153 results on '"Guerreiro, Manuela"'
Search Results
2. Frequency, sociodemographic, and neuropsychological features of patients with subjective cognitive decline diagnosed using different neuropsychological criteria
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Pestana, Pedro Câmara, Cardoso, Sandra, Guerreiro, Manuela, Maroco, João, Jessen, Frank, do Couto, Frederico Simões, and de Mendonça, Alexandre
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- 2024
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3. Stimulating customer participation behaviour and boosting value co-creation in hotels
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Sadighha, Jinous, Pinto, Patrícia, Guerreiro, Manuela, and Campos, Ana Cláudia
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- 2024
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4. Hedonic experiences at heritage attractions: the visitor’s perspective
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Bender, Ana Carolina, Guerreiro, Manuela, Sequeira, Bernardete Dias, and Mendes, Júlio
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- 2022
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5. On the role of internal stakeholders in place branding
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Golestaneh, Homayoun, Guerreiro, Manuela, Pinto, Patrícia, and Mosaddad, Seyed Hashem
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- 2022
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6. roadening tourism experience and destination image: A cross-cultural approach between international and domestic tourists.
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Guerreiro, Manuela, Pinto, Patrícia, Bagheri, Fatemeh, and Matos, Nelson
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Although previous studies deal with tourism experience, destination image and related outcomes, this study innovates by elaborating on a more comprehensive view of the tourism experience and destination image. Guided by suggestions for more research in the relevant literature, this study examines the correlation between tourism experience, experiential destination image, tourism memory, satisfaction and loyalty and explores domestic and international tourists. The data were collected from tourists visiting the Algarve, Portugal, in 2021. A multi-group analysis determined the main differences between domestic and international tourists. The results show that the tourist experience has five dimensions: active learning, emotional engagement, passive entertainment, immersive escape, and aesthetic appeal. Furthermore, tourism experiences of both domestic and international tourists positively affect the cognitive image of the Algarve. There is a significant difference among domestic and international tourists regarding the impact of tourism memory on tourists' loyalty. Theoretical and managerial implications, limitations, and potential directions for future research are discussed. [ABSTRACT FROM AUTHOR]
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- 2025
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7. Green banking awareness and its association with green attitude, green trust, and green loyalty.
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Rocha, Viviane, Viegas, Cristina, Guerreiro, Manuela, Viola, Thiago Wendt, and Kluwe-Schiavon, Bruno
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BANKING industry ,SUSTAINABLE development ,CUSTOMER loyalty ,STRUCTURAL equation modeling ,INTERNET surveys - Abstract
The lack of consumer awareness regarding Green Banking Practices (GBP) poses a challenge for banks aiming to benefit from them and for sustainable development. This paper developed a scale for exploring the Green Banking Awareness (GBA) among Brazilian highly educated consumers and its association with Green Attitude (GA), Green Trust (GT), and Green Loyalty (GL). 414 participants answered an online survey. Descriptive analyses, principal component analysis, and structural equation modelling approaches were used to verify the item's structure and the relationship between variables. Although the respondents agree that they are environmentally conscious, most did not recognize the GBP in their banks. We observed that GA did not significantly correlate with GL and GT, but GBA significantly correlated with GT and GL. Also, GA was associated with education. Our results might help the bank industry, the finance regulators, and governments to better understand GBA and act to increase it. [ABSTRACT FROM AUTHOR]
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- 2025
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8. From Tourist Experience to Satisfaction and Loyalty: Exploring the Role of a Sense of Well-Being.
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Bagheri, Fatemeh, Guerreiro, Manuela, Pinto, Patrícia, and Ghaderi, Zahed
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EXPLORATORY factor analysis , *STRUCTURAL equation modeling , *SATISFACTION , *WELL-being , *SCALING (Social sciences) , *LOYALTY , *TOURIST attitudes , *HAPPINESS - Abstract
Drawing on the authentic happiness theory, the aims of this article are three-fold: first, to propose a refined measurement scale for tourists' sense of well-being; second, to investigate the impact of four categories of tourist experience on tourists' sense of well-being; and third, to explore the effect of the sense of well-being on tourists' satisfaction and loyalty. Data were collected from tourists spending their holidays in the Algarve, Portugal. To address the lack of an integrated measurement scale for assessing tourists' sense of well-being, an exploratory factor analysis was initially conducted. Subsequently, the data were analyzed using structural equation modeling in WarpPLS 8.0. The findings reveal a three-dimensional scale for tourists' sense of well-being, consisting of meaningfulness, active pleasure, and release. The results also show a significant positive impact of the four realms of tourists' experiences on the sense of well-being. Finally, positive relationships between well-being, tourist satisfaction and loyalty are confirmed. The theoretical and practical implications, limitations, and potential directions for future research are discussed. [ABSTRACT FROM AUTHOR]
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- 2024
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9. Impact of Neuropsychological Assessment on Subjective Memory Complaints in Patients With Mild Cognitive Impairment.
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Anjos, Ricardo, Madruga, Nuno, Cardoso, Sandra, Schmand, Ben, Guerreiro, Manuela, de Mendonça, Alexandre, and Ribeiro, Filipa
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ALZHEIMER'S disease ,EXECUTIVE function ,COGNITION disorders ,NEUROPSYCHOLOGICAL tests ,CASE-control method ,MEMORY disorders ,MENTAL depression ,DISEASE complications - Abstract
Introduction: Patients with Alzheimer's disease (AD), namely at an initial stage like amnestic cognitive impairment (aMCI), typically present with memory complaints. They also have difficulties regarding self‐knowledge about their cognitive deficits. In clinical practice, a formal neuropsychological assessment is often done. The present study aimed to understand whether patients with aMCI retain the ability to monitor the success or failure in their performance during the neuropsychological assessment and adjust the report of memory complaints accordingly, as compared to healthy controls. Methods: Participants were patients with aMCI and healthy controls who were questioned about their own memory abilities using the Subjective Memory Complaints (SMC) scale, applied before and after the neuropsychological assessment protocol. A repeated measures General Linear Model was performed to analyze changes in SMC (within‐subjects effects) after the neuropsychological assessment, in patients with aMCI and healthy controls (between‐subjects effects). Results: Eighty volunteers, 40 patients with aMCI and 40 healthy controls, participated in the study. Patients with aMCI showed lower MMSE scores, more depressive symptoms, and deficits in memory and learning, language and executive domains. Patients with aMCI had higher SMC scores [9.4(3.6)] than healthy controls [4.4(2.3)] before the neuropsychological assessment. A statistically significant interaction was found between the SMC and the diagnostic group, meaning that healthy controls decreased SMC [3.4(1.9)] after the neuropsychological assessment, whereas patients with aMCI kept high levels of SMC [9.6(3.9)]. In patients with aMCI, an inverse correlation between logical memory and the change in SMC was found, so that patients with lower scores in the logical memory test tended to increase their memory complaints after the assessment. Conclusions: Both patients with aMCI and healthy controls can monitor and update the impression about their memory abilities following a formal neuropsychological assessment. Patients with aMCI maintain a high SMC level, which is inversely associated with their memory performance. In practical terms, SMC should be measured consistently at a particular moment in time, preferably preceding the objective neuropsychological assessment. [ABSTRACT FROM AUTHOR]
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- 2024
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10. Memory awareness in patients with Major Depressive Disorder
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Mendes, Tiago, Cardoso, Sandra, Guerreiro, Manuela, Maroco, João, Silva, Dina, Alves, Luísa, Schmand, Ben, Simões do Couto, Frederico, Figueira, Maria Luísa, and de Mendonça, Alexandre
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- 2021
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11. The interplay of marketing and design
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Henseler, Jörg, Guerreiro, Manuela, and de Matos , Nelson
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- 2021
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12. Building bridges between residents and tourism: Attitudinal support, emotional solidarity, and intentions for pro-tourism behaviours.
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Lança, Milene, Pereira, Luís Nobre, Renda, Ana Isabel, Pinto, Patrícia, Marques, João Filipe, Ramos, Célia, Guerreiro, Manuela, and Lai, Hio Kuan
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SOCIAL exchange ,THEORY of reasoned action ,STRUCTURAL equation modeling ,PERCEIVED benefit ,SOCIAL influence - Abstract
Copyright of Tourism & Management Studies is the property of Escola Superior de Gestao, Hotelaria e Turismo, Universidade do Algarve and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2024
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13. The online destination image as portrayed by the user-generated content on social media and its impact on tourists' engagement.
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Guerreiro, Manuela, Pinto, Patrícia, Ramos, Célia M. Q., Matos, Nelson, Golestaneh, Homayoun, Sequeira, Bernardete, Pereira, Luís Nobre, Agapito, Dora, Martins, Rafaela, and Wijkesjö, Magda
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USER-generated content ,SENTIMENT analysis ,SOCIAL media ,TOURIST attractions ,IMAGE analysis ,TOURISTS ,DESTINATION image (Tourism) - Abstract
Copyright of Tourism & Management Studies is the property of Escola Superior de Gestao, Hotelaria e Turismo, Universidade do Algarve and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2024
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14. Amyloid-Negative, Neurodegeneration-Negative Amnestic Mild Cognitive Impairment.
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Cardoso, Sandra, Guerreiro, Manuela, Montalvo, Alexandre, Silva, Dina, Alves, Luísa, and de Mendonça, Alexandre
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AMNESTIC mild cognitive impairment , *GERIATRIC Depression Scale , *ALZHEIMER'S disease , *COGNITIVE testing , *NEUROPSYCHOLOGICAL tests - Abstract
Background: The concept of amnestic mild cognitive impairment (aMCI) was developed to identify patients at an initial stage of Alzheimer's disease (AD). However, some patients with aMCI do not present biomarkers of amyloid pathology or neuronal injury. Objective: To know the natural history of amyloid-negative and neurodegeneration-negative patients with aMCI, namely to ascertain: 1) whether these patients remain cognitively stable or they present a slow decline in neuropsychological tests; 2) whether the memory complaints subside with the apparently benign clinical course of the disorder or if they persist along the time. Methods: Patients who fulfilled criteria for aMCI with no biomarkers of amyloid pathology or neuronal injury were selected from a large cohort of non-demented patients with cognitive complaints, and were followed with clinical and neuropsychological assessments. Results: Twenty-one amyloid-negative and neurodegeneration-negative aMCI patients were followed for 7.1±3.7 years. At the baseline they had more pronounced deficits in verbal learning (California Verbal Learning Test) and were also impaired in Word Recall and Logical Memory. However, they did not decline in any cognitive test during follow-up. The patients maintained a high level of subjective memory complaints from baseline (9.7±4.1) to the follow-up visit (9.2±4.1, a non-significant difference), in spite of a statistically significant decrease in the depressive symptoms, with Geriatric Depression Scale (15 items) score 4.9±2.8 at baseline and 3.2±1.8 at the follow-up visit. Conclusions: Amyloid-negative, neurodegeneration-negative aMCI is a chronic clinical condition characterized by the long-term persistence of cognitive deficits and distressing memory complaints. Adequate strategies to treat this condition are needed. [ABSTRACT FROM AUTHOR]
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- 2024
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15. Targeting the uncertainty of predictions at patient-level using an ensemble of classifiers coupled with calibration methods, Venn-ABERS, and Conformal Predictors: A case study in AD
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Pereira, Telma, Cardoso, Sandra, Guerreiro, Manuela, Mendonça, Alexandre, de, and Madeira, Sara C.
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- 2020
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16. Different MMSE domains are associated to cognitive decline and education.
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Cardoso, Sandra, Barros, Ricardo, Marôco, João, de Mendonça, Alexandre, and Guerreiro, Manuela
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MILD cognitive impairment ,MINI-Mental State Examination ,COGNITION ,COGNITION disorders ,DEMENTIA patients - Abstract
The Mini-Mental State Examination (MMSE) is a long-established test to screen for dementia, estimate the severity and monitor the progression of cognitive impairment. The MMSE total score is dependent upon demographic factors, particularly education, but little is known about how education influences the 6 distinct MMSE cognitive domains. The present study aims to understand how the performances in the MMSE cognitive domains reflect clinical diagnosis and educational level. The study recruited 1043 participants, comprising 388 healthy controls, 360 patients with Mild Cognitive Impairment (MCI) and 295 patients with dementia. The association of the MMSE cognitive domains scores with clinical diagnosis (healthy, MCI, dementia) and educational level (primary education, middle school, high school and university/college) was analyzed with a multivariate ordinal regression model. The scores in all MMSE domains were generally higher in healthy controls as compared to patients with MCI, and higher in these as compared to patients with dementia. The MMSE domain Constructional ability was associated to the education level, the domains Orientation, Recall and Language were associated to diagnosis, Attention and calculation was associated to both education level and diagnosis, and Registration was not associated to either education or diagnosis. In conclusion, impairment in specific MMSE domains pinpoints cognitive decline, probably indicating brain areas affected by neurodegeneration, and impairment in others reflects lower education levels and the lack of acquisition of relevant schooling abilities. [ABSTRACT FROM AUTHOR]
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- 2024
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17. Impact of dementia on informal care: a systematic review of family caregivers' perceptions.
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Lindeza, Patrícia, Rodrigues, Mário, Costa, João, Guerreiro, Manuela, and Miguel Rosa, Mario
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- 2024
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18. Predicting alcohol relapse post‐detoxification: The role of cognitive impairments in alcohol use disorder patients.
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Teixeira, Joana, Pinheiro, Maria, Pereira, Gabriela Álvares, Nogueira, Paulo, Guerreiro, Manuela, Castanho, Miguel, and do Couto, Frederico Simões
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REHABILITATION of people with alcoholism ,RISK assessment ,DETOXIFICATION (Alternative medicine) ,T-test (Statistics) ,EXECUTIVE function ,LOGISTIC regression analysis ,FISHER exact test ,QUESTIONNAIRES ,CLASSIFICATION of mental disorders ,DESCRIPTIVE statistics ,CHI-squared test ,ODDS ratio ,COGNITION disorders ,ALCOHOL withdrawal syndrome ,MEMORY ,NEUROPSYCHOLOGICAL tests ,ANALYSIS of variance ,DISEASE relapse ,DATA analysis software ,CONFIDENCE intervals ,COGNITION ,DISEASE risk factors - Abstract
Background: Studies on early abstinence suggest that cognitive function is significantly reduced in the first year of abstinence, which raises the question of whether it is relevant to early relapse in patients with substance use disorders. This study investigates the extent to which impairments in executive function and memory predict alcohol relapse in patients with alcohol use disorder (AUD). Understanding these relationships is crucial for improving therapeutic approaches to prevent relapse in patients with AUD. Methods: We selected 116 adult patients (79 male and 37 female) diagnosed with AUD based on DSM‐5 criteria, all of whom were undergoing alcohol detoxification treatment. A comprehensive array of neuropsychological tests was administered to assess global cognition, memory, and executive functions. Patients' alcohol use was monitored monthly during a 6‐month follow‐up period. Logistic regression and Cox regression were used to explore the relationship between cognitive function and the likelihood of alcohol relapse. Results: Impairments in global cognition, semantic and phonemic fluency, cognitive flexibility, and learning ability during detoxification were significant predictors of relapse in AUD patients, showing similar predictive values at both 3 and 6 months post‐treatment. An abnormal Montreal Cognitive Assessment (MoCA) score increased the risk of relapse by 123% (HR: 2.227), and impairments in both semantic and phonemic fluency each increased the risk by 142% (HR: 2.423). Additionally, abnormal performance on the MoCA, Trail Making Test Part B (TMT‐B), and California Verbal Learning Test (CVLT) was associated with a higher number of drinking days at 3 months (IRR: 3.764; IRR: 2.237; IRR: 2.738, respectively) and abnormal MoCA and TMT‐B scores at 6 months (IRR: 2.451; IRR: 1.859, respectively). Conclusions: The MoCA test is a valuable tool for predicting relapse risk in AUD patients undergoing detoxification treatment, with similar predictive value for relapse at 3 or 6 months. Learning ability needs to be assessed and their impairments considered in the treatment of AUD patients. Future research should explore strategies for managing patients with impairments in memory and learning ability to enhance treatment effectiveness and prevent relapse. [ABSTRACT FROM AUTHOR]
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- 2024
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19. Pathophysiological subtypes of mild cognitive impairment due to Alzheimer's disease identified by CSF proteomics.
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Moutinho, Daniela, Mendes, Vera M., Caula, Alessandro, Madeira, Sara C., Baldeiras, Inês, Guerreiro, Manuela, Cardoso, Sandra, Gobom, Johan, Zetterberg, Henrik, Santana, Isabel, De Mendonça, Alexandre, Aidos, Helena, and Manadas, Bruno
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ALZHEIMER'S disease ,MILD cognitive impairment ,PROTEOMICS ,CEREBRAL amyloid angiopathy - Abstract
This article discusses a study that identified two subtypes of patients with mild cognitive impairment due to Alzheimer's disease (MCIAD) using proteomic analysis of cerebrospinal fluid (CSF). The study found that there were two distinct clusters of MCIAD patients, one associated with inflammatory and immune processes and the other with neurodevelopmental processes. The study also identified a protein signature that could potentially be used to assign patients to a specific cluster. However, the study had limitations in terms of the number of participants and the use of different sample preparation protocols. The findings have implications for the design and interpretation of clinical trials for Alzheimer's disease. [Extracted from the article]
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- 2024
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20. Sensory experiences in heritage contexts: A qualitative approach.
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Bender, Ana, Guerreiro, Manuela, Agapito, Dora, Dias Sequeira, Bernardete, and Mendes, Júlio
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This study explores the sensory experience at heritage sites from the visitors' perspective. A qualitative and exploratory approach was used, considering two data collection methods: semi-structured interviews and in situ focus groups. This empirical study was conducted in the Algarve region, a southern Portugal's sea and sun destination. The data was compiled and analyzed through a thematic content with QSR NVivo 12. The findings suggest that managers should explore and understand tangible, intangible (or immaterial) elements that influence visitors' experiences, attitudes, and behaviours toward the physical environment. In this sense, managers must converge efforts to highlight the sensory cues intrinsic to each site. Furthermore, considering the scarce research addressing sensory experiences in heritage contexts, this study contributes to the literature by exploring the role of the sensory dimension of experiencing a monument that is one of the main attractions in a seasonal mass tourism destination. A framework is presented, which can help managers to design sensory experiences in a built heritage context and assist researchers in future studies. In addition to that, this research also provides some practical implications for management and depicts several leads to future research. [ABSTRACT FROM AUTHOR]
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- 2024
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21. Heritage City Image Local Players' Perceptions.
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Mota, Miriam, Sequeira, Bernardete, Guerreiro, Manuela, and Pinto, Patrícia
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- 2024
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22. Conclusion.
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Scott, Noel, Guerreiro, Manuela, and Pinto, Patrícia
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- 2024
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23. Decrease in APP and CP mRNA expression supports impairment of iron export in Alzheimer's disease patients
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Guerreiro, Cláudia, Silva, Bruno, Crespo, Ângela C., Marques, Liliana, Costa, Sónia, Timóteo, Ângela, Marcelino, Erica, Maruta, Carolina, Vilares, Arminda, Matos, Mafalda, Couto, Frederico Simões, Faustino, Paula, Verdelho, Ana, Guerreiro, Manuela, Herrero, Ana, Costa, Cristina, de Mendonça, Alexandre, Martins, Madalena, and Costa, Luciana
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- 2015
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24. Genetic and biochemical markers in patients with Alzheimer's disease support a concerted systemic iron homeostasis dysregulation
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Crespo, Ângela C., Silva, Bruno, Marques, Liliana, Marcelino, Erica, Maruta, Carolina, Costa, Sónia, Timóteo, Ângela, Vilares, Arminda, Couto, Frederico Simões, Faustino, Paula, Correia, Ana Paula, Verdelho, Ana, Porto, Graça, Guerreiro, Manuela, Herrero, Ana, Costa, Cristina, de Mendonça, Alexandre, Costa, Luciana, and Martins, Madalena
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- 2014
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25. Introduction.
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Scott, Noel, Guerreiro, Manuela, and Pinto, Patrícia
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- 2024
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26. Neuropsychological predictors of conversion from mild cognitive impairment to Alzheimer’s disease: a feature selection ensemble combining stability and predictability
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Pereira, Telma, Ferreira, Francisco L., Cardoso, Sandra, Silva, Dina, de Mendonça, Alexandre, Guerreiro, Manuela, Madeira, Sara C., and for the Alzheimer’s Disease Neuroimaging Initiative
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- 2018
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27. The cultural offer as a tourist product in coastal destinations: The Case of Algarve, Portugal
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do Valle, Patrícia Oom, Guerreiro, Manuela, Mendes, Júlio, and Silva, João Albino
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- 2011
28. DESIGNING ACCESSIBLE TOURISM EXPERIENCES: SLOW, SENSORY AND SMART FRAMEWORK.
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Agapito, Dora and Guerreiro, Manuela
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ACCESSIBLE tourism ,ACCESSIBLE design ,SUSTAINABLE tourism ,EVIDENCE gaps ,GOVERNMENT aid - Abstract
Slow tourism is an emergent research area focused on slowing the pace of life during vacations. A comprehensive multi-sensory approach can contribute to designing enhanced slow tourism experiences deemed accessible, both in situ and remotely. There is a research gap in considering multi-sensory stimuli in the design of accessible tourism experiences using technology. As such, this research intends to propose a theoretical framework focused on the development of slow tourism through sensory cues and smart technologies. In so doing, a critical approach to literature was carried out by intersecting three areas of literature following the rationale of the Stimuli-Organism-Response model: slow tourism, multi-sensory tourism experiences design, and smart destinations. The significance of this framework is threefold: it strengthens local identities and aids sustainable tourism by involving the community; it promotes experiences deemed authentic considering multiple stakeholders' perspectives; and it addresses the visitor experience before, during and after the visit to the destination in an accessible manner using smart technologies. A framework with six steps is offered based on participatory methods. [ABSTRACT FROM AUTHOR]
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- 2023
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29. Retinal and cortical patterns of spatial anisotropy in contrast sensitivity tasks
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Silva, Maria Fatima, Maia-Lopes, Susana, Mateus, Catarina, Guerreiro, Manuela, Sampaio, Joana, Faria, Pedro, and Castelo-Branco, Miguel
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- 2008
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30. Non-literal language deficits in mild cognitive impairment
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Cardoso, Sandra, Silva, Dina, Maroco, João, de Mendonça, Alexandre, and Guerreiro, Manuela
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- 2014
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31. Time perspective and amnestic mild cognitive impairment.
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Coelho, Sara, de Mendonça, Alexandre, Maroco, João, Cardoso, Sandra, Mello, Zena, and Guerreiro, Manuela
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AMNESTIC mild cognitive impairment ,TIME perspective ,EXECUTIVE function ,MILD cognitive impairment ,NEUROPSYCHOLOGICAL tests - Abstract
Objective: We examined time perspective in patients with amnesic mild cognitive impairment (aMCI). Prior research has shown that aMCI is associated with difficulties in experiencing time duration and succession. However, this line of inquiry has not been extended to time perspective. We examined associations between aMCI and multiple dimensions of time perspective including perceived orientations and relationships among the past, present, and future. Method: Thirty aMCI patients and thirty‐three healthy controls participated. Measures were the Time Orientation Scale (TOS), the Time Relation Scale (TRS), and the Zimbardo Time Perspective Inventory (ZTPI), as well as a comprehensive neuropsychological evaluation. Results: The TRS was associated with aMCI. Patients with aMCI were more likely to perceive that time was unrelated than the healthy older adults. Among patients with aMCI, an unrelated time perspective was associated with poorer performance in executive function measures. However, aMCI was not associated with the TOS or the ZTPI. Conclusions: Patients with aMCI have difficulty in perceiving relationships among the past, present, and future. This could be the consequence of deficits in executive functions. This research suggests that patients with aMCI may have limited understanding for how their current behaviours are related to both their past and future. [ABSTRACT FROM AUTHOR]
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- 2022
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32. Cognitive and emotional consequences of perimesencephalic subarachnoid hemorrhage
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Madureira, Sofia, Canhão, Patrícia, Guerreiro, Manuela, and Ferro, José M.
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- 2000
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33. The Outcome of Patients with Amyloid-Negative Amnestic Mild Cognitive Impairment.
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Cardoso, Sandra, Silva, Dina, Alves, Luísa, Guerreiro, Manuela, and de Mendonça, Alexandre
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Background: Patients with amnestic mild cognitive impairment (aMCI) are usually at an initial stage of Alzheimer's disease (AD). However, some patients with aMCI do not present biomarkers of amyloid pathology characteristic of AD. The significance of amyloid-negative aMCI is not presently clear.Objective: To know the etiology and prognosis of amyloid-negative aMCI.Methods: Patients who fulfilled criteria for aMCI and were amyloid negative were selected from a large cohort of non-demented patients with cognitive complaints and were followed with clinical and neuropsychological assessments.Results: Few amyloid-negative aMCI had evidence of neurodegeneration at the baseline, as reflected in cerebrospinal fluid elevated tau protein levels. About half of the patients remained essentially stable for long periods of time. Others manifested a psychiatric disorder that was not apparent at baseline, namely major depression or bipolar disorder. Remarkably, about a quarter of patients developed neurodegenerative disorders other than AD, mostly frontotemporal dementia or Lewy body disease.Conclusion: Amyloid-negative aMCI is a heterogeneous condition. Many patients remain clinically stable, but others may later manifest psychiatric conditions or evolve to neurodegenerative disorders. Prudence is needed when communicating to the patient and family the results of biomarkers, and clinical follow-up should be advised. [ABSTRACT FROM AUTHOR]- Published
- 2022
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34. Effects of word length and word frequency among dyslexic, ADHD-I and typical readers.
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Pereira, Norberto, Costa, Maria Armanda, and Guerreiro, Manuela
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WORD frequency ,CHILDREN with dyslexia ,DYSLEXIA ,SILENT reading ,ARTICULATION disorders ,PSYCHOLINGUISTICS ,ORTHOGRAPHY & spelling - Abstract
This study aimed to investigate the neuropsycholinguistic functioning of children with Developmental Dyslexia (DD) and Attention-Deficit/Hyperactivity Disorder - inattentive subtype (ADHD-I) in a reading task. The psycholinguistic profile of both groups was assessed using a battery of neuropsychological and linguistic tests and compared to typical readers. Participants were submitted to a silent reading task with lexical manipulation of the text. Eye movements were recorded and compared aiming to find cognitive processes involved in reading that could help differentiate groups. The study examined whether word-frequency and word-length effects distinguish between groups. Participants included 19 typical readers, 21 children diagnosed with ADHD-I and 19 children with DD. All participants were attending 4th grade and had a mean age of 9.08 years. Children with DD and ADHDI exhibited significant different cognitive and linguistic profiles on almost all measures evaluated when compared to typical readers. The effects of word length and word frequency interaction also differed significantly in the 3 experimental groups. The results support the multiple cognitive deficits theory. While the shared deficits support the evidence of a phonological disorder present in both conditions, the specific ones corroborate the hypothesis of an oculomotor dysfunction in DD and a visuo-spatial attention dysfunction in ADHD. [ABSTRACT FROM AUTHOR]
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- 2022
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35. Mild Cognitive Impairment: Focus on Diagnosis
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de Mendonça, Alexandre, Guerreiro, Manuela, Ribeiro, Filipa, Mendes, Tiago, and Garcia, Carlos
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- 2004
36. Data mining methods in the prediction of Dementia: A real-data comparison of the accuracy, sensitivity and specificity of linear discriminant analysis, logistic regression, neural networks, support vector machines, classification trees and random forests
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Santana Isabel, Guerreiro Manuela, Rodrigues Ana, Silva Dina, Maroco João, and de Mendonça Alexandre
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Medicine ,Biology (General) ,QH301-705.5 ,Science (General) ,Q1-390 - Abstract
Abstract Background Dementia and cognitive impairment associated with aging are a major medical and social concern. Neuropsychological testing is a key element in the diagnostic procedures of Mild Cognitive Impairment (MCI), but has presently a limited value in the prediction of progression to dementia. We advance the hypothesis that newer statistical classification methods derived from data mining and machine learning methods like Neural Networks, Support Vector Machines and Random Forests can improve accuracy, sensitivity and specificity of predictions obtained from neuropsychological testing. Seven non parametric classifiers derived from data mining methods (Multilayer Perceptrons Neural Networks, Radial Basis Function Neural Networks, Support Vector Machines, CART, CHAID and QUEST Classification Trees and Random Forests) were compared to three traditional classifiers (Linear Discriminant Analysis, Quadratic Discriminant Analysis and Logistic Regression) in terms of overall classification accuracy, specificity, sensitivity, Area under the ROC curve and Press'Q. Model predictors were 10 neuropsychological tests currently used in the diagnosis of dementia. Statistical distributions of classification parameters obtained from a 5-fold cross-validation were compared using the Friedman's nonparametric test. Results Press' Q test showed that all classifiers performed better than chance alone (p < 0.05). Support Vector Machines showed the larger overall classification accuracy (Median (Me) = 0.76) an area under the ROC (Me = 0.90). However this method showed high specificity (Me = 1.0) but low sensitivity (Me = 0.3). Random Forest ranked second in overall accuracy (Me = 0.73) with high area under the ROC (Me = 0.73) specificity (Me = 0.73) and sensitivity (Me = 0.64). Linear Discriminant Analysis also showed acceptable overall accuracy (Me = 0.66), with acceptable area under the ROC (Me = 0.72) specificity (Me = 0.66) and sensitivity (Me = 0.64). The remaining classifiers showed overall classification accuracy above a median value of 0.63, but for most sensitivity was around or even lower than a median value of 0.5. Conclusions When taking into account sensitivity, specificity and overall classification accuracy Random Forests and Linear Discriminant analysis rank first among all the classifiers tested in prediction of dementia using several neuropsychological tests. These methods may be used to improve accuracy, sensitivity and specificity of Dementia predictions from neuropsychological testing.
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- 2011
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37. Neuropsychological profile of amyloid‐positive versus amyloid‐negative amnestic Mild Cognitive Impairment.
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Alves, Luísa, Cardoso, Sandra, Silva, Dina, Mendes, Tiago, Marôco, João, Nogueira, Joana, Lima, Marisa, Tábuas‐Pereira, Miguel, Baldeiras, Inês, Santana, Isabel, Mendonça, Alexandre, and Guerreiro, Manuela
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AMNESTIC mild cognitive impairment ,TRAIL Making Test ,NEUROPSYCHOLOGICAL tests ,LOGISTIC regression analysis ,MEMORY testing - Abstract
Introduction: Patients diagnosed with amnestic mild cognitive impairment (aMCI) are at high risk of progressing to dementia. It became possible, through the use of biomarkers, to diagnose those patients with aMCI who have Alzheimer's disease. However, it is presently unfeasible that all patients undergo biomarker testing. Since neuropsychological testing is required to make a formal diagnosis of aMCI, it would be interesting if it could be used to predict the amyloid status of patients with aMCI. Methods: Participants with aMCI, known amyloid status (Aβ+ or Aβ−) and a comprehensive neuropsychological evaluation, were selected from the Cognitive Complaints Cohort database for this study. Neuropsychological tests were compared in Aβ+ and Aβ− aMCI patients. A binary logistic regression analysis was conducted to model the probability of being amyloid positive. Results: Of the 216 aMCI patients studied, 117 were Aβ+ and 99 were Aβ−. Aβ+ aMCI patients performed worse on several memory tests, namely Word Total Recall, Logical Memory Immediate and Delayed Free Recall, and Verbal Paired Associate Learning, as well as on Trail Making Test B, an executive function test. In a binary logistic regression model, only Logical Memory Delayed Free Recall retained significance, so that for each additional score point in this test, the probability of being amyloid positive decreased by 30.6%. The resulting model correctly classified 64.6% of the aMCI cases regarding their amyloid status. Conclusions: The neuropsychological assessment remains an essential step to diagnose and characterize patients with aMCI; however, neuropsychological tests have limited value to distinguish the aMCI patients who have amyloid pathology from those who might suffer from other clinical conditions. [ABSTRACT FROM AUTHOR]
- Published
- 2021
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38. The update of semantic memories in amnestic mild cognitive impairment.
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Mendonça, Alexandre, Cardoso, Sandra, Maroco, João, Guerreiro, Manuela, and Carmo, Joana C.
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SEMANTIC memory ,AMNESTIC mild cognitive impairment ,EPISODIC memory ,TEMPORAL lobe - Abstract
It is still controversial to what extent neocortical consolidated memories are susceptible of change by processes of reconsolidation and transformation throughout experience, and whether the medial temporal lobes are necessary for this update of semantic consolidated memories, as they are for episodic remembering. We hypothesize that patients with amnestic mild cognitive impairment (aMCI) who have deficits in episodic memory may also have difficulties in updating information on added new features of objects. Sixteen participants with aMCI and 20 healthy control participants performed a semantic word‐to‐picture task, in which they were asked to identify as belonging to a given semantic category NEW objects, that have incorporated novel features, as well as OLD items, semantically and visually SIMILAR items and UNRELATED items. Patients with aMCI made a greater percentage of errors than healthy controls. Participants globally made greater percentages of errors in difficult types of items, namely NEW and SIMILAR, as compared to easier ones, OLD and UNRELATED. Importantly, an item by diagnostic group interaction effect was observed, and post hoc analysis showed that patients with aMCI made a higher percentage of errors than controls in NEW items only. In conclusion, patients with aMCI had a particular difficulty in identifying the NEW items of the word‐to‐picture task as compared to the control participants, supporting the concept of a flexible and dynamic conceptual knowledge system, involving the update of semantic memories and the integration of new attributes in a constant transformation process, which is impaired in these patients. [ABSTRACT FROM AUTHOR]
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- 2021
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39. Drivers of eWOM intensity: differences between hoteliers' perception and real reviews.
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Perez-Aranda, Javier, Guerreiro, Manuela, and da Costa Mendes, Júlio
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This study aims to determine whether eWOM intensity is related to use intensity, commitment, and competence of brands' review sites. The study is applied to hotels on TripAdvisor and compares brand's perception and real effects. Results of a survey of 332 hotels listed on TripAdvisor are compared with data collected from TripAdvisor. The method consists of comparing these data with the perception of hoteliers, to determine if the drivers use intensity, commitment, and competence have similar effects on eWOM intensity. Regarding correlation analysis, some similarities are found, all drivers included in both models are positively correlated with each explained variable. However, regression analysis revealed differences between drivers of eWOM intensity when the explained variable is based on hoteliers' perception instead of objective data. While, no variable is significant when eWOM intensity is based on perception, the variable use intensity shows a significant relation, when eWOM intensity is assessed by actual reviews. The findings suggest that use intensity is a determinant factor of eWOM intensity. Furthermore, differences between brands' perception and real reviews are observed. [ABSTRACT FROM AUTHOR]
- Published
- 2021
40. Design and marketing: Intersections and challenges.
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Henseler, Jörg and Guerreiro, Manuela
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MARKETING research ,DESIGN research ,INTERDISCIPLINARY research ,MARKETING ,REALISM - Abstract
This editorial article reports on interdisciplinary research being conducted at the interface between the scientific disciplines of marketing and design. It reviews the 11 academic papers from the special issue situated at this intersection, thereby showing the richness of research happening in this liminal area. At the same time, the paper observes how the disciplines' different scopes as well as their different modi operandi inhibit the collaboration between marketing and design research. Whereas marketing largely follows the paradigm of empirical realism asking how the current world works, design largely follows the pragmatist paradigm asking how a future world can be shaped. Finally, this paper contains a number of suggestions on how to foster cooperation between the two disciplines. [ABSTRACT FROM AUTHOR]
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- 2020
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41. Neuropsychological Contribution to Predict Conversion to Dementia in Patients with Mild Cognitive Impairment Due to Alzheimer's Disease.
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Silva, Dina, Cardoso, Sandra, Guerreiro, Manuela, Maroco, João, Mendes, Tiago, Alves, Luísa, Nogueira, Joana, Baldeiras, Inês, Santana, Isabel, de Mendonça, Alexandre, and Beach, Thomas
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MILD cognitive impairment ,ALZHEIMER'S disease ,DEMENTIA patients ,EPISODIC memory ,COGNITION disorders ,ALZHEIMER'S disease diagnosis ,THOUGHT & thinking ,DISEASE progression ,MEMORY ,RESEARCH ,PREDICTIVE tests ,RESEARCH methodology ,PSYCHOLOGY of movement ,EVALUATION research ,SOCIOECONOMIC factors ,COMPARATIVE studies ,KAPLAN-Meier estimator ,LONGITUDINAL method - Abstract
Background: Diagnosis of Alzheimer's disease (AD) confirmed by biomarkers allows the patient to make important life decisions. However, doubt about the fleetness of symptoms progression and future cognitive decline remains. Neuropsychological measures were extensively studied in prediction of time to conversion to dementia for mild cognitive impairment (MCI) patients in the absence of biomarker information. Similar neuropsychological measures might also be useful to predict the progression to dementia in patients with MCI due to AD.Objective: To study the contribution of neuropsychological measures to predict time to conversion to dementia in patients with MCI due to AD.Methods: Patients with MCI due to AD were enrolled from a clinical cohort and the effect of neuropsychological performance on time to conversion to dementia was analyzed.Results: At baseline, converters scored lower than non-converters at measures of verbal initiative, non-verbal reasoning, and episodic memory. The test of non-verbal reasoning was the only statistically significant predictor in a multivariate Cox regression model. A decrease of one standard deviation was associated with 29% of increase in the risk of conversion to dementia. Approximately 50% of patients with more than one standard deviation below the mean in the z score of that test had converted to dementia after 3 years of follow-up.Conclusion: In MCI due to AD, lower performance in a test of non-verbal reasoning was associated with time to conversion to dementia. This test, that reveals little decline in the earlier phases of AD, appears to convey important information concerning conversion to dementia. [ABSTRACT FROM AUTHOR]- Published
- 2020
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42. Mental time travel in mild cognitive impairment.
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Coelho, Sara, Guerreiro, Manuela, Chester, Catarina, Silva, Dina, Maroco, João, Paglieri, Fabio, and de Mendonça, Alexandre
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MILD cognitive impairment , *TIME travel , *SEMANTIC memory , *EPISODIC memory , *COGNITIVE ability , *DECISION making - Abstract
Introduction: Mental Time Travel (MTT) is the people's ability to remember themselves in the past and to imagine themselves in the future, and influence important life domains such as making decisions and planning future actions. It is widely recognized that patients with aMCI have deficits in episodic memory, but they also show impairments in semantic memory. It has been controversial whether MTT tasks are disturbed in aMCI mainly in relation to internal details related to episodic information, or external details, representing semantic and other extraneous information. The present study assessed whether patients with aMCI are affected in MTT regarding generation of internal details and external details, in past and future dimensions. Furthermore, it analyzed production in individual detail categories (internal: event details, thought/emotion, place, time, perceptual; external: extraneous events, semantic, other, repetitions). Method: Twenty-nine patients with aMCI and 29 healthy controls underwent a MTT task based on an Autobiographical Interview, where they had to generate past and future events in response to cue words. Transcriptions were segmented and classified into internal detail categories and external detail categories, and composite scores were obtained. Results: Patients with aMCI could globally produce significantly less details than controls. Similar to controls, patients with aMCI produced more internal details than external details, had more difficulty in generating details regarding the future as compared to the past, and scored higher in the detail categories event details and thought/emotion which represent internal detail types. Conclusions: Patients with aMCI showed widespread deficits in MTT, presumably reflecting deficiencies in the complex and multiple cognitive abilities required for MTT tasks. [ABSTRACT FROM AUTHOR]
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- 2019
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43. Can Subjective Memory Complaints Identify Aβ Positive and Aβ Negative Amnestic Mild Cognitive Impairment Patients?
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Mendes, Tiago, Cardoso, Sandra, Guerreiro, Manuela, Maroco, João, Silva, Dina, Alves, Luísa, Schmand, Ben, Gerardo, Bianca, Lima, Marisa, Santana, Isabel, and de Mendonça, Alexandre
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MILD cognitive impairment ,AMNESTIC mild cognitive impairment ,GERIATRIC Depression Scale ,NEUROPSYCHOLOGICAL tests ,SELF diagnosis ,MEMORY disorders ,PEPTIDES ,LONGITUDINAL method ,AMNESIA - Abstract
Background: The use of biomarkers, in particular amyloid-β (Aβ) changes, has allowed the possibility to identify patients with subjective memory complaints (SMCs) and amnestic mild cognitive impairment (aMCI) who suffer from Alzheimer's disease (AD). Since it is unfeasible that all patients with aMCI could presently undergo biomarkers assessment, it would be important that SMCs might contribute to identify the aMCI patients who have AD amyloid pathology.Objectives: To know whether aMCI patients with amyloid biomarkers (Aβ+) present greater SMCs as compared to those without amyloid biomarkers (Aβ-).Methods: Participants were selected from a cohort of nondemented patients with cognitive complaints and a comprehensive neuropsychological evaluation, on the basis of 1) diagnosis of aMCI; 2) detailed assessment of memory difficulties with the SMC Scale; and 3) known amyloid status. The amyloid status was determined on the basis of either CSF Aβ1-42 concentration or amyloid PET imaging.Results: Of the 176 patients with aMCI studied, 90 were Aβ+ and 86 were Aβ-. The two groups did not differ in terms of age, gender, and education. The SMC total score was not significantly different in the Aβ+ aMCI patients (9.48±4.18) when compared to the Aβ- aMCI patients (10.52±4.57). The Aβ+ aMCI patients had lower scores on the MMSE and memory/learning tests, but not on the Geriatric Depression Scale, when comparing to the Aβ- aMCI patients.Conclusions: Evaluating SMCs does not seem helpful to identify, among patients with aMCI, those who have AD. [ABSTRACT FROM AUTHOR]- Published
- 2019
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44. Memory complaints in amnestic Mild Cognitive Impairment: More prospective or retrospective?
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de Mendonça, Alexandre, Felgueiras, Helena, Verdelho, Ana, Câmara, Sara, Grilo, Cláudia, Maroco, João, Pereira, Antonina, and Guerreiro, Manuela
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MILD cognitive impairment ,ALZHEIMER'S disease ,MENTAL health ,SHORT-term memory ,LONG-term memory - Abstract
Objective: Patients with amnestic Mild Cognitive Impairment (aMCI), usually considered an early stage of Alzheimer's disease, have deficits not only in retrospective memory (RM), that is, recalling of past events, words or people, but also on prospective memory (PM), the cognitive ability of remembering to execute delayed intentions in the future. This study investigated whether patients with aMCI refer more PM complaints as compared with RM complaints, and whether this might depend upon short-term vs long-term items or time-based vs event-based tasks.Methods: Patients with aMCI (n = 178) and healthy controls (n = 160) underwent the Prospective and Retrospective Memory Questionnaire (PRMQ), a 16-item instrument to appraise differences between PM and RM complaints, as well as a general mental state examination, a subjective memory complaints questionnaire, objective memory tests, and assessment of depressive symptoms and activities of daily living.Results: Patients with aMCI reported more memory complaints evaluated with the PRMQ (total score = 44.3 ± 10.8) as compared with controls (36.7 ± 9.8, P < 0.001). Using a mixed effect repeated-measures analysis of covariance (ANCOVA) showed that participants generally referred more retrospective than prospective memory complaints. Patients with aMCI had significantly more complaints on short-term memory as compared with long-term memory, and more complaints in time-based (auto-initiated) as compared with event-based tasks, than healthy controls.Conclusion: Patients with aMCI reported significantly more difficulties on short-term memory, presumably reflecting internal temporal lobe pathology typical of Alzheimer's disease, and more complaints on time-based tasks, which are cognitively very demanding, but did not seem particularly troubled regarding prospective memory. [ABSTRACT FROM AUTHOR]- Published
- 2018
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45. Neuropsychological Predictors of Long-Term (10 Years) Mild Cognitive Impairment Stability.
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Alves, Luísa, Cardoso, Sandra, de Mendonça, Alexandre, Guerreiro, Manuela, Maroco, João, and Silva, Dina
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AMNESTIC mild cognitive impairment ,NEUROPSYCHOLOGY ,FOLLOW-up studies (Medicine) ,DEMENTIA ,COHORT analysis ,DIAGNOSIS ,COMPARATIVE studies ,LONGITUDINAL method ,NEUROPSYCHOLOGICAL tests ,RESEARCH methodology ,MEDICAL cooperation ,PROGNOSIS ,RESEARCH ,EVALUATION research ,DISEASE progression - Abstract
Background: Although the diagnosis of mild cognitive impairment (MCI) corresponds to a condition likely to progress to dementia, essentially Alzheimer's disease, longitudinal studies have shown that some patients may not convert to dementia and maintain the diagnosis of MCI even after many years.Objectives: To determine whether patients that maintain the diagnosis of MCI in the long term (10 years) are really stable or just declining slowly, and to identify clinical and neuropsychological characteristics associated with long-term stability.Methods: The Cognitive Complaints Cohort (CCC) was searched for MCI cases who maintained that diagnosis for at least 10 years. For each long-term-stable MCI patient, two MCI patients that converted to dementia during follow-up, matched for age and education, were selected from the same database. The baseline and last neuropsychological evaluations for long-term-stable MCI and converter MCI were compared. Baseline neuropsychological predictors of long-term stability were searched for.Results: Long-term-stable MCI (n = 22) and converter MCI (n = 44) patients did not differ in terms of gender distribution, education, age at first assessment and time between symptom onset and first evaluation. Time of follow-up was on average 11 years for long-term-stable MCI and 3 years for converter MCI. The baseline and follow-up neuropsychological tests were not significantly different in long-term-stable MCI patients, whereas a general decline was observed in converter MCI patients. Higher scores on one memory test, the Word Delayed Total Recall, and on the non-verbal abstraction test, Raven's Progressive Matrices, at the baseline predicted long-term (10 years) clinical stability.Conclusions: Some patients with MCI remain clinically and neuropsychologically stable for a decade. Better performances at baseline in memory and non-verbal abstraction tests predict long-term stability. [ABSTRACT FROM AUTHOR]- Published
- 2018
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46. Alzheimer's Disease Assessment Scale - Cognitive Subscale (ADAS-Cog): Normative Data for the Portuguese Population.
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NOGUEIRA, Joana, FREITAS, Sandra, DURO, Diana, TÁBUAS-PEREIRA, Miguel, GUERREIRO, Manuela, ALMEIDA, Jorge, and SANTANA, Isabel
- Published
- 2018
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47. Predicting progression of mild cognitive impairment to dementia using neuropsychological data: a supervised learning approach using time windows.
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Pereira, Telma, Lemos, Luís, Cardoso, Sandra, Silva, Dina, Rodrigues, Ana, Santana, Isabel, de Mendonça, Alexandre, Guerreiro, Manuela, and Madeira, Sara C.
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MILD cognitive impairment ,DEMENTIA ,NEUROPSYCHOLOGICAL tests ,MEDICAL appointments ,SUPERVISED learning ,DIAGNOSIS of dementia ,MATHEMATICAL models ,PROGNOSIS ,TIME ,THEORY ,DISEASE progression - Abstract
Background: Predicting progression from a stage of Mild Cognitive Impairment to dementia is a major pursuit in current research. It is broadly accepted that cognition declines with a continuum between MCI and dementia. As such, cohorts of MCI patients are usually heterogeneous, containing patients at different stages of the neurodegenerative process. This hampers the prognostic task. Nevertheless, when learning prognostic models, most studies use the entire cohort of MCI patients regardless of their disease stages. In this paper, we propose a Time Windows approach to predict conversion to dementia, learning with patients stratified using time windows, thus fine-tuning the prognosis regarding the time to conversion.Methods: In the proposed Time Windows approach, we grouped patients based on the clinical information of whether they converted (converter MCI) or remained MCI (stable MCI) within a specific time window. We tested time windows of 2, 3, 4 and 5 years. We developed a prognostic model for each time window using clinical and neuropsychological data and compared this approach with the commonly used in the literature, where all patients are used to learn the models, named as First Last approach. This enables to move from the traditional question "Will a MCI patient convert to dementia somewhere in the future" to the question "Will a MCI patient convert to dementia in a specific time window".Results: The proposed Time Windows approach outperformed the First Last approach. The results showed that we can predict conversion to dementia as early as 5 years before the event with an AUC of 0.88 in the cross-validation set and 0.76 in an independent validation set.Conclusions: Prognostic models using time windows have higher performance when predicting progression from MCI to dementia, when compared to the prognostic approach commonly used in the literature. Furthermore, the proposed Time Windows approach is more relevant from a clinical point of view, predicting conversion within a temporal interval rather than sometime in the future and allowing clinicians to timely adjust treatments and clinical appointments. [ABSTRACT FROM AUTHOR]- Published
- 2017
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48. Delay discounting in mild cognitive impairment.
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Coelho, Sara, Guerreiro, Manuela, Chester, Catarina, Silva, Dina, Maroco, João, Paglieri, Fabio, and de Mendonça, Alexandre
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MILD cognitive impairment , *DELAY discounting (Psychology) , *DECISION making , *NEUROPSYCHOLOGY , *STIMULUS & response (Psychology) - Abstract
Introduction: Patients with mild cognitive impairment (MCI) may make suboptimal decisions particularly in complex situations, and this could be due to temporal discounting, the tendency to prefer immediate rewards over delayed but larger rewards. The present study proposes to evaluate intertemporal preferences in MCI patients as compared to healthy controls.Method: Fifty-five patients with MCI and 57 healthy controls underwent neuropsychological evaluation and a delay discounting questionnaire, which evaluates three parameters: hyperbolic discounting (k), the percentage of choices for delayed and later rewards (%LL), and response consistency (Acc).Results: No significant differences were found in the delay discounting questionnaire between MCI patients and controls for the three reward sizes considered, small, medium, and large, using bothkand %LL parameters. There were also no differences in the response consistency, Acc, between the two groups.Conclusions: Patients with MCI perform similarly to healthy controls in a delay discounting task. Memory deficits do not notably affect intertemporal preferences. [ABSTRACT FROM PUBLISHER]
- Published
- 2017
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49. O CONTRIBUTO DA EXPERIÊNCIA GASTRONÓMICA PARA O ENRIQUECIMENTO DA EXPERIÊNCIA TURÍSTICA. PERSPETIVAS DE UM ESTUDO NO ALGARVE, PORTUGAL.
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Teresa Santos, Joana, dos Santos Pinto, Patrícia Susana Lopes Guerrilha, and Guerreiro, Manuela
- Abstract
Copyright of Turismo: Visão e Ação is the property of Turismo-Visao E Acao and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2016
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50. Time Perception in Mild Cognitive Impairment: Interval Length and Subjective Passage of Time.
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Coelho, Sara, Guerreiro, Manuela, Chester, Catarina, Silva, Dina, Maroco, João, Coelho, Miguel, Paglieri, Fabio, and Mendonça, Alexandre de
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MILD cognitive impairment , *TIME perception , *MEMORY , *NEUROPSYCHOLOGICAL tests , *ANXIETY , *PATIENTS - Abstract
Objectives: Patients with mild cognitive impairment (MCI) may have difficulties in time perception, which in turn might contribute to some of their symptoms, especially memory deficits. The aim of this study was to evaluate perception of interval length and subjective passage of time in MCI patients as compared to healthy controls. Methods: Fifty-five MCI patients and 57 healthy controls underwent an experimental protocol for time perception on interval length, a questionnaire for the subjective passage of time and a neuropsychological evaluation. Results: MCI patients presented no changes in the perception of interval length. However, for MCI patients, time seemed to pass more slowly than it did for controls. This experience was significantly correlated with memory deficits but not with performance in executive tests, nor with complaints of depression or anxiety. Conclusions: Memory deficits do not affect the perception of interval length, but are associated with alterations in the subjective passage of time. [ABSTRACT FROM AUTHOR]
- Published
- 2016
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