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3. Renaissance and Baroque Europe

Author

Bambach, Carmen C., Campbell, Thomas, Draper, James David, Bambach, Carmen C., Orenstein, Nadine M., Libin, Laurence, Pyhrr, Stuart W., Christiansen, Keith, Draper, James David, Liedtke, Walter, Stein, Perrin, Vincent, Clare, and Rieder, William

Published
1999
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4. Respiratory Phenomics across Multiple Models of Protein Hyperacylation in Cardiac Mitochondria Reveals a Marginal Impact on Bioenergetics

Author

Fisher-Wellman, Kelsey H., Draper, James A., Davidson, Michael T., Williams, Ashley S., Narowski, Tara M., Slentz, Dorothy H., Ilkayeva, Olga R., Stevens, Robert D., Wagner, Gregory R., Najjar, Rami, Hirschey, Mathew D., Thompson, J. Will, Olson, David P., Kelly, Daniel P., Koves, Timothy R., Grimsrud, Paul A., and Muoio, Deborah M.

Published
2019
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6. Europe 1700-1900

Author

Koeppe, Wolfram, Baetjer, Katharine, Munger, Jeffrey H., Draper, James David, Stein, Perrin, Barker, Elizabeth E., Bolton, Andrew, Tinterow, Gary, Plomp, Michiel C., and Ives, Colta

Published
2003
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7. Europe 1700-1900

Author

Baetjer, Katharine, Koeppe, Wolfram, Hecht, Johanna, Munger, Jeffrey H., Draper, James David, Tinterow, Gary, Ives, Colta, Heyde, Herbert, Daniel, Malcolm, and Stein, Susan Alyson

Published
2002
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11. Europe 1700-1900

Author

Kisluk-Grosheide, Daniëlle O., Munger, Jeffrey H., Koeppe, Wolfram, Baker, Elizabeth E., Draper, James David, Tinterow, Gary, Pollen, Stewart S., Daniel, Malcolm, McNab, Jessie, Ives, Colta, Stein, Susan Alyson, Heyde, Herbert, and Rewald, Sabine

Published
2001
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12. Renaissance and Baroque Europe

Author

de Jésus, Mary Sprinson, Bambach, Carmen C., Plomp, Michiel C., Orenstein, Nadine M., Stein, Perrin, Pyhrr, Stuart W., Christiansen, Keith, Liedtke, Walter, Baker, Elizabeth E., and Draper, James David

Published
2001
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13. Europe 1700 - 1900

Author

Rieder, William, Phyrr, Stuart W., Stein, Perrin, Ives, Colta, Tinterow, Gary, Rewald, Sabine, Daniel, Malcolm, Koeppe, Wolfram, Heyde, Herbert, Draper, James David, McNab, Jessie, and Le Corbeiller, Clare

Published
2000
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16. Renaissance and Baroque Europe

Author

Bambach, Carmen C., Orenstein, Nadine M., Draper, James David, Logan, Carolyn, Christiansen, Keith, Liedtke, Walter, Phyrr, Stuart W., and Stein, Perrin

Published
1998
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17. Europe 1700-1900

Author

Stein, Perrin, Hecht, Johanna, Koeppe, Wolfram, Pyhrr, Stuart W., Libin, Laurence, Le Corbeiller, Clare, McNab, Jessie, Loveman, Jennifer A., Draper, James David, Nudel, Marina, Tinterow, Gary, Daniel, Malcolm, Hambourg, Maria Morris, Ives, Colta, and Stein, Susan Alyson

Published
1998
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23. The Metamorphoses of 'Andragogy.'

Author

Draper, James A.

Abstract

Traces the origin and early usage of the term andragogy in the 19th and 20th centuries. Reviews the andragogy debate and the viability of the theory. Concludes with reflections on the search for identity in the field of adult education. (SK)

Published
1998

24. Selected Chronology of Adult Education in Canada.

Author

Draper, James A. and Carere, Jane

Abstract

Provides annotated descriptions of events in adult education in English-speaking Canada from 1800 to 1990. Includes a preface by Michael Welton, an introduction describing the methodology by James A. Draper, 28 references, and 29 additional readings. (SK)

Published
1998

25. Using the Chick Embryo Model to Examine the Effects of Hypoxia Pre-conditioning of Uveal Melanoma Cells on Tumor Growth and Metastasis.

Author

Draper, James, Alexander, Jodi, Nair, Rohini M., Scullion, Nicole, Narayana, Revu V. L., Aughton, Karen, Herrmann, Anne, Vemuganti, Geeta K., Kalirai, Helen, and Coupland, Sarah E.

Subjects
*CHICKEN embryos, *UVEA cancer, *TUMOR growth, *CELL growth, *METASTASIS, *HYPOXEMIA
Abstract

Highly dynamic oxygen gradients occur within tumors that can result in a hypoxic response, contributing to tumor progression and metastasis. Evidence in uveal melanoma (UM) suggests an upregulated hypoxia response in some poor prognosis UM characterized by HIF1α signaling. We aimed to investigate the effects of exposure to hypoxia on tumor growth and dissemination in the chick embryo chorioallantoic membrane (CAM) model. UM cell lines (MP41, 92.1, MP46, and OMM1) were grown in two-dimensional culture and pre-exposed to hypoxic (1% O2) conditions for 72 h. The effects of this hypoxia pre-conditioning on cell number and clonogenicity as compared with 21% O2 ("normoxia") were investigated prior to transplantation of the cells onto the CAM. Nodule-forming efficiency (NFE), nodule size, and the presence/absence of tumor cell dissemination were determined macroscopically and histologically. Exposure of UM cell lines to hypoxia upregulated HIF1α expression compared to cells cultured in normoxia. A 72-h pre-exposure to hypoxia significantly reduced cell number and clonogenicity in the MP41 and OMM1 cell lines while it had little effect in 92.1 and MP46 cells. When 72-h hypoxia pre-conditioned cells were grown in three-dimensions on the CAM, a reduction in NFE and nodule size was observed when compared with normoxic UM cells. All nodules were composed of proliferating (Ki-67+) Melan-A + cells and displayed chick blood vessel recruitment. Spread of UM cells into the adjacent CAM was observed; however, dissemination to the chick liver was only seen with 92.1 cells grown under normoxia. Hypoxia pre-conditioning does not appear to drive a metastatic phenotype in UM; however, further understanding of how oxygen dynamics within the tumor microenvironment regulates HIF1 signaling is needed to determine whether inhibitors of HIF signaling represent a therapeutic option in metastatic UM. [ABSTRACT FROM AUTHOR]

Published
2023
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26. The Dynamic Mandala of Adult Education.

Author

Draper, James A.

Abstract

Outlines basic assumptions and principles underlying adult education and describes today's challenges: maintaining democracy, technological changes, explosion of information, global competition/cooperation, environment, and universal human rights. Advocates a holistic world view of adult education. (SK)

Published
1992

44. Europe 1700-1900

Author

Raggio, Olga, Tinterow, Garry, Ives, Colta, McNab, Jessie, Libin, Laurence, LeCorbeiller, Clare, Fahy, Everett, Draper, James David, Daniel, Malcolm, and Loveman, Jennifer A.

Published
1995
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48. Renaissance Europe

Author

Pyhrr, Stuart W., Griswold, William M., Christiansen, Keith, Wrightsman, Jayne, Liedtke, Walter, Bayer, Andrea, Draper, James David, McNab, Jessie, Zrebiec, Alice, Boorsch, Suzanne, and Wyckoff, Elizabeth

Published
1992
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49. Europe 1700-1900

Author

Mules, Helen B., Draper, James David, Le Corbeiller, Clare, Parker, James, Reider, William, Vincent, Clare, Baetjer, Katherine, Tinterow, Gary, Ives, Colta, Daniel, Malcolm, Rose, Frederick P., and Golthorpe, Caroline

Published
1992
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50. Europe 1700-1900

Author

Majer, Michele M., Raggio, Olga, Le Corbeiller, Clare, McNab, Jessie, Libin, Laurence, Pyhrr, Stuart W., Rieder, William, Daniel, Malcolm, Heckscher, Morrison H., Ives, Colta, Draper, James David, Tinterow, Gary, and Mules, Helen B.

Published
1993
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