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Este artigo foi construído na modalidade de relatos de experiências, vivenciadas a partir do Estágio de Clínica da Graduação em Psicologia na Universidade Regional Integrada do Alto Uruguai e das Missões, situada na cidade de Santiago, interior do Rio Grande do Sul. Busca-se por meio deste, cartografar experiências que perpassam a trajetória de formação de um psicoterapeuta, ampliando as possibilidades do fazer clínico e situando a própria figura do terapêuta enquanto um sujeito que afeta e é afetado na medida que a clínica se movimenta nas intervenções que se dão pela relação transferencial e pelas aberturas de uma clínica contemporânea. Para possibilitar a compreensão da experiência, é feito inicialmente um percurso teórico sobre clínica psicanalítica e alguns conceitos fundamentais nesta prática e então, serão apresentados dois casos clínicos no formato de vinheta clínica, possibilitando uma cartografia que irá delinear os trajetos da formação em Psicologia e da prática da Psicoterapia.

Objectives: This study conducts a systematic literature review to explore the role of statistical models and methods in the design of orthopedic implants, with a specific focus on hip arthroplasty. Through a comprehensive analysis of the scientific literature, it aims to understand the relevance and applicability of these models in implant development and research trends in the field of design. Methods: Data analysis and co-occurrence mapping techniques were employed to investigate the statistical models used as predictors of satisfaction in hip arthroplasty and in implant design. This approach facilitated a detailed and objective assessment of existing literature, revealing key trends and identifying gaps in current knowledge. Key findings: The review's findings underscore a burgeoning interest in implant customization, with a significant emphasis on leveraging statistical techniques for optimal design. The logistic model methodology was applied to analyze a survey of hip surgery specialists, revealing that the physician's age does not influence the decision to use a customized implant. Furthermore, the review highlighted a knowledge gap at the intersection of statistics and design discipline concerning implant customization. Significance: Despite the recognized importance of customization in implant design, there remains a dearth of contributions from the design discipline perspective in the existing literature, indicating substantial room for improvement and the need for interdisciplinary integration. Conclusion: The integration of statistical methods in implant design is crucial, emphasizing the need for multidisciplinary approaches and customization to enhance patient satisfaction. This study provides a foundation for future research that could transform the field of hip arthroplasty through more personalized and effective solutions.

Introducción: las almohadillas de grasa peripatelares en la cinemática normal de la rodilla son un elemento fundamental. La rótula alta es uno de los factores etiológicos más importantes de la inestabilidad femororrotuliana y se considera predisponente para el desarrollo del dolor femororrotuliano. El objetivo de este trabajo es demostrar los hallazgos en resonancia magnética del compromiso del sector superolateral externo de la grasa de Hoffa por edema como signo sugestivo de tendón rotuliano largo con rótula alta, y evaluar su sintomatología. Materiales y métodos: se evaluaron retrospectivamente una serie de pacientes y sus resonancias magnéticas de rodilla realizadas en nuestro centro entre 2019 y 2022. Se constató el edema en la región superoexterna de la grasa de Hoffa en los planos sagital, coronal y axial, se efectuaron las medidas de la altura rotuliana mediante el método de Insall-Salvati en la RM en un corte sagital en secuencia T2. Se evaluaron el motivo de consulta y la relación con la imagen observada. Resultados: se evaluaron un total de ciento diecinueve RM, que correspondían a ciento cuatro pacientes. En quince pacientes se analizaron ambas rodillas. Fueron sesenta y cinco de sexo femenino y treinta y nueve, masculino. La edad promedio fue 32.8 años (rango 14-75 años). Se evidenció edema superoexterno de grasa de Hoffa en todas las RM evaluadas, y se observó tendón patelar largo en ciento diecisiete rodillas, lo que representó el 98.3% de la muestra. La altura patelar promedio fue 1.49 según el índice IS (1.12-2.03). En dos RM (1.7%) se vio edema con altura patelar con valores normales de 1.12 y 1.18. Discusión: el edema superoexterno de la grasa de Hoffa tiene una fuerte relación con una altura patelar elevada. Se estudiaron en este trabajo estas variables y se trató de establecer una relación entre ellas. El método de evaluación de patela alta, el índice Insall-Salvati, es el más confiable. Varios estudios correlacionan el edema superoexterno y la patela alta, algunos de ellos asociadas a pacientes jóvenes, mientras que otros lo asocian a signos de artrosis y pacientes más añosos. En cuanto a los síntomas que ocasionan estos hallazgos, son poco claros. Conclusión: en el presente estudio se evidenció que existe una fuerte relación entre el edema superoexterno de la grasa de Hoffa y una patela alta, un signo muy útil a la hora de estudiar y entender la patología femororrotuliana. Observamos una mayor asociación con síntomas patelofemorales y traumatismos de rodilla. A pesar de que esto puede verse en otras patologías.

Common Spatial Pattern (CSP) has been recognized as a standard and powerful method for the identification of Electroencephalography (EEG)-based Motor Imagery (MI) tasks when implementing brain–computer interface (BCI) systems towards the motor rehabilitation of lost movements. The combination of BCI systems with robotic systems, such as upper limb exoskeletons, has proven to be a reliable tool for neuromotor rehabilitation. Therefore, in this study, the effects of temporal and frequency segmentation combined with layer increase for spatial filtering were evaluated, using three variations of the CSP method for the identification of passive movement vs. MI+passive movement. The passive movements were generated using a left upper-limb exoskeleton to assist flexion/extension tasks at two speeds (high—85 rpm and low—30 rpm). Ten healthy subjects were evaluated in two recording sessions using Linear Discriminant Analysis (LDA) as a classifier, and accuracy (ACC) and False Positive Rate (FPR) as metrics. The results allow concluding that the use of temporal, frequency or spatial selective information does not significantly (p< 0.05) improve task identification performance. Furthermore, dynamic temporal segmentation strategies may perform better than static segmentation tasks. The findings of this study are a starting point for the exploration of complex MI tasks and their application to neurorehabilitation, as well as the study of brain effects during exoskeleton-assisted MI tasks.

The Land of Vorarlberg is Austria’s second smallest but most densely populated province after Vienna. Known for its innovative timber architecture, Vorarlberg’s approach integrates ecological, economic, functional, and aesthetic considerations, as championed by Wolfgang Ritsch of the Vorarlberger Architektur Institut (VAI). The region’s timber industry has faced challenges, including local provincialism and modernist material preferences, but gained prominence in the 1990s with the establishment of the Baukünstler group and the Vorarlberger Bauschule, recognised for their contributions to timber construction. Key to this development is Vorarlberg’s significant woodland, covering one-third of its area, and its commitment to sustainable forest management. Regional timber architecture aligns with the principles of appropriate technology, emphasizing eco-responsible, community-driven innovations. Vorarlberg’s timber architecture exemplifies a collaborative effort between designers and craftsmen, focusing on the use of local resources and high construction quality. The essay represents the introduction of notable projects including multifunctional public buildings, schools, offices, and residential complexes, reflecting the region’s commitment to sustainable development and architectural excellence. This ongoing innovation in wood-integrated solutions reinforces Vorarlberg as a hub for eco-friendly and culturally resonant architectural practices.

Starting with theoretical reflections, the issue delves into design experiences across the past, present, and future, illustrating the significant role of timber technology in the Alpine region. In an interview with Hermann Kaufmann, a leading figure in timber construction both locally in Vorarlberg and internationally, we gain insights into the future of timber construction technology from a historical and biographical standpoint. Kaufmann, with his extensive background in the timber construction industry, having been actively involved in workshops and worksites since childhood due to his family’s background in carpentry, provides a valuable perspective on exploring the potential and challenges of timber construction technology. One crucial consideration is the urgent need to decarbonise the built environment in response to the ongoing climate and environmental crisis. Drawing from Kaufmann’s expertise, the discussion also addresses the interplay between timber as a natural material and the increasingly stringent regulations shaping the field of architecture.

This review of selected projects within the Vorarlberg region aims to highlight several architectures, focusing particularly on their construction quality, a distinctive element of the regional architectural production. The projects are grouped by functional theme: starting with an industrial building, specifically a carpentry, moving on to public and private buildings characterized by hybrid spaces capable of hosting a mixed functional program; additionally, there are some school buildings, an office building, and, finally, some residential buildings. The selected projects share the common feature of having a wooden supporting structure, with different construction systems, from frame structures to cross-laminated ones sometimes associated with other technologies such as reinforced concrete.

The selected projects in French and Slovenian territory represent the high degree of experimentation that manifests in these regions in the field of wooden construction. Starting with a redevelopment operation of a public space in Isère, the review moves on to two school buildings that are very different in terms of composition and scale of intervention; additionally, an interesting office building was selected, followed by a residence that explicitly expresses the design and construction potential of cross-laminated timber. The review concludes with a school building in Slovenian territory that features an interesting wooden structure, which determines one of the compositional principles of the entire project.

This review of projects, selected from the provinces of Turin and Cuneo, represents some interesting examples of wooden buildings that often interact with pre-existing structures. In this sense, the use of wooden construction systems demonstrates the remarkable flexibility of this material in relating to existing buildings. Different approaches emerge: in the case of the former Casermette of Moncenisio, there are new buildings inserted within the pre-existing structure, while in the subsequent examples, the new intervention operates through an adjacency to the existing buildings. These projects are part of operations aimed at enhancing local wood, virtuously integrating into regenerative processes of the territory.

The projects featured in this review were selected from the Central and Eastern Italian Alps. Starting with the redevelopment of a rural building in the Aurina Valley, moving on to a trade fair complex in the Belluno area characterized by a significant wooden reticular structure, then the “House of the Mountains” in South Tyrol, and finally a barn designed in the province of Sondrio. The exceptional construction quality of these projects, which are very diverse from one another, indicates a profound knowledge of the material and its design potential.

El afán de presentar con acuciosidad los detalles del tema investigado, obliga en la medida de lo posible a extraer de lo observado, interpretado y reseñado, lo que se considera da explicación y representatividad a las situaciones planteadas, a fin de exponer a juicio del lector los resultados, opiniones y conclusiones al respecto; así el presente ejercicio literario se inicia reflejando someramente la responsabilidad del hombre como principal protagonista del devenir de la humanidad en el planeta, cuya relación produce un dialogo con la naturaleza y todo aquello que es inherente a ella. El agua en el vivir del hombre, no solo como componente fundamental de su condición orgánica, sino como elemento estratégico en la continuidad de su supremacía en el planeta. Siendo el vital líquido el elemento en estudio: presencia y forma de utilización a nivel global y continental, expresado en un acercamiento a la Interacción entre el agua, la sociedad y el medio ambiente. Implicaciones para la subsistencia. Cuya expresión se hace tangible en el entramado que representa dicha relación en el departamento, del Meta y su capital Villavicencio, de la República de Colombia, con vivencias contrastadas en atención a lo que ocurre en otras latitudes de este mundo globalizado, cuyo análisis reafirman los comentarios que dan respuestas a los dos apartes generales del presente estado del arte, complementadas al final por algunas ideas conclusivas que recogen consensos de los aportes de autores presentados, con las cuales se reconocen logros, fortaleciendo el mejor uso del recurso natural.

El objetivo es presentar evidencia empírica sobre el impacto de la migración en salarios y empleo del mercado de trabajo de Colombia, a través de la estimación de un modelo de regresión logística tipo logit multinomial para el empleo y una regresión cuantílica incondicional para el efecto en los salarios, con información de 2015 a 2019. Para ambas estimaciones se emplea un modelo diferencia en diferencias para determinar el efecto de la migración. La principal conclusión del estudio señala evidencia de un efecto sobre la distribución de empleo y salarios que afecta a los grupos más vulnerables, con menor educación e informalidad, a través de un incremento de la competencia en el segmento de mano de obra no calificada. El efecto sobre los salarios es limitado, pero mucho más evidente en los cuartiles de ingresos más bajos de la distribución de ingresos, con una significativa caída en la calidad del empleo con incrementos en la informalidad.

Abstract Parkinson’s disease (PD) and essential tremor (ET) are prevalent movement disorders that mainly affect elderly people, presenting diagnostic challenges due to shared clinical features. While both disorders exhibit distinct speech patterns—hypokinetic dysarthria in PD and hyperkinetic dysarthria in ET—the efficacy of speech assessment for differentiation remains unexplored. Developing technology for automatic discrimination could enable early diagnosis and continuous monitoring. However, the lack of data for investigating speech behavior in these patients has inhibited the development of a framework for diagnostic support. In addition, phonetic variability across languages poses practical challenges in establishing a universal speech assessment system. Therefore, it is necessary to develop models robust to the phonetic variability present in different languages worldwide. We propose a method based on Gaussian mixture models to assess domain adaptation from models trained in German and Spanish to classify PD and ET patients in Czech. We modeled three different speech dimensions: articulation, phonation, and prosody and evaluated the models’ performance in both bi-class and tri-class classification scenarios (with the addition of healthy controls). Our results show that a fusion of the three speech dimensions achieved optimal results in binary classification, with accuracies up to 81.4 and 86.2% for monologue and /pa-ta-ka/ tasks, respectively. In tri-class scenarios, incorporating healthy speech signals resulted in accuracies of 63.3 and 71.6% for monologue and /pa-ta-ka/ tasks, respectively. Our findings suggest that automated speech analysis, combined with machine learning is robust, accurate, and can be adapted to different languages to distinguish between PD and ET patients.

Background Autoimmune encephalitis (AE) consists of a group of acquired diseases that affect the central nervous system. A myriad of phenotypes may be present at the onset. Due to the heterogeneity of clinical presentations, it is difficult to achieve uniformity for the diagnostic and therapeutic processes and follow-up strategies.

The present study evaluates the response to betahistine in patients who presented vestibular drops attacks in the context of Ménière’s disease (MD) and the factors that can predict an unfavorable response to it. A total of 43 patients were analyzed, out of which 33 were diagnosed with MD. This is a descriptive, cross-sectional study with retrospective data collection. Data as regards age, accompanying symptoms, etiological diagnosis and response to MD treatment were collected. A statistical analysis was carried out, and we found that the disease evolution time and specific alterations in the vestibulospinal and oculomotor physical examination present an unfavorable response to betahistine. Failures for betahistine were treated with intratympanic gentamicin, with which symptomatic control was achieved in all cases.

This article aims to present concepts and practices that guide Rural Education in Latin America taking the context of Brazil and Nicaragua as a reference and the defense of a Rural Education with a popular horizon. Results from the dialogic experience of Teacher Training in the perspective of Popular Education in the Countryside between Brazil and Nicaragua. Starting from a hermeneutic approach at first, in addition to reinforcing Latin American views of Rural Education, the study aims to reflect on the identity and belonging of Rural Education that we do. In a second, from the experience of the two countries, to present possibilities of emergence of Pedagogies that emerge from the knowledge of the field. As a result, the potential of progressive popular thought is recognized from the perspective of Paulo Freire, among others, who guide the practices and knowledge of Rural Education. The study demonstrates the effort of the two countries in achieving this purpose.

Background: Diabetic retinopathy (DR) is a leading cause of blindness in patients with type 2 diabetes mellitus (T2DM). Cardiovascular risk factors, such as hypertension, obesity, and dyslipidemia, may play a crucial role in the development and progression of DR, though the evidence remains mixed. This study aimed to assess cardiovascular risk factors as independent predictors of DR and to develop a predictive model for DR progression in T2DM patients. Methods: A retrospective cross-sectional study was conducted on 377 patients with T2DM who underwent a comprehensive eye exam. Clinical data, including blood pressure, lipid profile, BMI, and smoking status, were collected. DR staging was determined through fundus photography and classified as No DR, Non-Proliferative DR (NPDR), and Mild, Moderate, Severe, or Proliferative DR (PDR). A Multivariate Logistic Regression was used to evaluate the association between cardiovascular risk factors and DR presence. Several machine learning models, including Random Forest, XGBoost, and Support Vector Machines, were applied to assess the predictive value of cardiovascular risk factors and identify key predictors. Model performance was evaluated using accuracy, precision, recall, and ROC-AUC. Results: The prevalence of DR in the cohort was 41.6%, with 34.5% having NPDR and 7.1% having PDR. A multivariate analysis identified systolic blood pressure (SBP), LDL cholesterol, and body mass index (BMI) as independent predictors of DR progression (p < 0.05). The Random Forest model showed a moderate predictive ability, with an AUC of 0.62 for distinguishing between the presence and absence of DR XGBoost showing a better performance, featuring a ROC-AUC of 0.68, while SBP, HDL cholesterol, and BMI were consistently identified as the most important predictors across models. After tuning, the XGBoost model showed a notable improvement, with an ROC-AUC of 0.72. Conclusions: Cardiovascular risk factors, particularly BP and BMI, play a significant role in the progression of DR in patients with T2DM. The predictive models, especially XGBoost, showed moderate accuracy in identifying DR stages, suggesting that integrating these risk factors into clinical practice may improve early detection and intervention strategies for DR.

Backround: Depression is a significant concern in clinical and preclinical psychoneurobiological sciences due to its high prevalence and its individual and collective consequences. Identifying efficient biomarkers for accurate diagnosis is crucial, with ideal biomarkers having detectable serum levels and conformational and thermal stability. This study aims to identify stable plasma biomarkers for the diagnosis and prognosis of major depressive disorder, as the pathogenesis of the disorder remains incompletely understood, affecting diagnosis accuracy. Methods: Thus, this study included ten MDD patients and eight healthy controls. The present work analyzed miRNAs in patients with major depressive disorder compared to healthy controls. Results: Eleven specific miRNAs, particularly hsa-miR-874-3p; hsa-let-7d-5p; and hsa-miR-93-3p showed upregulation-type plasma variations in the group of patients with major depressive disorder. miRNA functionality is linked to depressive pathophysiology. Conclusions: This study identifies a “bouquet” of miRNAs with significant upregulation variations in patients with major depressive disorder, suggesting further research to determine their suitability for personalization and evaluation, ultimately becoming integral components of major depression serological evaluations.

Over 60% of reported failures for reactive power compensation systems are given for damage to electrical circuit breaker contacts. This paper presents a study on the development of microwave technology for sintering of W–Cu–Cr alloys at 1012 °C for 65 min using 623.38 W microwave power, as well as microwave joining at 231 °C of the W–Cu–Cr composite material on body contact using 475 W microwave power for 55 s. The joined components were subjected to mechanical and electrical tests in accordance with ICE standards to validate the applied technology. Tests of connection–disconnection of the electrical contacts were carried out in accordance with the maximum number of disconnections allowed by the manufacturer (2 cycles/min): 25 s rest time and 5 s operating time under load. The components of the electrical contact after 111237 switches were analyzed under a microscope revealing a reduction of the damaged area by 27% compared with the original contact.

Las especies híbridas se adaptan mejor a diferentes ambientes que sus progenitores. El pino híbrido (pino híbrido PEE×PCH) entre Pinus elliottii Engelm var. elliottii × Pinus caribaea Morlet var. hondurensis (Sénéclauze) W.H. Barrett & Golfari ha mostrado buen desempeño en regiones subtropicales de Australia, Brasil, Estados Unidos, Sudáfrica y Argentina. Sin embargo, su principal limitante en la expansión del área de plantación es la susceptibilidad del material al daño generado por las bajas temperaturas. Para ello se evaluó por medio de un análisis de componentes principales, como los caracteres asociados a crecimiento, desarrollo fenológico y diferentes condiciones de micrositio afectan a 3 familias de pino híbrido PEE×PCH y a su parental femenino Pinus elliottii. Se encontró un efecto diferencial del daño por bajas temperaturas a nivel sitio de plantación (BAJO y ALTO), especie (PEE y PEE×PCH), pero no a nivel de familia híbrida (F12, F28 y F51) afectando a todas por igual. Su crecimiento inicial y la rápida respuesta a condiciones favorables de crecimiento, son los principales factores que causan la susceptibilidad a bajas temperaturas.

Aquí la autobiografía es el universo por medio del cual pongo en escenario mi vida como medio de catarsis propia y de diálogo con los estudiantes. Aquí trato de desplegar un relato autobiográfico, en el cual describo acontecimientos que han marcado mi vida: el nacimiento, las relaciones con los otros en el colegio, mis temores, los traumas, entre otros. Todo esto para disponerlo en una investigación autoetnográfica donde yo mismo me inscribo como sujeto de investigación. Mi alteridad expresada en narrativa lleva a los niños y niñas partícipes de la investigación, a preguntarse por el otro y sus posibilidades de ser y estar en el mundo. Por ello, la autobiografía es un puente con el cual yo, un otro lleno de posibilidades de ser y estar, recoge la alteridad de sus estudiantes para así, por medio del diálogo con ellos, deconstruir modos de pensar negativos sobre mí.

This essay aims to carry out an analysis of the Psychiatric Counter-Reformation in mental health care processes with the user and the family. It arose as a result of different reflections on daily processes in health services in which the authors take part. The experience in health services and the literature review on the subject produced the results described here, enabling a look at reality with the intention of identifying its most contradictory and multifaceted movements. As a result of these research processes, it was possible to recognize some impacts on mental health care, such as the precariousness of SUS and the return to the asylum logic, the exacerbated responsibility of the family (familism), and the service to users contrary to integrality, in a perspective of slicing the person and his multiple needs. [ABSTRACT FROM AUTHOR]

Background: Patients with chronic pancreatitis can suffer from a range of intense pain, as well as problems related to the functioning of the digestive organs, the evaluation of the quality of life can provide valuable information about the level of physical and emotional discomfort felt by the patients after the surgical intervention. Methods: A prospective study was carried out in the period 2014-2020 in which 113 patients with benign pancreatic pathology treated surgically admitted to the CF2 Clinical Hospital in Bucharest were included. For this study, the statistical method of simple linear regression was applied. Results: Patients' quality of life can also be influenced by the level of social support and medical care they receive. A strong support network, which can provide emotional and practical support, as well as access to appropriate and specialist medical care, can play an important role in managing symptoms and improving patients' quality of life. Conclusions: Although patients in this study experienced significant improvement in symptoms and ability to perform daily activities, it is important to pay attention to and manage persistent symptoms and postoperative complications to ensure the best possible quality of life.

Cushing disease (CD) is the main cause of endogenous Cushing syndrome (CS) and is produced by an adrenocorticotropic hormone (ACTH)-producing pituitary adenoma. Its relevance in pediatrics is due to the retardation of both growth and developmental processes because of hypercortisolism. In childhood, the main features of CS are facial changes, rapid or exaggerated weight gain, hirsutism, virilization, and acne. Endogenous hypercortisolism should be established after exogenous CS has been ruled out based on 24-hour urinary free cortisol, midnight serum or salivary cortisol, and dexamethasone suppression test; after that, ACTH dependence should be established. The diagnosis should be confirmed by pathology. The goal of treatment is to normalize cortisol level and reverse the signs and symptoms. Treatment options include surgery, medication, radiotherapy, or combined therapy. CD represents a challenge for physicians owing to its multiple associated conditions involving growth and pubertal development; thus, it is important to achieve an early diagnosis and treatment in order to control hypercortisolism and improve the prognosis. Its rarity in pediatric patients has led physicians to have limited experience in its management. The objective of this narrative review is to summarize the current knowledge about the pathophysiology, diagnosis, and treatment of CD in the pediatric population.

La enseñanza sistemática y teórica que se ha dado del cálculo en la educación básica y media, responde principalmente al uso y memorización de fórmulas matemáticas totalmente formales, inconexas de la realidad y faltantes de una significativa comprensión, ante esta situación, el presente artículo centra su interés en diseñar un Instrumento manipulativo tangible bajo la perspectiva histórica de Cavalieri, que promueva actividades matemáticas e ideas intuitivas hacia procesos de aprendizaje significativo de la integral respecto al cálculo y comparación de volúmenes a partir de "indivisibles"; caracterizando e interpretando los procesos intuitivos en la enseñanza de la integral, así como las actividades matemáticas emergentes. Desde una metodología cualitativa e interpretativa, se aplicó el recurso sobre un grupo de estudiantes de grado once, mediados por diferentes actividades y preguntas orientadoras a lo largo del estudio, que generaron discusión y evidencias de nociones primarias de: límite, infinito (potencial y actual) e infinitesimal vinculadas a la caracterización epistémica de la integral, al dejarse guiar por la percepción y manipulación, asimismo, se expresaron algunas generalizaciones en cuanto al cálculo de volúmenes. Finalmente, se considera que fomentar el uso no solo del recurso diseñado, sino de cualquier tipo de instrumento cuya construcción y manipulación involucren una reflexión histórico epistémica consciente o inconsciente, genera en los sujetos perspectivas inicialmente intuitivas que potencializan los significados asociados a la integral para el cálculo de volúmenes, dotando igualmente de diferentes sistemas de representación los múltiples conceptos matemáticos puestos en juego para dar respuesta a las preguntas orientadoras durante el desarrollo de la actividad propuesta.

IntroductionThe online misinformation might undermine the vaccination efforts. Therefore, given the fact that no study specifically analyzed online vaccine related content written in Romanian, the main objective of the study was to detect and evaluate tweets related to vaccines and written in Romanian language.Methods1,400 Romanian vaccine related tweets were manually classified in true, neutral and fake information and analyzed based on wordcloud representations, a correlation analysis between the three classes and specific tweet characteristics and the validation of several predictive machine learning algorithms.Results and discussionThe tweets annotated as misinformation showed specific word patterns and were liked and reshared more often as compared to the true and neutral ones. The validation of the machine learning algorithms yielded enhanced results in terms of Area Under the Receiver Operating Characteristic Curve Score (0.744–0.843) when evaluating the Support Vector Classifier. The predictive model estimates in a well calibrated manner the probability that a specific Twitter post is true, neutral or fake. The current study offers important insights regarding vaccine related online content written in an Eastern European language. Future studies must aim at building an online platform for rapid identification of vaccine misinformation and raising awareness for the general population.

Gestational weight gain is an important indicator for monitoring nutritional status during pregnancy. However, there are no gestational weight gain references created for adolescents or national datasets to enable the construction of such graphs up to date. This manuscript aims to describe the creation of a Latin American dataset to construct gestational weight gain references for adolescents aged 10-19 years old. Gestational weight gain data from studies conducted in nine countries (Argentina, Brazil, Chile, Colombia, Mexico, Panama, Paraguay, Peru, and Uruguay) collected between 2003 and 2021 were harmonized. Data on height, weight, and gestational age in at least two gestational trimesters were included. Pregnant adolescents should be free of diseases that could affect weight, and newborns should weigh between 2,500-4,000 g and be free of congenital malformations. The final dataset included 6,414 individuals after data cleaning. Heterogeneity between the countries was assessed by calculating standardized site differences for GWG and z scores of height-for-age. Several imputation procedures were tested, and approximately 10% of the first-trimester weights were imputed. The prevalence of individuals with underweight (1.5%) and obesity (5.3%) was low, which may lead to problems when modeling the curves for such BMI categories. Maternal height and gestational weight gain did not show significant differences by country, according to the standardized site differences. A harmonized dataset of nine countries with imputed data in the first trimester of pregnancy was prepared to construct Latin American gestational weight gain curves for adolescents.

This study does not propose to elucidate how adiponectin secretion is regulated, but how its adiponectin concentration is an indicator of heart disease. About adiponectin, it is not known whether it is functionally an enzyme, or very likely a cytokine/chemokine/hormone, secreted by fat cells/adipocytes in the abdomen. Abdominal fat secretes 67 hormones, and all of which cause disease. For example, adiponectin generates diabetes and ischaemic heart disease via dyslipidemia. Based on clinical symptoms, electrocardiographic and echocardiographic parameters, a group of 208 patients with diastolic cardiac dysfunction with or without preserved systolic function, developed on a background of painful chronic ischaemic heart disease, stable angina on exertion, was constituted. The serum levels of adiponectin, total cholesterol, LDL cholesterol, HDL cholesterol and triglycerides were measured. Using the identified values, it was appreciated whether adiponectin correlates with the type of any of the two conditions, so that it can be recognised as a diagnostic and risk stratification marker.

The first record of well-preserved chondrocranial elements in mosasaurids is here described. These elements are preserved in situ in a Coniacian skull found in north-central Colombia, inside a calcareous concretion. Based on a 3D model generated from computed tomography scans, we identified elements of the nasal and orbitotemporal regions. Our descriptions show that in this specimen, the chondrocranium was reduced, more so than in most lacertilians (including their closest recent relatives, the varanids), but not as severely as in snakes or amphisbaenians (which have an extremely reduced chondrocranium and limbs). The new evidence suggests that the reduction in the chondrocranium in mosasaurids could be related to modification of their limbs when adapting to aquatic environments, but also that in mosasaurids, the olfactory tract was reduced, and the optic muscle insertions occurred mainly in the interorbital septum. The exceptional preservation of the chondrocranial elements in the specimen is facilitated by a gray mineralization covering them. XRD analysis and thin section observations indicated that this mineralization is composed of microcrystalline quartz and calcite. We infer that this material was produced by a partial silicification process promoted by lower pH microenvironments associated with bacterial breakdown of non-biomineralized tissues during early diagenesis.

This article attempts to answer the following question: why did the author of the apocryphon called 1 Apocryphal Apocalypse of John choose to efface himself and adopt John as his pseudonym? Why not Peter or Paul? This paper argues that the author of 1 Apocryphal Apocalypse of John intended to harness the audience attached to John, the seer of Revelation, by taking his name as a pseudonym. This paper sustains this claim by demonstrating that, in antiquity, each author had a specific pool of readers, often made out of friends and accolades of the author. Thus, authors’ names evoke an audience attached to them. When an author takes another person’s name to write under, he does so out of necessity, because he does not have an audience. But, when he takes another’s person name, he does so hoping to trick the audience of the impersonated into reading him. Based on this insight, this article concludes that the author of 1 Apocr. Apoc. John wanted the readers of canonical Revelation to engage with his work and that he achieved his purpose as evinced by the fact that the titles of both works share an uncanny resemblance, ranging from identical titles to similar wording. Since titles in antiquity were given to the works by their readers, the most logical explanation for canonical Revelation and 1 Apocr. Apoc. John having the same titles is that they both shared the same readers. Finally, this article argues that, in line with recent research on the use of pseudepigraphy in Jewish, Christian, and Roman contexts, the author of 1 Apocr. Apoc. John wanted to be read by CR’s readers because he wanted to expand, criticize, rework, and update CR’s eschatological discourse, exemplified by a close reading of how 1 Apocr. Apoc. John criticized, reworked, and updated CR’s presentation of the resurrection to bring it in harmony with late Christian reflection on the subject.

La producción porcina es una de las actividades pecuarias de interés económico de diferentes familias dedicadas a esta actividad pecuaria. La investigación se desarrolló con el objetivo de evaluar la composición nutricional de especies arbustivas tropicales en la alimentación de cerdos de traspatio y se inició con la caracterización proximal de las especies arbustivas presentes en las fincas de los productores de cerdos de traspatio: Morus alba, Erythrina poeppigiana, Hibiscus rosa-sinensis, Trichanthera gigantea, Spondias anacardiaceae, Manihot esculenta, Cnidoscolus aconitifolius, Samanea saman, Gliricidia sepium y Moringa oleífera. Luego, se realizó una prueba de aceptabilidad a las especies con mejor contenido nutricional, a las que cualitativamente se les determinó la presencia de sustancias antinutricionales (alcaloides, fenoles, flavonoides, azucares reductores, mucílago y saponina), visitas según intervalos de tiempo, consumo de las diferentes especies y número de visitas totales. Los datos se analizaron mediante la utilización del programa estadístico Minitab®, versión 18.1, donde los resultados mostraron una mejor composición proximal en las hojas de Cnidoscolus aconitifolius, Morus alba y Moringa oleífera; el tamizaje fitoquímico de las cuatro especies de plantas muestra la ausencia de alcaloides y mucílago en la chaya y la presencia cuantiosa de fenoles en cada especie; la prueba de aceptabilidad mostró que durante los 10 primeros minutos se presentó el mayor número de visitas con un mayor consumo (495,35 g) en el alimento balanceado que incluyó harina de chaya y se concluye que la harina de chaya destaca como la de mejor preferencia alimenticia y el menor contenido de sustancias antinutricionales.

This article recognises the widespread application of risk assessment in ICT and aims at reducing the influence of human subjectivity and distraction by means of a methodology for the Automated and Intelligent Likelihood Assignment (AILA). The AILA Methodology, with its various components, applies when risk assessment proceeds exclusively upon information stated in a policy coming as a text document. This scenario is extremely common through small to medium sized institutions. Among the main contributions of this article lies the AILA Entity Extractor, which facilitates the risk assessor in the identification of entities, then of assets, from a given policy. Then, the AILA Classifier automates the assignment of likelihood values to given threats for assets. Moreover, the synergy of AILA with an existing tool for risk assessment demonstrates how to achieve more objective likelihood assignments. AILA is general in support of any risk assessment and, for the sake of demonstration, is applied to assess the privacy risk induced over physical persons by three real-world manufacturers from the automotive domain, namely Toyota, Mercedes and Tesla. AILA is also validated against a risk assessment methodology by ENISA, thereby confirming effectiveness and efficiency of the new methodology (which is dramatically more automated than ENISA’s). AILA combines and consolidates together several techniques in an unprecedented fashion, including Natural Language Processing by summarisation and entity recognition, dataset labelling by appeal to the ToS;DR service, and fully-supervised Machine Learning and regression analysis. Finally, to contribute to open knowledge, the general, executable components of AILA, the AILA Entity Extractor and the AILA Classifier are released open source along with the privacy-specific components, the AILA Privacy Dataset and the AILA Privacy Model.

Unconformity and distrust are the results of the socio-political attempt aimed to socially and economically evolve under the Top-Down system, finding that “there is no hell like a small town,” a Colombian expression meaning that despite the small size of a social group, its problems could be as big as those of a metropolis. Aipe is one of the Huila’s municipalities that benefited from the oil bonanza, inversely proportional to the social, economic, and environmental bonanza bounty, produced amid a context of political problems of governance and detriment of the public treasury. This article shows results on the relationship between citizen participation and state planning processes in Aipe, which is incoherent, dysfunctional, and inadequate for Aipe’s society, and breeds a citizen climate of distrust and nonconformity towards the authorities and planning instances. Nonetheless, the hope for a prosperous municipality persists because community experiences motivate them to know and empower their territory.

Objetivos: evaluar la adherencia a las recomendaciones de tamización para la prevención de la sepsis neonatal, describir la prevalencia de colonización por estreptococo del grupo B y los desenlaces perinatales asociados a la colonización por esta bacteria. Materiales y métodos: estudio de cohorte retrospectiva que incluyó gestantes a término y sus recién nacidos, en una clínica universitaria privada de alta complejidad en Bogotá, entre el 1 de julio y el 31 de diciembre de 2019. Se evaluó la adherencia a la tamización y a la profilaxis antibiótica intraparto para las gestantes colonizadas con EGB, la prevalencia de colonización y los desenlaces perinatales adversos tempranos. Resultados: se incluyeron 1.928 mujeres. La adherencia a la tamización fue de 68,0 % (IC 95%: 66-70,1), a la administración de antibióticos intraparto de 87,9 % (IC 95 %: 87,8 -88), pero hubo uso no indicado de antibióticos en 14,7 % de mujeres para una adherencia final a profilaxis antibiótica de 86,3 %. La prevalencia de colonización por EGB fue 12,5 % (IC 95 %: 10,7-14,3), la incidencia de hospitalización neonatal fue de 27,5 % (IC 95 %: 16,3-33,7); no hubo casos de mortalidad ni sepsis neonatal temprana atribuibles al estado de tamización, colonización o profilaxis antibiótica para EGB. Conclusiones: se requieren nuevos estudios en otras instituciones para determinar la adherencia a esta guía, en especial en aquellas regiones que atienden usuarias adscritas al régimen subsidiado, con cobertura a la población más vulnerable, así como nuevos estudios poblacionales de prevalencia de EGB y costo-efectividad de la estrategia de tamización universal en comparación con la profilaxis antibiótica basada en factores de riesgo.

Heart transplantation (HTx) represents the current best surgical treatment for patients affected by end-stage heart failure. However, with the improvement of medical and interventional therapies, the population of HTx candidates is increasingly old and at high-risk for mortality and complications. Moreover, the use of “extended donor criteria” to deal with the shortage of donors could increase the risk of worse outcomes after HTx. In this setting, the strategy of donor organ preservation could significantly affect HTx results. The most widely used technique for donor organ preservation is static cold storage in ice. New techniques that are clinically being used for donor heart preservation include static controlled hypothermia and machine perfusion (MP) systems. Controlled hypothermia allows for a monitored cold storage between 4°C and 8°C. This simple technique seems to better preserve the donor heart when compared to ice, probably avoiding tissue injury due to sub-zero °C temperatures. MP platforms are divided in normothermic and hypothermic, and continuously perfuse the donor heart, reducing ischemic time, a well-known independent risk factor for mortality after HTx. Also, normothermic MP permits to evaluate marginal donor grafts, and could represent a safe and effective technique to expand the available donor pool. However, despite the increasing number of donor hearts preserved with these new approaches, whether these techniques could be considered superior to traditional CS still represents a matter of debate. The aim of this review is to summarize and critically assess the available clinical data on donor heart preservation strategies employed for HTx.

Pese a que el Estado chileno viene desarrollando una nutrida ac-tividad en el campo cultural desde los orígenes de la República, la creación en 2003 del Consejo Nacional de la Cultura y las Artes no ha supuesto necesariamente un desarrollo formal de políticas públicas en cultura (pu-blic policies in culture), especialmente porque estas decisiones legislativas, financieras y administrativas que el Estado realiza en el campo cultural no son sujetas a mecanismos conocidos de evaluación ni rendición de cuentas.

Colombia experienced a substantial increase in annual migration flow from Venezuela from 2013 to 2019, accumulating 1.7 million migrants by the end of 2019. According to migration data, 2016 was a breaking point in migration growth, with an increase of 137.57% compared with 2015 and at which time the influx of migrant workers began to be massive, rapid, and involuntary. In this regard, the research paper investigates, using a difference-in-differences model, the impacts on the labor market across different definitions of the informal workforce, testing the hypothesis that short-term labor migration increased (1) the number of employed individuals in companies with a workforce of fewer than five people, (2) the number of employed individuals not contributing to the social security system, and (3) the relative participation of the informal workforce in total employment from 2015 to 2018. The main results indicate an expansion in the labor market’s informal segment, increasing the number of non-returned native workers in the informal workforce without significant increases in the participation of informality in total employment. The results remain robust across various samples in models adjusted for departmental-, municipal-, and individual-level data. Following the economic theory, the research findings seem to follow a transmission mechanism in which migrant workers reduce labor costs and increase production in informal markets, providing better conditions to increase informal jobs for native workers. Several national and international stakeholders implementing income-generation alternatives in the border departments focusing on migrant employment services could find the research findings helpful in at least two aspects: (1) fighting cultural stereotypes upon which basis native workers tend to see migration as a threat to their current job holdings requires evidence that shows migrant workers contribute to economic growth and employment; (2) promoting better public policies to take advantage of initial conditions that favor labor integration of migrant workers such as cultural and language similarities among natives and migrants works better when there is evidence of the migration’s positive impacts.

Background: In human medicine, arrhythmogenic left ventricular cardiomyopathy was described as a primary disease of the heart characterized by fibroadipose replacement of the myocardium. Case Description: We report the case of a dog, with history of syncope and irregular cardiac rhythm. Electrocardiogram, echocardiography and a 24-hours Holter monitoring showed, respectively, presence of premature ventricular complexes with right bundle branch block morphology, increase of the left ventricle end‐diastolic diameter with preserved fractional shortening and ejection fraction, and a sinus arrhythmia as baseline rhythm with supraventricular tachycardia episodes and ventricular complexes with left bundle branch block morphology. After the death of the canine, postmortem examination showed cardiomegaly. Fibroadipose replacement of the septum and both ventricles, with left ventricle myocardial fibrosis, suggestive of a previous necrosis, was observed. Conclusion: These findings are suggestive of a left-dominant arrhythmogenic cardiomyopathy which, to the best of our knowledge, has not been described in veterinary medicine.

El presente ensayo desarrolla un viaje en el tiempo a través de la biografía escolar como un relato de experiencias en las que inicia por la trayectoria formativa desde niño hasta la obtención de la titulación como Licenciado en Educación Física. El ensayo dialoga con las teorías de diversos autores en relación a la temática de la biografía escolar, narrando hechos vividos en los niveles escolares inicial, primario, secundario y universitario, destacando la influencia de los profesores que el autor fue teniendo a lo largo de su vida escolar y académica, concluyendo en que los mismos son influencias fundamentales a lo largo de la vida y que estos son muchas veces relevantes en la formación que tiene un docente a lo largo de su trayectoria académica.

Today, image forgery is common due to the massification of low-cost/high-resolution digital cameras, along with the accessibility of computer programs for image processing. All media is affected by this issue, which makes the public doubt the news. Though image modification is a typical process in entertainment, when images are taken as evidence in a legal process, modification cannot be considered trivial. Digital forensics has the challenge of ensuring the accuracy and integrity of digital images to overcome this issue. This investigation introduces an algorithm to detect the main types of pixel-based alterations such as copy-move forgery, resampling, and splicing in digital images. For the evaluation of the algorithm, CVLAB, CASIA V1, Columbia, and Columbia Uncompressed datasets were used. Of 7100 images evaluated, 3666 were unaltered, 791 had resampling, 2213 had splicing, and 430 had copy-move forgeries. The algorithm detected all proposed forgery pixel methods with an accuracy of 91%. The main novelties of the proposal are the reduced number of features needed for identification and its robustness for the file format and image size.

The aim of this work is to establish the Oxygen Reduction Reaction (ORR) activity of self-standing electrospun carbon fiber catalysts obtained from different metallic salt/lignin solutions. Through a single-step electrospinning technique, freestanding carbon fiber (CF) electrodes embedded with various metal nanoparticles (Co, Fe, Pt, and Pd), with 8–16 wt% loadings, were prepared using organosolv lignin as the initial material. These fibers were formed from a solution of lignin and ethanol, into which the metallic salt precursors were introduced, without additives or the use of toxic reagents. The resulting non-woven cloths were thermostabilized in air and then carbonized at 900 °C. The presence of metals led to varying degrees of porosity development during carbonization, improving the accessibility of the electrolyte to active sites. The obtained Pt and Pd metal-loaded carbon fibers showed high nanoparticle dispersion. The performance of the electrocatalyst for the oxygen reduction reaction was assessed in alkaline and acidic electrolytes and compared to establish which metals were the most suitable for producing carbon fibers with the highest electrocatalytic activity. In accordance with their superior dispersion and balanced pore size distribution, the carbon fibers loaded with 8 wt% palladium showed the best ORR activity, with onset potentials of 0.97 and 0.95 V in alkaline and acid media, respectively. In addition, this electrocatalyst exhibits good stability and selectivity for the four-electron energy pathway while using lower metal loadings compared to commercial catalysts.

Los virus de la leucemia felina (ViLeF) y de la inmunodeficiencia felina (VIF) pertenecen a la familia de retrovirus que afectan a todos los gatos del mundo, incluyendo algunos felinos salvajes. Estos retrovirus comprometen el sistema inmune haciendo susceptibles a los felinos a infecciones secundarias que pueden conllevar enfermedades graves y mortales. A pesar de ser enfermedades de alta importancia clínica, en Colombia el estudio sobre la prevalencia de estas enfermedades en felinos callejeros ha sido escaso. Por lo anterior, se realizó un estudio de prevalencia de leucemia felina y de inmunodeficiencia felina en felinos ferales de la ciudad de Bogotá, en periodos de 1 de junio de 2021 a 20 junio de 2022, y 21 junio de 2022 a abril de 2023. En el primer periodo se incluyeron 397 historias clínicas, con una distribución de género de 37,27 % de hembras y 62,73 % de machos. El segundo periodo contó con 298 historias clínicas, con un 37,91 % de hembras y un 62,09 % de machos. La prevalencia de ambas enfermedades fue más alta en el primer periodo, con un 15,11 % para VIF y un 16,37 % para ViLeF, y en el segundo periodo fue de 13,75 % para VIF y de un 11,40 % para ViLef. Además, el estudio reveló que los machos tenían una mayor probabilidad de infección en ambas enfermedades. Con este estudio se concluyó que estas enfermedades están presentes en una proporción considerable de la población felina feral, condición que debe ser tenida en cuenta para la implementación de medidas preventivas.

El presente trabajo busca analizar las manifestaciones, reproducciones y rupturas discursivas que experimentan las nociones de género a partir de las masculinidades militarizadas presentes en los documentos de defensa del Ecuador. El corpus de análisis está constituido por las políticas de defensa producidas entre 2002 y 2017, considerando el periodo presidencial de Rafael Correa (2007-2017). La Constitución de 2008, con la inclusión de la filosofía indígena del Buen Vivir (Sumak Kawsay), permitió la promoción de políticas públicas direccionadas a alcanzar la equidad de género y la interculturalidad. Las instituciones castrenses se han mostrado especialmente reticentes a los cambios producidos por dichas medidas, generando una militarización de las políticas de género. Es decir, el potencial de cambio que las caracteriza ha sido contenido por la supremacía del ethos militar masculino. El efecto de esa contención —en un país que se autodenomina plurinacional, que reconoce la presencia de diversos pueblos en su territorio— necesita ser analizado, puesto que impacta directamente con las propuestas de inclusión social. Se argumenta que la militarización de elementos como la equidad de género y la interseccionalidad del Buen Vivir, además de corroer el potencial transformador de inclusión social, permite reproducir nuevas formas de manifestación de las masculinidades militarizadas en los documentos de defensa, actualizando las dinámicas que responden a la dicotomía masculino/femenino en un sentido dialéctico y negativo. Para el análisis se emplea una perspectiva de género feminista aliada al análisis del discurso de vertiente francesa, visando examinar las manifestaciones discursivas de las masculinidades militarizadas en los documentos de defensa. A partir del análisis se crearon tres categorías ilustrativas de la presencia de la mujer en los documentos de defensa: ciudadana parcial, ciudadana autorizada, mujer militar. Las tres representaciones muestran, en un antes y un después de las políticas de género, que las mujeres continúan vivenciando rechazo en los espacios militares, ocupando el lugar de un otro. Se concluye que las masculinidades militarizadas han experimentado una metamorfosis discursiva, mostrando el blindaje resistente y sutil del ethos militar masculino. En términos de estructura, el trabajo posee tres secciones. En la primera, se despliegan los instrumentos conceptuales para comprender la relación entre género y masculinidades. Enseguida, se desarrolla una breve descripción de la metodología utilizada. Finalmente, se aplica el dispositivo de análisis a la localización de las manifestaciones de las masculinidades militarizadas en los documentos.

En el presente trabajo se realizó una revisión de las diferentes metodologías matemáticas de cálculo de eficiencia energética en calderas, considerando tanto los métodos incluidos en normas como las diferentes propuestas y aplicaciones publicadas en trabajos investigativos. Se delimitó la clasificación en métodos analíticos, modelados mecanicistas y modelados empíricos. Se exponen las principales ecuaciones para cada una de las metodologías, lo que permite construir una compilación, que se espera que sea de utilidad para una primera aproximación a la temática. Se evidencia que los modelos mecanicistas se emplean para evaluar subsistemas o casos puntuales que requieren alto nivel de detalle, mientras que los modelos analíticos se emplean para realizar una primera aproximación a los sistemas descritos, y los modelos empíricos destacan en cuanto al uso a nivel industrial, siempre y cuando se tenga acceso a una base de datos de partida para ajustarlos.

En el presente artículo se realiza un análisis conceptual y propositivo sobre la ciberdelincuencia que tiene lugar en Colombia, centrándose esencialmente en tres aspectos principales, primero, establecer de forma concreta cual es el alcance de las conductas punibles desplegadas mediante el uso de las tecnologías de la información y las comunicaciones, segundo, desarrollar una aproximación conceptual a la diferencia que debe existir entre los delitos comunes materializados a través de las TIC y los delitos informáticos stricto sensu, y finalmente, analizar la regulación colombiana referente al tema de delitos informáticos propiamente dichos y el bien jurídico que protegen.

En el Ecuador el Código Orgánico de la Economía Social de los Conocimientos contempla la importancia de la participación de estudiantes en el sector socio productivo, considerándose al desarrollo de las habilidades y destrezas del saber hacer como parte de la formación del talento humano. Este artículo tiene por objeto identificar las habilidades técnicas y blandas que influencian la aptitud emprendedora en estudiantes de un Instituto Tecnológico Superior. El tipo de investigación es de enfoque cuantitativo, no experimental, aplicando la técnica de encuesta y el diseño de un cuestionario de 13 preguntas cerradas a 325 estudiantes. Los resultados demostraron que la habilidad técnica predominante en los estudiantes es la planificación y creación de ideas, y la habilidad para la vida de mayor dominio es la creatividad e innovación.