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182 results on '"Cruts Marc"'

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1. Prioritization of Drug Targets for Neurodegenerative Diseases by Integrating Genetic and Proteomic Data From Brain and Blood

2. Clinical variability and onset age modifiers in an extended Belgian GRN founder family

4. Frontotemporal dementia and its subtypes: a genome-wide association study

6. Loss of ALS-associated TDP-43 in zebrafish causes muscle degeneration, vascular dysfunction, and reduced motor neuron axon outgrowth

8. Rare nonsynonymous variants in SORT1 are associated with increased risk for frontotemporal dementia

9. Common and rare TBK1 variants in early-onset Alzheimer disease in a European cohort

10. TBK1 Mutation Spectrum in an Extended European Patient Cohort with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis

11. A C9orf72 promoter repeat expansion in a Flanders-Belgian cohort with disorders of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum: a gene identification study

12. Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration

13. TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions

18. Cholesterol and triglycerides moderate the effect of apolipoprotein e on memory functioning in older adults

19. Linkage and association studies identify a novel locus for Alzheimer disease at 7q36 in a Dutch population-based sample

20. Distinct Clinical Characteristics of C9orf72 Expansion Carriers Compared With GRN, MAPT, and Nonmutation Carriers in a Flanders-Belgian FTLD Cohort

21. A Pan-European Study of the C9orf72 Repeat Associated with FTLD: Geographic Prevalence, Genomic Instability, and Intermediate Repeats

25. The gene encoding nicastrin, a major [gamma]-secretase component, modifies risk for familial early-onset Alzheimer disease in a Dutch population-based sample. (Report)

27. Investigating the role of rare heterozygous TREM2 variants in Alzheimer's disease and frontotemporal dementia

29. Genetic and Clinical Features of Progranulin-Associated Frontotemporal Lobar Degeneration

33. Alzheimer and Parkinson Diagnoses in Progranulin Null Mutation Carriers in an Extended Founder Family

34. Progranulin Null Mutations in Both Sporadic and Familial Frontotemporal Dementia

35. Mutations Other Than Null Mutations Producing a Pathogenic Loss of Progranulin in Frontotemporal Dementia

36. Genetic association of apolipoprotein E with age-related macular degeneration

37. A presenilin-1 truncating mutation is present in two cases with autopsy-confirmed early-onset Alzheimer disease

40. Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21

47. High-density SNP haplotyping suggests altered regulation of tau gene expression in progressive supranuclear palsy

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