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Background: Motor dysfunction profoundly affects individuals with Parkinson's disease (PD). Non-invasive brain stimulation (NIBS) targeting the supplementary motor area (SMA), a critical region for movement-related processing, offers a promising approach to enhance motor function for PD. Objective: This systematic review and meta-analysis aims to evaluate the efficacy of NIBS over the SMA (SMA-NIBS) in alleviating motor symptoms in PD. Methods: We conducted literature searches in MEDLINE, EMBASE, Physiotherapy Evidence Database, Web of Science, the Chinese National Knowledge Infrastructure, and Scopus. The meta-analysis utilized an inverse variance method and a random-effects model. Subgroup analyses were performed based on stimulation types (e.g., TMS and tDCS), stimulation protocols (e.g., facilitatory and inhibitory stimulation), and medication status during stimulation. Results: Twenty randomized control trials involving 442 individuals with PD were included. Compared to sham stimulation, SMA-NIBS significantly improved motor function as measured by the motor section of Unified Parkinson's Disease Rating Scale (UPDRS-III) (mean differences [MD]: −3.45, 95 % confidence interval [CI]: −5.65 to −1.26). Subgroup analysis revealed that only TMS (MD: −3.62, 95%CI: −6.15 to −1.08), not tDCS (MD: −2.47, 95 % CI: −5.03 to 0.08), has significant effect on motor function. Both facilitatory (MD: −2.59, 95 % CI: −3.37 to −1.82) and inhibitory stimulation (MD: −4.98, 95 % CI: −9.29 to −0.66) significantly improved the UPDRS-III score. Effectiveness was observed only during ON medication. Statistically significant effects of SMA-NIBS were reported on Freezing of Gait Questionnaire, not timed up and go test and walking speed. Conclusion: SMA-NIBS is a promising approach to enhance motor function in PD.

Introduction Individuals with Parkinson’s disease (PD) often experience initial hesitation, slowness of movements, decreased balance and impaired standing ability, which can significantly impact their independence. Transcranial magnetic stimulation and transcranial direct current stimulation are two widely used and promising non-invasive brain stimulation (NIBS) modalities for treating PD. The supplementary motor area (SMA), associated with motor behaviour and processing, has received increasing attention as a potential stimulation target to alleviate PD-related symptoms. However, the data on NIBS over SMA in PD individuals are inconsistent and has not been synthesised. In this article, we will review the evidence for NIBS over SMA in PD individuals and evaluate its efficacy in improving PD function.Method and analysis Randomised controlled clinical trials comparing the effects of NIBS and sham stimulation on motor function, activities of daily living and participation for people with PD will be included. A detailed computer-aided search of the literature will be performed from inception to February 2023 in the following databases: PubMed, EMBASE, Physiotherapy Evidence Database (PEDro), Web of Science (WOS) and The Chinese National Knowledge Infrastructure (CNKI). Two independent reviewers will screen articles for relevance and methodological validity. The PEDro scale will be used to evaluate the risk of bias of selected studies. Data from included studies will be extracted by two independent reviewers through a customised, preset data extraction sheet.Ethics and dissemination Ethical approval is not required for this systematic review. The study’s findings will be presented at scientific meetings and published in peer-reviewed journals.PROSPERO registration number CRD42023399945.

In order to improve the transient stability of frequency in a small stand-alone microgrid (SSM), this paper takes a SSM composed of a direct-drive permanent magnet synchronous generator (D-PMSG) and a micro gas turbine (MGT) as the background and uses wind turbine generator (WTG) virtual inertia (VI) to participate in the primary (short-term) system frequency regulation. First of all, this paper constructs a grid-connected model composed of a WTG and a MGT, analyzes the WTG virtual inertia frequency regulation mechanism, and explains the principle of proportional-differentiation (PD) virtual inertia control (VIC) and its shortcomings. Secondly, the paper introduces the structure principle of n-order active disturbance rejection control (ADRC) and deduces the design process of second-order ADRC-VIC. Finally, through the simulation and experimental verification, comparing the frequency perturbation of without-VIC, PD-VIC, and ADRC-VIC, it is concluded that PD-VIC and ADRC-VIC both can use the WTG virtual inertia to participate in the primary frequency regulation. The frequency regulation effect of ADRC-VIC is better than PD-VIC, ADRC-VIC can extend the rotor speed recovery time and avoid overshoot, and its frequency fluctuation amplitude and settling time are obviously improved, and ADRC-VIC can effectively avoid the overshoot phenomenon of the MGT output power. [ABSTRACT FROM AUTHOR]

To enable a master-slave control independent microgrid system (MSCIMGS) to supply electricity continuously, the microgrid inverter should perform mode transfer between grid-connected and islanding operations. Transient oscillations should be reduced during transfer to effectively conduct a seamless mode transfer. This study uses a typical MSCIMGS as an example and improves the mode transfer strategy in three aspects: (1) adopts a status-tracking algorithm to improve the switching strategy of the outer loop, (2) uses the voltage magnitude and phase pre-synchronization algorithm to reduce transient shock at the time of grid connection, and (3) applies the hybrid-sensitivity H∞ robust controller instead of the current inner loop to improve the robustness of the controller. Simulations and experiments show that the proposed strategy is more practical than the traditional proportional-derivative control mode transfer and effective in reducing voltage and current oscillations during the transfer period. [ABSTRACT FROM AUTHOR]