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381 results on '"Fornara, P"'

7. Two florigens and a florigen-like protein form a triple regulatory module at the shoot apical meristem to promote reproductive transitions in rice

Author

Giaume, Francesca, Bono, Giulia Ave, Martignago, Damiano, Miao, Yiling, Vicentini, Giulio, Toriba, Taiyo, Wang, Rui, Kong, Dali, Cerise, Martina, Chirivì, Daniele, Biancucci, Marco, Khahani, Bahman, Morandini, Piero, Tameling, Wladimir, Martinotti, Michela, Goretti, Daniela, Coupland, George, Kater, Martin, Brambilla, Vittoria, Miki, Daisuke, Kyozuka, Junko, and Fornara, Fabio

Published
2023
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8. Using Visual Social Media in Language Learning to Investigate the Role of Social Presence

Author

Fornara, Fabrizio and Lomicka, Lara

Abstract

In this paper, we attempt to investigate the pedagogical value of visual social media platforms, specifically Instagram, for the development of the online social presence of language classes. Students in intermediate university-level French and Italian classes used Instagram for a six-week period to reply to a series of questions prompted by the instructor as a way to engage in interaction with their own classmates. This research examines how students establish a community of inquiry (CoI) and investigates the development of social presence in students' posts. Using a mixed methods approach, we performed a content analysis of the transcripts of Instagram posts, coding for social presence. Given the visual nature of Instagram, we also conducted a visual analysis of representative posts to investigate the multimodal projection of social presence. Additionally, we administered voluntary pre-questionnaires to capture demographic data and students' experience with Instagram. We analyzed the data using the social presence density calculation and performed basic statistical analyses. Findings indicate that students did build online social presence, which can promote the development of a CoI. Both language groups performed in similar ways, which may be a result of the tool rather than the language and context. This finding is consistent with the general use of visual social media as a tool for self-expression, self-identity, and community building.

Published
2019
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9. A paired-kidney allocation study found superior survival with HLA-DR compatible kidney transplants in the Eurotransplant Senior Program

Author

Tieken, I., Haasnoot, G., van Meel, M., Rump, L.C., Rosenkranz, A., Horn, S., Margreiter, R., Schneeberger, S., Oberbauer, R., Pohanka, E., Függer, F., Mühlbacher, F., Berlakovich, G., Meurisse, M., Weekers, L., Ysebaert, D., Wissing, K.M., Mikhalski, D., Mourad, M., van Biesen, W., Kuypers, D., Floege, J., Anthuber, M., Viebahn, R., Schenker, P., Budde, K., Pratschke, J., Zidek, W., Melchior, S., Woitas, R., Strassburg, C.H., Hugo, C., Wirth, M., Schiffer, M., Kribben, A., Pisarski, P., Fichtner-Feigl, S., Haubitz, M., Weimer, R., Weithofer, P., Fornara, P., Fisher, L., Sester, U., Zeier, M., Kliem, V., Klempnauer, l, Grimm, M.O., Kunzendorf, U., Stippel, D., Arns, W., Mönch, C., Nitschke, M., Bartels, M., Krämer, B., Kruger, B., Heemann, U., Werner, J., Hoyer, J., Wolters, H.H., Suwelack, B., Lutz, J., Banas, B., Hakenberg, O., Olbricht, C.J., Kalus, M., Schwenger, V., Nadalin, S., Schröppel, B., Lopau, K., Seelen, M.A.J., Berger, S.P., de Fijter, J.W., van der Linden, S.J., Christiaans, M.H.L., van de Wetering, J., van Zuilen, A.D., Bemelman, F., Nurmohamed, A., Hilbrands, L., de Fijter, Johan, Dreyer, Geertje, Mallat, Marko, Budde, Klemens, Pratschke, Johann, Klempnauer, Jürgen, Zeier, Martin, Arns, Wolfgang, Hugo, Christian, Rump, Lars-Christian, Hauser, Ingeborg, Schenker, Peter, Schiffer, Mario, Grimm, Marc-Oliver, Kliem, Volker, Olbricht, Christoph J., Pisarski, Przemyslaw, Banas, Bernhard, Suwelack, Barbara, Hakenberg, Oliver, Berlakovich, Gabriela, Schneeberger, Stefan, van de Wetering, Jacqueline, Berger, Stefan, Bemelman, Frederike, Kuypers, Dirk, Heidt, Sebastiaan, Rahmel, Axel, Claas, Frans, Peeters, Patrick, Oberbauer, Rainer, Heemann, Uwe, and Krämer, Bernhard K.

Published
2023
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14. Patient-reported outcome and cognitive measures to be used in vascular and brain tumor surgery: proposal for a minimum set

Author

Schiavolin, Silvia, Mariniello, Arianna, Broggi, Morgan, Abete-Fornara, Giorgia, Bollani, Alessandra, G, Giulio Palmas, Bottini, Gabriella, Querzola, Matteo, Scarpa, Pina, Casarotti, Alessandra, De Michele, Sara, Isella, Valeria, Mauri, Ilaria, Maietti, Alessandra, Miramonti, Valentina, Orru, Maria Immacolata, Pertichetti, Marta, Pini, Elisa, Regazzoni, Rossana, Subacchi, Sara, Ferroli, Paolo, and Leonardi, Matilde

Published
2022
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21. Robotic-assisted kidney transplantation in obese recipients compared to non-obese recipients: the European experience

Author

Prudhomme, Thomas, Beauval, Jean Baptiste, Lesourd, Marine, Roumiguié, Mathieu, Decaestecker, Karel, Vignolini, Graziano, Campi, Riccardo, Serni, Sergio, Territo, Angelo, Gausa, Luis, Tugcu, Volkan, Sahin, Selcuk, Alcaraz, Antonio, Musquera, Mireia, Stockle, Michael, Janssen, Martin, Fornara, Paolo, Mohammed, Nasreldin, Del Bello, Arnaud, Kamar, Nassim, Sallusto, Federico, Breda, Alberto, and Doumerc, Nicolas

Published
2021
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33. DGN-Handlungsempfehlung (S1-Leitlinie) – PSMA-Liganden-PET/CT in der Diagnostik des Prostatakarzinoms – Stand: 01/2022 – AWMF-Registernummer: 031-055

Author

Afshar-Oromieh, A., Eiber, M., Fendler, W., Schmidt, M., Rahbar, K., Ahmadzadehfar, H., Umutlu, L., Hadaschik, B., Hakenberg, O., Fornara, P., Kurth, J., Neels, O., Wester, H.-J., Schwaiger, M., Kopka, K., Haberkorn, U., Herrmann, K., and Krause, B.

Subjects
Prostate Specific Membrane Antigen, PET/CT, Prostate Cancer, PSMA, Medizin, Radiology, Nuclear Medicine and imaging, General Medicine, Guideline, Positron Emission Tomography
Abstract

PSMA-PET/CT for imaging prostate cancer (PC) has spread worldwide since its clinical introduction in 2011. The majority of experiences have been collected for PSMA-PET-imaging of recurrent PC. Data for primary staging of high-risk PC are highly promising. Meanwhile, a plethora of PSMA-ligands are available for clinical use (e.g. 68Ga-PSMA-11, 68GaPSMA-I&T, 68Ga-PSMA-617, 18F-DCFBC, 18F-DCFPyL, 18F-PSMA-1007, 18F-rhPSMA-7 and 18F-JK-PSMA-7). However, an official approval is available only for 68Ga-PSMA-11 (approved by the US FDA in 2020) and 18F-DCFPyL (approved by the US FDA in 2021). Recommendations for acquisition times vary from 1-2h p.i. It has been shown that for the majority of tumour lesions, the contrast in PSMAPET/CT increases with time. Therefore, additional late imaging can help to clarify unclear findings. PSMA-PET/CT should be performed prior to commencing an androgen deprivation therapy (ADT) since (long term) ADT reduces the visibility of PC lesions. Following injection of PSMA-ligands, hydration and forced diuresis are recommended for PSMA-ligands with primarily excretion via the kidneys in order to increase the visibility of tumour lesions adjacent to the urinary bladder. PSMA-ligands are physiologically taken up in multiple normal organs. For some 18F-labelled PSMA-ligands, presence of unspecific focal bone uptake has been reported. When using these tracers, focal bone uptake without CT-correlate should be interpreted with great caution. Besides prostate cancer, practically all solid tumors express PSMA in their neovasculature thereby taking up PSMA-ligands, although usually at a lower extent compared to PC. Also multiple benign lesions and inflammatory processes (e.g. lymph nodes) take up PSMA-ligands, also usually at lower extent compared to PC.

Published
2023
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34. Expression of GP88 (progranulin) in serum of prostate cancer patients is associated with Gleason scores and overall survival

Author

Greither T, Fischer K, Theil G, Marcou M, Holzhausen HJ, Weigelt K, Serrero G, Hicks D, Yue BB, Fornara P, Wullich B, Taubert H, Wach S, and Lieb V

Subjects
GP88, progranulin, prostate cancer, Gleason score, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Thomas Greither,1,* Kersten Fischer,2,* Gerit Theil,2 Marios Marcou,1,2 Hans-Juergen Holzhausen,3 Katrin Weigelt,4 Ginette Serrero,5,6 David Hicks,5 Binbin Yue,5 Paolo Fornara,2 Bernd Wullich,4 Helge Taubert,4 Sven Wach,4 Verena Lieb4 1Center for Reproductive Medicine and Andrology, Martin Luther University Halle-Wittenberg, Halle, Germany; 2Department of Urology, Martin Luther University Halle-Wittenberg, Halle, Germany; 3Department of Pathology, Martin Luther University Halle-Wittenberg, Halle, Germany; 4Department of Urology and Pediatric Urology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany; 5A&G Pharmaceutical Inc., Columbia, Maryland, USA; 6Program in Oncology, University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore, Maryland, USA *These authors contributed equally to this work Background: GP88/Progranulin is a well-recognized cell growth promoter in different cancers, and elevated serum GP88 levels have been described as negative prognostic factor in breast cancer. However, serum levels in prostate cancer (PCa) patients have not yet been studied. Material and Methods: We analyzed serum GP88 levels by enzyme immunosorbent assay and correlated them with clinicopathological parameters in PCa patients. PCa patients were separated into two groups based on the serum GP88 median level (low ≤44.56 ng/mL or high >44.56 ng/mL) and according to their median age (younger ≤66 years or elder patients >66 years). Results: Low serum GP88 levels were more often detected in younger patients and high levels in elder patients (P=0.018; Fisher’s exact test). PCa patients were separated into three groups, Gleason score (GS) ≤6; GS=7; and GS≥8. In receiver operating characteristic analyses, we could distinguish GS≤6 from GS=7 [area under the curve (AUC): 0.646; P=0.018] and GS≤6 from GS≥8 (AUC: 0.629; P=0.048) but not GS=7 from GS≥8. For survival analysis, GP88 levels were separated into two groups by an optimized cutoff value of 36.92 ng/mL. Using this GP88 stratification, all PCa patients and younger patients with a low serum GP88 level had a significantly better overall survival compared with patients with higher serum GP88 levels (log-rank test P=0.010 and P=0.024). Conclusion: Serum GP88 levels are significantly different depending on age and GS, and they are associated with the prognosis of PCa patients. Keywords: GP88, progranulin, prostate cancer, Gleason score

Published
2018

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