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3. GRADE guidance 39: using GRADE-ADOLOPMENT to adopt, adapt or create contextualized recommendations from source guidelines and evidence syntheses

Author

Klugar, Miloslav, Lotfi, Tamara, Darzi, Andrea J., Reinap, Marge, Klugarová, Jitka, Kantorová, Lucia, Xia, Jun, Brignardello-Petersen, Romina, Pokorná, Andrea, Hazlewood, Glen, Munn, Zachary, Morgan, Rebecca L., Toews, Ingrid, Neumann, Ignacio, Bhatarasakoon, Patraporn, Stein, Airton Tetelbom, McCaul, Michael, Mathioudakis, Alexander G., D'Anci, Kristen E., Leontiadis, Grigorios I., Naude, Celeste, Vasanthan, Lenny T., Khabsa, Joanne, Bala, Malgorzata M., Mustafa, Reem, DiValerio Gibbs, Karen, Nieuwlaat, Robby, Santesso, Nancy, Pieper, Dawid, Mokrane, Saphia, Soghier, Israa, Lertwatthanawilat, Wanchai, Wiercioch, Wojtek, Sultan, Shahnaz, Rozmarinová, Jana, Drapačová, Pavla, Song, Yang, Amer, Marwa, Amer, Yasser S., Sayfi, Shahab, Verstijnen, Ilse M., Shin, Ein-Soon, Saz-Parkinson, Zuleika, Pottie, Kevin, Ruspi, Alessandra, Marušić, Ana, Saif-Ur-Rahman, K.M., Rojas, Maria X., Akl, Elie A., and Schünemann, Holger J.

Published
2024
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4. American Society of Hematology living guidelines on use of anticoagulation for thromboprophylaxis for patients with COVID-19: executive summary

Author

Siegal, Deborah M., Tseng, Eric K., Schünemann, Holger J., Angchaisuksiri, Pantep, Cuker, Adam, Dane, Kathryn, DeSancho, Maria T., Diuguid, David, Griffin, Daniel O., Klok, Frederikus A., Lee, Alfred Ian, Neumann, Ignacio, Pai, Ashok, Righini, Marc, Sanfilippo, Kristen M., Terrell, Deirdra R., Akl, Elie A., Al Jabiri, Reyad, Al Jabiri, Yazan, Barbara, Angela M., Bognanni, Antonio, Akl, Imad Bou, Boulos, Mary, Brignardello-Petersen, Romina, Chan, Matthew, Charide, Rana, Colunga-Lozano, Luis E., Dearness, Karin, Darzi, Andrea J., Hussein, Heba, Karam, Samer G., Kolb, Philipp, Mansour, Razan, Morgano, Gian Paolo, Morsi, Rami Z., Schünemann, Giovanna Muti, Nadim, Menatalla K., Noori, Atefeh, Philip, Binu A., Piggott, Thomas, Qiu, Yuan, Benitez, Yetiani Roldan, Schünemann, Finn, Stevens, Adrienne, Solo, Karla, Wiercioch, Wojtek, Mustafa, Reem A., and Nieuwlaat, Robby

Published
2024
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7. Equity issues rarely addressed in the development of COVID-19 formal recommendations and good practice statements: a cross-sectional study

Author

Dewidar, Omar, Bondok, Mostafa, Abdelrazeq, Leenah, Aliyeva, Khadija, Solo, Karla, Welch, Vivian, Brignardello-Petersen, Romina, Mathew, Joseph L., Hazlewood, Glen, Pottie, Kevin, Hartling, Lisa, Khalifa, Dina Sami, Duda, Stephanie, Falavigna, Maicon, Khabsa, Joanne, Lotfi, Tamara, Petkovic, Jennifer, Elliot, Sarah, Chi, Yuan, Parker, Roses, Kristjansson, Elizabeth, Riddle, Alison, Darzi, Andrea J., Magwood, Olivia, Saad, Ammar, Rada, Gabriel, Neumann, Ignacio, Loeb, Mark, Reveiz, Ludovic, Mertz, Dominik, Piggott, Thomas, Turgeon, Alexis F., Schünemann, Holger, and Tugwell, Peter

Published
2023
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8. American Society of Hematology living guidelines on the use of anticoagulation for thromboprophylaxis for patients with COVID-19: March 2022 update on the use of anticoagulation in critically ill patients

Author

Cuker, Adam, Tseng, Eric K., Schünemann, Holger J., Angchaisuksiri, Pantep, Blair, Clifton, Dane, Kathryn, DeSancho, Maria T., Diuguid, David, Griffin, Daniel O., Kahn, Susan R., Klok, Frederikus A., Lee, Alfred Ian, Neumann, Ignacio, Pai, Ashok, Righini, Marc, Sanfilippo, Kristen M., Siegal, Deborah M., Skara, Mike, Terrell, Deirdra R., Touri, Kamshad, Akl, Elie A., Al Jabiri, Reyad, Al Jabiri, Yazan, Boulos, Mary, Brignardello-Petersen, Romina, Charide, Rana, Colunga-Lozano, Luis E., Dearness, Karin, Darzi, Andrea J., Karam, Samer G., Morgano, Gian Paolo, Morsi, Rami Z., Philip, Binu A., Benitez, Yetiani Roldan, Stevens, Adrienne, Solo, Karla, Wiercioch, Wojtek, Mustafa, Reem A., and Nieuwlaat, Robby

Published
2022
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9. American Society of Hematology living guidelines on the use of anticoagulation for thromboprophylaxis in patients with COVID-19: January 2022 update on the use of therapeutic-intensity anticoagulation in acutely ill patients

Author

Cuker, Adam, Tseng, Eric K., Nieuwlaat, Robby, Angchaisuksiri, Pantep, Blair, Clifton, Dane, Kathryn, DeSancho, Maria T., Diuguid, David, Griffin, Daniel O., Kahn, Susan R., Klok, Frederikus A., Lee, Alfred Ian, Neumann, Ignacio, Pai, Ashok, Righini, Marc, Sanfilippo, Kristen M., Siegal, Deborah M., Skara, Mike, Terrell, Deirdra R., Touri, Kamshad, Akl, Elie A., Al Jabiri, Reyad, Al Jabiri, Yazan, Barbara, Angela M., Bognanni, Antonio, Boulos, Mary, Brignardello-Petersen, Romina, Charide, Rana, Colunga-Lozano, Luis E., Dearness, Karin, Darzi, Andrea J., Hussein, Heba, Karam, Samer G., Mansour, Razan, Morgano, Gian Paolo, Morsi, Rami Z., Muti-Schünemann, Giovanna, Nadim, Menatalla K., Philip, Binu A., Qiu, Yuan, Benitez, Yetiani Roldan, Stevens, Adrienne, Solo, Karla, Wiercioch, Wojtek, Mustafa, Reem A., and Schünemann, Holger J.

Published
2022
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10. Analytical frameworks in colorectal cancer guidelines: development of methods for systematic reviews, their application and practical guidance for their use

Author

Karam, Samer G., Darzi, Andrea J., Bognanni, Antonio, Morsi, Rami Z., Tannous, Elie E., Charide, Rana, Choe, Se-In, Stalteri, Rosa, Lee, Yung, Piggott, Thomas, Jewell, Laura, Schünemann, Finn, Langendam, Miranda, Parmelli, Elena, Saz-Parkinson, Zuleika, Roi, Annett, Vilahur, Nadia, Vali, Yasaman, Waffenschmidt, Siw, Owens, Douglas K., Leontiadis, Grigorios I., Moayyedi, Paul, Brozek, Jan L., and Schünemann, Holger J.

Published
2022
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11. American Society of Hematology living guidelines on the use of anticoagulation for thromboprophylaxis in patients with COVID-19: July 2021 update on postdischarge thromboprophylaxis

Author

Cuker, Adam, Tseng, Eric K., Nieuwlaat, Robby, Angchaisuksiri, Pantep, Blair, Clifton, Dane, Kathryn, Davila, Jennifer, DeSancho, Maria T., Diuguid, David, Griffin, Daniel O., Kahn, Susan R., Klok, Frederikus A., Lee, Alfred Ian, Neumann, Ignacio, Pai, Ashok, Righini, Marc, Sanfilippo, Kristen M., Siegal, Deborah, Skara, Mike, Terrell, Deirdra R., Touri, Kamshad, Akl, Elie A., Al Jabiri, Reyad Nayif, Al Jabiri, Yazan Nayif, Barbara, Angela M., Bognanni, Antonio, Bou Akl, Imad, Boulos, Mary, Brignardello-Petersen, Romina, Charide, Rana, Chan, Matthew, Colunga-Lozano, Luis E., Dearness, Karin, Darzi, Andrea J., Hussein, Heba, Karam, Samer G., Kolb, Philipp, Mansour, Razan, Morgano, Gian Paolo, Morsi, Rami Z., Muti-Schünemann, Giovanna, Nadim, Menatalla K., Noori, Atefeh, Philip, Binu A., Piggott, Thomas, Qiu, Yuan, Benitez, Yetiani Roldan, Schünemann, Finn, Stevens, Adrienne, Solo, Karla, Wiercioch, Wojtek, Mustafa, Reem A., and Schünemann, Holger J.

Published
2022
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12. A modeling approach to derive baseline risk estimates for GRADE recommendations: Concepts, development, and results of its application to the American Society of Hematology 2019 guidelines on prevention of venous thromboembolism in surgical hospitalized patients

Author

Morgano, Gian Paolo, Wiercioch, Wojtek, Anderson, David R., Brożek, Jan L., Santesso, Nancy, Xie, Feng, Cuker, Adam, Nieuwlaat, Robby, Akl, Elie A., Darzi, Andrea J., Yepes-Nuñez, Juan José, Exteandia-Ikobaltzeta, Itziar, Rahman, Maryam, Rajasekhar, Anita, Rogers, Frederick, Tikkinen, Kari A.O., Yates, Adolph J., Dahm, Philipp, and Schünemann, Holger J.

Published
2021
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13. American Society of Hematology living guidelines on the use of anticoagulation for thromboprophylaxis in patients with COVID-19: May 2021 update on the use of intermediate-intensity anticoagulation in critically ill patients

Author

Cuker, Adam, Tseng, Eric K., Nieuwlaat, Robby, Angchaisuksiri, Pantep, Blair, Clifton, Dane, Kathryn, Davila, Jennifer, DeSancho, Maria T., Diuguid, David, Griffin, Daniel O., Kahn, Susan R., Klok, Frederikus A., Lee, Alfred Ian, Neumann, Ignacio, Pai, Ashok, Righini, Marc, Sanfilippo, Kristen M., Siegal, Deborah, Skara, Mike, Terrell, Deirdra R., Touri, Kamshad, Akl, Elie A., Bou Akl, Imad, Bognanni, Antonio, Boulos, Mary, Brignardello-Petersen, Romina, Charide, Rana, Chan, Matthew, Dearness, Karin, Darzi, Andrea J., Kolb, Philipp, Colunga-Lozano, Luis E., Mansour, Razan, Morgano, Gian Paolo, Morsi, Rami Z., Muti-Schünemann, Giovanna, Noori, Atefeh, Philip, Binu A., Piggott, Thomas, Qiu, Yuan, Roldan, Yetiani, Schünemann, Finn, Stevens, Adrienne, Solo, Karla, Wiercioch, Wojtek, Mustafa, Reem A., and Schünemann, Holger J.

Published
2021
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15. American Society of Hematology 2021 guidelines on the use of anticoagulation for thromboprophylaxis in patients with COVID-19

Author

Cuker, Adam, Tseng, Eric K., Nieuwlaat, Robby, Angchaisuksiri, Pantep, Blair, Clifton, Dane, Kathryn, Davila, Jennifer, DeSancho, Maria T., Diuguid, David, Griffin, Daniel O., Kahn, Susan R., Klok, Frederikus A., Lee, Alfred Ian, Neumann, Ignacio, Pai, Ashok, Pai, Menaka, Righini, Marc, Sanfilippo, Kristen M., Siegal, Deborah, Skara, Mike, Touri, Kamshad, A. Akl, Elie, Bou Akl, Imad, Boulos, Mary, Brignardello-Petersen, Romina, Charide, Rana, Chan, Matthew, Dearness, Karin, Darzi, Andrea J., Kolb, Philipp, Colunga-Lozano, Luis E., Mansour, Razan, Morgano, Gian Paolo, Morsi, Rami Z., Noori, Atefeh, Piggott, Thomas, Qiu, Yuan, Roldan, Yetiani, Schünemann, Finn, Stevens, Adrienne, Solo, Karla, Ventresca, Matthew, Wiercioch, Wojtek, Mustafa, Reem A., and Schünemann, Holger J.

Published
2021
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16. Developing trustworthy recommendations as part of an urgent response (1–2 weeks): a GRADE concept paper

Author

Akl, Elie A., Morgan, Rebecca L., Rooney, Andrew A., Beverly, Brandiese, Katikireddi, Srinivasa Vittal, Agarwal, Arnav, Alper, Brian S., Alva-Diaz, Carlos, Amato, Laura, Ansari, Mohammed T., Brozek, Jan, Chu, Derek K., Dahm, Philipp, Darzi, Andrea J., Falavigna, Maicon, Gartlehner, Gerald, Pardo-Hernandez, Hector, King, Valerie, Klugarová, Jitka, Langendam, M.W. Miranda, Lockwood, Craig, Mammen, Manoj, Mathioudakis, Alexander G., McCaul, Michael, Meerpohl, Joerg J., Minozzi, Silvia, Mustafa, Reem A., Nonino, Francesco, Piggott, Thomas, Qaseem, Amir, Riva, John, Rodin, Rachel, Sekercioglu, Nigar, Skoetz, Nicole, Traversy, Gregory, Thayer, Kris, and Schünemann, Holger

Published
2021
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17. Risk-assessment models for VTE and bleeding in hospitalized medical patients: an overview of systematic reviews

Author

Darzi, Andrea J., Repp, Allen B., Spencer, Frederick A., Morsi, Rami Z., Charide, Rana, Etxeandia-Ikobaltzeta, Itziar, Bauer, Kenneth A., Burnett, Allison E., Cushman, Mary, Dentali, Francesco, Kahn, Susan R., Rezende, Suely M., Zakai, Neil A., Agarwal, Arnav, Karam, Samer G., Lotfi, Tamara, Wiercioch, Wojtek, Waziry, Reem, Iorio, Alfonso, Akl, Elie A., and Schünemann, Holger J.

Published
2020
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18. Risk models for VTE and bleeding in medical inpatients: systematic identification and expert assessment

Author

Darzi, Andrea J., Karam, Samer G., Spencer, Frederick A., Spyropoulos, Alex C., Mbuagbaw, Lawrence, Woller, Scott C., Zakai, Neil A., Streiff, Michael B., Gould, Michael K., Cushman, Mary, Charide, Rana, Etxeandia-Ikobaltzeta, Itziar, Germini, Federico, Rigoni, Marta, Agarwal, Arnav, Morsi, Rami Z., Akl, Elie A., Iorio, Alfonso, and Schünemann, Holger J.

Published
2020
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19. Prognostic factors for VTE and bleeding in hospitalized medical patients: a systematic review and meta-analysis

Author

Darzi, Andrea J., Karam, Samer G., Charide, Rana, Etxeandia-Ikobaltzeta, Itziar, Cushman, Mary, Gould, Michael K., Mbuagbaw, Lawrence, Spencer, Frederick A., Spyropoulos, Alex C., Streiff, Michael B., Woller, Scott, Zakai, Neil A., Germini, Federico, Rigoni, Marta, Agarwal, Arnav, Morsi, Rami Z., Iorio, Alfonso, Akl, Elie A., and Schünemann, Holger J.

Published
2020
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20. Individuals' Values and Preferences Regarding Medical Cannabis for Chronic Pain: A Descriptive Qualitative Study.

Author

Cummings, Hanson, Haq, Moizza Zia Ul, Dargham, Amne, Shakeel, Nauman, Busse, Jason W, Darzi, Andrea J, and Alvarez, Elizabeth

Subjects
INDIVIDUALS' preferences, MEDICAL marijuana, CHRONIC pain, MEDICAL personnel, PERCEIVED benefit
Abstract

Background: Cannabis for medical purposes has been legal in Canada since 2001; however, physicians receive no formal training in this modality, and clinical use of cannabis remains controversial. This study aims to explore the values and preferences of people living with chronic pain (PLwCP) in using medical cannabis for chronic pain to inform guideline development and shared decision-making in clinical practice.Methods: We conducted a descriptive qualitative study using in-depth interviews with PLwCP. Using a deductive/inductive approach, we developed concepts and themes related to values and preferences of PLwCP on their use (or avoidance) of medical cannabis for chronic pain.Results: We interviewed 52 PLwCP, including current medical cannabis users (40), previous users (10) and non-users (2). Most PLwCP who used cannabis therapeutically reported the need for experimentation to determine what cannabis products, routes, and doses worked for them. Perceived benefits of medical cannabis among current users included relief from pain, better sleep, and improved mental health. Reasons for discontinuing use of medical cannabis included lack of improvement in pain or sleep or undesirable side effects. Cannabidiol (CBD) dominant products were reported to result in minimal adverse effects (eg, physical or mental impairment) compared to tetrahydrocannabinol (THC) dominant products. Perceived barriers or facilitators to use included social acceptability, availability or access, cost, and attitudes and knowledge among healthcare providers. Participants noted different routes of cannabis use including oral routes that provided longer-lasting pain relief with a slower onset and inhaled routes with a more rapid onset with shorter-lived effects.Conclusion: Participants' decisions to use medical cannabis for chronic pain were varied, which suggests these decisions are likely to be sensitive to individuals' values and preferences. There is a call for further research and information-sharing to help PLwCP understand the complexities of cannabis use for medical purposes, including ideal dosing and timing.Plain Language Summary: In Canada, cannabis for medical reasons has been legal since 2001. It has been used as one of the many strategies for chronic or ongoing pain, but doctors are not given consistent information regarding its use, and existing guidance does not include the patient point of view. We did this study to explore how people living with chronic pain feel about the use of medical cannabis. We asked 52 people living with chronic pain, including current medical cannabis users, previous users, and non-users. We found that many people who used cannabis for their pain had to experiment to determine what cannabis products, routes, and doses worked for them. Benefits of medical cannabis included relief from pain, better sleep, and improved mental health. Reasons for stopping medical cannabis included no to little improvement in pain and/or sleep or the presence of unwanted side effects. Cannabidiol (CBD) products resulted in fewer unwanted effects (eg, physical or mental impairment) compared to tetrahydrocannabinol (THC) products. People discussed different routes of cannabis use including oral routes that provided longer-lasting pain relief but with a slower onset and inhaled routes with a faster onset of relief but with shorter-lived effects. People's decisions regarding medical cannabis use for chronic pain were varied, suggesting these decisions are likely to be sensitive to individual's values and preferences. More research is needed to learn what doses, products, and routes work for specific chronic pain conditions. [ABSTRACT FROM AUTHOR]

Published
2024
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21. Endovascular Thrombectomy with or without Bridging Thrombolysis in Acute Ischemic Stroke: A Cost-Effectiveness Analysis.

Author

Morsi, Rami Z., Zhang, Yuan, Zhu, Meng, Xie, Shitong, Carrión-Penagos, Julián, Desai, Harsh, Tannous, Elie, Kothari, Sachin A., Khamis, Assem, Darzi, Andrea J., Tarabichi, Ammar, Bastin, Reena, Hneiny, Layal, Thind, Sonam, Siegler, James E., Coleman, Elisheva R., Mendelson, Scott J., Mansour, Ali, Prabhakaran, Shyam, and Kass-Hout, Tareq

Subjects
ISCHEMIC stroke, ENDOVASCULAR surgery, STROKE patients, COST effectiveness, THROMBOLYTIC therapy
Abstract

Background: There is unclear added benefit of intravenous thrombolysis (IVT) with endovascular thrombectomy (EVT). We performed a cost-effectiveness analysis to assess the cost-effectiveness of comparing EVT with IVT versus EVT alone. Methods: We used a decision tree to examine the short-term costs and outcomes at 90 days after the occurrence of index stroke to compare the cost-effectiveness of EVT alone with EVT plus IVT for patients with stroke. Subsequently, we developed a Markov state transition model to assess the costs and outcomes over 1-year, 5-year, and 20-year time horizons. We estimated total and incremental cost, quality-adjusted life years (QALYs), and incremental cost-effectiveness ratio. Results: The average costs per patient were estimated to be $47,304, $49,510, $59,770, and $76,561 for EVT-only strategy and $55,482, $57,751, $68,314, and $85,611 for EVT with IVT over 90 days, 1 year, 5 years, and 20 years, respectively. The cost saving of EVT-only strategy was driven by the avoided medication costs of IVT (ranging from $8,178 to $9,050). The additional IVT led to a slight decrease in QALY estimate during the 90-day time horizon (loss of 0.002 QALY), but a small gain over 1-year and 5-year time horizons (0.011 and 0.0636 QALY). At a willingness-to-pay threshold of $50,000 per QALY gained, the probabilities of EVT only being cost-effective were 100%, 100%, and 99.3% over 90-day, 1-year, and 5-year time horizons. Conclusion: Our cost-effectiveness model suggested that EVT only may be cost-effective for patients with acute ischemic stroke secondary to large vessel occlusion. [ABSTRACT FROM AUTHOR]

Published
2024
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23. Prophylaxis against covid-19: living systematic review and network meta-analysis.

Author

Bartoszko, Jessica J., Siemieniuk, Reed A. C., Kum, Elena, Qasim, Anila, Zeraatkar, Dena, Han, Long Ge Mi Ah, Sadeghirad, Behnam, Agarwal, Arnav, Agoritsas, Thomas, Chu, Derek K., Couban, Rachel, Darzi, Andrea J., Devji, Tahira, Ghadimi, Maryam, Honarmand, Kimia, Izcovich, Ariel, Khamis, Assem, Lamontagne, Francois, Loeb, Mark, and Marcucci, Maura

Subjects
ONLINE information services, PSYCHOLOGY information storage & retrieval systems, CINAHL database, META-analysis, MEDICAL information storage & retrieval systems, MEDICAL databases, INFORMATION storage & retrieval systems, SYSTEMATIC reviews, PREVENTIVE medicine, MEDLINE
Published
2021

24. Methods used in adaptation of health-related guidelines: A systematic survey.

Author

Abdul-Khalek, Rima A., Darzi, Andrea J., Godah, Mohammad W., Kilzar, Lama, Lakis, Chantal, Agarwal, Arnav, Abou-Jaoude, Elias, Meerpohl, Joerg J., Wiercioch, Wojtek, Santesso, Nancy, Brax, Hneine, Schünemann, Holger, and Akl, Elie A.

Subjects
HEALTH planning, MEDICAL protocols, PLANNING techniques
Abstract

Background: Adaptation refers to the systematic approach for considering the endorsement or modification of recommendations produced in one setting for application in another as an alternative to de novo development.Objective: To describe and assess the methods used for adapting health-related guidelines published in peer-reviewed journals, and to assess the quality of the resulting adapted guidelines.Methods: We searched Medline and Embase up to June 2015. We assessed the method of adaptation, and the quality of included guidelines.Results: Seventy-two papers were eligible. Most adapted guidelines and their source guidelines were published by professional societies (71% and 68% respectively), and in high-income countries (83% and 85% respectively). Of the 57 adapted guidelines that reported any detail about adaptation method, 34 (60%) did not use a published adaptation method. The number (and percentage) of adapted guidelines fulfilling each of the ADAPTE steps ranged between 2 (4%) and 57 (100%). The quality of adapted guidelines was highest for the "scope and purpose" domain and lowest for the "editorial independence" domain (respective mean percentages of the maximum possible scores were 93% and 43%). The mean score for "rigor of development" was 57%.Conclusion: Most adapted guidelines published in peer-reviewed journals do not report using a published adaptation method, and their adaptation quality was variable. [ABSTRACT FROM AUTHOR]

Published
2017
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25. The Saudi clinical practice guideline for the prophylaxis of venous thromboembolism in long-distance travelers.

Author

Al-Hameed, Fahad M., Al-Dorzi, Hasan M., Abdelaal, Mohamed A., Alaklabi, Ali, Bakhsh, Ebtisam, Alomi, Yousef A., Al Baik, Mohammad, Aldahan, Salah, Schünemann, Holger, Brozek, Jan, Wiercioch, Wojtek, Darzi, Andrea J., Waziry, Reem, and Akl, Elie A.

Subjects
PHYSICIAN practice patterns, ANTIBIOTIC prophylaxis, THROMBOEMBOLISM treatment, TRAVEL hygiene, VENOUS thrombosis risk factors
Abstract

Copyright of Saudi Medical Journal is the property of Saudi Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2017
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26. The Saudi clinical practice guideline for the prophylaxis of venous thromboembolism in medical and critically ill patients.

Author

Al-Hameed, Fahad M., Al-Dorzi, Hasan M., Abdelaal, Mohamed A., Alaklabi, Ali, Bakhsh, Ebtisam, Alomi, Yousef A., Al Baik, Mohammad, Aldahan, Salah, Schünemann, Holger, Brozek, Jan, Wiercioch, Wojtek, Darzi, Andrea J., Waziry, Reem, and Akl, Elie A.

Subjects
PHYSICIAN practice patterns, PREVENTIVE medicine, THROMBOEMBOLISM treatment, THROMBOEMBOLISM, HOSPITAL care, PATIENTS
Abstract

Copyright of Saudi Medical Journal is the property of Saudi Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2016
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27. Stakeholders' perceptions of rehabilitation services for individuals living with disability: a survey study.

Author

Darzi, Andrea J., Officer, Alana, Abualghaib, Ola, and Akl, Elie A.

Subjects
*SERVICES for people with disabilities, *STAKEHOLDER theory, *INTERNET questionnaires, *LIKERT scale, *MEDICAL rehabilitation, *PSYCHOLOGY of caregivers, *HOSPITAL care, *MEDICAL personnel, *MEDICAL protocols, *PATIENT satisfaction, *PEOPLE with disabilities, *REHABILITATION centers, *RESEARCH funding, *TREATMENT effectiveness, *PSYCHOLOGY, PSYCHOLOGY of People with disabilities
Abstract

Background: The World Health Organization (WHO) was tasked with developing health system guidelines for the implementation of rehabilitation services. Stakeholders' perceptions are an essential factor to take into account in the guideline development process. The aim of this study was to assess stakeholders' perceived feasibility and acceptability of eighteen rehabilitation services and the values they attach to ten rehabilitation outcomes.Methods: We disseminated an online self-administered questionnaire through a number of international and regional organizations from the different WHO regions. Eligible individuals included persons with disability, caregivers of persons with disability, health professionals, administrators and policy makers. The answer options consisted of a 9-point Likert scale.Results: Two hundred fifty three stakeholders participated. The majority of participants were health professional (64 %). In terms of outcomes, 'Increasing access' and 'Optimizing utilization' were the top service outcomes rated as critical (i.e., 7, 8 or 9 on the Likert scale) by >70 % of respondents. 'Fewer hospital admissions', 'Decreased burden of care' and 'Increasing longevity' were the services rated as least critical (57 %, 63 % and 58 % respectively). In terms of services, 'Community based rehabilitation' and 'Home based rehabilitation' were found to be both definitely feasible and acceptable (75 % and 74 % respectively). 'Integrated and decentralized rehabilitation services' was found to be less feasible than acceptable according to stakeholders (61 % and 71 % respectively). As for 'Task shifting', most stakeholders did not appear to find task shifting as either definitely feasible or definitely acceptable (63 % and 64 % respectively).Conclusion: The majority of stakeholder's perceived 'Increasing access' and 'Optimizing utilization' as most critical amongst rehabilitation outcomes. The feasibility of the 'Integrated and decentralized rehabilitation services' was perceived to be less than their acceptability. The majority of stakeholders found 'Task shifting' as neither feasible nor acceptable. [ABSTRACT FROM AUTHOR]

Published
2016
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28. Canadian Veterans’ experiences of living with chronic pain: A descriptive qualitative study.

Author

Haq, Moizza Zia Ul, Ashoorion, Vahid, Xi, Cheng’En, Wang, Eileen, Ross, Natasha, Parakh, Nandana, Busse, Jason W., Darzi, Andrea J., and Alvarez, Elizabeth

Abstract

AbstractBackground: An estimated 30% of Veterans live with chronic pain, compared to 20% of Canadians in the general population. Veterans face healthcare challenges upon release from the military, increasing difficulties in obtaining chronic pain care.Aims: We explored experiences of Canadian Armed Forces Veterans living with chronic pain, their transition from military to civilian care, perceived barriers and facilitators to chronic pain care, and impacts of their pain on the domains of well-being.Methods: We conducted a qualitative descriptive study using semi-structured interviews. We used a deductive/inductive approach to derive themes and concepts from interview transcripts.Results: Thirty-five Veterans living with chronic pain participated. Participants reported that pain affected their lives in numerous ways, including negatively impacting relationships and limiting activities of daily living and leisure. They identified barriers to care, including lack of access to family doctors or healthcare services, reluctance to ask for help, and challenges in obtaining coverage for services from Veterans Affairs Canada. Facilitators included support from other Veterans and online resources. Chronic pain had bidirectional effects on domains of well-being.Conclusions: Experiences of pain varied amongst Canadian Veterans, and military culture played a role in perceptions and management of pain. Barriers and facilitators to chronic pain care were highlighted from their time in the military into their transition to civilian care. Participants described the impact of chronic pain on their overall well-being. Determining if these findings are relevant to a larger population of Canadian Veterans will be important for future research and knowledge translation to improve chronic pain care for Canadian Veterans. [ABSTRACT FROM AUTHOR]

Published
2024
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