisphere which are homologous to language areas of the left hemisphere in normal subjects are successfully employed for compensation but this integration process may need time to develop. We investigated right-handed patients with left hemisphere brain tumors as a model of continuously progressive brain damage to left hemisphere language areas using functional neuroimaging and transcranial magnetic stimulation (TMS) to identify factors which determine successful compensation of lost language function. Only patients with slowly progressing brain lesions recovered right-sided language function as detected by TMS. In patients with rapidly progressive lesions no right-sided language function was found and language performance was linearly correlated with the lateralization of language related brain activation to the left hemisphere. It can thus be concluded that time is the factor which determines successful integration of the right hemisphere into the language network for compensation of lost left hemisphere language function.

Published
2006
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20. Clopidogrel Plus Aspirin Versus Warfarin in Patients With Stroke and Aortic Arch Plaques

Author

Amarenco, Pierre, Davis, Stephen, Jones, Elizabeth F., Cohen, Ariel A., Heiss, Wolf-Dieter, Kaste, Markku, Laouénan, Cédric, Young, Dennis, Macleod, Malcolm, Donnan, Geoffrey A., Bladin, Christopher F., Chambers, Brian R., Frayne, Judith, Hankey, Graeme J., Levi, Christopher R., Read, Stephen J., Ravaud, Philippe, Tatlisumak, Turgut, Soinne, Lauri, Laine, Mika, Syvänne, Mikko, Vikatmaa, Pirkka, Lepäntalo, Mauri, Mentré, France, Gosset, Simon, Churilov, Leonid, De Broucker, Thomas, Favrole, Pascal, Mawet, Jérôme, Mocquard, Yves, Obadia, Michael, Godefroy, Olivier, Hosseini, Hassan, Pico, Fernando, Garnier, Pierre, Malbec, Marcel, Pinel, Jean-François, Ille, Olivier, Vadamme, Xavier, Macian-Montoro, Francisco, Servan, Jérôme, Viallet, François, Rosolacci, Thierry, Lecoz, Patrick, Clavelou, Pierre, Detante, Olivier, Cho, Tae-Hee, Saudeau, Denis, Michel, Patrik, D’Ombrogio, Suzette, Serisier, David, Sturm, Jonathon, Kimber, Thomas, Marcus, Romesh, Schwartz, Ray, Helme, Rob, Blacker, David, and Wood, Jonathan

Published
2014
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30. Differential Effects of Speech and Language Therapy and rTMS in Chronic Versus Subacute Post-stroke Aphasia: Results of the NORTHSTAR-CA Trial.

Author

Zumbansen, Anna, Kneifel, Heike, Lazzouni, Latifa, Ophey, Anja, Black, Sandra E., Chen, Joyce L., Edwards, Dylan, Funck, Thomas, Hartmann, Alexander Erich, Heiss, Wolf-Dieter, Hildesheim, Franziska, Lanthier, Sylvain, Lespérance, Paul, Mochizuki, George, Paquette, Caroline, Rochon, Elizabet, Rubi-Fessen, Ilona, Valles, Jennie, Wortman-Jutt, Susan, and Thiel, Alexander

Published
2022
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32. Development of a daily quality check procedure for the high-resolution research tomograph (HRRT) using natural LSO background radioactivity

Author

Knoess, Christof, Gremillion, Tim, Schmand, Matthias, Casey, Mike E., Eriksson, Lars, Lenox, Mark, Treffert, Jon T., Vollmar, Stefan, Fluegge, Guenter, Wienhard, Klaus, Heiss, Wolf-Dieter, and Nutt, Ron

Subjects
Nuclear physics -- Research, PET imaging -- Usage, Diagnostic imaging -- Analysis, Diagnostic imaging -- Methods, Silicates, Radioactivity, Business, Electronics, Electronics and electrical industries
Abstract

A daily quality check (DQC) plays an important role for clinical medical systems like a positron emission tomograph (PET). To guarantee image quality a constant monitoring of the scanner integrity is essential. On present PET scanners, the built-in transmission sources are being used for the measurement of a uniform blank scan and the computation of detector-block efficiencies. These efficiencies can be compared to reference data and deviations indicate changes of the scanner condition. On the high-resolution research tomograph (ECAT HRRT) the design of the transmission source makes this method impractical. For that reason we investigated the use of the natural background radioactivity from the new scintillator material LSO as a uniform source. A procedure was developed to measure detector-block sensitivities and energy spectra directly. An initial quality check (QC) scan is the basis for comparison of daily scans, so that gain shifts of photomultipliers and specific hardware defects can be detected. With an improved list mode based data acquisition it was possible to reduce the acquisition time to around 3 h despite the low LSO count rate, so that this routine is as practical as previous procedures in clinical routine. Index Terms--Daily quality check (DQC), lutetium-oxy-orthosilicate (LSO), positron emission tomography (PET).

Published
2002

50. Stroke: Working toward a Prioritized World Agenda

Author

Hachinski, Vladimir, Donnan, Geoffrey A., Gorelick, Philip B., Hacke, Werner, Cramer, Steven C., Kaste, Markku, Fisher, Marc, Brainin, Michael, Buchan, Alastair M., Lo, Eng H., Skolnick, Brett E., Furie, Karen L., Hankey, Graeme J., Kivipelto, Miia, Morris, John, Rothwell, Peter M., Sacco, Ralph L., Smith, Sidney C., Jr., Wang, Yulun, Bryer, Alan, Ford, Gary A., Iadecola, Costantino, Martins, Sheila C.O., Saver, Jeff, Skvortsova, Veronika, Bayley, Mark, Bednar, Martin M., Duncan, Pamela, Enney, Lori, Finklestein, Seth, Jones, Theresa A., Kalra, Lalit, Kleim, Jeff, Nitkin, Ralph, Teasell, Robert, Weiller, Cornelius, Desai, Bhupat, Goldberg, Mark P., Heiss, Wolf-Dieter, Saarelma, Osmo, Schwamm, Lee H., Shinohara, Yukito, Trivedi, Bhargava, Wahlgren, Nils, Wong, Lawrence K., Hakim, Antoine, Norrving, Bo, Prudhomme, Stephen, Bornstein, Natan M., Davis, Stephen M., Goldstein, Larry B., Leys, Didier, and Tuomilehto, Jaakko

Published
2010
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