39 results on '"Deri, Norma"'
Search Results
2. Incidence of SARS-CoV-2 infection in patients with multiple sclerosis who received SARS-CoV-2 vaccines and are under treatment with high-efficacy therapies in Argentina
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Carnero Contentti, Edgar, López, Pablo A., Pappolla, Agustín, Alonso, Ricardo, Silva, Berenice, Deri, Norma, Balbuena, María E., Burgos, Marcos, Luetic, Geraldine, Alvez Pinheiro, Amelia, Cabrera, Mariela, Hryb, Javier, Nofal, Pedro, Pestchanker, Claudia, Vrech, Carlos, Tavolini, Darío, Tkachuk, Verónica, Zanga, Gisela, Marrodan, Mariano, Ysrraelit, María Célica, Correale, Jorge, Carrá, Adriana, Federico, Belén, Garcea, Orlando, Fernandez Liguori, Nora, Patrucco, Liliana, Cristiano, Edgardo, Giunta, Diego, Alonso Serena, Marina, and Rojas, Juan I.
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- 2024
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3. Treatment strategies and responses for attacks of neuromyelitis optica spectrum disorder: A real-world retrospective cohort study
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Carnero Contentti, Edgar, Lopez, Pablo A., Pettinicchi, Juan Pablo, Miguez, Jimena, Patrucco, Liliana, Cristiano, Edgardo, Liwacki, Susana, Tkachuk, Verónica, Balbuena, María E., Vrech, Carlos, Deri, Norma, Correale, Jorge, Marrodan, Mariano, Ysrraelit, María C., Leguizamon, Felisa, Luetic, Geraldine, Tavolini, Darío, Mainella, Carolina, Zanga, Gisela, Burgos, Marcos, Hryb, Javier, Barboza, Andrés, Lazaro, Luciana, Alonso, Ricardo, Fernández Liguori, Nora, Nadur, Débora, Alonso Serena, Marina, Caride, Alejandro, and Rojas, Juan I.
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- 2024
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4. Selection of disease modifying therapies in multiple sclerosis based on patient's age and disease activity: Data from a nationwide registry
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Piedrabuena, Maria A., Correale, Jorge, Fiol, Marcela, Marrodan, Mariano, Rojas, Juan I., Alonso, Marina, Pappolla, Agustín, Miguez, Jimena, Patrucco, Liliana, Cristiano, Edgardo, Vrech, Carlos, Cohen, Leila, Alonso, Ricardo, Silva, Berenice, Luetic, Geraldine, Deri, Norma, Burgos, Marcos, Liwacki, Susana, Piedrabuena, Raul, Tkachuk, Verónica, Barboza, Andres, Martinez, Alejandra, Balbuena, Maria E., Pinheiro, Amelia Alves, Nofal, Pedro, Lopez, Pablo A., Tavolini, Dario, Leguizamon, Felisa, Hryb, Javier P., Tizio, Santiago, Recchia, Luciano, Reich, Edgardo, Contentti, Edgar Carnero, Marcilla, Marcela Parada, Pagani, Fatima, Cabrera, Lorena M., Curbelo, Maria C., Mainella, Carolina, Liguori, Nora Fernández, Coppola, Mariano, Pettinicchi, Juan P., Carra, Adriana, Jose, Gustavo, Nadur, Debora, Bestoso, Santiago, Pestchanker, Claudia, Vazquez, Guido D., Martinez, Carlos M., and Ysrraelit, María C.
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- 2024
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5. Evaluation of the use of high-efficacy treatments (HETs) in patients with relapsing-remitting multiple sclerosis in Argentina
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Alonso, Ricardo, Casas, Magdalena, Lazaro, Luciana, Liguori, Nora Fernandez, Pita, Cecilia, Cohen, Leila, Rojas, Juan Ignacio, Pappolla, Agustín, Patrucco, Liliana, Cristiano, Edgardo, Burgos, Marcos, Vrech, Carlos, Piedrabuena, Raul, Pablo, Lopez, Deri, Norma, Luetic, Geraldine, Miguez, Jimena, Cabrera, Mariela, Martinez, Alejandra, Zanga, Gisela, Tkachuk, Verónica, Tizio, Santiago, Carnero Contentti, Edgar, Knorre, Eduardo, Leguizamon, Felisa, Mainella, Carolina, Nofal, Pedro, Liwacki, Susana, Hryb, Javier, Menichini, Maria, Pestchanker, Claudia, Garcea, Orlando, and Silva, Berenice
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- 2023
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6. Disability outcomes in NMOSD and MOGAD patients: data from a nationwide registry in Argentina
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Rojas, Juan I., Pappolla, Agustín, Patrucco, Liliana, Cristiano, Edgardo, Miguez, Jimena, Liwacki, Susana, Tkachuk, Verónica, Balbuena, María E., Vrech, Carlos, Deri, Norma, Correale, Jorge, Marrodan, Mariano, Ysrraelit, María C., Fiol, Marcela, Leguizamon, Felisa, Luetic, Geraldine, Menichini, María L., Lopez, Pablo A., Pettinicchi, Juan Pablo, Criniti, Juan, Caride, Alejandro, Tavolini, Darío, Mainella, Carolina, Zanga, Gisela, Burgos, Marcos, Hryb, Javier, Barboza, Andrés, Lazaro, Luciana, Alonso, Ricardo, Silva, Berenice, Fernández Liguori, Nora, Nadur, Débora, Chercoff, Aníbal, Martinez, Alejandra, Steinberg, Judith, Garcea, Orlando, Carrá, Adriana, Alonso Serena, Marina, and Carnero Contentti, Edgar
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- 2023
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7. Guía de práctica clínica: tratamiento agudo de las enfermedades inflamatorio-desmielinizantes del sistema nervioso central: esclerosis múltiple, espectro de la neuromielitis óptica, encefalomielitis diseminada aguda, enfermedades asociadas a anticuerpos antiglicoproteína de la membrana del oligodendrocito, mielitis aguda y neuritis óptica. Elaborada por el Grupo de Trabajo de Enfermedades Desmielinizantes. Sociedad Neurológica Argentina
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Hryb, Javier P., Tavolini, Darío, Pagani Cassará, Fátima, Silva, Berenice, Rojas, Juan Ignacio, Sinay, Vladimiro, Tkachuk, Verónica, Alonso, Ricardo, Carnero Contentti, Edgar, Ysrraelit, María Célica, Cohen, Leila, Rotta Escalante, Roberto, Mainella, Carolina, Martínez, Alejandra Diana, Liwacki, Susana, Luetic, Geraldine, Bestoso, Santiago, Vázquez, Guido, Piedrabuena, Raúl, Vrech, Carlos, Burgos, Marcos, Tizio, Santiago, Pappolla, Agustín, Alves Pinheiro, Amelia, Giachello, Susana, Bauer, Johana, Manin, Analisa, Deri, Norma, Pérez, Celia, Camerlingo, Sebastián, Cabrera, Lorena Mariela, López, Pablo A., Zanga, Gisela, Steinberg, Judith Diana, Miguez, Jimena, Jacobo, Miguel, Casas, Magdalena, Lazaro, Luciana Grimanesa, Isa, Santiago, Menichini, María Laura, Pita, Cecilia, Laffue, Alfredo, Vila, María Celia González, and Barboza, Andrés G.
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- 2023
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8. Incidence of COVID-19 after vaccination in people with multiple sclerosis in Argentina: Data from the nationwide registry RelevarEM
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Rojas, Juan I., Luetic, Geraldine G., Vrech, Carlos, Pappolla, Agustín, Patrucco, Liliana, Cristiano, Edgardo, Marrodan, Mariano, Ysrraelit, María C., Fiol, Marcela, Correale, Jorge, Cohen, Leila, Alonso, Ricardo, Silva, Berenice, Casas, Magdalena, Garcea, Orlando, Deri, Norma, Burgos, Marcos, Liwacki, Susana, Tkachuk, Verónica, Barboza, Andres, Piedrabuena, Raúl, Blaya, Patricio, Steinberg, Judith, Martínez, Alejandra, Carra, Adriana, Tavolini, Darío, López, Pablo, Knorre, Eduardo, Nofal, Pedro, Carnero Contentti, Edgar, Alves Pinheiro, Amelia, Leguizamon, Felisa, Silva, Emanuel, Hryb, Javier, Balbuena, María Eugenia, Zanga, Gisela, Kohler, Matías, Lazaro, Luciana, Tizio, Santiago, Mainella, Carolina, Blanche, Jorge, Parada Marcilla, Marcela, Fracaro, María Eugenia, Menichini, María Laura, Sgrilli, Gustavo, Divi, Pablo, Jacobo, Miguel, Cabrera, Mariela, Míguez, Jimena, Fernandez Liguori, Nora, Viglione, Juan Pablo, Nadur, Debora, Alonso Serena, Marina, and Nuñez, Sebastián
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- 2022
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9. Guía de práctica clínica: tratamiento sintomático de esclerosis múltiple. Grupo de Trabajo de Enfermedades Desmielinizantes. Sociedad Neurológica Argentina
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Barboza, Andrés G., Sinay, Vladimiro, Zanga, Gisela, Alonso, Ricardo, Silva, Berenice, Saladino, María Laura, Cohen, Leila, Luetic, Geraldine G., Camerlingo, Sebastián, Ysrraelit, María Célica, Tenembaun, Silvia N., Tarulla, Adriana, Carnero Contentti, Edgar, López, Pablo A., Pita, Cecilia, Tavolini, Darío, Steinberg, Judith, Menichini, María Laura, Rojas, Juan I., Tizio, Santiago, Tkachuk, Verónica, González, Fernando Adrián, Martínez, Alejandra, Laffue, Alfredo, Pagani Cassara, Fátima, Piedrabuena, Raúl, Pérez, Celia, Fernández Liguori, Nora, Eizaguirre, María Bárbara, Patrucco, Liliana, Deri, Norma Haydee, Hryb, Javier, and Mellinger, Surai
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- 2022
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10. Evaluation of the times of disability progression and related factors in patients with primary progressive multiple sclerosis from Argentina
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Alonso, Ricardo, Garcea, Orlando, Rojas, Juan Ignacio, Alonso, Marina, Lázaro, Luciana, López, Pablo, Casas, Magdalena, Tkachuk, Verónica, Steinberg, Judith, Barboza, Andrés, Martínez, Alejandra, Ysrraelit, Célica, Correale, Jorge, Marrodan, Mariano, Chertcoff, Aníbal, Deri, Norma, Miguez, Jimena, Patrucco, Liliana, Cristiano, Edgardo, Pestchanker, Claudia, Silva, Emanuel, Vrech, Carlos, Zanga, Gisela, Leguizamón, Felisa, Carnero Contentti, Edgar, Carra, Adriana, Mainella, Carolina, and Silva, Berenice Anabel
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- 2022
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11. Seasonal variation in attacks of neuromyelitis optica spectrum disorders and multiple sclerosis: Evaluation of 794 attacks from a nationwide registry in Argentina
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Carnero Contentti, Edgar, Lopez, Pablo A., Pettinicchi, Juan Pablo, Criniti, Juan, Pappolla, Agustín, Miguez, Jimena, Patrucco, Liliana, Cristiano, Edgardo, Liwacki, Susana, Tkachuk, Verónica, Balbuena, María E., Vrech, Carlos, Deri, Norma, Correale, Jorge, Marrodan, Mariano, Ysrraelit, María C., Leguizamon, Felisa, Luetic, Geraldine, Menichini, María L., Tavolini, Darío, Mainella, Carolina, Zanga, Gisela, Burgos, Marcos, Hryb, Javier, Barboza, Andrés, Lazaro, Luciana, Alonso, Ricardo, Fernández Liguori, Nora, Nadur, Débora, Chercoff, Aníbal, Alonso Serena, Marina, Caride, Alejandro, Paul, Friedemann, and Rojas, Juan I.
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- 2022
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12. Clinical and demographic characteristics of male MS patients included in the national registry-RelevarEM. Does sex or phenotype make the difference in the association with poor prognosis?
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Luetic, Geraldine G., Menichini, María Laura, Vrech, Carlos, Pappolla, Agustín, Patrucco, Liliana, Cristiano, Edgardo, Marrodán, Mariano, Ysrraelit, María C., Fiol, Marcela, Correale, Jorge, Cohen, Leila, Alonso, Ricardo, Silva, Berenice, Casas, Magdalena, Garcea, Orlando, Deri, Norma, Burgos, Marcos, Liwacki, Susana, Tkachuk, Verónica, Barboza, Andrés, Piedrabuena, Raúl, Blaya, Patricio, Steinberg, Judith, Martínez, Alejandra, Carrá, Adriana, Tavolini, Darío, López, Pablo, Knorre, Eduardo, Nofal, Pedro, Volman, Gabriel, Carnero Contentti, Edgar, Pinheiro, Amelia Alves, Leguizamon, Felisa, Silva, Emanuel, Hryb, Javier, Balbuena, María Eugenia, Zanga, Gisela, Kohler, Matías, Chertcoff, Aníbal, Lazaro, Luciana, Tizio, Santiago, Mainela, Carolina, Reich, Edgardo, Recchia, Luciano, Blanche, Jorge, Marcilla, Marcela Parada, Fracaro, María Eugenia, Sgrilli, Gustavo, Divi, Pablo, Jacobo, Miguel, Cabrera, Mariela, Pagani Cassara, Fátima, Sinay, Vladimiro, Curbelo, Celeste, Míguez, Jimena, Coppola, Mariano, Liguori, Nora Fernández, Martos, Iván, Pettinicchi, Juan Pablo, Viglione, Juan Pablo, José, Gustavo, Bestoso, Santiago, Manzi, Rubén, Vázquez, Guido, Nadur, Débora, Martínez, Carlos, Serena, Marina Alonso, and Rojas, Juan I.
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- 2022
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13. Aggressive multiple sclerosis in Argentina: Data from the nationwide registry RelevarEM
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Kohler, Matías, Kohler, Eduardo, Vrech, Carlos, Pappolla, Agustín, Miguez, Jimena, Patrucco, Liliana, Correale, Jorge, Marrodan, Mariano, Gaitán, María I., Fiol, Marcela, Negrotto, Laura, Ysrraelit, María C., Cristiano, Edgardo, Carrá, Adriana, Steinberg, Judith, Martinez, Alejandra D., Curbelo, María C., Cohen, Leila, Alonso, Ricardo, Garcea, Orlando, Pita, Cecilia, Silva, Berenice, Luetic, Geraldine, Deri, Norma, Balbuena, Maria E., Tkachuk, Verónica, Carnero Contentti, Edgar, Lopez, Pablo A., Pettinicchi, Juan P., Caride, Alejandro, Burgos, Marcos, Leguizamon, Felisa, Knorre, Eduardo, Piedrabuena, Raúl, Barboza, Andrés, Liwacki, Susana, Nofal, Pedro, Volman, Gabriel, Alvez Pinheiro, Amelia, Hryb, Javier, Tavolini, Dario, Blaya, Patricio, Recchia, Luciano, Mainella, Carolina, Silva, Emanuel, Blanche, Jorge, Tizio, Santiago, Saladino, Maria L., Caceres, Fernando, Fernandez Liguori, Nora, Lazaro, Luciana, Zanga, Gisela, Parada Marcilla, Marcela, Fracaro, Maria E., Pagani Cassara, Fatima, Vazquez, Guido, Sinay, Vladimiro, Sgrilli, Gustavo, Divi, Pablo, Jacobo, Miguel, Reich, Edgardo, Cabrera, Lorena M., Menichini, María L., Coppola, Mariano, Martos, Ivan, Viglione, Juan P., Jose, Gustavo, Bestoso, Santiago, Manzi, Ruben, Giunta, Diego, Doldan, Maria.L., Alonso Serena, Marina, and Rojas, Juan I.
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- 2021
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14. COVID-19 in multiple sclerosis and neuromyelitis optica spectrum disorder patients in Latin America: COVID-19 in MS and NMOSD patients in LATAM
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Alonso, Ricardo, Silva, Berenice, Garcea, Orlando, Diaz, Patricio E. Correa, dos Passos, Giordani Rodrigues, Navarro, Deyanira A. Ramirez, Valle, Luis A. Garcia, Salinas, Luis C. Rodriguez, Negrotto, Laura, Luetic, Geraldine, Tkachuk, Verónica A., Míguez, Jimena, de Bedoya, Fernando Hamuy Diaz, Goiry, Lorna Galleguillos, Sánchez, Nicia E. Ramírez, Burgos, Marcos, Steinberg, Judith, Balbuena, Maria E., Alvarez, Priscilla Monterrey, López, Pablo A., Ysrraelit, María C., León, Rosalba A., Cohen, Aron Benzadon, Gracia, Fernando, Molina, Omaira, Casas, Magdalena, Deri, Norma H., Pappolla, Agustín, Patrucco, Liliana, Cristiano, Edgardo, Tavolini, Dario, Nadur, Debora, Granda, Ana M. Toral, Weiser, Roberto, Cassará, Fátima Pagani, Sinay, Vladimiro, Rodríguez, Claudia Cárcamo, Lazaro, Luciana G., Menichini, María L., Piedrabuena, Raúl, Escobar, Geraldine Orozco, Carrá, Adriana, Chertcoff, Anibal, Pujols, Biany Santos, Vrech, Carlos, Tarulla, Adriana, Carvajal, René, Mainella, Carolina, Becker, Jefferson, Peeters, Liesbet M., Walton, Clare, Serena, Marina Alonso, Nuñez, Sebastián, and Rojas, Juan I.
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- 2021
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15. What percentage of AQP4-ab-negative NMOSD patients are MOG-ab positive? A study from the Argentinean multiple sclerosis registry (RelevarEM)
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Carnero Contentti, Edgar, Lopez, Pablo A., Pettinicchi, Juan Pablo, Pappolla, Agustín, Miguez, Jimena, Patrucco, Liliana, Cristiano, Edgardo, Vrech, Carlos, Tkachuk, Verónica, Liwacki, Susana, Correale, Jorge, Marrodan, Mariano, Gaitán, María I., Fiol, Marcela, Negrotto, Laura, Ysrraelit, María C., Burgos, Marcos, Leguizamon, Felisa, Tavolini, Dario, Deri, Norma, Balbuena, Maria E., Mainella, Carolina, Luetic, Geraldine, Blaya, Patricio, Hryb, Javier, Menichini, María L., Alvez Pinheiro, Amelia, Nofal, Pedro, Zanga, Gisela, Barboza, Andrés, Martos, Ivan, Lazaro, Luciana, Alonso, Ricardo, Silva, Emanuel, Bestoso, Santiago, Fracaro, Maria E., Carrá, Adriana, Garcea, Orlando, Fernandez Liguori, Nora, Alonso Serena, Marina, Caride, Alejandro, and Rojas, Juan I.
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- 2021
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16. Usage trend of oral drugs for multiple sclerosis patients in Argentina
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Alonso, Ricardo, Garcea, Orlando, Eizaguirre, María Barbara, Man, Federico, Bizzo, Abril Lopez, Cohen, Leila, Rojas, Juan I, Patrucco, Liliana, Cristiano, Edgardo, Pita, Cecilia, Tkachuk, Veronica, Balbuena, Maria Eugenia, Carnero Contentti, Edgar, Lopez, Pablo, Pettinichi, Juan Pablo, Deri, Norma, Miguez, Jimena, Pappolla, Agustín, Lazaro, Luciana, Liguori, Nora Fernadez, Correale, Jorge, Carrá, Adriana, and Silva, Berenice A
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- 2021
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17. High birth weight and risk of multiple sclerosis: A multicentre study in Argentina
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Luetic, Geraldine G., Menichini, Maria L., Deri, Norma, Steinberg, Judith, Carrá, Adriana, Cristiano, Edgardo, Patrucco, Liliana, Curbelo, Maria C., and Rojas, Juan I.
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- 2021
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18. Guías de práctica para indicación y contraindicaciones de vacunación de pacientes con esclerosis múltiple
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Barboza, Andrés G., Sinay, Vladimiro, Silva, Berenice Anabel, Rojas, Juan I., Ysrraelit, María Célica, Carnero Contentti, Edgar, Negrotto, Laura, Tavolini, Darío, Deri, Norma, Tizio, Santiago, Gaitán, María Inés, Luetic, Geraldine, Patrucco, Liliana, Martínez, Alejandra D., Parada Marcilla, Marcela, Hryb, Javier, Alonso, Ricardo, Bestoso, Santiago, Cabrera, Lorena M., Cristiano, Edgardo, Jacobo, Miguel, Liwacki, Susana, Lopez, Pablo A., Mainella, Carolina, Menichini, María Laura, Miguez, Jimena, Pagani Cassara, Fatima, Pérez, Celia, Piedrabuena, Raúl, Rotta Escalante, Roberto, Steinberg, Judith, Tkachuk, Veronica Analia, Alejandro Vrech, Carlos, and Zanga, Gisela
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- 2021
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19. Do immunosuppressive treatments influence immune responses against adenovirusbased COVID-19 vaccines in patients with multiple sclerosis? An Argentine multicenter study.
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Silva, Berenice Anabel, Miglietta, Esteban, Casabona, Juan Cruz, Wenker, Shirley, Eizaguirre, María Bárbara, Alonso, Ricardo, Casas, Magdalena, Lázaro, Luciana Grimanesa, Man, Federico, Portuondo, Gustavo, Bisso, Abril Lopez, Zavala, Noelia, Casales, Federico, Imhoff, Gastón, Steinberg, Dra Judith, López, Pablo Adrián, Contentti, Edgar Carnero, Deri, Norma, Sinay, Vladimiro, and Hryb, Javier
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SARS-CoV-2 Omicron variant ,COVID-19 ,HUMORAL immunity ,DIMETHYL fumarate ,COVID-19 vaccines - Abstract
Introduction: There are no reports in LATAM related to longitudinal humoral and cellular response to adenovirus based COVID-19 vaccines in people with Multiple Sclerosis (pwMS) under different disease modifying therapies (DMTs) and neutralization of the Omicron and Wuhan variants of SARS-COV-2. Methods: IgG anti- SARS-COV-2 spike titer were measured in a cohort of 101 pwMS under fingolimod, dimethyl fumarate, cladribine and antiCD20, as well as 28 healthy controls (HC) were measured 6 weeks after vaccination with 2
nd dose (Sputnik V or AZD1222) and 3nd dose (homologous or heterologous schedule). Neutralizing capacity was against Omicron (BA.1) and Wuhan (D614G) variants and pseudotyped particles and Cellular response were analyzed.Results: Multivariate regression analysis showed anti-cd20 (β= -,349, 95% CI: -3655.6 - -369.01, p=0.017) and fingolimod (β=-,399, 95% CI: -3363.8 - -250.9, p=0.023) treatments as an independent factor associated with low antibody response (r² adjusted=0.157). After the 2nd dose we found a correlation between total and neutralizing titers against D614G (rho=0.6; p<0.001; slope 0.8, 95% CI:0.4-1.3), with no differences between DMTs. Neutralization capacity was lower for BA.1 (slope 0.3, 95%CI:0.1-0.4). After the 3rd dose, neutralization of BA.1 improved (slope: 0.9 95%CI:0.6-1.2), without differences between DMTs. A fraction of pwMS generated anti-Spike CD4+ and CD8+ T cell response. In contrast, pwMS under antiCD20 generated CD8+TNF+IL2+ response without differences with HC, even in the absence of humoral response. The 3rd dose significantly increased the neutralization against the Omicron, as observed in the immunocompetent population. Discussion: Findings regarding humoral and cellular response are consistent with previous reports [ABSTRACT FROM AUTHOR]- Published
- 2024
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20. Real-World Effectiveness and Safety of Cladribine in Multiple Sclerosis: Longitudinal Data From the Nationwide Registry in Argentina.
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Ignacio Rojas, Juan, Alonso, Ricardo, Luetic, Geraldine, Patrucco, Liliana, Casas, Magdalena, Silva, Berenice, Miguez, Jimena, Deri, Norma, Vrech, Carlos, Liwacki, Susana, Piedrabuena, Raúl, Silva, Emanuel, Tkachuk, Verónica, Burgos, Marcos, Tavolini, Dario, Zanga, Gisela, Pinheiro, Amelia Alvez, Hryb, Javier, Leguizamon, Felisa, and Knorre, Eduardo
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- 2024
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21. Consensus recommendations for family planning and pregnancy in multiple sclerosis in argentina
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Liguori, Nora Fernández, Alonso, Ricardo, Pinheiro, Amelia Alves, Balbuena, María E, Barboza, Andrés, Bestoso, Santiago, Burgos, Marcos, Cáceres, Fernando, Carnero Contentti, Edgar, Carrá, Adriana, Cristiano, Edgardo, Curbelo, María C, Deri, Norma, Fiol, Marcela, Gaitán, María I, Garcea, Orlando, Halfon, Mario, Hryb, Javier, Jacobo, Miguel, José, Gustavo, Knorre, Eduardo, López, Pablo, Luetic, Geraldine, Mainella, Carolina, Martínez, Alejandra, Miguez, Jimena, Nofal, Pedro, Pagani Cassará, Fátima, Marcilla, Marcela Parada, Piedrabuena, Raúl, Pita, Cecilia, Quarracino, Cecilia, Rojas, Juan I, Silva, Berenice, Sinay, Vladimiro, Steinberg, Judith, Tarulla, Adriana, Tavolini, Darío, Tkachuk, Verónica, Tizio, Santiago, Villa, Andrés, Vrech, Carlos, Ysrraelit, Célica, and Patrucco, Liliana
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- 2020
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22. Consensus recommendations on the management of multiple sclerosis patients in Argentina
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Cristiano, Edgardo, Rojas, Juan Ignacio, Alonso, Ricardo, Alvez Pinheiro, Amelia, Bacile, Elizabeth A., Balbuena, María Eugenia, Barboza, Andrés G., Bestoso, Santiago, Burgos, Marcos, Cáceres, Fernando, Carnero Contentti, Edgar, Curbelo, María Celeste, Deri, Norma, Fernandez Liguori, Nora, Gaitán, María Ines, Garcea, Orlando, Giunta, Diego, Halfon, Mario J., Hryb, Javier P., Jacobo, Miguel, Kohler, Eduardo, Luetic, Geraldine G., Maglio, Ignacio, Martínez, Alejandra D., Míguez, Jimena, Nofal, Pedro G., Patrucco, Liliana, Piedrabuena, Raúl, Rotta Escalante, Roberto, Saladino, María Laura, Silva, Berenice A., Sinay, Vladimiro, Tkachuk, Verónica, Villa, Andrés, Vrech, Carlos, Ysrraelit, María Célica, and Correale, Jorge
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- 2020
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23. Effectiveness and Safety of Early High-Efficacy Versus Escalation Therapy in Relapsing-Remitting Multiple Sclerosis in Argentina
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Rojas, Juan Ignacio, Patrucco, Liliana, Alonso, Ricardo, Garcea, Orlando, Deri, Norma, Carnero Contentti, Edgar, Lopez, Pablo A., Pettinicchi, Juan Pablo, Caride, Alejandro, and Cristiano, Edgardo
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- 2022
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24. Clinical and demographic characteristics of primary progressive multiple sclerosis in Argentina: Argentinean registry cohort study (RelevarEM)
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Alonso, Ricardo, Quarracino, Cecilia, Eizaguirre, Bárbara, Cohen, Leila, Silva, Berenice, Pita, Cecilia, Rojas, Juan Ignacio, Pappolla, Agustín, Miguez, Jimena, Patrucco, Liliana, Cristiano, Edgardo, Vrech, Carlos, Volman, Gabriel, Silva, Emanuel, Barboza, Andres, Deri, Norma, Tkachuk, Verónica, Zanga, Gisela, Tavolini, Dario, Saladino, María Laura, Luetic, Geraldine, Menichini, María Laura, Carnero Contentti, Edgar, López, Pablo, Steinberg, Judith, Divi, Pablo, Hryb, Javier, Alves Pinheiro, Amelia, Carra, Adriana, Balbuena, María Eugenia, Lázaro, Luciana, Fernández Liguori, Nora, and Garcea, Orlando
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- 2020
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25. The Argentinean multiple sclerosis registry (RelevarEM): Methodological aspects and directions
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Rojas, Juan Ignacio, Carrá, Adriana, Correale, Jorge, Cristiano, Edgardo, Fernández Liguori, Nora, Alonso, Ricardo, Alvez Pinheiro, Amelia, Balbuena, María E., Barboza, Andrés G., Bestoso, Santiago, Blaya, Patricio A., Burgos, Marcos, Cabrera, Lorena M., Caride, Alejandro, Carnero Contentti, Edgar, Cohen, Leila, Curbelo, Celeste, Deri, Norma, Divi, Pablo, Fiol, Marcela, Fracaro, María E., Gaitán, María I., Hryb, Javier, Jacobo, Miguel, Knorre, Eduardo, Leguizamon, Felisa, Giunta, Diego, Alonso Serena, Marina, Doldan, María L., De Lio, Guillermo F., Liwacki, Susana del V., Lopez, Pablo A., Luetic, Geraldine, Mainella, Carolina, Manzi, Ruben, Marrodan, Mariano, Martinez, Alejandra D., Miguez, Jimena, Negrotto, Laura, Nofal, Pedro, Parada Marcilla, Marcela, Pettinicchi, Juan Pablo, Silva, Berenice A., Silva, Emanuel, Silveira, Facundo, Steinberg, Judith D., Tavolini, Dario, Tizio, Santiago, Tkachuk, Verónica, Vazquez, Guido, Volman, Gabriel, Vrech, Carlos, Ysrraelit, María C., Zanga, Gisela, Garcea, Orlando, and Patrucco, Liliana
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- 2019
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26. Natalizumab treatment shows low cumulative probabilities of confirmed disability worsening to EDSS milestones in the long-term setting
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Correale, Jorge, Caride, Alejandro, Deri, Norma H., Ballario, Carlos, Broadley, Simon, Kneebone, Chris, Barnett, Michael, Pollard, John, Hodgkinson, Suzanne, Kermode, Allan, Macdonell, Richard, King, John, Butzkueven, Helmut, Lechner-Scott, Jeannette, Saines, Noel, Slee, Mark, Plummer, Chris, Willekens, Barbara, Vanopdenbosch, Ludo, Belachew, Shibeshih, Phan-Ba, Rémy, Delvaux, Valérie, Bissay, Veronique, Debruyne, Jan, Decoo, Danny, Crols, Roeland, Symons, Anoek, Nagels, Guy, Van Pesch, Vincent, Sindic, Christian, Dubois, Benedicte, Medaer, Robert, D'Hooghe, Marie, Guillaume, Daniel, De Smet, Eric, Seeldrayers, Pierrette, Lysandropoulos, Andreas, Vokaer, Mathieu, Geens, Karine, Willems, Christina, Denayer, Pierre, Bureau, Michel, Retif, Cecile, Dupuis, Michel, Bouquiaux, Olivier, Vanderdonckt, Patrick, van Landegem, William, Caekebeke, Jo, Van Ingelghem, Erwin, Peeters, Katelijne, Gerard, Pascale, de Noordhout, Alain Maertens, Desfontaines, Philippe, Urbain, Etienne, Declercq, Inge, Van Wijmeersch, Bart, Vanroose, Erwin, Wibail, Alain, Barthomolé, Emmanuel, Ursell, Melanie, Sweet, Margaret Elizabeth, Howse, David, Jichici, Draga, Shawush, Melad, Namaka, Mike, Traboulsee, Anthony, Hashimoto, Stan, Lo, Raymond, Marchetti, Paul, Lapierre, Yves, Jacques, Francois, MacLean, Gregg, Bhan, Virender, Duquette, Pierre, Stewart, Bradley, Paulseth, John, Kremenchutzky, Marcelo, Vorobeychik, Galina, O'Connor, Paul, Grand'Maison, François, Havrdova, Eva, Meluzinová, Eva, Valis, Martin, Talab, Radomír, Stourac, Pavel, Zapletalová, Olga, Dufek, Michal, Sládková, Vladimíra, Novotna, Alena, Vancurová, Romana, Lhotaková, Libuse, Fiedler, Jiri, Vachova, Marta, Dolezil, David, Stetkarova, Ivana, Rehankova, Adela, Psenica, Petr, Ulehlova, Veronika, Feketova, Sona, Skoda, Ondrej, Färkkilä, Markus, Taneli, Sarasoja, Koivisto, Keijo, Seppä, Juha Matti, Airas, Laura, Elovaara, Irina, Hartikainen, Päivi, Pirttila, Tuula, Louchart, Pierre, Ille, Olivier, Thenint, Jean philippe, Godet, Etienne, Vioud, Marcel Maillet, Colamarino, Renato, Gugenheim, Michel, Grimaud, Jerome, Kopf, Audrey, Billy, Christophe, Huttin, Bernard, Borsotti, Jean paul, Devos, Philippe, Kendjuo, Jean bertin N, Verier, Albert, Chapuis, Stephane, Daluzeau, Nathalie, Angibaud, Gilles, Uriot, Marie-Sylvie Artaud, Ziegler, François, Sellal, François, Moulignier, Antoine, Lavenu, Isabelle, Ismail, Samir, Devy, Richard, Suceveanu, Manuel, Wagner, Marc, Marcel, Sebastien, Derouiche, Faycal, Mostoufizadehghalamfarsa, Sohrab, Delalande, Sophie, Ruggieri, Irene, Van Nieuwenhuyse, Catherine Bossu, Nifle, Chantal, Ondze, Basile, Vasilescu, Carmen Gurau, Vongsouthi, Cyrille, Coustans, Marc, Anne, Olivier, Amevigbe, Josephine, Servan, Jerome, Merienne, Marc, Eck, Philippe, Berroir, Stephane, Busson, Philippe, Barroso, Bruno, Larrieu, Jean-Marc, Giendaj, Catherine Louvet, Malkoun, Imad, Hautecoeur, Patrick, Kwiatkowski, Arnaud, Pouliquen, Andre, Garrigues, Guillaume, Delerue, Olivier, Giraud, Pierric, Gere, Julien, Vaunaize, Jean, Dereeper, Olivier, Seiller, Nicolas, Alsassa, Roger, Vlaicu, Mihaela, Neuville, Veronique, Faucheux, Jean Marc, Bernady, Patricia, Fanjaud, Guy, Viallet, François, Schroeter, Michael, Schlemilch-Paschen, Sylke, Lange, Thomas, Bohr, Kin-Arno, Jendroska, Klaus, Rehkopf, Elisabeth, Bergmann, Arnfin, Kleinschnitz, Christoph, Postert, Thomas, Scholz, Peter, Mauz, Uwe, Stratmann, Hubert, Siefjediers, Veneta, Prantl, Martin, Gehring, Klaus, Zellner, Ruth, Junge, Kathrin, Zellner, Anton, Bacay, Valerina, Schlegel, Eugen, Polzer, Udo, Strauss, Erik, Link, Andreas, Stenzel, Christoph, Freidel, Matthias, Drews, Joachim, Neudert, Christian, Schmitz, Frank, Jaeger, Joachim, Masri, Said, Heuberger, Wolfgang, Trausch, Beate, Ruhnke, Oliver, Scarel, Serena, Bach, Kathlen, Ernst, Michael, Landefeld, Harald, Richter, Nils, Schmidt, Stephan, Krause, Michaela, Dressel, Alezander, Ruth, Roland, Anvari, Kerstin, Gossling, Jens, Schenk, Christoph, Tiedge, Oliver, Bode, Lutz, Eder, Hans-Thomas, Pfeffer, Oliver, Krug, Reinhard, Lassek, Christoph, Fleischer, Eberhard, Meuth, Sven, Klotz, Luisa Hildegard, Peglau, Ines, Kukowski, Borries, Herting, Birgit, Guthke, Kersten, Schierenbeck, Jurgen, Brockmeier, Bernd, Albrecht, Holger, Wuttke, Matthias, Augspach-Hofmann, Regine, Gunther, Stefan, Redbrake, Martin, Franke, Christian, Buchner, Klaus, Gratz, Thomas, Horn, Rolf, Doemges, Frank, Schreiber, Martin, Brosch, Thomas, Horn, Markus, Kittlitz, Matthias, Vulturius, Gabriele, Hinse, Paul, Malessa, Rolf, Wiehler, Stephan, Katsarava, Zaza, Kastrup, Oliver, Kausch, Ulrich, Gullekes, Martin, Fickinger, Markus, Wenzel, Wilhelm, Botefur, Ingolf C., Reifschneider, Gerd, Rauer, Sebastian, Lang, Michael, Harms, Lutz, Eckhardt, Ulrich, Cursiefen, Simone, Linker, Ralf, Angstwurm, Klemens, Haas, Judith, Schuetze, Ivo, Rohm, Eva, Stienker-Fisse, H., Sailer, Michael, Bohringer, Johannes, Maurer, Mathias, Bause, Eberhard, Wersching, Ronald, Dachsel, Reinhardt, Domke, Sylke, Hoffman, Frank, Tackenberg, Bjorn, Roch, Kerstin, Ziebold, Uwe, Kallmann, Boris, Buehler, Bernhard, Faiss, Judith, Faiss, Juergen, Schimrigk, Sebastian, Menges, Christian, Knop, Karl Christian, Koehler, Wolfgang, Siever, Arno, Bufler, Johannes, Gramsl, Georg, Kuhnler, Benedicta, Maschke, Matthias, Stogbauer, Florian, Staude, Lisa, Bethke, Florian, Bitsch, Andreas, Harmjanz, Arndt D., Windsheimer, Jorg, Kieseier, Bernd C., Berkenfeld, Ralf, Tumani, Hayrettin, Kirsch, Michael, Wildemann, Brigitte, Daniels, Regina, Gottwald, Klaus, Elias, Wolfgang-Gerhard, Hoffmann, Olaf, Schwab, Matthias, Pilz, Christopher, Klostermann, Fabian, Hellwig, Kerstin, Berthele, Achim, Bayas, Antonios, Molitor, Daniel, Grothe, Christoph, Wagner, Bert, Karageorgiou, Klimentini, Mitsikostas, Dimosthenis, Kodounis, Antonios, Plaitakis, Andreas, Papadimitriou, Alexandros, Grigoriadis, Nikolaos, Vlaikidis, Nikolaos, Koutlas, Evaggelos, Kyritsis, Athanassios, Papathanassopoulos, Panagiotis, Makris, Nikolaos, Tavernarakis, Antonios, Scarpini, Elio, Montanari, Enrico, Marrosu, Maria Giovanna, Trojano, Maria, Amato, Maria Pia, Rottoli, Mariarosa, Lugaresi, Alessandra, Florio, Ciro, Gasperini, Claudio, Grimaldi, Luigi, Millefiorini, Enrico, Koudriavtseva, Tatiana, Perla, Franco, Mantegazza, Renato, Bertolotto, Antonio, Ghezzi, Angelo, Aguilar, Sandra Quinones, Eisenberg, Eli Skromne, Lopez, Leondardo Llamas, Estudillo, Rocio Marquez, Schrijver, H.M., Wittebol, M.C., Baart, J.C., van Golde, A.E.L., Hengstman, G.J.D., Pop, P.H.M., Bos (Geldrop), M., Medaer, R., Schyns-Soeterboek, Angelique, van der Zwart, A., van Diepen, A.J.H., Verheul, G.A.M., Verhagen, W.I.M., Bos (Helmond), M., Witjes, R.J.G.M., Sinnige, L.G.F., van Munster, E.Th.L., Sanders, E.A.C.M., van Dijl, Ron, Hupperts, R.M.M., Frequin, S.T.F.M., Visser, L.H., Henselmans, J.M.L., Moll, J.W.B., Midgard, Rune, Myhr, Kjell Morten, Edland, Astrid, Telstad, Wenche, Hognestad, Tone, Lund, Christian, Hovdal, Harald, Kamaljit, Kaur, Schepel, Jan, Hogenesch, Roelfien Ida, Schüler, Stephan, Odeh, Francis, Alstadhaug, Karl B., Korsgaard, Olav, Farbu, Elisabeth, Ingvaldsen, Teis Barclay, Soares (SCO), Diana, Rente, José, Guerra, José Manuel Costa, Morganho, Armando, Leitão, António, de Sá, João, Sá, Maria José, Marques, Pinto, Veloso, Mário, Baptista, Miguel Viana, Szilasiová, Jarmila, Copikova-Cudrakova, Daniela, Prochazkova, Lubica, Klimová, Eleonóra, Donath, Vladimir, Brozman, Miroslav, Ramo, Cristina, Ruiz, Domingo Pérez, Hernández, Carmen Calles, Sola, María Eugenia Marzo, Moro, Roberto Suarez, Vidal, Jose Antonio, Rodríguez, Ana Belén Caminero, Ozaeta, Gisela Martin, Nadal, Jordi Batlle, Esquide, Amaya Alvarez de Arcaya, Urtaza, Javier Olascoaga, Martínez-Yélamos, Sergio, Arbizu, Txomin, Torrenta, Lluis Ramio i, Boggild, Mike, Wilson, Martin, Al-Araji, Adnan, Nicholas, Richard, Harrower, Timothy, Redmond, Ian, Wolf, Tilo, Osei-Bonsu, Michael, Mazibrada, Gordon, Rog, David, Cottrell, David, Constantinescu, Cris, Gray, Orla, Belhag, Mohamed, Shehu, Abdullah, Rashid, Waqar, Duddy, Martin, Kappos, Ludwig, Wiendl, Heinz, Spelman, Tim, Pellegrini, Fabio, Chen, Yi, Dong, Qunming, and Koendgen, Harold
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- 2018
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27. Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study
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Achiron, Anat, Achtnichts, Lutz, Agan, Kadriye, Akman-Demir, Gulsen, Allen, Alison B, Antel, Jack P, Antiguedad, Alfredo Rodriguez, Apperson, Michelle, Applebee, Angela M, Ayuso, Guillermo Izquierdo, Baba, Masayuki, Bajenaru, Ovidiu, Balasa, Rodica, Balci, Belgin Petek, Barnett, Michael, Bass, Ann, Becker, Veit U, Bejinariu, Mihaela, Bergh, Florian Then, Bergmann, Arnfin, Bernitsas, Evanthia, Berthele, Achim, Bhan, Virender, Bischof, Felix, Bjork, Randall John, Blevins, Gregg, Boehringer, Matthias, Boerner, Thomas, Bonek, Robert, Bowen, James D, Bowling, Allen, Boyko, Alexey N, Boz, Cavit, Bracknies, Vera, Braune, Stefan, Brescia Morra, Vincenzo, Brochet, Bruno, Brola, Waldemar, Brownstone, Paul Kenneth, Brozman, Miroslav, Brunet, Donald, Buraga, Ioan, Burnett, Margaret, Buttmann, Mathias, Butzkueven, Helmut, Cahill, Jonathan, Calkwood, Jonathan C, Camu, William, Cascione, Mark, Castelnovo, Giovani, Centonze, Diego, Cerqueira, Joao, Chan, Andrew, Cimprichova, Andrea, Cohan, Stanley, Comi, Giancarlo, Conway, Jill, Cooper, Joanna A, Corboy, John, Correale, Jorge, Costell, Brian, Cottrell, David A, Coyle, Patricia K, Craner, Matthew, Cui, Liying, Cunha, Luis, Czlonkowska, Anna, da Silva, Ana Martins, de Sa, Joao, de Seze, Jérôme, Debouverie, Marc, Debruyne, Jan, Decoo, Danny, Defer, Gilles, Derfuss, Tobias, Deri, Norma H, Dihenia, Bhupesh, Dioszeghy, Peter, Donath, Vladimir, Dubois, Benedicte, Duddy, Martin, Duquette, Pierre, Edan, Gilles, Efendi, Husnu, Elias, Stanton, Emrich, Peter J, Estruch, Bonaventura Casanova, Evdoshenko, Evgeniy P, Faiss, Juergen, Fedyanin, Alexander S, Feneberg, Wolfgang, Fermont, Jiske, Fernandez, Oscar Fernandez, Ferrer, Francisco Coret, Fink, Katharina, Ford, Helen, Ford, Corey, Francia, Ada, Freedman, Mark, Frishberg, Benjamin, Galgani, Simonetta, Garmany, George P, Gehring, Klaus, Gitt, Jeffrey, Gobbi, Claudio, Goldstick, Lawrence P, Gonzalez, Rafael Arroyo, Grandmaison, Francois, Grigoriadis, Nikolaos, Grigorova, Olga, Grimaldi, Luigi Maria Edoardo, Gross, Jeffrey, Gross-Paju, Katrin, Gudesblatt, Mark, Guillaume, Daniel, Haas, Judith, Hancinova, Viera, Hancu, Anca, Hardiman, Orla, Harmjanz, Arndt, Heidenreich, Fedor R, Hengstman, G J D, Herbert, Joseph, Herring, Mark, Hodgkinson, Suzanne, Hoffmann, Olaf M, Hofmann, Werner E, Honeycutt, William D, Hua, Le Hanh, Huang, Dehui, Huang, Yining, Huang, DeRen, Hupperts, Raymond, Imre, Piroska, Jacobs, Alan Keith, Jakab, Gabor, Jasinska, Elzbieta, Kaida, Kenichi, Kalnina, Jolanta, Kaprelyan, Ara, Karelis, Guntis, Karussis, Dimitrios, Katz, Amos, Khabirov, Farit A, Khatri, Bhupendra, Kimura, Takashi, Kister, Ilya, Kizlaitiene, Rasa, Klimova, Eleonora, Koehler, Juergen, Komatineni, Aparna, Kornhuber, Anselm, Kovacs, Krisztina, Koves, Agnes, Kozubski, Wojciech, Krastev, Georgi, Krupp, Lauren B, Kurca, Egon, Lassek, Christoph, Laureys, Guy, Lee, Liesly, Lensch, Eckart, Leutmezer, Fritz, Li, Hongzeng, Linker, Ralf A, Linnebank, Michael, Liskova, Petra, Llanera, Cristina, Lu, Jiahong, Lutterotti, Andreas, Lycke, Jan, Macdonell, Richard, Maciejowski, Maciej, Maeurer, Mathias, Magzhanov, Rim V, Maida, Eva-Maria, Malciene, Lina, Mao-Draayer, Yang, Marfia, Girolama Alessandra, Markowitz, Clyde, Mastorodimos, Vasileios, Matyas, Klotild, Meca-Lallana, Jose, Merino, Juan Antonio Garcia, Mihetiu, Ioan Gheorghe, Milanov, Ivan, Miller, Aaron E, Millers, Andrejs, Mirabella, Massimiliano, Mizuno, Masanori, Montalban, Xavier, Montoya, Lilina, Mori, Masahiro, Mueller, Stefanie, Nakahara, Jin, Nakatsuji, Yuji, Newsome, Scott, Nicholas, Richard, Nielsen, A Scott, Nikfekr, Esmaeil, Nocentini, Ugo, Nohara, Chiyoko, Nomura, Kyoichi, Odinak, Miroslav M, Olsson, Tomas, van Oosten, B W, Oreja-Guevara, Celia, Oschmann, Patrick, Overell, James, Pachner, Andrew, Panczel, Gyula, Pandolfo, Massimo, Papeix, Caroline, Patrucco, Liliana, Pelletier, Jean, Piedrabuena, Raul, Pless, Misha, Polzer, Udo, Pozsegovits, Krisztian, Rastenyte, Daiva, Rauer, Sebastian, Reifschneider, Gerd, Rey, Roberto, Rizvi, Syed A, Robertson, Derrick, Rodriguez, Jose Martinez, Rog, David, Roshanisefat, Homayoun, Rowe, Vernon, Rozsa, Csilla, Rubin, Susan, Rusek, Stanislaw, Saccà, Francesco, Saida, Takahiko, Salgado, Antonio Vasco, Sanchez, Victoria Eugenia Fernandez, Sanders, Kalina, Satori, Maria, Sazonov, Denis V, Scarpini, Elio Angelo, Schlegel, Eugen, Schluep, Myriam, Schmidt, Stephan, Scholz, Erich, Schrijver, H M, Schwab, Matthias, Schwartz, Raymond, Scott, James, Selmaj, Krzysztof, Shafer, Stuart, Sharrack, Basil, Shchukin, Ivan A, Shimizu, Yuko, Shotekov, Penko, Siever, Arno, Sigel, Karl-Otto, Silliman, Scott, Simo, Magdolna, Simu, Mihaela, Sinay, Vladimiro, Siquier, Antonio Escartin, Siva, Aksel, Skoda, Ondrej, Solomon, Andrew, Stangel, Martin, Stefoski, Dusan, Steingo, Brian, Stolyarov, Igor D, Stourac, Pavel, Strassburger-Krogias, Katrin, Strauss, Erik, Stuve, Olaf, Tarnev, Ivaylo, Tavernarakis, Antonios, Tello, Cristina Ramo, Terzi, Murat, Ticha, Veronika, Ticmeanu, Marina, Tiel-Wilck, Klaus, Toomsoo, Toomas, Tubridy, Niall, Tullman, Mark J, Tumani, Hayrettin, Turcani, Peter, Turner, Ben, Uccelli, Antonio, Urtaza, Francisco Javier Olascoaga, Vachova, Marta, Valikovics, Attila, Walter, Silke, Van Wijmeersch, Bart, Vanopdenbosch, Ludo, Weber, Joerg R, Weiss, Sara, Weissert, Robert, Vermersch, Patrick, West, Timothy, Wiendl, Heinz, Wiertlewski, Sandrine, Wildemann, Brigitte, Willekens, Barbara, Visser, L H, Vorobeychik, Galina, Xu, Xianhao, Yamamura, Takashi, Yang, Yi N, Yelamos, Sergio Martinez, Yeung, Michael, Zacharias, Alan, Zelkowitz, Marvin, Zettl, Uwe, Zhang, Meini, Zhou, Hongyu, Zieman, Ulf, Ziemssen, Tjalf, Kappos, Ludwig, Bar-Or, Amit, Cree, Bruce A C, Fox, Robert J, Giovannoni, Gavin, Gold, Ralf, Arnold, Douglas L, Arnould, Sophie, Scherz, Tatiana, Wolf, Christian, Wallström, Erik, and Dahlke, Frank
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- 2018
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28. Bases racionales de prescripción para médicos neurólogos
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Orellana, Lucas, Aleman, Alberto, Barboza, Andrés, Bernater, Ricardo, Demey, Ignacio, Deri, Norma, Fumagalli, Ana Isabel, Kriebaum, Martín, Martinez, Alejandra, Martinez, Oscar, Papayannis, Cristina, Parada Marcilla, Marcela, Rojas, Galeno, Romano, Lucas Martin, Romano, Marina, Saidon, Patricia, and Steinberg, Judith
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- 2016
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29. Frequency of new asymptomatic MRI lesions during attacks and follow-up of patients with NMOSD in a real-world setting.
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Carnero Contentti, Edgar, Lopez, Pablo A, Tkachuk, Verónica, Vrech, Carlos, Zarate, María A, Correale, Jorge, Deri, Norma, Luetic, Geraldine, Marrodan, Mariano, Pagani Cassara, Fátima, Tavolini, Darío, Ysrraelit, María Célica, Balbuena, María E, Hryb, Javier, Chiganer, Edson, Leguizamon, Felisa, Knorre, Eduardo, Zanga, Gisela, Pestchanker, Claudia, and Barboza, Andrés
- Subjects
NEUROMYELITIS optica ,MAGNETIC resonance imaging ,OPTIC nerve injuries - Abstract
Background: We aimed to assess the frequency of new asymptomatic lesions on brain and spinal imaging (magnetic resonance imaging (MRI)) and their association with subsequent relapses in a large cohort of neuromyelitis optica spectrum disorder (NMOSD) patients in Argentina. Methods: We retrospectively reviewed 675 MRI (225 performed during an attack and 450 during the relapse-free period (performed at least 3 months from the last attack)) of NMOSD patients who had at least 2 years of clinical and MRI follow-up since disease onset. Kaplan–Meier (KM) curves were used for depicting time from remission MRI to subsequent relapse. Results: We included 135 NMOSD patients (64.4% were aquaporin-4-immunoglobulin G (AQP4-IgG)-positive). We found that 26 (19.26%) and 66 (48.88%) of patients experienced at least one new asymptomatic MRI lesion during both the relapse-free period and attacks, respectively. The most frequent asymptomatic MRI lesions were optic nerves followed by short-segment myelitis during the relapse-free period and attacks. KM curves did not show differences in the time taken to develop a new relapse. Conclusion: Our findings showed that new asymptomatic lesions are relatively frequent. However, the presence of new asymptomatic MRI lesions during the relapse-free period and at relapses was not associated with a shorter time to developing subsequent relapses. [ABSTRACT FROM AUTHOR]
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- 2023
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30. SEROLOGICAL RESPONSE TO SARS-COV-2 VACCINES IN PATIENTS WITH MULTIPLE SCLEROSIS IN ARGENTINA.
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ROJAS, JUAN I., ALONSO, RICARDO, CABRERA, MARIELA, CONTENTTI, EDGAR CARNERO, CRISTIANO, EDGARDO, DERI, NORMA, HRYB, JAVIER, LOPEZ, PABLO, LUETIC, GERALDINE, PATRUCCO, LILIANA, TKACHUK, VERONICA, YSRRAELIT, MARÍA C., ZANGA, GISELA, CRUCES, LEONEL, TURK, GABRIELA, LONGUEIRA, YESICA, LAUFER, NATALIA, and NUÑEZ, SEBASTIAN
- Abstract
Introduction: The objective was to assess the immunogenicity and effectiveness of vaccines against SARSCoV-2 in multiple sclerosis (MS) patients included in the Argentinean MS registry. Methods: A prospective cohort study between May and December 2021. The primary outcome was immunogenicity and effectiveness of vaccines during a three-month follow-up. Immunogenicity was evaluated based on detection of total antibodies (Ab) against spike protein and neutralizing Ab in serum 4 weeks after the second vaccine dose. A positive COVID-19 case was defined according to Argentinean Ministry of Health. Results: 94 patients were included, mean age: 41.7 ± 12.1 years. Eighty (85.1%) had relapsing remitting multiple sclerosis (RRMS); 30 (31.9%) were under fingolimod treatment. The Sputnik V vaccine was the first dose in 33 (35.1%), and AstraZeneca in 61 (64.9%). In 60 (63.8%), the vaccine elicited a specific humoral response. Immunological response according to the vaccination schemes showed no qualitative differences (p = 0.45). Stratified analysis according to the MS treatment showed that a significantly smaller number of subjects developed antibodies against spike antigen among those that were on ocrelizumab compared to other groups (p ≤ 0.001), while a reduced number of patients under ocrelizumab where evaluated (n = 7). This was also observed for neutralizing antibodies in the ocrelizumab group (p < 0.001). During the three-month follow-up, two individuals were diagnosed with COVID-19. Conclusion: We found that MS patients that received Sputnik V or AstraZeneca vaccines for SARS-CoV-2 developed a serological response with no differences between the vaccines used. [ABSTRACT FROM AUTHOR]
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- 2023
31. Seasonal variation of relapse rate in multiple sclerosis is latitude dependent
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Spelman, Tim, Gray, Orla, Trojano, Maria, Petersen, Thor, Izquierdo, Guillermo, Lugaresi, Alessandra, Hupperts, Raymond, Bergamaschi, Roberto, Duquette, Pierre, Grammond, Pierre, Giuliani, Giorgio, Boz, Cavit, Verheul, Freek, Oreja-Guevara, Celia, Barnett, Michael, GrandʼMaison, Francois, Edite Rio, Maria, Lechner-Scott, Jeannette, Van Pesch, Vincent, Fernandez Bolanos, Ricardo, Flechter, Shlomo, Den Braber-Moerland, Leontien, Iuliano, Gerardo, Amato, Maria Pia, Slee, Mark, Cristiano, Edgardo, Saladino, Maria Laura, Paine, Mark, Vella, Norbert, Kasa, Krisztian, Deri, Norma, Herbert, Joseph, Moore, Fraser, Petkovska-Boskova, Tatjana, Alroughani, Raed, Savino, Aldo, Shaw, Cameron, Vucic, Steve, Santiago, Vetere, Bacile, Elizabeth Alejandra, Skromne, Eli, Poehlau, Dieter, Cabrera-Gomez, Jose Antonio, Lucas, Robyn, and Butzkueven, Helmut
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- 2014
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32. Preferences for Disease-Modifying Therapies in Argentina: Cross-Sectional Conjoint Analysis of Patients and Neurologists.
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Rojas, Juan I., Patrucco, Liliana, Alonso, Ricardo, Lopez, Pablo A., Deri, Norma, Pettinicchi, Juan Pablo, Cristiano, Edgardo, and Carnero Contentti, Edgar
- Abstract
The objective of this study was to determine by a conjoint analysis the preferences for a range of disease-modifying treatment attributes in patients with multiple sclerosis (MS) and treating neurologists. This was a cross-sectional study throughout Argentina between August 2020 and February 2021. Participating patients were adults with relapsing-remitting MS, who had received a long-term specific disease-modifying treatment for at least the past 3 months and their treating neurologist. Patients and neurologist were sampled from the Argentinean MS patient registry (RelevarEM). We applied the methodology of conjoint analysis. Patient preferences for hypothetical treatment were collected from the overall sample and from stratified subgroups according to the expanded disability status scale (EDSS) score. An ordinary least squares regression model was used to estimate parameters. A total of 275 patients from 25 centers (31 principal investigators) were included, mean age was 43.2 ± 10.9 years, 59.6% were female, and mean EDSS was 3.1 ± 2. For the entire sample, we observed that patients had higher preferences for treatments with lower side effect risks (28.7 relative preference [RP]), lower frequency of administration (21.4 RP), and higher impact on relapses (19.6 RP). Patients with a higher EDSS give significantly greater importance to a less frequent administration regime and the oral route than patients with a lower EDSS (23.5 RP vs 20.1 [ P =.02] and 17.1 vs 15.3 [ P =.03], respectively). For neurologists, the most important attribute was to prevent disease progression (RP 29.3). Our study contributes to the understanding of treatment selection preferences from the perspectives of both patient and neurologists. • This was a cross-sectional analysis that included 275 patients from 25 centers. • Patients had higher preferences for treatments with lower side effect risks (28.7 average preference). • In the neurologist sample, the most important attribute was to prevent disease progression (average preference 30.2). [ABSTRACT FROM AUTHOR]
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- 2022
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33. Traditional first-line treatment failure rates in neuromyelitis optica spectrum disorder patients included in the Argentinean registry (RelevarEM).
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Carnero Contentti, Edgar, Lopez, Pablo A, Patrucco, Liliana, Cristiano, Edgardo, Miguez, Jimena, Silva, Berenice, Liwacki, Susana, Tkachuk, Verónica, Balbuena, María E, Vrech, Carlos, Deri, Norma, Correale, Jorge, Marrodan, Mariano, Ysrraelit, María C, Fiol, Marcela, Leguizamon, Felisa, Luetic, Geraldine, Tavolini, Darío, Mainella, Carolina, and Zanga, Gisela
- Abstract
• We studied 139 NMOSD patients from Argentina on AZA (n = 105), MMF (n = 5), or RTX (n = 29). • The annualized relapse rate decreased post-treatment in 51.1 %, 48.4 %, and 79.1 % of cases. • RTX showed a significantly lower risk compared to AZA (HR= 1.67, 95 %CI 1.34–3.54, p = 0.01) and MMF (HR= 2.01, 95 %CI 1.86–4.43, p = 0.008). • 49/105 (46.6 %) on AZA, 2/5 (40 %) on MMF, and 4/29 (13.8 %) on RTX switched therapies due to treatment failure. • Higher neurological disability and longer time to treatment initiation increased relapse risk with traditional first-line IST. Immunosuppressive therapies as azathioprine (AZA), mycophenolate mofetil (MMF) and rituximab (RTX) are widely prescribed as first-line treatment to prevent relapses in NMOSD. However, the rate of response to these traditional therapies is unknown in Argentina. We aimed to describe and compare treatment failure rates in NMOSD patients included in the Argentinean MS and NMOSD registry (RelevarEM, NCT 03375177). A retrospective cohort study was conducted in NMOSD patients included in RelevarEM (a nationwide, longitudinal, observational, non-mandatory registry of MS and NMOSD in Argentina). NMOSD patients were defined based on validate diagnostic criteria. Only NMOSD patients who received AZA or MMF for at least 6 months or RTX for at least 1 month were included. Patients who were receiving AZA, MMF, or RTX and then switched to another 1 of these 3 therapies were included if the above-mentioned criteria for each drug were fulfilled. Data on patient demographics, clinical, neuroradiological findings, and treatments administered were collected. Treatment failure was defined as any new attack/relapse that occurred despite immunosuppressive treatment. We included 139 NMOSD patients who were receiving AZA (n = 105), MMF (n = 5) or RTX (n = 29) with a mean follow-up time of 41.3 ± 11.4 months and median of EDSS at treatment initiation of 3. We observed a reduction in the annualized relapse rate from pre-treatment to post-treatment of 51.1 %, 48.4 %, and 79.1 % respectively with a Hazard Risk relative to RTX (95 % CI) of 1.67 (1.34–3.54, p = 0.01) for AZA and 2.01 (1.86–4.43, p = 0.008) for MMF. AZA, MMF and RTX failure was observed in 45/105 (42.8 %), 2/5 (40 %) and 3/29 (10.3 %) patients, respectively. Treatment failure rates were higher for AZA and MMF than RTX in Argentinean NMOSD patients in a real-world setting. High-efficacy treatment increases the opportunity to prevent attacks of NMOSD. [ABSTRACT FROM AUTHOR]
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- 2024
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34. Assessing attacks and treatment response rates among adult patients with NMOSD and MOGAD: Data from a nationwide registry in Argentina.
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Carnero Contentti, Edgar, Lopez, Pablo A, Pettinicchi, Juan Pablo, Criniti, Juan, Pappolla, Agustín, Miguez, Jimena, Patrucco, Liliana, Cristiano, Edgardo, Liwacki, Susana, Tkachuk, Verónica, Balbuena, María E, Vrech, Carlos, Deri, Norma, Correale, Jorge, Marrodan, Mariano, Ysrraelit, María C, Leguizamon, Felisa, Luetic, Geraldine, Menichini, María L, and Tavolini, Darío
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ADULTS ,NEUROMYELITIS optica ,GENERALIZED estimating equations ,OPTIC neuritis - Abstract
We aimed to examine treatment interventions implemented in patients experiencing neuromyelitis optica spectrum disorders (NMOSD) attacks (frequency, types, and response). Methods: Retrospective study. Data on patient demographic, clinical and radiological findings, and administered treatments were collected. Remission status (complete [CR], partial [PR], no remission [NR]), based on changes in the EDSS score was evaluated before treatment, during attack, and at 6 months. CR was analyzed with a generalized estimating equations (GEEs) model. Results: A total of 131 patients (120 NMOSD and 11 myelin oligodendrocyte glycoprotein-antibody-associated diseases [MOGAD]), experiencing 262 NMOSD-related attacks and receiving 270 treatments were included. High-dose steroids (81.4%) was the most frequent treatment followed by plasmapheresis (15.5%). CR from attacks was observed in 47% (105/223) of all treated patients. During the first attack, we observed CR:71.2%, PR:16.3% and NR:12.5% after the first course of treatment. For second, third, fourth, and fifth attacks, CR was observed in 31.1%, 10.7%, 27.3%, and 33.3%, respectively. Remission rates were higher for optic neuritis vs. myelitis (p < 0.001). Predictor of CR in multivariate GEE analysis was age in both NMOSD (OR = 2.27, p = 0.002) and MOGAD (OR = 1.53, p = 0.03). Conclusions: This study suggests individualization of treatment according to age and attack manifestation. The outcome of attacks was generally poor. [ABSTRACT FROM AUTHOR]
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- 2021
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35. Family planning in Argentinian women with multiple sclerosis: An important yet seldom approached issue.
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Alonso, Ricardo, Patrucco, Liliana, Silva, Berenice, Quarracino, Cecilia, Eizaguirre, María Barbara, Vrech, Carlos, López, Pablo, Carnero Contentti, Edgar, Deri, Norma, Carrá, Adriana, Chercorff, Aníbal, Tkachuk, Verónica, Balbuena, María Eugenia, Pettinicchi, Juan Pablo, Tavolini, Darío, Barboza, Andrés, Rojas, Juan I, Cristiano, Edgardo, Lázaro, Luciana, and Garcea, Orlando
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FAMILY planning ,MULTIPLE sclerosis ,MULTIPLE pregnancy ,UNPLANNED pregnancy ,UNIVARIATE analysis - Abstract
Background: The purpose of this study was to assess family planning (FP) among women with multiple sclerosis (WwMS). Methods: We invited 604 WwMS to answer a survey focused on FP: a) Temporal relationship between pregnancy and the diagnosis of multiple sclerosis; b) History of FP; c) Childbearing desire; d) Information on family planning. Comparisons between pregnancy and not pregnancy after MS, as well as, planned and unplanned pregnancy were analyzed. Multivariate and univariate analyses were used to assess the impact of independent variables and FP Result: 428 (71.7%) WwMS completed the survey. A 19.1% got pregnant after MS diagnosis and we evaluated FP in the last pregnancy, 56.1% patients had a planned pregnancy. Professional addressing FP (OR = 0.27, 95%-CI 0.08-0.92, p = 0.03) and non-injection drug treatment before pregnancy (OR = 2.88, 95%-CI 1.01-8.21, p = 0.047) were independent predictors of unplanned pregnancy in our multivariate model. Among WwMS ≤ 40 years, 48.7% had future childbearing desire. Young age (p < 0.001), PDDS <3 (p = 0.018), disease duration <5 years (p = 0.02), not childbearing before MS diagnosis (p < 0.001) and neurologist addressing family planning (p = 0.01) were significantly associated with childbearing desire. Conclusions: This research highlights that pregnancy remains an important concern among WwMS. [ABSTRACT FROM AUTHOR]
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- 2021
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36. Clinical characterization of long-term multiple sclerosis (COLuMbus) patients in Argentina: A cross-sectional non-interventional study.
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Deri, Norma, Barboza, Andres, Vrech, Carlos, Rey, Roberto, Burgos, Marcos, Fiol, Marcela, CalvoVildoso, Cristian, Patrucco, Liliana, Jose, Gustavo, Aliberti, Paula, Chirico, Daniela, Federico, Maria B., Seifer, Gustavo, and Piedrabuena, Raul
- Abstract
• RRMS patients with ≥10 years of MS disease duration since the first diagnosis were fully ambulatory and without aid. However, more than half of those patients were at medium or high risk of disability progression. • Patients in the SPMS subgroup showed severe disability (median EDSS 6.5) and relied on walking aids. • There is the urgent need to monitor the progression of MS as soon as it is identified to delay patient disability and improve their quality of life. Most Multiple Sclerosis (MS) clinical trials fail to assess the long-term effects of disease-modifying therapies (DMT) or disability. COLuMbus was a single-visit, cross-sectional study in Argentina in adult patients with ≥10 years of MS since first diagnosis. The primary endpoint was to determine patient disability using the Expanded Disability Status Scale (EDSS). The secondary endpoints were to evaluate the distribution of diagnoses between relapsing-remitting MS (RRMS) and secondary progressive MS (SPMS), patient demographics, disease history, and the risk of disability progression. The relationship between baseline characteristics and the current disability state and the risk of disability progression was assessed. Out of the 210 patients included, 76.7 % had a diagnosis of RRMS and 23.3 % had been diagnosed with SPMS, with a mean disease duration of 17.9 years and 20.5 years, respectively. The mean delay in the initial MS diagnosis was 2.6 years for the RRMS subgroup and 2.8 years for the SPMS subgroups. At the time of cut-off (28May2020), 90.1 % (RRMS) and 75.5 % (SPMS) of patients were receiving a DMT, with a mean of 1.5 and 2.0 prior DMTs, respectively. The median EDSS scores were 2.5 (RRMS) and 6.5 (SPMS). In the RRMS and SPMS subgroups, 23 % and 95.9 % of patients were at high risk of disability, respectively; the time since first diagnosis showed a significant correlation with the degree of disability. This is the first local real-world study in patients with long-term MS that highlights the importance of recognizing early disease progression to treat the disease on time and delay disability. [Display omitted] [ABSTRACT FROM AUTHOR]
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- 2024
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37. ENCOMS: Argentinian survey in cost of illness and unmet needs in multiple sclerosis.
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Ysrraelit, Celica, Caceres, Fernando, Villa, Andres, Parada Marcilla, Marcela, Blanche, Jorge, Burgos, Marcos, Casas Parera, Ignacio, Colombo, Oscar, Crespo, Ernesto, Deri, Norma, Labal, Patricio, Maluendez, Monica, Martinez, Alejandra, Melcon, Mario, Nofal, Pedro, Reich, Edgardo, Sinay, Vladimiro, Tarulla, Adriana, Vetere, Santiago, and Barboza, Andres
- Abstract
Copyright of Arquivos de Neuro-Psiquiatria is the property of Thieme Medical Publishing Inc. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2014
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38. COVID-19 in Argentine teriflunomide-treated multiple sclerosis patients: First national case series.
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Luetic, Geraldine, Menichini, María L., Burgos, Marcos, Alonso, Ricardo, Carnero Contentti, Edgar, Carrá, Adriana, Deri, Norma, Steinberg, Judith, and Rojas, Juan I.
- Abstract
• Multicentre study including MS patients receiving teriflunomide in Argentina who developed COVID-19. • Eighteen MS patients from eight MS centres were included. • COVID-19 diagnosis was made with nasal swab in 61% and based on clinical criteria in 39%. • All patients were managed in an outpatient setting and they fully recovered within 7-14 days. • None of the patients discontinued their teriflunomide therapy during COVID-19 course. We report COVID-19 presentation, course and outcomes in teriflunomide-treated MS patients in Argentina. Methods : descriptive, retrospective, multicentre, study that included MS patients receiving teriflunomide who developed COVID-19, with clinical follow-up at reference MS centres, also listed in a nationwide registry. Results : Eighteen MS patients on teriflunomide treatment, from eight MS centres developed COVID-19. The mean age was 41,2 years and 72% of them were female; 94% had diagnosis of relapsing-remitting MS and 6% presented a radiologically isolated syndrome. Median EDSS was 2 (range 0-5.5). The average time on teriflunomide therapy was 3 years. COVID-19 diagnosis was confirmed with nasal swab in 61%. None required hospitalization and they completely recovered from the acute-phase within 7-14 days. All the patients continued their teriflunomide therapy during COVID-19 course. No MS relapses occurred during or after COVID-19 course. Conclusion : Our report adds to the evidence that COVID-19 is mild in patients receiving teriflunomide therapy and that continuing with teriflunomide therapy during Sars-CoV-2 infection is safe and advisable for MS patients. [ABSTRACT FROM AUTHOR]
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- 2021
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39. Diagnostic uncertainty during the transition to secondary progressive multiple sclerosis: Multicenter study in Argentina.
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Rojas, Juan Ignacio, Patrucco, Liliana, Alonso, Ricardo, Garcea, Orlando, Deri, Norma, Carnero Contentti, Edgar, Lopez, Pablo A, Pettinicchi, Juan Pablo, Caride, Alejandro, and Cristiano, Edgardo
- Abstract
A period of diagnostic uncertainty often characterizes the clinical transition from relapsing to secondary progressive multiple sclerosis (SPMS).The aim of this study was to describe the length of time required to reclassify relapsing-remitting MS (RRMS) patients who have clinically transitioned to SPMS (diagnosis uncertainty).This is a retrospective multicenter cohort study conducted in Argentina, identifying in every center all patients with diagnosis of MS who transitioned from RRMS to SPMS during the follow-up. We identified the dates of the last definitive RRMS and first definitive SPMS diagnoses for diagnostic uncertainty. The time required to reclassify RRMS who transitioned to SPMS and the time from disease onset to reclassify SPMS were calculated using the Kaplan–Meier method.A total of 170 patients were included, where the mean age at disease onset (first symptom) was 36 ± 6 years; the length of time required to reclassify RRMS patients who transitioned to SPMS was 3.3 ± 1.1 years (range = 1–7 years); and the time from disease onset to classify SPMS was 19.4 ± 8.5 years (range = 16–35 years).A period of diagnostic uncertainty regarding the transition from RRMS to SPMS was present in many of our patients, with a mean time of 3.3 years. [ABSTRACT FROM AUTHOR]
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- 2020
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