134 results on '"Džubák, Petr"'
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2. Near-infrared pH-switchable BODIPY photosensitizers for dual biotin/cRGD targeted photodynamic therapy
3. Novel triterpenoid pyrones, phthalimides and phthalates are selectively cytotoxic in CCRF-CEM cancer cells – Synthesis, potency, and mitochondrial mechanism of action
4. Nucleoside-based anticancer drugs: Mechanism of action and drug resistance
5. Molecular design, synthesis and anticancer activity of new thiopyrano[2,3-d]thiazoles based on 5-hydroxy-1,4-naphthoquinone (juglone)
6. Triazole-based estradiol dimers prepared via CuAAC from 17α-ethinyl estradiol with five-atom linkers causing G2/M arrest and tubulin inhibition
7. Lupane derivatives containing various aryl substituents in the position 3 have selective cytostatic effect in leukemic cancer cells including resistant phenotypes
8. Triterpenoid pyrazines and pyridines – Synthesis, cytotoxicity, mechanism of action, preparation of prodrugs
9. Activity of 1-aryl-4-(naphthalimidoalkyl) piperazine derivatives against Leishmania major and Leishmania mexicana
10. Characterization of drug effects on cell cultures from phase-contrast microscopy images
11. Substituted dienes prepared from betulinic acid – Synthesis, cytotoxicity, mechanism of action, and pharmacological parameters
12. Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX
13. Fluorinated derivatives of 2-phenyl-3-hydroxy-4(1H)-quinolinone as tubulin polymerization inhibitors
14. Antimicrobial and cytotoxic activity of (thio)alkyl hexopyranosides, nonionic glycolipid mimetics
15. Novel 5‑Substituted Oxindole Derivatives as Bruton's Tyrosine Kinase Inhibitors: Design, Synthesis, Docking, Molecular Dynamics Simulation, and Biological Evaluation.
16. Synthesis and Biological Evaluation of Oxindole Sulfonamide Derivatives as Bruton's Tyrosine Kinase Inhibitors.
17. Cardiac amyloidosis: from clinical suspicion to morphological diagnosis
18. Two novel mutations (p.(Ser160Pro) and p.(Arg472Cys)) causing glucose-6-phosphate isomerase deficiency are associated with erythroid dysplasia and inappropriately suppressed hepcidin
19. Proteomic profiling reveals DNA damage, nucleolar and ribosomal stress are the main responses to oxaliplatin treatment in cancer cells
20. The natural cytokinin 2OH3MeOBAR induces cell death by a mechanism that is different from that of the “classical” cytokinin ribosides
21. Synthesis, Antimalarial, Antileishmanial, and Cytotoxicity Activities and Preliminary In Silico ADMET Studies of 2-(7-Chloroquinolin-4-ylamino)ethyl Benzoate Derivatives.
22. Synthesis and Biological Profiling of Benzofuro‐Fused 7‐Deazapurine Nucleosides.
23. Improved syntheses of P2X7 ligands based on substituted benzyl amide of pyroglutamic acid motif labelled with iodine-123 or iodine-125.
24. Lupane and 18α-oleanane derivatives substituted in the position 2, their cytotoxicity and influence on cancer cells
25. Reproducibility of Uniform Spheroid Formation in 384-Well Plates: The Effect of Medium Evaporation
26. Synthesis and biological profiling of 6- or 7-(het)aryl-7-deazapurine 4′-C-methylribonucleosides
27. Synthesis of cytotoxic 2,2-difluoroderivatives of dihydrobetulinic acid and allobetulin and study of their impact on cancer cells
28. Synthesis and biological activity evaluation of hydrazone derivatives based on a Tröger’s base skeleton
29. Toll-Like Receptor 7/8 Ligand, S28463, Suppresses Ascaris suum-induced Allergic Asthma in Nonhuman Primates
30. Trilobolide-steroid hybrids: Synthesis, cytotoxic and antimycobacterial activity
31. Proteome Mapping of Cervical Mucus and Its Potential as a Source of Biomarkers in Female Tract Disorders.
32. Síntesis y actividad antiproliferativa de una mezcla de derivados de (+ / -) 7-cloro-(4-tioalquilquinolina). Inducción de apoptosis y daño sobre el ADN/ARN.
33. Cytotoxic heterocyclic triterpenoids derived from betulin and betulinic acid
34. Synthesis of various 5-alkoxymethyluracil analogues and structure–cytotoxic activity relationship study
35. Synthesis of Polycyclic Hetero-Fused 7‑Deazapurine Heterocycles and Nucleosides through C–H Dibenzothiophenation and Negishi Coupling.
36. Novel 7-Chloro-(4-thioalkylquinoline) Derivatives: Synthesis and Antiproliferative Activity through Inducing Apoptosis and DNA/RNA Damage.
37. Synthesis of 5-[alkoxy-(4-nitro-phenyl)-methyl]-uridines and study of their cytotoxic activity
38. Anticancer activity of natural cytokinins: A structure–activity relationship study
39. Cyclocondensation reaction of heterocyclic carbonyl compounds, Part XIII: Synthesis and cytotoxic activity of some 3,7-diaryl-5-(3,4,5-trimethoxyphenyl)pyrazolo[4,3- e][1,2,4]triazines
40. Mixture Effects of Tryptophan Intestinal Microbial Metabolites on Aryl Hydrocarbon Receptor Activity.
41. Synthesis, Leishmanicidal, Trypanocidal, Antiproliferative Assay and Apoptotic Induction of (2-Phenoxypyridin-3-yl)naphthalene-1(2 H)-one Derivatives.
42. Synthesis and anticancer activity of some 1,5-diaryl-3-(3,4,5-trihydroxyphenyl)-1H-pyrazolo[4,3-e][1,2,4]triazines
43. Antiviral Activity of Selected Lamiaceae Essential Oils and Their Monoterpenes Against SARS-Cov-2.
44. Preparation, preliminary screening of new types of steroid conjugates and their activities on steroid receptors
45. New derivatives of silybin and 2,3-dehydrosilybin and their cytotoxic and P-glycoprotein modulatory activity
46. Influence of esterification and modification of A-ring in a group of lupane acids on their cytotoxicity
47. Synthesis of phthalates of betulinic acid and betulin with cytotoxic activity
48. Synthesis and evaluation of the anticancer activity of some semisynthetic derivatives of rutaecarpine and evodiamine.
49. Cytotoxicity of Amino‐BODIPY Modulated via Conjugation with 2‐Phenyl‐3‐Hydroxy‐4(1H)‐Quinolinones.
50. C‐5 Aryl Substituted Azaspirooxindolinones Derivatives: Synthesis and Biological Evaluation as Potential Inhibitors of Tec Family Kinases.
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