8 results on '"Dykxhoorn J"'
Search Results
2. Temporal patterns in the recorded annual incidence of common mental disorders over two decades in the United Kingdom: a primary care cohort study.
- Author
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Dykxhoorn, J., Osborn, D., Walters, K., Kirkbride, J. B., Gnani, S., and Lazzarino, A. I.
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PSYCHIATRIC epidemiology , *RESEARCH funding , *MENTAL illness , *SEX distribution , *DESCRIPTIVE statistics , *AGE distribution , *LONGITUDINAL method , *RACE , *SOCIODEMOGRAPHIC factors , *CONFIDENCE intervals - Abstract
Background: Common mental disorders (CMDs) including depression, anxiety, and stress are very common, but it is unclear whether the last decades of social, economic, and political change have impacted incidence of CMD. This study explored temporal trends in the recorded incidence of CMD in the United Kingdom. Methods: We used data from general practices in the United Kingdom (Clinical Practice Research Datalink) to estimate the annual recorded incidence of CMD for 2000–2020, including symptoms, diagnosis, or pharmaceutical treatment. Trends were explored by sex, age, ethnicity, region, deprivation, and comorbidity. Results: We included 29 480 164 individuals who were followed up for 12.5 years on average (s.d. = 6.4 years). The recorded incidence of CMD episodes was 55.9 per 1000 person-years in 2000 [95% confidence interval (CI) 55.8–56.1], increasing to 79.6 per 1000 person-years in 2019 (95% CI 79.5–79.8). Females had higher recorded incidence rates, as did those living in more deprived areas. We observed striking patterns by age over time, with rates in ages 16–24 increasing from 40.2 per 1000 in 2000 (95% CI 39.8–40.5), to 107.8 per 1000 in 2019 (95% CI 107.0–108.6). In contrast, the rates in those aged ≥55 years decreased since 2014. There were differing patterns of incidence by ethnic group, with a steeper increase in Asian, Black, and mixed groups in recent years. Conclusions: Overall, the incidence of recorded CMD in the UK general practice increased between 2000 and 2019 with a small decrease in 2020. The overall trends obscured important differences across population subgroups, which may have implications for prevention. [ABSTRACT FROM AUTHOR]
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- 2024
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3. Association between risk of dementia and very late-onset schizophrenia-like psychosis: a Swedish population-based cohort study.
- Author
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Stafford, J., Dykxhoorn, J., Sommerlad, A., Dalman, C., Kirkbride, J. B., and Howard, R.
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DEMENTIA risk factors , *DIAGNOSIS of dementia , *CONFIDENCE intervals , *SCHIZOPHRENIA , *PSYCHOSES , *AGE distribution , *DELAYED onset of disease , *RISK assessment , *DESCRIPTIVE statistics , *LONGITUDINAL method - Abstract
Background: Although the incidence of psychotic disorders among older people is substantial, little is known about the association with subsequent dementia. We aimed to examine the rate of dementia diagnosis in individuals with very late-onset schizophrenia-like psychosis (VLOSLP) compared to those without VLOSLP. Methods: Using Swedish population register data, we established a cohort of 15 409 participants with VLOSLP matched by age and calendar period to 154 090 individuals without VLOSLP. Participants were born between 1920 and 1949 and followed from their date of first International Classification of Diseases [ICD], Revisions 8–10 (ICD-8/9/10) non-affective psychotic disorder diagnosis after age 60 years old (or the same date for matched participants) until the end of follow-up (30th December 2011), emigration, death, or first recorded ICD-8/9/10 dementia diagnosis. Results: We found a substantially higher rate of dementia in individuals with VLOSLP [hazard ratio (HR): 4.22, 95% confidence interval (95% CI) 4.05–4.41]. Median time-to-dementia-diagnosis was 75% shorter in those with VLOSLP (time ratio: 0.25, 95% CI 0.24–0.26). This association was strongest in the first year following VLOSLP diagnosis, and attenuated over time, although dementia rates remained higher in participants with VLOSLP for up to 20 years of follow-up. This association remained after accounting for potential misdiagnosis (2-year washout HR: 2.22, 95% CI 2.10–2.36), ascertainment bias (HR: 2.89, 95% CI 2.75–3.04), and differing mortality patterns between groups (subdistribution HR: 2.89, 95% CI 2.77–3.03). Conclusions: Our findings demonstrate that individuals with VLOSLP represent a high-risk group for subsequent dementia. This may be due to early prodromal changes for some individuals, highlighting the importance of ongoing symptom monitoring in people with VLOSLP. [ABSTRACT FROM AUTHOR]
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- 2023
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4. Migrant status and risk of compulsory admission at first diagnosis of psychotic disorder: a population-based cohort study in Sweden.
- Author
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Terhune, J., Dykxhoorn, J., Mackay, E., Hollander, A.-C., Kirkbride, J. B., and Dalman, C.
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IMMIGRANTS , *BIRTHPLACES , *POPULATION density , *CONFIDENCE intervals , *PSYCHOSES , *RISK assessment , *HOSPITAL care , *DESCRIPTIVE statistics , *LOGISTIC regression analysis , *ODDS ratio , *ETHNIC groups , *HEALTH equity - Abstract
Background: Minority ethnic and migrant groups face an elevated risk of compulsory admission for mental illness. There are overlapping cultural, socio-demographic, and structural explanations for this risk that require further investigation. Methods: By linking Swedish national register data, we established a cohort of persons first diagnosed with a psychotic disorder between 2001 and 2016. We used multilevel mixed-effects logistic modelling to investigate variation in compulsory admission at first diagnosis of psychosis across migrant and Swedish-born groups with individual and neighbourhood-level covariates. Results: Our cohort included 12 000 individuals, with 1298 (10.8%) admitted compulsorily. In an unadjusted model, being a migrant [odds ratio (OR) 1.48; 95% confidence interval (CI) 1.26–1.73] or child of a migrant (OR 1.27; 95% CI 1.10–1.47) increased risk of compulsory admission. However after multivariable modelling, region-of-origin provided a better fit to the data than migrant status; excess risk of compulsory admission was elevated for individuals from sub-Saharan African (OR 1.94; 95% CI 1.51–2.49), Middle Eastern and North African (OR 1.46; 95% CI 1.17–1.81), non-Nordic European (OR 1.27; 95% CI 1.01–1.61), and mixed Swedish-Nordic backgrounds (OR 1.33; 95% CI 1.03–1.72). Risk of compulsory admission was greater in more densely populated neighbourhoods [OR per standard deviation (s.d.) increase in the exposure: 1.12, 95% CI 1.06–1.18], an effect that appeared to be driven by own-region migrant density (OR per s.d. increase in exposure: 1.12; 95% CI 1.02–1.24). Conclusions: Inequalities in the risk of compulsory admission by migrant status, region-of-origin, urban living and own-region migrant density highlight discernible factors which raise barriers to equitable care and provide potential targets for intervention. [ABSTRACT FROM AUTHOR]
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- 2022
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5. Community interventions for improving adult mental health: mapping local policy and practice in England.
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Duncan, F., Baskin, C., McGrath, M., Coker, J. F., Lee, C., Dykxhoorn, J., Adams, E. A., Gnani, S., Lafortune, L., Kirkbride, J. B., Kaner, E., Jones, O., Samuel, G., Walters, K., Osborn, D., and Oliver, E. J.
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MENTAL health ,COMMUNITIES ,HEALTH policy ,WELL-being ,PUBLIC health ,RESEARCH ,RESEARCH methodology ,MEDICAL cooperation ,EVALUATION research ,COMPARATIVE studies ,EXERCISE ,HEALTH promotion - Abstract
Background: Public mental health (PMH) aims to improve wellbeing and prevent poor mental health at the population level. It is a global challenge and a UK priority area for action. Communities play an important role in the provision of PMH interventions. However, the evidence base concerning community-based PMH interventions is limited, meaning it is challenging to compare service provision to need. Without this, the efficient and equitable provision of services is hindered. Here, we sought to map the current range of community-based interventions for improving mental health and wellbeing currently provided in England to inform priority areas for policy and service intervention.Method: We adopted an established mapping exercise methodology, comparing service provision with demographic and deprivation statistics. Five local authority areas of England were selected based on differing demographics, mental health needs and wider challenging circumstances (i.e. high deprivation). Community-based interventions were identified through: 1) desk-based research 2) established professional networks 3) chain-referral sampling of individuals involved in local mental health promotion and prevention and 4) peer researchers' insight. We included all community-based, non-clinical interventions aimed at adult residents operating between July 2019 and May 2020.Results: 407 interventions were identified across the five areas addressing 16 risk/protective factors for PMH. Interventions for social isolation and loneliness were most prevalent, most commonly through social activities and/or befriending services. The most common subpopulations targeted were older adults and people from minority ethnic backgrounds. Interventions focusing on broader structural and environmental determinants were uncommon. There was some evidence of service provision being tailored to local need, though this was inconsistent, meaning some at-risk groups such as men or LGBTQ+ people from minority ethnic backgrounds were missed. Interventions were not consistently evaluated.Conclusions: There was evidence of partial responsiveness to national and local prioritising. Provision was geared mainly towards addressing social and individual determinants of PMH, suggesting more integration is needed to engage wider service providers and policy-makers in PMH strategy and delivery at the community level. The lack of comprehensive evaluation of services to improve PMH needs to be urgently addressed to determine the extent of their effectiveness in communities they serve. [ABSTRACT FROM AUTHOR]- Published
- 2021
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6. Under-diagnosis of mood disorders in Canada.
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Pelletier, L., O'Donnell, S., Dykxhoorn, J., McRae, L., and Patten, S. B.
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- 2017
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7. Monitoring positive mental health and its determinants in Canada: the development of the Positive Mental Health Surveillance Indicator Framework.
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Orpana, H., Vachon, J., Dykxhoorn, J., McRae, L., and Jayaraman, G.
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MENTAL health ,PUBLIC health surveillance ,HEALTH status indicators ,CANADA. Public Health Agency - Abstract
Introduction: The Mental Health Strategy for Canada identified a need to enhance the collection of data on mental health in Canada. While surveillance systems on mental illness have been established, a data gap for monitoring positive mental health and its determinants was identified. The goal of this project was to develop a Positive Mental Health Surveillance Indicator Framework, to provide a picture of the state of positive mental health and its determinants in Canada. Data from this surveillance framework will be used to inform programs and policies to improve the mental health of Canadians. Methods: A literature review and environmental scan were conducted to provide the theoretical base for the framework, and to identify potential positive mental health outcomes and risk and protective factors. The Public Health Agency of Canada's definition of positive mental health was adopted as the conceptual basis for the outcomes of this framework. After identifying a comprehensive list of risk and protective factors, mental health experts, other governmental partners and non-governmental stakeholders were consulted to prioritize these indicators. Subsequently, these groups were consulted to identify the most promising measurement approaches for each indicator. Results: A conceptual framework for surveillance of positive mental health and its determinants has been developed to contain 5 outcome indicators and 25 determinant indicators organized within 4 domains at the individual, family, community and societal level. This indicator framework addresses a data gap identified in Canada's strategy for mental health and will be used to inform programs and policies to improve the mental health status of Canadians throughout the life course. [ABSTRACT FROM AUTHOR]
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- 2016
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8. Mapping the delivery of community-based public mental health interventions in diverse areas of England: emerging promising practice.
- Author
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Duncan, F., Mcgrath, M., Baskin, C., Zijlstra, G., Oliver, E., Osborn, D., Gnani, S., Dykxhoorn, J., Kaner, E., Kirkbride, J., Lafortune, L., Lee, C., and Walters, K.
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UNEMPLOYMENT ,MENTAL health ,PUBLIC health ,MENTAL illness ,MEDICAL personnel ,MENTAL health promotion - Abstract
Introduction: Public Mental Health (PMH) is a UK priority and a challenge for public health practitioners globally. However, strengthening the evidence base regarding community level interventions to help prevent mental health problems from arising is a priority for practitioners. Objectives: 1) to identify the types of community-based interventions employed in purposively selected diverse geographical areas of England to improve PMH outcomes and 2) to determine the model, target population and content of each intervention, as well as its suitability for larger scale evaluation. Methods: A number of case study local authority areas across English regions (population size ranged from 136000 to 648200) were chosen. Community-based interventions were identified through: (i) desk-based data capture from standardised searches of publicly-available information (e.g., policy, strategy, intervention advertising), (ii) through established professional networks and service contacts such as at local authorities, and (iii) by chainreferral sampling of individuals involved in local PMH promotion. Results: A range of innovative public mental health interventions are in place across England. These include both universal interventions and those targeted at at-risk groups. Principle domains of focus were general wellbeing (e.g. stress relief and confidence building courses, mindfulness and meditation classes, activity groups and community cafes to prevent social isolation), healthy lifestyles (e.g. walking groups), unemployment/job security (e.g. programmes delivered in partnership with local services to support local longterm unemployed) and financial health (e.g. debt advice services). Conclusions: The number and variety of community-based PMH interventions emerging across England is very promising. The interventions with the most potential will be discussed further. [ABSTRACT FROM AUTHOR]
- Published
- 2020
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