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384 results on '"DERLON, A."'

4. Surgery in rare bleeding disorders: the prospective MARACHI study

Author

Rousseau, Florence, Guillet, Benoit, Mura, Thibault, Fournel, Alexandra, Volot, Fabienne, Chambost, Hervé, Suchon, Pierre, Frotscher, Brigit, Biron-Andréani, Christine, Marlu, Raphaël, Hezard, Nathalie, Clayssens, Ségolène, Boissier, Elodie, Blanc-Jouvan, Florence, Chamouni, Pierre, Tieulie, Nathalie, Rugeri, Lucia, Borel-Derlon, Annie, de Raucourt, Emmanuelle, Martin-Toutain, Isabelle, Castet, Sabine, Lebreton, Aurélien, Girault, Stéphane, Helley-Russick, Dominique, D’Oiron, Roseline, Schved, Jean-François, and Giansily-Blaizot, Muriel

Published
2023
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6. Compliance with Early Long-Term Prophylaxis Guidelines for Severe Hemophilia A

Author

Aouba, Achille, Harroche, Annie, Legrand, Faezeh, Rothschild, Chantal, Torchet, Marie-Françoise, d’Oiron, Roseline, Lambert, Thierry, Laurian, Yves, Rafowicz, Anne, Biernat, Jennifer, Goudemand, Jenny, Parquet, Armelle, Tintillier, Véronique, Wibaut, Bénédicte, Assollant, Anne Durin, Meunier, Sandrine, Négrier, Claude, Castet, Sabine, Guérin, Viviane, Huguenin, Yohann, Micheau, Marguerite, Ryman, Anne, Chambost, Hérve, Falaise, Céline, Claeyssens, Ségolène, Thiercelin-Legrand, Marie Françoise, Fiks-Sigaud, Marianne, Fouassier, Marc, Fressinaud, Edith, Trossaert, Marc, Voisin, Sophie, Faradji, Albert, Lutz, Patrick, Briquel, Marie Elisabeth, Frotscher, Birgit, Fimbel, Béatrice, Gruel, Yves, Guerois, Claude, Regina, Sandra, Valentin, Jean Baptiste, Biron Andreani, Christine, Codine, Philippe, Donadio, Daniel, Navarro, Robert, Rospide, Paola, Schved, Jean-François, Berger, Claire, Collet, Bénédicte, Derlon, Annie Borel, Gautier, Philippe, Bayart, Sophie, Guillet, Ben⊚ıt, Borg, JeanneYvonne, Dumesnil, Cécile, Normand, Charline, Schneider, Pascale, Tron, Philippe, Vannier, Jean-Pierre, Dutrillaux, Fabienne, Volot, Fabienne, Gembara, Piotr, Marques-Verdier, Alain, Adjaoud, Dalila, Barro, Claire, Pernod, Gilles, Polack, Ben⊚ıt, Pouzol, Patricia, Ounnoughene, Nadra, Paugy, Patricia, Robert, Valérie, Stieltjes, Natalie, Bastenaire, Brigitte, de Raucourt, Emmanuelle, Peynet, Jocelyne, Li-Thiao-Te, Valérie, Pautard, Brigitte, Behar, Catherine, Gorde, Stéphanie, Munzer, Martine, Gay, Valérie, Benz Lemoine, Elisabeth, Macchi, Laurent, De Lumley, Lionel, Gaillard, Solange, Oudot, Caroline, Deville, Anne, Monpoux, Fabrice, Bertrand, Marie Anne, Pan-Petesch, Brigitte, Hassoun, Abel, Coatmelec, Brigitte, Beurrier, Philippe, Damay, Michèle, Moreau, Philippe, Pouille-Lievin, Odile, Schoepfer, Caroline, Tarral, Eliane, Bianchin, Monique, Nguyen, Joël, Pincemaille, Olivier, Peter, Marie-Odile, Saultier, Paul, Guillaume, Yves, Demiguel, Virginie, Borel-Derlon, Annie, Vinciguerra, Christine, Boucekine, Mohamed, Baumstarck, Karine, Calvez, Thierry, and Chambost, Hervé

Published
2021
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9. P1672: OCCUPATIONAL INTEGRATION OF ADULTS WITH SEVERE HAEMOPHILIA (INTHEMO): A STUDY BASED ON THE FRANCECOAG REGISTRY

Author

Ngoc Anh Thu Nguyen, Pascal Auquier, Any Beltran Anzola, Roseline D’oiron, Thierry Lambert, Céline Falaise, Christine Biron, Anne Lienhart, Jenny Goudemand, Antoine Rauch, Bénédicte Wibaut, Sabine Marie Castet, Dominique Desprez, Annie Harroche, Natalie Stieltjes, Annie Borel-Derlon, Marc Trossaërt, Amandine Celli, Benoît Guillet, Sophie Bayart, Marie-Anne Bertrand, Alexandra Fournel, Guillaume Mourey, Valérie Gay, Pierre Chamouni, Emmanuelle DE Raucourt, Birgit Frotscher, Michèle Martin, Mathieu Puyade, Brigitte Tardy, Stéphane Vanderbecken, Fabienne Genre-Volot, Philippe Nguyen, Benoît Polack, Caroline Oudot-Challard, Stéphane Girault, Annelise Voyer, Aurélien Lebreton, Abel Hassoun, Philippe Moreau, Pierre-Simon Rohrlich, Karine Baumstarck, Mohamed Boucekine, Vanessa Milien, Natacha Rosso, Clemence Tabele, Marie Viprey, Nicolas Giraud, Thomas Sannie, Hervé Chambost, and Noémie Resseguier

Subjects
Diseases of the blood and blood-forming organs, RC633-647.5
Published
2023
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11. Modelling of aerobic granular sludge reactors: the importance of hydrodynamic regimes, selective sludge removal and gradients

Author

Nicolas Derlon, Mercedes Garcia Villodres, Róbert Kovács, Antoine Brison, Manuel Layer, Imre Takács, and Eberhard Morgenroth

Subjects
aerobic granular sludge, gradients over reactor height, hydraulic selection, modelling, plug-flow feeding, Environmental technology. Sanitary engineering, TD1-1066
Abstract

Hydraulic selection is a key feature of aerobic granular sludge (AGS) systems but existing aerobic granular sludge (AGS) models neglect those mechanisms: gradients over reactor height (Hreactor), selective removal of slow settling sludge, etc. This study aimed at evaluating to what extent integration of those additional processes into AGS models is needed, i.e., at demonstrating that model predictions (biomass inventory, microbial activities and effluent quality) are affected by such additional model complexity. We therefore developed a new AGS model that includes key features of full-scale AGS systems: fill-draw operation, selective sludge removal, distinct settling models for flocs/granules. We then compared predictions of our model to those of a fully mixed AGS model. Our results demonstrate that hydraulic selection can be predicted with an assembly of four continuous stirred tank reactors in series together with a correction code for plug-flow. Concentration gradients over the reactor height during settling/plug-flow feeding strongly impact the predictions of aerobic granular sludge models in terms of microbial selection, microbial activities and ultimately effluent quality. Hydraulic selection is a key to predict selection of storing microorganisms (phosphorus-accumulating organisms (PAO) and glycogen-accumulating organisms (GAO)) and in turn effluent quality in terms of total phosphorus, and for predicting effluent solid concentration and dynamic during plug-flow feeding. HIGHLIGHTS New model for aerobic granular sludge system developed.; Hydraulic selection of granules (bed stratification, plug flow feeding, etc.) are included.; Gradients over reactor height predicted with a series of four CSTRs plus plug-flow correction code.; Concentration gradients over Hreactor strongly impact predictions in terms of microbial selection, microbial activities and effluent quality.;

Published
2022
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12. Synthetic periphyton as a model system to understand species dynamics in complex microbial freshwater communities

Author

Olga Lamprecht, Bettina Wagner, Nicolas Derlon, and Ahmed Tlili

Subjects
Microbial ecology, QR100-130
Abstract

Abstract Phototrophic biofilms, also known as periphyton, are microbial freshwater communities that drive crucial ecological processes in streams and lakes. Gaining a deep mechanistic understanding of the biological processes occurring in natural periphyton remains challenging due to the high complexity and variability of such communities. To address this challenge, we rationally developed a workflow to construct a synthetic community by co-culturing 26 phototrophic species (i.e., diatoms, green algae, and cyanobacteria) that were inoculated in a successional sequence to create a periphytic biofilm on glass slides. We show that this community is diverse, stable, and highly reproducible in terms of microbial composition, function, and 3D spatial structure of the biofilm. We also demonstrate the ability to monitor microbial dynamics at the single species level during periphyton development and how their abundances are impacted by stressors such as increased temperature and a herbicide, singly and in combination. Overall, such a synthetic periphyton, grown under controlled conditions, can be used as a model system for theory testing through targeted manipulation.

Published
2022
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17. Prevention of venous thromboembolism and haemostasis monitoring in patients with COVID-19: Updated proposals (April 2021): From the French working group on perioperative haemostasis (GIHP) and the French study group on thrombosis and haemostasis (GFHT), in collaboration with the French society of anaesthesia and intensive care (SFAR)

Author

Albaladejo, P., Blais, N., Bonhomme, F., Borel-Derlon, A., Cohen, A., Collet, J.-P., de Maistre, E., Fontana, P., Garrigue Huet, D., Godier, A., Gruel, Y., Godon, A., Ickx, B., Laporte, S., Lasne, D., Llau, J., Le Gal, G., Lecompte, T., Lessire, S., Levy, J.H., Longrois, D., Madi-Jebara, S., Mansour, A., Mazighi, M., Mismetti, P., Morange, P.E., Motte, S., Mullier, F., Nathan, N., Nguyen, P., Pernod, G., Rosencher, N., Roullet, S., Roy, P.M., Schlumberger, S., Sié, P., Steib, A., Susen, S., Tacquard, C.A., Testa, S., Vincentelli, A., Zufferey, P., Boissier, E, Dumont, B, James, C, Siguret, V., Godon, Alexandre, Tacquard, Charles Ambroise, Mansour, Alexandre, Garrigue, Delphine, Nguyen, Philippe, Lasne, Dominique, Testa, Sophie, Levy, Jerrold H., Albaladejo, Pierre, Gruel, Yves, Susen, Sophie, and Godier, Anne

Published
2021
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18. Impact of High-Dose Prophylactic Anticoagulation in Critically Ill Patients With COVID-19 Pneumonia

Author

Albaladejo, P., Blais, N., Bonhomme, F., Borel-Derlon, A., Cohen, A., Collet, J.-P., de Maistre, E., Fontana, P., Garrigue Huet, D., Godier, A., Gruel, Y., Godon, A., Ickx, B., Laporte, S., Lasne, D., Llau, J., Le Gal, G., Lecompte, T., Lessire, S., Levy, J.H., Longrois, D., Madi-Jebara, S., Mansour, A., Mazighi, M., Mismetti, P., Morange, P.E., Motte, S., Mullier, F., Nathan, N., Nguyen, P., Pernod, G., Rosencher, N., Roullet, S., Roy, P.M., Schlumberger, S., Sié, P., Steib, A., Susen, S., Tacquard, C.A., Testa, S., Vincentelli, A., Zufferey, P., Tacquard, Charles, Mansour, Alexandre, Godon, Alexandre, Godet, Julien, Poissy, Julien, Garrigue, Delphine, Kipnis, Eric, Rym Hamada, Sophie, Mertes, Paul Michel, Steib, Annick, Ulliel-Roche, Mathilde, Bouhemad, Bélaïd, Nguyen, Maxime, Reizine, Florian, Gouin-Thibault, Isabelle, Besse, Marie Charlotte, Collercandy, Nived, Mankikian, Stefan, Levy, Jerrold H., Gruel, Yves, Albaladejo, Pierre, Susen, Sophie, and Godier, Anne

Published
2021
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26. Diagnosis and management of heparin-induced thrombocytopenia

Author

Albaladejo, P., Belisle, S., Blais, N., Bonhomme, F., Borel-Derlon, A., Borg, J.Y., Bosson, J.-L., Cohen, A., Collet, J.-P., de Maistre, E., Faraoni, D., Fontana, P., Huet, D. Garrigue, Godier, A., Gruel, Y., Guay, J., Hardy, J.F., Huet, Y., Ickx, B., Laporte, S., Lasne, D., Levy, J.H., Llau, J., Le Gal, G., Lecompte, T., Lessire, S., Longrois, D., Madi-Jebara, S., Marret, E., Mas, J.L., Mazighi, M., Meyer, G., Mismetti, P., Morange, P.E., Motte, S., Mullier, F., Nathan, N., Nguyen, P., Ozier, Y., Pernod, G., Rosencher, N., Roullet, S., Roy, P.M., Samama, C.M., Schlumberger, S., Schved, J.F., Sié, P., Steib, A., Susen, S., Testa, S., van Belle, E., van Der Linden, P., Vincentelli, A., Zufferey, P., Gruel, Yves, De Maistre, Emmanuel, Pouplard, Claire, Mullier, François, Susen, Sophie, Roullet, Stéphanie, Blais, Normand, Le Gal, Grégoire, Vincentelli, André, Lasne, Dominique, Lecompte, Thomas, Albaladejo, Pierre, and Godier, Anne

Published
2020
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27. EPIdemiology of Surgery-Associated Acute Kidney Injury (EPIS-AKI): study protocol for a multicentre, observational trial

Author

Melanie Meersch, Mira Küllmar, Carola Wempe, Alexander Zarbock, Ke Peng, Sigismond Lasocki, Thomas Rimmele, Maria Martin, Olivier Desebbe, Michele Rossi, Matthias Heringlake, Christina Massoth, Raphael Weiss, Andreas Höhn, Gael Pradel, Ana Kowark, Ahmed mohamed Ibrahim, Orestis Ioannidis, Andrea Cortegiani, Maxime Leger, Emmanuel Rineau, Pierre-Yves Egreteau, Andrea Russo, Laura Kerschke, Savino Spadaro, Carole Ichai, Vincent Cottenceau, Sebastian Ziemann, Maria Gomez, Julien Nadaud, Olivier Pérus, Philippe Magazzeni, Philippe Montravers, Deniz Karakaya, Christophe Aveline, Alexander Bentley, Tulay Ozkan Seyhan, Jean-François Pittet, Sébastien Ponsonnard, Pierre Garcon, Ana Serrano, Gulay Ok, Pierre Vautier, Jean François Gautier, Sergi Sabaté, Yusuf Tunali, Valérie Cerro, Stephanie Suria, Khaschayar Saadat-Gilani, Hichem Makhloufi, Anis Cherak, Lamine Lakhel Ghanem, Zohier Gouaglia, Dina Nasrine Guadouri, Fayrouz Naouel Hama, Mustafa Kara, Omayma Saadi, Rachida Sakhraoui, Fadila Bourou, Abdelhadi Cherifi, Rahmoune Ghania Sadaoui, Amel Ouyahia, Ilhem Ouahab, Souad Bouaoud, Meriem Abdoun, Anisse Tidjane, Benali Tabeti, Nabil Boudjenan-Serradj, Carlos Jose Pérez Rivera, Paulo Cabrer, Julián Corso, Juan Pablo García, Sharon Idarraga, Christopher Montoya, Rafael Figueroa, Eduar Aldana, María Alejandra Torrado, Zheng-min Ma, Yu-fan Yang, Ya-juan Zhu, Peter Sklienka, Michal Frelich, Vojtech Jarkulis, Pavel Sevcik, Vojtech Vodicka, Mohamed Gamal Elbahnasawy, Shady Elsalhawy, Sara Motawea, Zeinab Othman, Mohamed Sahma, Ahmed Mahmoud Nafea, Nermin Ahmed, Doaa Ali Attia, Moataz Maher Emara, Mohamed Mamdouh Bonna, Mohamed Ahmed Gabr, Amany Ismail Tarbay, Ibrahim Abdelmonaem Abdehaleem, Esraa Elsayed Mohamed, Amr Mahmoud Eldeeb, Ahmed Mohamed Abbas, John Ashraf Magdy, Zyad Hassan Hamed, Hany Mostafa Esmaeil Osman, Mostafa Samy Abbas, Oliver Joannes-Boyau, Nicolas Barraud, Corentin Berthelot, Thibault Camus, Anissa Dahmi, Mylène Defaye, Sébastien Derville, Younes El-Boustani, Elsa Deloge, Hélène Jacob, Simon Monziols, Fred Priem, Jean-Jacques Robin, Vincent Legros, Therry Floch, Salvatore Muccio, Claire Geneve, Marie Lim Legouge, Stéphanie Tao Mauny, Willy Mfam, Léa Pascot, Mireille Chartier, Benjamin Duteurtre, Aidren Le Cousin, Nathalie Begel, Claire-Annissa Chekirine, Vincent Derlon, Elodie Grein, Marie-Annick Lehair, Laurent Magazzeni, Carsten Potter, Catherine Roth, Florence Voivret, Jamil Elmawieh, Annabelle Stoclin, Cédric Cirenei, Gregoire Andrieu, Sven Couloumy, Jeremy Falcone, Marion Fajardy, Arsène Gagneuil, Emeline Girardet, Agnès Mazereeuw, Mélanie Bertel, Simon Bocher, Vanessa Carn, Lenaïg Le Guen, Guillaume Le Loup, Montaine Lefevre, Amanita Diop, Vanessa Jean-Michel, Sylvie Devlieger, Juliette Duthoit, Mohamed El Kadiri, Viviane Cassisa, Charline Masson, Pierre Verrier, Axel Coquerel, Enora Atchade, Charles-Edouard Rochon, Céline Delerue, Vidal Quentin, Vanessa Latry, Nina Queixalos, Thierry Braun, Saad Bouzoubaa, Basile Christ, Audrey Geiger, Joachim Gomille, Vianney Kieffer, Simone Mangeant, Christelle Prochilo, Christian Schmitt, Stefan Skwirba, Hubert Grand, Frédérique Boury, Nicolas Mayeur, Marie Pasquie, Vincent Bruckert, Vincent Arnould, Mona Bonciu, Thibault Chapelle, Luc Facchino, Florence Fagot-Gandet, Andrea Iachim, Elena Mannu, Rémi Plattier, Romain Rozier, Michel Boudinaud, Marie-Hélène Hausermann, My Hue Nguyen, Andersen Ramorasata, Amélie Barreau, Anne-Hélène Boivin, Céline Ravry, Nicolas Mottard, Johanne Beuvelot, Florence Prunier Bossion, Christian Dörr, Thilo Caspar von Groote, Linda Grüßer, Pia Wittig, Timo Brandenburger, Thomas Dimski, Niklas Döhmen, Laura Huthmann, Daniela Kaierle, Claude Pelletier, Manon Schleß, Sebastian Cleophas, Stephanie Haunhorst, Marina Jansen, Alexandra Schmitt, Julia Soisch, Kilian Sturm, Peter Rosenberger, Alexander Bendig, Lena Flohr, Helene Häberle, Pascal Hofmann, Jonathan Kuhle, Nora Michaela Leser, Kathrin Pfister, Stefanie Prohaska, Franziska Sennholz, Lena Stetz, Kathrin Weber, Sebastian Stehr, Stephan Klaus, Marco Sadlo, Matthias Boschin, Christian Sengelhoff, Ulrich Michael Göbel, Jan Gerrit Haaker, Carina-Kristin Göttker, Matthias Gründel, Romina Baumgärtel, Astrid Berggren, Madeleine Gülzow, Lennart Muras, Hauke Paarmann, Serge Thal, Dschamil El-Masri, Eleni Arnaoutoglou, Maria Ntalouka, Paula Stratigopoulou, Anastasia Analytis, Efthymios Mavrommatis, Petros Tzimas, Agathi Karakosta, Danai Pantazi, Antonia Dimakopoulou, Katerina Dimitropoulou, Humam Jalaawiy, Aeshah Anwar, Hashim Talib Hashim, Hogir Imad Rasheed Aldawoody, Giulia Catalisano, Gilia Ingoglia, Mariachiara Ippolito, Silvia De Rosa, Lucia Cattin, Andrea Bianchin, Marisa Barone, Gianluca Paternoster, Salvatore Lucio Cutuli, Liliana Sollazzi, Laura Cascarano, Massimo Antonelli, Paola Aceto, Bruno Romanò, Vincenzo Francesco Tripodi, Rosamaria Scappatura, Maria Cristina Vadalà, Diego Fiume, Maria Teresa Strano, Giulia Oddo, Clemente Santorsola, Bilal Abu Hussain, Adnan Raed Alnaser, Anas Hassouneh Ghassan, Khaled Hasanein, Mohammed Theab, Seokyung Shin, Seungho Jung, Kyuho Lee, Sung Mee Jung, Jongyoon Baek, Muhammed K. Elhadi, Issa Abuzeid, Mohammed Albaraesi, Sarah Aldressi, Wegdan Khalel, Eman Abdulwahed, Akram Abdulhamid Ashur Abujrad, Amer Almaghrabi, Muhand Mohammed Alteleeb, Entisar Ahmed Ali Alshareea, Marwa Isa Biala, Abdulqudus Deeknah, Dooua Ali Gheddim, Reem Ghmagh, Nawras Salih Ali AbuIkhrays, Marwa Sinan, Enas Soula, Sumayyah Ghayth Bahroun, Khawla Derwish, Aya Munir Mohamed, Eman Sayed Younes, Rayet Al Islam Benjouira, Mohamed Aliwa, Najwa Abdullah Altashani, Mohammed Omar Alteb, Ahmed Msherghi, Fatima Alagelli, Sufyan Albarouni, Ahmed Albishti, Sarah Aljamal, Mohamed Alsori, Taha Ekhuja, Suha Elzwai, Mohammed Ghula, Tahani Mustafa, Ahmed Tuwaib, Haifa Zriba, Hamza Mahmoud Agilla, Toky Andriamahefa Rafanomezantsoa, Anne Marie Camilleri Podesta, Denise Mifsud Bonnici, Tiziana Pirotta, Gilberto Adrián Gasca López, Maja Mojsova Mijovska, Tatjana Davitkovska, Aleksandra Gavrilovska, Sanja Lukikj, Marija Vesova, Dina Zafirova, Sarah Amro, Baraa N. F. Hajjaj, Muawia Alkhazendar, Yousuf Barakat, Sewar Abdulaziz Elejla, Ahmed Elhissi, Ahmed Khader, Ali Salem, Rita de Freitas Regufe, André Filipe de Oliveira Eloy, Lisbete Marisa Neto Cordeiro Perdigão, Evgeny Grigoriev, Artem Ivkin, Roman Kornelyuk, Michael Yaroustovsky, Marina Abramyan, Ekaterina Komardina, Nataliya Lesteva, Medina Aybazova, Elmira Kumykova, Svetlana Lesina, Gennady Rybakov, Alexey Shestov, Abdulnaser Ahmad Ahmad Barmou, Bushra Lotfi Altayeb Ahmed, Aisha Mohammad Eliyas, Yousra Emadeldin, Alexander Kaserer, Clara Castellucci, Julian Rössler, Samira Akbas, Andreja Möller Petrun, Irena Gregorcic, Vesna Sok, Roman Čičak, Elizabeth Bárcena, Antonio Guisado, Ismail Wi, Javier Ripollés Melchor, Ángel Becerra-Bolaños, Sergio Cabrera-Doreste, Ancor Domínguez-Arbelo, María Candelaria Delgado-Alonso, Virginia Muiño-Palomar, Aurelio Rodríguez-Pérez, Javier Mata Estévez, Maria Begona Covas Munoz, Juan Mulet Matas, Sara Perez Palao, Maria Dolores Mira Quirós, Alisia Cezara Teslev, Mercedes Garcia Alvarez, Marga Argilaga, María Campos, Albert Bainac, Astrid Batalla, Marta Giné, Gracia Herránz, Ignacio Hinojal, Margarita Logroño Ejea, Noelia de la Rosa Ruiz, María Gastaca Abasolo, Carla Rosario Houhton Acuna, Ibai Iriarte Zaranton, Ana Mendigurenmurua, María José Munoz Sanz, Erika Olea de la Fuente, María Pilar Pérez Vaquero, Ana Soto Iglesias, Ana Ugarte Mieres, Alaitz Urtiaga Urrestizala, Lourdes Ferreira, Félix Lobato, Marta Aguado Sevilla, Andres Erazo, Pere Miró, Diana Vernetta, Berta Castellano Paulis, Anabel Adell Perez, Marta Aseguinolaza Pagola, Elena delVal Peciña, Ainhoa Garmendia Odriozola, Amaia Lopetegi Aizpurua, Olatz Pavón Piquer, Pilar Plou Garcia, Paula Ortega Rezola, Antia Osorio Lopez, Isabel de la Calle Gil, Rosalía Navarro Casado, Peter Adamove, Roser Bayona Domenge, Francho Miguel Blasco Blasco, Adriana Alexandra Rueda Villamizar, Maria Antonia Perelló Llaneras, Jose Ignacio García-Sánchez, Laura Fernandez Téllez, Sara García Zamorano, Natalia Gijón Herreros, Andrea Rodriguez Esteve, Pablo Monedero Rodríguez, Isabel García Trigo, Agustín Alcaraz, Andrea Lara Jiménez, Iñigo Rubio, Nuria García, Raquel Callejas, Angel Manuel Candela Toha, Eli Claros, Pilar Cobeta, Pascual Crespo, Trini Dorado, Elena Elías, Javier Felices, Diego Gil, Nuria Mané, Adolfo Martínez, Lucía Pereira, Alberto Balvis Noemí Samaranch, Carlos Tiscar, Judith VillaHoz, Patricia Galán Menéndez, Elena Cardona, Anna Conesa, Veronica Estepa, Laura Llinares Espí, Yuri Loaiza Aldeán, Susana Manrique, Víctor Morales Ariza, Laura Villarino Villa, Elfayadh Saidahmed Mohamed Amed Suliman, Hytham Hamid, Modather Mohamed Saeed, Orhan Sungur Mukadder, Demet Altun, Nur Canbolat, Müşerref Beril Dinçer, Serap Aktaş Yıldırım, Müzeyyen İyigün, Davut Yapıcı, Levent Özdemir, Aslinur Sagun, Neval Boztug, Yesim Cetintas, Bora Dinc, Emel Gündüz, Hakkı Ünlügenç, Demet Lafli Tunay, Ozgur Komurcu, Özlem Korkmaz Dilmen, Eren Fatma Akcil, Eda Tok Alsina, Özge Hakli, Cengiz Polat, Namigar Turgut, Nurcan Kızılcık, Özge Köner, Öznur Şen, Nurdan Aydin, Burcu Basaran, Emre Sertac Bingul, Kamil Darcin, Semra Ugur, Kemal Tolga Saracoglu, Asli Demir, Özgök Aysegül, Eda Balci, Behic Girgin, Aygun Guler, Ümit Karadeniz, Nihal Özaslan, Yigit Özay Hülya, Namik Ozcan, Aysun Postaci, Mehmet Sahap, Nevriye Salman, Özlem Sağır, Bulent Atik, Murat Bicakcioglu, Hafize Fisun Demir, Ugün Fatih, Nazan Kocaoglu, Hüseyin ilksen Toprak, Duygu Demiröz Aslan, Yusuf Ziya Colak, Mustafa Soner Ozcan, Mehmet Yilmaz, Umran Karaca, Sevtap Hekimoglu Sahin, Özlem Ersoy Karka, Gizem Demir Şenoğlu, Süheyla Erkoç Karadağ, Neslihan Alkis, Volkan Baytaş, Engin Erturk, Ali Akdogan, Ahmet Besir, Dilek Kutanis, Sedat Saylan, Ersagun Tugcugil, Pinar Ayvat, Berrin Günaydın, Beyza Mehri Büyükgebiz, Omer Faruk Boran, Feyza Calisir, Yavuz Orak, Bahar Kuvaki Balkan, Sibel Büyükcoban, Erol Gökel, Sakize Ferim Günenc, Sule Özbilgin, Suna Göre, Selcan Akesen, Seda Cansabuncu, Natalia Momot, Anna Panchenko, and Kristen Rutledge

Subjects
Medicine
Abstract

Introduction More than 300 million surgical procedures are performed each year. Acute kidney injury (AKI) is a common complication after major surgery and is associated with adverse short-term and long-term outcomes. However, there is a large variation in the incidence of reported AKI rates. The establishment of an accurate epidemiology of surgery-associated AKI is important for healthcare policy, quality initiatives, clinical trials, as well as for improving guidelines. The objective of the Epidemiology of Surgery-associated Acute Kidney Injury (EPIS-AKI) trial is to prospectively evaluate the epidemiology of AKI after major surgery using the latest Kidney Disease: Improving Global Outcomes (KDIGO) consensus definition of AKI.Methods and analysis EPIS-AKI is an international prospective, observational, multicentre cohort study including 10 000 patients undergoing major surgery who are subsequently admitted to the ICU or a similar high dependency unit. The primary endpoint is the incidence of AKI within 72 hours after surgery according to the KDIGO criteria. Secondary endpoints include use of renal replacement therapy (RRT), mortality during ICU and hospital stay, length of ICU and hospital stay and major adverse kidney events (combined endpoint consisting of persistent renal dysfunction, RRT and mortality) at day 90. Further, we will evaluate preoperative and intraoperative risk factors affecting the incidence of postoperative AKI. In an add-on analysis, we will assess urinary biomarkers for early detection of AKI.Ethics and dissemination EPIS-AKI has been approved by the leading Ethics Committee of the Medical Council North Rhine-Westphalia, of the Westphalian Wilhelms-University Münster and the corresponding Ethics Committee at each participating site. Results will be disseminated widely and published in peer-reviewed journals, presented at conferences and used to design further AKI-related trials.Trial registration number NCT04165369.

Published
2021
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28. Detection of Gel-Forming Polymers via Calcium Crosslinking, Applied to the Screening of Extracellular Polymeric Substances Extracted from Biological Aggregates

Author

Abdo Bou-Sarkis, Etienne Paul, Elisabeth Girbal-Neuhauser, Nicolas Derlon, and Yolaine Bessiere

Subjects
hydrogels, gelling capacity, calcium crosslinking, aerobic granules, alginate-like exopolymers, extracellular polymeric substances, Science, Chemistry, QD1-999, Inorganic chemistry, QD146-197, General. Including alchemy, QD1-65
Abstract

The valorization of biological aggregates through the extraction of hydrogel-forming polymers can enhance the economics and sustainability of various processes in which bacteria are involved in organic waste transformation, such as wastewater treatment. Achieving these goals requires the development of a method capable of detecting the presence of gel-forming polymers in complex mixtures containing biopolymers that are most often unknown and uncharacterized. A miniaturized screening method capable of detecting gelation via ionic crosslinking using only 1 to 3 mg of the tested samples (commercial molecules or extracellular polymeric substances, EPSs) is proposed. The method consists of calculating a percentage of reactivity (%R) through UV-vis spectra and determining the percentage of gel volume (%Vg) formed after the addition of calcium. Both factors were combined to give a gelling factor (GF), and the test was applied to pure commercial molecules (BSA, DNA, alginate (ALV), and a mixture of them), allowing the classification of the following solutions according to their gel-forming capacity: GF(ALV) > GF(ALV+DNA) > GF(BSA+ALV+DNA) > GF(BSA+ALV) > GF(DNA) > GF(BSA+DNA) > GF(BSA). As a relevant tool for screening hydrogel-forming solutions, the method was applied to the EPS extracted from aerobic granular sludge. The EPS (0.5% w/v) had a GF of 0.16 ± 0.03, equivalent to approximately half of the GF of ALV (0.38 ± 0.02 at 0.5% w/v). The developed test pushes the limits of the existing gel-detection techniques because it allows for quicker, less consuming, and more informative gelation detection through the use of simple methods that do not require sophisticated equipment.

Published
2023
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32. Gestion des agents antiplaquettaires en cas de procédure invasive non programmée ou d’hémorragie. Propositions du Groupe d’intérêt en hémostase périopératoire (GIHP) et du Groupe français d’études sur l’hémostase et la thrombose (GFHT) en collaboration avec la Société française d’anesthésie et de réanimation (SFAR)

Author

Belisle, S., Blais, N., Borel-Derlon, A., Borg, J.Y., Bosson, J.-L., Cohen, A., Faraoni, D., Garrigue Huet, D., Guay, J., Hardy, J.F., Huet, Y., Laporte, S., Levy, J.H., Llau, J., Le Gal, G., Lessire, S., Longrois, D., Madi-Jebara, S., Marret, E., Mas, J.L., Meyer, G., Mismetti, P., Morange, P.E., Motte, S., Mullier, F., Nathan, N., Ozier, Y., Pernod, G., Rosencher, N., Roullet, S., Roy, P.M., Samama, C.M., Schlumberger, S., Schved, J.F., Sié, P., Steib, A., Susen, S., van Belle, E., van Der Linden, P., Zufferey, P., Godier, Anne, Garrigue, Delphine, Lasne, Dominique, Fontana, Pierre, Bonhomme, Fanny, Collet, Jean-Philippe, de Maistre, Emmanuel, Ickx, Brigitte, Gruel, Yves, Mazighi, Mikael, Nguyen, Philippe, Vincentelli, André, Albaladejo, Pierre, and Lecompte, Thomas

Published
2019
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36. Position du GIHP sur les tests viscoélastiques : quelle place pour quelle indication en situation hémorragique ?

Author

Albaladejo, Pierre, Belisle, Sylvain, Blais, Normand, Bonhomme, Fanny, Borel-Derlon, Annie, Borg, Jeanne-Yvonne, Bosson, Jean-Luc, Cohen, Ariel, Collet, Jean-Philippe, de Maistre, Emmanuel, Faraoni, David, Fontana, Pierre, Garrigue Huet, Delphine, Godier, Anne, Gruel, Yves, Guay, Joanne, Hardy, Jean-François, Huet, Yann, Ickx, Brigitte, Laporte, Silvy, Lasne, Dominique, Levy, Jerrold H., Llau, Juan, Le Gal, Grégoire, Lecompte, Thomas, Lessire, Sarah, Longrois, Dan, Madi-Jebara, Samia, Marret, Emmanuel, Mas, Jean-Louis, Mazighi, Mikael, Mismetti, Patrick, Morange, Pierre-Emmanuel, Motte, Serge, Mullier, François, Nathan, Nathalie, Nguyen, Philippe, Ozier, Yves, Pernod, Gilles, Rosencher, Nadia, Roullet, Stéphanie, Roy, Pierre-Marie, Samama, Charles Marc, Schlumberger, Sylvie, Schved, Jean-François, Sié, Pierre, Steib, Annick, Susen, Sophie, van Belle, Eric, Van der Linden, Philippe, Vincentelli, André, Zufferey, Paul, and Garrigue, Delphine

Published
2018
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38. Management of antiplatelet therapy in patients undergoing elective invasive procedures. Proposals from the French Working Group on perioperative haemostasis (GIHP) and the French Study Group on thrombosis and haemostasis (GFHT). In collaboration with the French Society for Anaesthesia and Intensive Care Medicine (SFAR)

Author

Albaladejo, P., Belisle, S., Blais, N., Bonhomme, F., Borel-Derlon, A., Borg, J.Y., Bosson, J.-L., Cohen, A., Collet, J.-P., de Maistre, E., Faraoni, D., Fontana, P., Garrigue Huet, D., Godier, A., Gruel, Y., Guay, J., Hardy, J.F., Huet, Y., Ickx, B., Laporte, S., Lasne, D., Levy, J.H., Llau, J., Le Gal, G., Lecompte, T., Lessire, S., Longrois, D., Madi-Jebara, S., Marret, E., Mas, J.L., Mazighi, M., Mismetti, P., Morange, P.E., Motte, S., Mullier, F., Nathan, N., Nguyen, P., Ozier, Y., Pernod, G., Rosencher, N., Roullet, S., Roy, P.M., Samama, C.M., Schlumberger, S., Schved, J.F., Sié, P., Steib, A., Susen, S., van Belle, E., van Der Linden, P., Vincentelli, A., Zufferey, P., Godier, Anne, Fontana, Pierre, Motte, Serge, Steib, Annick, Bonhomme, Fanny, Schlumberger, Sylvie, Lecompte, Thomas, Rosencher, Nadia, Susen, Sophie, Vincentelli, André, Gruel, Yves, Albaladejo, Pierre, and Collet, Jean-Philippe

Published
2018
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41. Management of antiplatelet therapy in patients undergoing elective invasive procedures: Proposals from the French Working Group on perioperative hemostasis (GIHP) and the French Study Group on thrombosis and hemostasis (GFHT). In collaboration with the French Society for Anesthesia and Intensive Care (SFAR)

Author

Albaladejo, P., Belisle, S., Blais, N., Bonhomme, F., Borel-Derlon, A., Borg, J.Y., Bosson, J.-L., Cohen, A., Collet, J.-P., de Maistre, E., Faraoni, D., Fontana, P., Garrigue Huet, D., Godier, A., Gruel, Y., Guay, J., Hardy, J.F., Huet, Y., Ickx, B., Laporte, S., Lasne, D., Levy, J.H., Llau, J., Le Gal, G., Lecompte, T., Lessire, S., Longrois, D., Madi-Jebara, S., Marret, E., Mas, J.L., Mazighi, M., Mismetti, P., Morange, P.E., Motte, S., Mullier, F., Nathan, N., Nguyen, P., Ozier, Y., Pernod, G., Rosencher, N., Roullet, S., Roy, P.M., Samama, C.M., Schlumberger, S., Schved, J.F., Sié, P., Steib, A., Susen, S., van Belle, E., van Der Linden, P., Vincentelli, A., Zufferey, P., Godier, Anne, Fontana, Pierre, Motte, Serge, Steib, Annick, Bonhomme, Fanny, Schlumberger, Sylvie, Lecompte, Thomas, Rosencher, Nadia, Susen, Sophie, Vincentelli, André, Gruel, Yves, Albaladejo, Pierre, and Collet, Jean-Philippe

Published
2018
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43. Choice of factor VIII/IX regimen in adolescents and young adults with severe or moderately severe haemophilia. A French national observational study (ORTHem 15-25)

Author

Borel-Derlon, Annie, Borg, Jeanne-Yvonne, Chambost, Hervé, Claeyssens, Ségolène, d'Oiron, Roseline, Gay, Valérie, Girault, Stéphane, Goudemand, Jenny, Gruel, Yves, Guillet, Benoit, Hassoun, Abel, Meunier, Sandrine, Nguyen, Philippe, Pautard, Brigitte, Peynet, Jocelyne, Rothschild, Chantal, Schved, Jean-François, Trossaert, Marc, Marques-Verdier, Alain, d'oiron, Roseline, Dolimier, Edita, and Guillet, Benoît

Published
2017
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44. Role of factor VIII-binding capacity of endogenous von Willebrand factor in the development of factor VIII inhibitors in patients with severe hemophilia A

Author

Yohann Repessé, Catherine Costa, Roberta Palla, Elika Farrokhi Moshai, Annie Borel-Derlon, Roseline D’Oiron, Chantal Rothschild, Amal El-Beshlawy, Mohsen Elalfy, Vijay Ramanan, Peyman Eshghi, Johannes Oldenburg, Anna Pavlova, Frits R Rosendaal, Flora Peyvandi, Srinivas V. Kaveri, and Sébastien Lacroix-Desmazes

Subjects
Diseases of the blood and blood-forming organs, RC633-647.5
Published
2019
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45. Source Community and Assembly Processes Affect the Efficiency of Microbial Microcystin Degradation on Drinking Water Filtration Membranes

Author

Marisa O. D. Silva, Peter Desmond, Nicolas Derlon, Eberhard Morgenroth, and Jakob Pernthaler

Subjects
biofilm, microcystin, drinking water, membrane filtration, microbial communities, network analysis, Microbiology, QR1-502
Abstract

Microbial biofilms in gravity-driven membrane (GDM) filtration systems can efficiently degrade the cyanotoxin microcystin (MC), but it is unclear if this function depends on the presence of MC-producing cyanobacteria in the source water habitat. We assessed the removal of MC from added Microcystis aeruginosa biomass in GDMs fed with water from a lake with regular blooms of toxic cyanobacteria (ExpL) or from a stream without such background (ExpS). While initial MC removal was exclusively due to abiotic processes, significantly higher biological MC removal was observed in ExpL. By contrast, there was no difference in MC degradation capacity between lake and stream bacteria in separately conducted liquid enrichments on pure MC. Co-occurrence network analysis revealed a pronounced modularity of the biofilm communities, with a clear hierarchic distinction according to feed water origin and treatment type. Genotypes in the network modules associated with ExpS had significantly more links to each other, indicating that these biofilms had assembled from a more coherent source community. In turn, signals for stochastic community assembly were stronger in ExpL biofilms. We propose that the less “tightly knit” ExpL biofilm assemblages allowed for the better establishment of facultatively MC degrading bacteria, and thus for higher overall functional efficiency.

Published
2019
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