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The article presents abstracts of research on sexual medicine. They include "Erection Hardness Is Critical for Good Sex and a Healthy Relationship: The Global Better Sex Survey," "Severe Obstructive Sleep Apnea Syndrome Is Associated With Female Sexual Dysfunction" and "Time Effect on Potency in Post-Radical Cystectomy Patients: Subjective and Objective Evaluation."

Copyright of Andrologie (11662654) is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Andrologie (11662654) is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Résumé Cette revue fait le point sur les mesures médicales d’optimisation du recueil de spermatozoïdes dans les azoospermies non obstructives (ANO). Le traitement substitutif des insuffisances gonadotropes permet d’obtenir des spermatozoïdes dans l’éjaculat dans 90 % des cas s’il est suffisamment prolongé, le recours à la TESE est indiqué en cas de persistance de l’azoospermie à 2 ans de traitement continu. Quelques publications font état d’un possible effet des traitements hormonaux (FSH, hCG, anti-œstrogènes, inhibiteurs de l’aromatase) dans les troubles primitifs de la spermatogenèse, mais essentiellement dans des cas sélectionnés pour leur histologie favorable et leur bilan hormonal normal. L’effet reste incertain pour les cas non sélectionnés. L’optimisation par traitement de varicocèle apparaît significative. Les autres mesures de prise en charge ne reposent pas encore sur des preuves. Medical optimisation of sperm retrieval in non-obstructive azoospermia is reviewed. Gonadotropin treatment of hypogonadotropic hypogonadism allows obtaining sperms in the ejaculate in about 90% of cases provided the duration of treatment was long enough. TESE is indicated in case of persistent azoospermia at 2 years of continuous treatment. Some publications reported a possible effect of hormonal treatments (FSH, hCG, anti-estrogens, aromatase inhibitors) in primary spermatogenic failure, but mainly in cases selected for their favourable histology and normal hormonal levels. The effect on unselected cases remains doubtful. Conversely, the effect of the treatment of varicoceles is significant. Other medical treatments or advises need further investigations. [ABSTRACT FROM AUTHOR]

The article discusses research on the safety and effectiveness of collagenase clostridium histolyticum (CCH) treatment in patients with Peyronie's disease in European Union (EU) patients compared to subjects enrolled in a phase three open-label study in the U.S., New Zealand and Europe. The research assessed improvement in penile curvature deformity and change in Bother domain of Peyronie's disease, as well as treatment emergent adverse events in the patient groups.