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The slow growth rate of empurau (Tor tambroides) fish has been reported, impeding its aquaculture practice extensively in Malaysia. It mainly occurs at the fry to fingerling phase. Hence, the present research evaluated the dietary lacto-sacc feed supplement on the growth performance and health status of T. tambroides fries. The fish growth was outperformed significantly (P < 0.05) after 12 weeks in fish fed with the lacto-sacc supplemented fish feed compared to the nonsupplemented control diet. As with the growth performance, the basic hematological parameters were significantly (P < 0.05) improved. This study was the first attempt to indicate the suitability of dietary lacto-sacc for empurau fries nursery in an aquaponics system. Although this study was performed in four types of aquaponics systems, the factorial analysis confirmed that diet had a strong effect for this occurrence. [ABSTRACT FROM AUTHOR]