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Since the 20th century, global climate has been recognized as the most important environmental factor affecting the distribution of plants. Angelica dahurica (A. dahurica) has been in great demand as a medicinal herb and flavoring, but the lack of seed sources has hindered its development. In this study, we utilized the Maxent model combined with Geographic Information System (GIS) to predict the potential habitat of A. dahurica in China based on its geographical distribution and 22 environmental factors. This prediction will serve as a valuable reference for the utilization and conservation of A. dahurica resources.The results indicated that: (1) the Maxent model exhibited high accuracy in predicting the potential habitat area of A. dahurica, with a mean value of the area under the ROC curve (AUC) at 0.879 and a TSS value above 0.6; (2) The five environmental variables with significant effects were bio6 (Min temperature of the coldest month), bio12 (Annual Precipitation), bio17 (Precipitation of Driest Quarter), elevation, and slope, contributing to a cumulative total of 89.6%. Suitable habitats for A. dahurica were identified in provinces such as Yunnan, Guizhou, Guangxi, Sichuan, Hunan, and others. The total area of suitable habitat was projected to increase, with expansion primarily in middle and high latitudes, while areas of decrease were concentrated in lower latitudes. Under future climate change scenarios, the centers of mass of suitable areas for A. dahurica were predicted to shift towards higher latitudes in the 2050s and 2090s, particularly towards the North China Plain and Northeast Plain. Overall, it holds great significance to utilize the Maxent model to predict the development and utilization of A. dahurica germplasm resources in the context of climate change.

Innovation is the source of economic growth. Innovation in a region comes from its own knowledge creation and knowledge spillovers from other regions. Previous studies showed that R&D factors flow benefits knowledge spillover, thereby promoting economic growth. But these studies ignored the impact of a region's knowledge-absorptive capacity on knowledge spillovers. Ignoring the impact of regional absorptive capacity means that the knowledge spillover from the same R&D factors flow is the same, clearly inconsistent with reality. This thesis analyzes the impact of R&D factors flow on economic growth and explores the moderating effect of regional absorptive capacity on the relationship between R&D factors flow and economic growth from theoretical and empirical perspectives. First, we construct a knowledge creation and diffusion model of the new economic geography, including regional absorptive capacity, and analyze the theoretical logic of the flow of R&D factors and regional absorptive capacity influencing economic growth. Second, we employ spatial econometric models to examine the impact of R&D factors flow and regional absorptive capacity on economic growth, utilizing panel data of 30 provinces in China from 2008 to 2021. The results demonstrated a spatial positive correlation between regional economic growth in China. The R&D factors flow could have significantly promoted not just a region's direct economic growth, but also the economic growth of surrounding regions via spatial spillover effects. Furthermore, the stronger the regional absorptive capacity, the greater the direct effects and spatial spillover effects of the R&D factors flow on economic growth. The novelty of this article is to introduce regional absorptive capacity into the theoretical model, refine the methodology for assessing regional absorptive capacity in empirical research, and examine its moderating effect between the inflow of R&D factors and regional economic growth. This article reveals that the positive impact of the inflow of R&D factors on spatial spillovers and economic growth varies depending on regional absorptive capacity. According to the conclusions above, enhancing regional absorptive capacity is equally important as facilitating the flow of R&D factors. Therefore, it is vital for a region to strengthen its absorptive capacity for new knowledge while promoting R&D factors flow. The study provides valuable policy insights for accelerating the flow of innovation factors, enhancing regional absorptive capacity, and consequently promoting long-term sustainable economic development in the region.

Objective: The worldwide prevalence of anemia is ~24.8%. Iron deficiency anemia is common in children and women and associated with sensory, motor, cognitive, language, and socioemotional deficits. Therefore, detection and early intervention strategies for anemia in infants are urgently needed. To prevent the occurrence of iron deficiency anemia, we aimed to identify risk factors associated with anemia in infants.Methods: This investigation involved a cross-sectional study of 6-months-old infants discharged between April 2014 and September 2017 from Peking University First Hospital. We assessed birth information, maternal age, and maternal educational level as well as data on feeding style, complementary foods and primary caregivers. The infants were assessed with the Denver Developmental Screening Test (DDST).Results: A total of 1,127 6-months-old infants were enrolled at the hospital. We found that the prevalence of anemia among infants in Beijing was ~11.8%. Premature infants had a higher rate of anemia than full-term infants (χ2 = 40.103, P < 0.001). Infants born in autumn or winter were at an elevated risk of developing anemia (χ2 = 22.949, P < 0.001). Birth weight had no effect on the rate of anemia in infants (χ2 = 0.023, P = 0.568). Infants who were exclusively breastfeeding had higher anemia rates than those who were fed formula (χ2 = 38.466, P < 0.001). Infants whose caregivers added no complementary foods had higher anemia rates (24.7%) than those whose caregivers added more than two kinds of complementary food (8.2%). The type of caregiver had no effect on the anemia rate in infants (χ2 = 0.031, P = 1.000).Conclusions: The following factors resulted in a higher prevalence of anemia in our study a gestational age at birth of

ObjectiveAn increasing number of parents in China ask grandparents or babysitters to care for their children. Modern parents are often the only child in their family because of China’s One-Child Policy and thus may lack interaction with siblings. Accordingly, the present study aimed to explore whether different caregivers affect the physical and development of infants in China.MethodsIn total, 2,514 infants were enrolled in our study. We assessed their weight-for-age, supine length-for-age, weight-for-length, occipital-frontal circumference, and Denver Developmental Screening Test (DDST) results and recorded their general parental information and their primary caregivers.ResultsThe weights and lengths of 12-month-old infants under the care of babysitters were significantly lower than those of infants under the care of parents or grandparents (P

Objective: This study aims to investigate the relationship between serum vitamin D, total IgE levels and chronic spontaneous urticaria (CSU). Methods: We collected data from 101 patients with chronic spontaneous urticaria (experimental group) and 115 healthy normal subjects (control group) in the same period of physical examination. Results: The results showed that the number of deficient and absolute deficient 25-hydroxyvitamin D in the experimental group was significantly lower than in the control group (P < 0.05). Pearson correlation analysis showed that the activity score of CSU patients was negatively correlated with serum vitamin D (r = -0.2278, P = 0.0220) and positively correlated with IgE (r = 0.2078, P = 0.0380). It was observed that serum vitamin D in CSU patients was negatively correlated with their activity (r = -0.2278, P = 0.0220) and positively correlated with age (r = 0.2675, P = 0.0069). The Point-biserial correlation analysis revealed that gender was positively correlated with serum vitamin D (Pearson correlation coefficient = 0.286, P = 0.004) and UAS score (Pearson correlation coefficient = 0.273, P = 0.006). Ordinal logistic regression analysis showed that only serum vitamin D was correlated to activity scores (P = 0.008). In addition to activity scores, age ( P = 0.005) and gender (P = 0.04) were correlated to serum vitamin D. Conclusion: The activity score of CSU patients was negatively correlated with serum vitamin D and positively correlated with IgE. Serum vitamin D in CSU patients was negatively correlated with activity score and disease duration and positively correlated with age and gender. [ABSTRACT FROM AUTHOR]

Background: Previous trials of iron supplementation in infancy did not consider maternal iron supplementation.Objective: This study assessed effects of iron supplementation in infancy and/or pregnancy on infant iron status, illnesses, and growth at 9 mo.Methods: Enrollment occurred from December 2009 to June 2012 in Hebei, China. Infants born to women in a pregnancy iron supplementation trial were randomly assigned 1:1 to iron [∼1 mg Fe/(kg · d) as oral iron proteinsuccynilate] or placebo from 6 wk to 9 mo, excluding infants with cord ferritin <35 μg/L. Study groups were pregnancy placebo/infancy placebo (placebo/placebo), pregnancy placebo/infancy iron (placebo/iron), pregnancy iron/infancy placebo (iron/placebo), and pregnancy iron/infancy iron (iron/iron). The primary outcome was 9-mo iron status: iron deficiency (ID) by cutoff (≥2 abnormal iron measures) or body iron <0 mg/kg and ID + anemia (hemoglobin <110 g/L). Secondary outcomes were doctor visits or hospitalizations and weight or length gain from birth to 9 mo. Statistical analysis by intention to treat and dose-response (between number of iron bottles received and outcome) used logistic regression with concomitant RRs and general linear models, with covariate control as applicable.Results: Of 1482 infants randomly allocated, 1276 had 9-mo data (n = 312-327/group). Iron supplementation in infancy, but not pregnancy, reduced ID risk: RRs (95% CIs) were 0.89 (0.79, 0.998) for placebo/iron compared to placebo/placebo, 0.79 (0.63, 0.98) for placebo/iron compared to iron/placebo, 0.87 (0.77, 0.98) for iron/iron compared to placebo/placebo, and 0.86 (0.77, 0.97) for iron/iron compared to iron/placebo. However, >60% of infants still had ID at 9 mo. Receiving more bottles of iron in infancy was associated with better infant iron status at 9 mo but only among iron-supplemented infants whose mothers were also iron supplemented (i.e., the iron/iron group). There were no group differences in hospitalizations or illnesses and no adverse effects on growth overall or among infants who were iron sufficient at birth.Conclusions: Iron supplementation in Chinese infants reduced ID at 9 mo without adverse effects on growth or illness. Effects of iron supplementation in pregnancy were observed only when higher amounts of iron were distributed in infancy. This trial was registered at clinicaltrials.gov as NCT00613717. [ABSTRACT FROM AUTHOR]