21 results on '"D., Sasikala"'
Search Results
2. Necessary or sufficient condition for Alexandroff topological spaces to be cordial graphic
- Author
-
A. Divya, K. Ramya, and D. Sasikala
- Subjects
Alexandroff space ,Vertex labeling ,Graphic topology ,Applied mathematics. Quantitative methods ,T57-57.97 - Abstract
In this paper, we explore the property of being a cordial graphic and establish that it corresponds to an Alexandroff topological space. We analyze how the characteristics of cordial graphs align with the principles of Alexandroff topology and provide insights into their topological structure.
- Published
- 2024
- Full Text
- View/download PDF
3. A contemporary postulates on resolvable sets and functions
- Author
-
M. Deepa, D. Sasikala, and Said Broumi
- Subjects
neutrosophic resolvable sets ,neutrosophic continuous functions ,neutrosophic contra continuous functions ,neutrosophic resolvable functions ,Mathematics ,QA1-939 ,Electronic computers. Computer science ,QA75.5-76.95 - Abstract
In this article, a new class of sets namely neutrosophic resolvable sets in neutrosophic topological space have been introduced. We present the neutrosophic resolvable functions between neutrosophic topological spaces by neutrosophic resolvables sets. Also we examine the characteristics of neutrosophic resolvable sets and neutrosophic resolvable functions with the existing sets.
- Published
- 2023
- Full Text
- View/download PDF
4. A New Perspective of Neutrosophic Hyperconnected Spaces
- Author
-
D. Sasikala and M. Deepa
- Subjects
neutrosophic semi j-open ,neutrosophic semi j-closed ,neutrosophic hyperconnected ,neutrosophic semi j-hyperconnectedness ,Mathematics ,QA1-939 ,Electronic computers. Computer science ,QA75.5-76.95 - Abstract
The focus of this article is to introduce a new class of sets namely neutrosophic semi j-open and neutrosophic semi j-closed sets in neutrosophic topological space. Using this, we present the new spaces neutrosophic hyperconnected and neutrosophic semi j-hyperconnected. Also we explore the characteristics of neutrosophic semi j-open sets, neutrosophic semi j-closed set, neutrosophic hyperconnectedness. Finally we examine the properties of neutrosophic semi j-hyperconnectedness with some existing sets.
- Published
- 2022
- Full Text
- View/download PDF
5. Integrated Dialysis Nursing Intervention for Ameliorating Fatigue in Hemodialysis Patients.
- Author
-
S., Yogalakshmi, D., Sasikala, Varughese, Santosh, and Sundararajan, Vasanthakumari
- Subjects
- *
AEROBIC exercises , *FATIGUE (Physiology) , *HEMODIALYSIS patients , *CHRONIC kidney failure , *SOCIAL skills - Abstract
BACKGROUND: Fatigue is a pervasive and debilitating symptom among hemodialysis patients, severely impacting their quality of life and ability to participate in social activities. Dialysis nurses are pivotal in alleviating these effects through physical exercise. This study aims to evaluate the effectiveness of an integrated dialysis nursing intervention in reducing fatigue among hemodialysis patients. METHODS: A quasi-experimental time series design was employed, involving 295 hemodialysis patients (148 in the experimental group and 147 in the control group) selected through consecutive sampling from two dialysis units in Chennai. Baseline fatigue was assessed in both groups. The experimental group received the integrated dialysis nursing intervention, including 15-minute sessions of aerobic exercises three times a week for eight weeks. The control group continued with routine care. Fatigue levels were reassessed at the end of the fourth and eighth weeks. Data were analyzed using SPSS version 20. RESULTS: The study revealed a significant reduction in fatigue scores in the experimental group compared to the control group, with p < 0.001 in post-test I and II. The experimental group showed greater improvement than the control group, with p < 0.05. Conclusions: The integrated dialysis nursing intervention significantly reduced fatigue in hemodialysis patients. Incorporating this approach into routine intradialytic care can enhance fatigue management and improve patients' quality of life. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
6. A Contemporary Approach on Neutrosophic Nano Topological Spaces
- Author
-
D. Sasikala and K.C. Radhamani
- Subjects
neutrosophic nano j-closed set ,neutrosophic nano generalized closed set ,neutrosophic nano generalized j-closed set ,neutrosophic nano generalized j*-closed set. ,Mathematics ,QA1-939 ,Electronic computers. Computer science ,QA75.5-76.95 - Abstract
In this article, we implement a new notion of sets namely neutrosophic nano j-closed set, neutrosophic nano generalized closed set, neutrosophic nano generalized j-closed set and neutrosophic nano generalized j*-closed set in neutrosophic nano topological spaces. We also provide some appropriate examples to study the properties of these sets. The existing relations between some of these sets in neutrosophic nano topological space have been investigated.
- Published
- 2020
- Full Text
- View/download PDF
7. Service quality of life insurance companies-A comparative study
- Author
-
Devi, D. Sasikala
- Published
- 2016
8. SPECKLE NOISE FILTERING FOR ULTRASOUND IMAGES OF COMMON CAROTID ARTERY: A REVIEW
- Author
-
D. Sasikala and M. Madheswaran
- Subjects
Speckle Noise ,Image Denoising ,Wavelet Thresholding ,Filters ,Telecommunication ,TK5101-6720 ,Computer applications to medicine. Medical informatics ,R858-859.7 - Abstract
Speckle is modeled as a signal dependent noise, which tends to reduce the image resolution and contrast, thereby reducing the diagnostic values of the ultrasound imaging modality. Reduction of speckle noise is one of the most important processes to increase the quality of biomedical images. Filters are used to improve the quality of ultrasound images by removing the noise. This paper compares the performance of the thresholding technique Bayes Shrink in despeckling the medical ultrasound images with other classical speckle reduction filters like Lee, Frost, Median, Kaun, Wavelet Bayes, Anisotropic diffusion and Wavelet. The performance of these filters is analyzed by the statistical measures such as Peak Signal-to Noise Ratio, Mean Square Error and Equivalent Number of Looks. To produce a better quality resolution picture, the filter should have high Peak Signal to Noise Ratio, low Mean Square Error, high Equivalent Number of Looks. The results obtained are presented in the form of filtered images, statistical tables and graphs. Finally, the best filter has been recommended based on the statistical and experimental results. From the results obtained Lee and Frost filter outperforms the other mentioned filters in terms of high PSNR and low MSE for high variance of noise where as anisotropic diffusion filter outperforms with high PSNR and low MSE with maximum ENL for low variance values of noise.
- Published
- 2014
9. Faculty Perception on Simulation Based Learning.
- Author
-
K, Saraswathy, C, Susila, Venkatesan, Latha, K, VIjiyalakshmi, D, Sasikala, and A, Merlin
- Subjects
ONLINE education ,RESEARCH methodology ,NURSING schools ,COLLEGE teacher attitudes ,SATISFACTION ,LEARNING strategies ,PSYCHOSOCIAL factors ,STUDENTS ,COMMUNICATION ,DECISION making ,PROFESSIONAL competence ,NURSING school faculty ,JUDGMENT sampling ,PATIENT safety - Abstract
Introduction: Simulation is an active teaching learning method performed in a controlled, protected and safe environment. The study was aimed to assess the the perception of simulation-based learning among Nursing faculties. Methodology: A descriptive study was conducted at selected college of nursing, Chennai among 63 nursing faculties selected through purposive sampling technique. Data was collected through Google forms using background variables Proforma and rating scale on perception of simulation-based learning through online mode. Results: Around half of the faculties (44.4%) were aged between 36 to 45 years, Post graduates (55.6%) and 49.2% had more than 10 years of teaching experience. Most of them (86%) had positive perception whereas 14% had neutral perception regarding simulation learning, with the domain wise mean score of Clinical skills & Experience (27.1+9.2), communication and patient safety (21.5+7.4), Curriculum Replacement (11.1+2.5), Confidence and Satisfaction of Students (13.5+3.1). Conclusion: Implementation of SBL in Nursing education has been perceived favorably by a large number of Faculties. Faculty development Programme is needed to strengthen the nursing faculties in implementing simulation in a nursing education curriculum. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
10. FLGA Based Best Route Finding for Route Preview Management.
- Author
-
D., Preethi and D., Sasikala
- Subjects
- *
VEHICLE routing problem , *ALGORITHMS , *CUSTOMER services , *LOGISTICS , *COMPUTER programming - Abstract
The system deals with the optimization of vehicle routing problem in which multiple depots, multiple customers, and multiple tollgate are considered. Since the total traveling time is not always restrictive as a time window constraint, the objective in this regard it comprises not only the cost due to the total traveling distance, but also the cost due to the total traveling time. The multidepot vehicle routing problem is one of the common optimization problems in the logistics area. In a real-world environment, drivers choose the shortest route to reach a destination since they assume that it should take the shortest time to travel the shortest route. However, if some events such as traffic congestions, sometime unexpected thing happen in the shortest route, the traveling time spent on this route can be greater than that on the longer route. We propose a stochastic search technique called FLGA to solve the problem. Based on the promising computational results obtained in this proposed system, the proposed model and technique will be effective for industries to be applied in solving real-world problems. It also an unique module to show whether any meeting is on the way chosen by the traveler. If any meeting is found the user can change his route at the place of where the user stays. [ABSTRACT FROM AUTHOR]
- Published
- 2022
11. Structure and dynamics of proflavine association around DNA
- Author
-
Wilbee D. Sasikala and Arnab Mukherjee
- Subjects
Molecular Structure ,010304 chemical physics ,Intercalation (chemistry) ,Stacking ,General Physics and Astronomy ,DNA ,010402 general chemistry ,01 natural sciences ,Small molecule ,0104 chemical sciences ,Kinetics ,chemistry.chemical_compound ,Molecular dynamics ,Crystallography ,Spectrometry, Fluorescence ,chemistry ,0103 physical sciences ,Bound state ,Molecule ,Physical and Theoretical Chemistry ,Dimerization ,Proflavine - Abstract
Proflavine is a small molecule that intercalates into DNA and, thereby, acts as an anticancer agent. Intercalation of proflavine is shown to be a two-step process in which the first step is believed to be the formation of a pre-intercalative outside bound state. Experimental studies so far have been unable to capture the nature of the outside bound state. However, the sub-millisecond timescale observed in fluorescence kinetic experiments is often attributed to the binding of proflavine outside of DNA. Here, we have performed molecular dynamics simulations with multiple proflavine molecules to study the structure and dynamics of the formation of the outside bound state of DNA at different ion concentrations. We observed that the timescale of the outside bound state formation is, at least, five orders of magnitude faster (in nanoseconds) than the experimentally reported timescale (sub-milliseconds) attributed to binding outside DNA. Moreover, we also observed the stacked arrangement of proflavine all around DNA, which is different from the experimentally predicted stacking arrangement perpendicular to the helical axis of DNA in the close vicinity of the phosphate groups. This study, therefore, provides insight into the molecular structure and dynamics of the pre-intercalative outside bound state and will help in understanding the overall intercalation mechanism.
- Published
- 2016
- Full Text
- View/download PDF
12. Molecular Origin of DNA Kinking by Transcription Factors
- Author
-
Arnab Mukherjee, Reman K. Singh, and Wilbee D. Sasikala
- Subjects
HMG-box ,Chemistry ,Intercalation (chemistry) ,DNA ,DNA-binding domain ,Plasma protein binding ,Molecular Dynamics Simulation ,Small molecule ,Surfaces, Coatings and Films ,Molecular dynamics ,chemistry.chemical_compound ,Crystallography ,Materials Chemistry ,Nucleic Acid Conformation ,Thermodynamics ,lipids (amino acids, peptides, and proteins) ,Amino Acids ,Physical and Theoretical Chemistry ,Transcription factor ,Transcription Factors - Abstract
Binding of transcription factor (TF) proteins with DNA may cause severe kinks in the latter. Here, we investigate the molecular origin of the DNA kinks observed in the TF-DNA complexes using small molecule intercalation pathway, crystallographic analysis, and free energy calculations involving four different transcription factor (TF) protein-DNA complexes. We find that although protein binding may bend the DNA, bending alone is not sufficient to kink the DNA. We show that partial, not complete, intercalation is required to form the kink at a particular place in the DNA. It turns out that while amino acid alone can induce the desired kink through partial intercalation, protein provides thermodynamic stabilization of the kinked state in TF-DNA complexes.
- Published
- 2015
- Full Text
- View/download PDF
13. Image registration using modified adaptive polar transform
- Author
-
R. Neelaveni and D. Sasikala
- Subjects
Discrete wavelet transform ,Signal processing ,Lifting scheme ,Computer science ,Stationary wavelet transform ,ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION ,Top-hat transform ,Image registration ,Wavelet ,Pattern recognition ,Computer vision ,S transform ,Continuous wavelet transform ,General Environmental Science ,business.industry ,Second-generation wavelet transform ,Gabor wavelet ,Sequence analysis ,Wavelet transform ,Coding regions ,Time–frequency analysis ,General Earth and Planetary Sciences ,Artificial intelligence ,Harmonic wavelet transform ,Fast wavelet transform ,business - Abstract
Image registration is of great significance to medicine and remote sensing, so a lot of techniques have been developed within the context of one or the other discipline. This paper proposes an approach for medical image registration using Modified Gabor Wavelet Transform (MGWT) for Modified Adaptive Polar Transform (MAPT). This algorithm can be used to register images of the same or different modalities. This transform analyzes periodic signal components and presents the advantage of being independent of the window length. The performance of the Modified Gabor Wavelet Transform is compared with previous methods like Log Polar Transform and Adaptive Polar Transform. The results show that MGWT outperforms all evaluated model-independent methods with respect to identification accuracy. These results show that the basis of errors produced by the previous methods is the fixed working scale. The new method not only avoids this basis of errors but also makes a tool available for detailed study.
- Published
- 2010
- Full Text
- View/download PDF
14. Single water entropy: hydrophobic crossover and application to drug binding
- Author
-
Wilbee D. Sasikala and Arnab Mukherjee
- Subjects
Models, Molecular ,Rotation ,Entropy ,Crossover ,Hydrophobic effect ,Molecular recognition ,Computational chemistry ,Materials Chemistry ,Molecule ,Computer Simulation ,Physical and Theoretical Chemistry ,Total entropy ,Entropy (arrow of time) ,chemistry.chemical_classification ,Hydrogen bond ,Biomolecule ,Proteins ,Water ,Hydrogen Bonding ,Surfaces, Coatings and Films ,Oxygen ,Solutions ,chemistry ,Chemical physics ,Drug Design ,Solvents ,Streptavidin ,Hydrophobic and Hydrophilic Interactions ,Methane - Abstract
Entropy of water plays an important role in both chemical and biological processes e.g. hydrophobic effect, molecular recognition etc. Here we use a new approach to calculate translational and rotational entropy of the individual water molecules around different hydrophobic and charged solutes. We show that for small hydrophobic solutes, the translational and rotational entropies of each water molecule increase as a function of its distance from the solute reaching finally to a constant bulk value. As the size of the solute increases (0.746 nm), the behavior of the translational entropy is opposite; water molecules closest to the solute have higher entropy that reduces with distance from the solute. This indicates that there is a crossover in translational entropy of water molecules around hydrophobic solutes from negative to positive values as the size of the solute is increased. Rotational entropy of water molecules around hydrophobic solutes for all sizes increases with distance from the solute, indicating the absence of crossover in rotational entropy. This makes the crossover in total entropy (translation + rotation) of water molecule happen at much larger size (>1.5 nm) for hydrophobic solutes. Translational entropy of single water molecule scales logarithmically (Str(QH) = C + kB ln V), with the volume V obtained from the ellipsoid of inertia. We further discuss the origin of higher entropy of water around water and show the possibility of recovering the entropy loss of some hypothetical solutes. The results obtained are helpful to understand water entropy behavior around various hydrophobic and charged environments within biomolecules. Finally, we show how our approach can be used to calculate the entropy of the individual water molecules in a protein cavity that may be replaced during ligand binding.
- Published
- 2014
15. Comparative study of flavins binding with human serum albumin: a fluorometric, thermodynamic, and molecular dynamics approach
- Author
-
Abhigyan Sengupta, Wilbee D. Sasikala, Partha Hazra, and Arnab Mukherjee
- Subjects
Flavin Mononucleotide ,Flavoprotein ,Flavin mononucleotide ,Riboflavin ,Flavin group ,Plasma protein binding ,Molecular Dynamics Simulation ,chemistry.chemical_compound ,Flavins ,medicine ,Humans ,heterocyclic compounds ,Fluorometry ,Physical and Theoretical Chemistry ,Serum Albumin ,Flavin adenine dinucleotide ,Binding Sites ,biology ,Circular Dichroism ,Isothermal titration calorimetry ,Human serum albumin ,Atomic and Molecular Physics, and Optics ,Biochemistry ,chemistry ,biology.protein ,Flavin-Adenine Dinucleotide ,Thermodynamics ,medicine.drug ,Protein Binding - Abstract
Flavin adenine dinucleotide (FAD) and flavin mononucleotide (FMN) are derivatives of riboflavin (RF), a water-soluble vitamin, more commonly known as vitamin B(2). Flavins have attracted special attention in the last few years because of the recent discovery of a large number of flavoproteins. In this work, these flavins are used as extrinsic fluorescence markers for probing the microheterogeneous environment of a well-known transport protein, human serum albumin (HSA). Steady-state and time-resolved fluorescence experiments confirm that both FMN and FAD bind to the Sudlow's site-1 (SS1) binding pocket of HSA, where Trp214 resides. In the case of RF, a fraction of RF molecules binds at the SS1, whereas the major fraction of RF molecules remains unbound or surface bound to the protein. Moreover, flavin(s)-HSA interactions are monitored with the help of isothermal titration calorimetry, which provides free energy, enthalpy, and entropy changes of binding along with the binding constants. The molecular picture of binding interaction between flavins and HSA is well explored by docking and molecular dynamics studies.
- Published
- 2012
16. Molecular Origin of DNA Kinking by Transcription Factors.
- Author
-
RemanKumar Singh, Wilbee D. Sasikala, and Arnab Mukherjee
- Published
- 2015
- Full Text
- View/download PDF
17. XML Document Classification by Frequent Itemset Mining on Menonym Tree.
- Author
-
D., Sasikala and K., Premalatha
- Subjects
K-nearest neighbor classification ,FEATURE extraction ,XML (Extensible Markup Language) ,PERFORMANCE evaluation ,BAYESIAN analysis - Abstract
XML has been used as a universal format to design the documents on web, because Mark-up language created using XML for any application does not place any restriction on the number of tags that can be defined. The flexibility to create user-defined tags in XML enables smart searches in large data. The structure of XML provides sophisticated proximity measures as the distance between the last word in one element and the first word in the next element is greater than the distance between adjacent words in the same element, even though their physical proximity in the document is similar. As large number of XML documents are used in the web, classification is needed for efficient data retrieval. This paper is based on document classification for XML semi structured data. In this work, it is proposed to exploit the structure feature of XML data and construct a weighted term frequency feature vector with frequent itemset mining of metonymy tree. Two different classifiers: Naive Bayesian Classifier and K-Nearest Neighbor Classifier are used for classifying the extracted features. Reuter's dataset is used for evaluating the performance of classifiers is compared. [ABSTRACT FROM AUTHOR]
- Published
- 2014
18. Nuclear quadrupole resonance Zeeman spectra of chlorine in 3,4-dichloronitrobenzene. (Crystal structure)
- Author
-
C R K Murty and D Sasikala
- Subjects
Physics ,Electron nuclear double resonance ,Zeeman effect ,General Engineering ,General Physics and Astronomy ,Resonance ,Condensed Matter Physics ,Crystal ,Tetragonal crystal system ,symbols.namesake ,symbols ,Atomic physics ,Nuclear quadrupole resonance ,Single crystal ,Electric field gradient - Abstract
Detailed Zeeman studies of nuclear quadrupole resonance of the 35Cl nucleus in a single crystal of 3,4-dichloronitrobenzene have been made. Two resonance frequencies corresponding to the two positions were observed. The crystal class was identified to be tetragonal. From the Zeeman analysis the field gradient directions, minimum number of molecules per unit cell, asymmetry parameter and hence C-Cl bond characters were determined. The equations for molecular planes were also derived using least squares analysis.
- Published
- 1971
- Full Text
- View/download PDF
19. An efficient Architecture for Barrel Distortion Correction in Surveillance camera images.
- Author
-
A Sathya and D Sasikala
- Published
- 2019
- Full Text
- View/download PDF
20. Crystal structure and bond character study in 3,5-dichlorophenol
- Author
-
C. R. K. Murty and D. Sasikala
- Subjects
Zeeman effect ,Field (physics) ,Chemistry ,media_common.quotation_subject ,General Physics and Astronomy ,Crystal structure ,Asymmetry ,Crystal ,Crystallography ,symbols.namesake ,symbols ,Molecule ,Physical and Theoretical Chemistry ,Nuclear quadrupole resonance ,Single crystal ,media_common - Abstract
Zeeman effect studies of Cl35 nuclear quadrupole resonance have been carried out at room temperature in a single crystal of 3,5‐dichlorophenol. It was confirmed that the crystal belongs to monoclinic symmetry. Two inequivalent field gradient systems were observed. The asymmetry parameter of the field gradient was found to be 0.09± 0.03. The minimum number of molecules in the unit cell and the orientation of the molecular planes with respect to the C axis of the crystal, which is also the growth axis, have been determined. The bond characters of the C–Cl bond have been calculated using the experimental asymmetry parameter.
- Published
- 1973
- Full Text
- View/download PDF
21. Zeeman effect of Cl35 NQR in 2,4-α-α-α- pentachlorotoluene and p-chloroaniline
- Author
-
C. R. K. Murty and D. Sasikala
- Subjects
Zeeman effect ,Pentachlorotoluene ,Field (physics) ,Chemistry ,media_common.quotation_subject ,Analytical chemistry ,General Physics and Astronomy ,Asymmetry ,Crystal ,Crystallography ,symbols.namesake ,symbols ,Physical and Theoretical Chemistry ,Nuclear quadrupole resonance ,Principal axis theorem ,Monoclinic crystal system ,media_common - Abstract
Zeeman effect studies of Cl35 nuclear quadrupole resonance have been carried out at room temperature in single crystals of 2,4‐α‐α‐α‐ pentachlorotoluene and p‐chloroaniline. Two field gradients have been found in the crystal 2,4‐α‐α‐α‐ pentachlorotoluene, one for each chlorine in the 2 and 4 positions. The crystal class is identified as monoclinic. The orientation of the principal axes has been found with respect to the crystallographic axes. The asymmetry parameter cell, and the C–Cl bond characters are estimated. Two inequivalent field gradients have been found in the crystal p‐chloroaniline. The two z axes of the field gradients lie in the ab plane. A comparison of the present results with Meal's data and x‐ray data has been made. It was also found that there is a possibility of different growth habit for the cylindrical crystals in p‐chloroaniline and 2,4‐α‐α‐α‐ pentachlorotoluene.
- Published
- 1973
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.