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Your search keyword '"Czernichow, S."' showing total 233 results
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233 results on '"Czernichow, S."'

22. Evolution of the nutritional status of COVID-19 critically-ill patients: A prospective observational study from ICU admission to three months after ICU discharge.

Author

Rives-Lange, C., Zimmer, A., Merazka, A., Carette, C., Martins-Bexinga, A., Hauw-Berlemont, C., Guerot, E., Jannot, A.S., Diehl, J.L., Czernichow, S., and Hermann, B.

Abstract

Malnutrition following intensive care unit (ICU) stay is frequent and could be especially prominent in critically ill Coronavirus Disease 2019 (COVID-19) patients as they present prolonged inflammatory state and long length stay. We aimed to determine the prevalence of malnutrition in critically ill COVID-19 patients both at the acute and recovery phases of infection. We conducted a prospective observational study including critically ill COVID-19 patients requiring invasive mechanical ventilation discharged alive from a medical ICU of a university hospital. We collected demographic, anthropometric and ICU stay data (SAPS2, recourse to organ support and daily energy intake). Nutritional status and nutritional support were collected at one month after ICU discharge (M1) by phone interview and at 3 months after ICU discharge (M3) during a specialized and dedicated consultation conducted by a dietitian. Malnutrition diagnosis was based on weight loss and body mass index (BMI) criteria following the Global Leadership Initiative on Malnutrition. Primary outcome was the prevalence of malnutrition at M3 and secondary outcomes were the evolution of nutritional status from ICU admission to M3 and factors associated with malnutrition at M3. From march 13th to may 15th, 2020, 38 patients were discharged alive from the ICU, median [IQR] age 66 [59–72] years, BMI 27.8 [25.5–30.7] kg/m2 and SAPS2 47 [35–55]. Thirty-three (86%) patients were followed up to M3. Prevalence of malnutrition increased during the ICU stay, from 18% at ICU admission to 79% at ICU discharge and then decreased to 71% at M1 and 53% at M3. Severe malnutrition prevailed at ICU discharge with a prevalence of 55% decreasing 32% at M3. At M3, the only factors associated with malnutrition in univariate analysis were the length of invasive mechanical ventilation and length of ICU stay (28 [18–44] vs. 13 [11–24] days, P = 0.011 and 32 [22–48] vs. 17 [11–21] days, P = 0.006, respectively), while no ICU preadmission and admission factors, nor energy and protein intakes distinguished the two groups. Only 35% of undernourished patients at M3 had benefited from a nutritional support. Malnutrition is frequent, protracted and probably underrecognized among critically ill Covid-19 patients requiring invasive mechanical ventilation with more than half patients still being undernourished three months after ICU discharge. A particular attention should be paid to the nutritional status of these patients not only during their ICU stay but also following ICU discharge. [ABSTRACT FROM AUTHOR]

Published
2022
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32. Medications for the treatment of obesity.

Author

Carette, C., Rives-Lange, C., and Czernichow, S.

Subjects
OBESITY, FOOD consumption, DRUGS, DISEASE management, CHRONIC diseases
Abstract

After several years with no real therapeutic alternatives, the management of obesity is entering a new era with the development of new surgical and endoscopic bariatric techniques, digital therapeutics and the arrival of new classes of drugs. New medication treatments aim to reduce food intake, targeting the hypothalamic regulation of food intake and satiety. The mechanism of their action remains poorly understood but, combines weight reduction and amelioration of cardiometabolic risk factors with a favorable benefit-risk balance and known side effects, mainly digestive. The future will tell us how these drugs will find their place in the management of this chronic disease that is obesity. [ABSTRACT FROM AUTHOR]

Published
2023
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37. BMI in relation to sperm count: an updated systematic review and collaborative meta-analysis

Author

Sermondade, N., Faure, C., Fezeu, L., Shayeb, A.G., Bonde, J.P., Jensen, T.K., Van Wely, M., Cao, J., Martini, A.C., Eskandar, M., Chavarro, J.E., Koloszar, S., Twigt, J.M., Ramlau-Hansen, C.H., Borges, E., Jr, Lotti, F., Steegers-Theunissen, R.P.M., Zorn, B., Polotsky, A.J., La Vignera, S., Eskenazi, B., Tremellen, K., Magnusdottir, E.V., Fejes, I., Hercberg, S., Lévy, R., and Czernichow, S.

Published
2013
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38. Contribution of mineral waters to dietary calcium and magnesium intake in a French adult population. (Research)

Author

Galan, P., Arnaud, M. J., Czernichow, S., Delabroise, A.-M., Preziosi, P., Bertrais, S., Franchisseur, C., Maurel, M., Favier, A., and Hercberg, S.

Subjects
Osteoporosis -- Risk factors, Postmenopausal women -- Health aspects -- Food and nutrition, Mineral waters -- Health aspects -- Physiological aspects -- Nutritional aspects, Bones -- Density, Calcium, Dietary -- Physiological aspects -- Health aspects -- Nutritional aspects, French -- Food and nutrition, Food/cooking/nutrition, Nutritional aspects, Physiological aspects, Risk factors, Food and nutrition, Health aspects
Abstract

Objective To assess the contribution of mineral water containing different amounts of calcium and magnesium to the total dietary intakes of these minerals Design Matched case control study using data issued from the Supplementation en Vitamines et Mineraux Antioxydants (SU.VI.MAX) cohort. Subjects Subjects were water consumers--240 men and 424 women--divided into the following 4 groups (n= 166 per group): regular drinkers of a calcium-rich and magnesium-rich mineral water (calcium, 486 mg/L; magnesium, 84 mg/L), drinkers of a water classified as a moderately mineralized content (calcium, 202 mg/L; magnesium, 36 mg/L), drinkers of 2 low-mineralized waters (calcium, 9.9 to 67.6 mg/L and magnesium, 1.6 to 2 mg/L, respectively), and drinkers of tap waters. Statistical analyses Quantitative data were compared using student's t test. Mean comparisons were performed in multivariate analysis by analysis of variance. Results Dietary calcium intake provided by the various food groups did not differ between the 4 consumer groups, except for calcium provided by mineral water. According to its calcium concentration, mineral water may contribute to one fourth of the total daily calcium intake. Subjects who regularly drink mineral-rich water have a calcium intake that is significantly higher (P Applications Mineral-rich water may provide an important supplementary contribution to total calcium and magnesium intake. For dietetics professionals, it may provide--in place of the usual recommendations concerning the consumption of dairy products--a good way to improve calcium and magnesium intakes, particularly in subjects who don't like dairy products. J Am Diet Assoc. 2002;102:1658-1662., Osteoporosis is a bone disease characterized by a reduction in bone tissue relative to the volume of anatomical bone that increases susceptibility to fracture, particularly in menopausal women (1). With [...]

Published
2002

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