9 results on '"Coelho, Sónia D."'
Search Results
2. Cadmium intake in women from the University of Aveiro, Portugal — A duplicate diet study
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Coelho, Sónia D., Maricoto, Tiago, Pastorinho, M. Ramiro, Itai, Takaaki, Isobe, Tomohiko, Kunisue, Tatsuya, Tanabe, Shinsuke, Sousa, Ana C.A., and Nogueira, António J.A.
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- 2017
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3. House dust fungal communities’ characterization: a double take on the six by sixty by six (6 × 60 × 6) project
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Amaro Raquel, Coelho Sónia D., Pastorinho M. Ramiro, Taborda-Barata Luís, Vaz-Patto Maria A., Monteiro Marisa, Nepomuceno Miguel C.S., Lanzinha Joăo C.G., Teixeira Joăo P., Pereira Cristiana C., and Sousa Ana C.A.
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indoor environmental quality ,fungi ,house dust active sampling ,passive sampling ,Engineering (General). Civil engineering (General) ,TA1-2040 - Abstract
Fungi are a group of microbes that are found with particular incidence in the indoor environment. Their direct toxicity or capability of generating toxic compounds has been associated with a large number of adverse health effects, such as infectious diseases and allergies. Given that in modern society people spend a large part of their time indoors; fungal communities’ characterization of this environmental compartment assumes paramount importance in the comprehension of health effects. House dust is an easy to obtain, time-integrative matrix, being its use in epidemiological studies on human exposure to environmental contaminants highly recommended. Furthermore, dust can carry a great variety of fungal content that undergoes a large number of processes that modulate and further complexify human exposure. Our study aims to identify and quantify the fungal community on house dust samples collected using two different methodologies (an approach not often seen in the literature): active (vacuum cleaner bags) and passive sampling (dust settled in petri dishes). Sampling was performed as part of the ongoing 6 × 60 × 6 Project in which six houses from Covilhă (Portugal), with building dates representative of six decades, were studied for a period of sixty days.
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- 2016
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4. Levels of TBT and other selected organotin compounds in duplicate diet samples.
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Sousa, Ana C.A., Coelho, Sónia D., Pastorinho, M. Ramiro, Taborda-Barata, Luís, Nogueira, António J.A., Isobe, Tomohiko, Kunisue, Tatsuya, Takahashi, Shin, and Tanabe, Shinsuke
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ORGANOTIN compounds , *DIET , *BIOCIDES , *URETHANE foam , *GENETIC toxicology , *IMMUNOTOXICOLOGY - Abstract
Organotin compounds (OTs) are ubiquitous contaminants with a broad range of applications ranging from biocides and pesticides to catalysts for the production of polyurethane foams and silicones. The deleterious effects of some OTs (particularly tributyltin – TBT) upon wildlife and experimental animals are well documented and include endocrine disruption, immunotoxicity, neurotoxicity, genotoxicity and metabolic dysfunction in which obesity is included. However, virtually no data on the current human exposure levels is available. In order to bridge this gap, we quantified for the first time the levels of OTs in duplicate diet samples from members of the University of Aveiro in Portugal. OTs were detected in 32% of the 28 diet samples analyzed, at relatively low levels. TBT and monobutyltin were detected only in two samples and dibutyltin was detectable in three samples. Dioctyltin was quantified in four samples and monooctyltin in three samples. Phenyltins were below the detection limit in all the diet samples analyzed. Overall, for the vast majority of the samples (89%), the estimated daily intakes (EDI) of organotins through food were much lower than the established tolerable daily intakes (TDI). Hence, for the majority of the participants the risk associated with food ingestion is low. [ABSTRACT FROM AUTHOR]
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- 2017
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5. Lead in duplicate diet samples from an academic community.
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Coelho, Sónia D., Pastorinho, M. Ramiro, Itai, Takaaki, Isobe, Tomohiko, Kunisue, Tatsuya, Nogueira, António J.A., Tanabe, Shinsuke, and Sousa, Ana C.A.
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PHYSIOLOGICAL effects of lead , *LEAD in food , *FOOD contamination , *PUBLIC health , *PLUMBING - Abstract
Lead is a naturally occurring element that with the advent of the industrial era became a serious environmental and public health issue. Leaded gasoline, lead based paints, use of lead in plumbing and water pipes, ceramics with lead-containing glazes and tobacco smoke are potential sources of lead exposure for humans. Despite these multiple sources, food is still considered the most important one for the general non-smoking population. Hence, in the present study, the dietary intake of lead was determined in duplicate diet samples provided by 30 participants working or studying at University of Aveiro, Portugal. Pb was detected in all the analysed samples with values ranging between 0.009 and 0.10 mg kg − 1 ww which correspond to estimated daily intakes between 0.22 and 3.5 μg kg-bw − 1 day − 1 . Risk estimations disclose that at least 3.3% and 26.7% of the participants might suffer cardiovascular and nephrotoxic effects, respectively. [ABSTRACT FROM AUTHOR]
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- 2016
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6. Brominated, chlorinated and phosphate organic contaminants in house dust from Portugal.
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Coelho, Sónia D., Sousa, Ana C.A., Isobe, Tomohiko, Kim, Joon-Woo, Kunisue, Tatsuya, Nogueira, António J.A., and Tanabe, Shinsuke
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DUST , *BROMINATION , *FIREPROOFING agents , *CHLORINATION , *PHOSPHATES - Abstract
House dust is an important matrix to evaluate the human exposure to a large number of contaminants including organochlorine compounds and flame retardants. In this study, we measured the levels of polybrominated diphenyl ethers (PBDEs), hexabromocyclododecanes (HBCDDs), 1,2-bis(2,4,6-tribromophenoxy) ethane (BTBPE), decabromodiphenyl ethane (DBDPE), polychlorinated biphenyls (PCBs) and several organophosphorus flames retardants (PFRs) in 28 house dust samples collected between 2010 and 2011 in two Portuguese cities, Aveiro and Coimbra. Among the measured compounds, PFRs, particularly tris(2-ethylhexyl) phosphate (TEHP), triphenyl phosphate (TPHP), 2-ethylhexyl diphenyl phosphate (EHDPP) and tris(methylphenyl) phosphate (TMPP), were the dominant group (median: 3200 ng g − 1 ). PBDE levels were the second highest (median: 340 ng g − 1 ) with great predominance of BDE 209 (median 270 ng g − 1 ), followed by HBCDDs (median: 150 ng g − 1 ), DBDPE (54 ng g − 1 ), PCBs (median: 6.3 ng g − 1 ) and BTBPE (median: 1.2 ng g − 1 ). Estimated daily intakes (EDIs) via dust ingestion showed a higher intake of PFRs (median: 4.6 ng kg-bw − 1 day); however for all contaminants the EDIs were much lower than the established reference dose (RfD) values. Therefore, the studied population is exposed to non-hazardous levels of the target compounds when considering the exposure through house dust ingestion. [ABSTRACT FROM AUTHOR]
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- 2016
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7. Brominated flame retardants and organochlorine compounds in duplicate diet samples from a Portuguese academic community.
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Coelho, Sónia D., Sousa, Ana C.A., Isobe, Tomohiko, Kunisue, Tatsuya, Nogueira, António J.A., and Tanabe, Shinsuke
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BROMINATED hydrocarbons , *FIREPROOFING agents , *ORGANOCHLORINE compounds , *PERSISTENT pollutants , *DIET - Abstract
Concentrations of persistent organic pollutants (POPs), including polybrominated diphenyl ethers (PBDEs), hexabromocyclododecanes (HBCDDs), polychlorinated biphenyls (PCBs), hexachlorocyclohexane isomers (HCHs), hexachlorobenzene (HCB), chlordane compounds (CHLs) and dichlorodiphenyltrichloroethane and its metabolites (DDTs), were measured in duplicate diet samples from 21 volunteers at a Portuguese academic community (University of Aveiro). Overall, the levels of the target compounds were low, with detection frequencies varying widely depending on the compounds and with brominated flame retardants (BFRs) registering the lowest detection frequencies. Among PCB congeners, nondioxin-like PCBs were predominant and detected in the majority of the samples. Organochlorine pesticides were also detected in the majority of the samples, with 100% detection for DDTs and HCHs. Estimated daily intakes (EDIs) were calculated using lower and upper bound estimations, and in both cases values were far below the currently established tolerable daily intakes for PCBs and OCs and the reference doses for PBDEs and HBCDDs. [ABSTRACT FROM AUTHOR]
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- 2016
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8. Responses of benthic macroinvertebrate communities to a Bti-based insecticide in artificial microcosm streams.
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Bordalo, Maria D., Machado, Ana L., Campos, Diana, Coelho, Sónia D., Rodrigues, Andreia C.M., Lopes, Isabel, and Pestana, João L.T.
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INSECTICIDE application ,INVERTEBRATE communities ,BACILLUS thuringiensis ,ALNUS glutinosa ,BIOTIC communities ,PREY availability ,AQUATIC biodiversity - Abstract
Bioinsecticides based on the bacterium Bacillus thuringiensis subsp. israelensis (Bti) are increasingly being applied directly into aquatic compartments to control nuisance mosquitoes and blackflies and are generally considered environmentally friendly alternatives to synthetic insecticides. Bti -based insecticides are considered highly selective, being Diptera-specific, and supposedly decompose rapidly in the environment. Nevertheless, their safety to non-target species and freshwater ecosystems has been questioned by recent studies, which in fact document possible indirect effects in aquatic food webs such as the decrease of prey availability to predators. This work aimed to evaluate the potential effects of a Bti -based insecticide (VectoBac® 12AS) on a freshwater macroinvertebrate community and on stream ecological functions by using artificial microcosm streams. Artificial microcosm streams were colonized with a macroinvertebrate community plus periphyton collected in a stream together with Alnus glutinosa leaf packs. They were exposed for 7 days to different Bti treatments (0, 12, 120, 1200 μg/L), which are within the recommended concentrations of application in aquatic compartments for blackfly and mosquito control. Besides invertebrate community structure and abundance, effects were evaluated regarding leaf decomposition and primary production as measures of ecosystem functioning. Community structure was significantly altered in all Bti treatments after 7 days of exposure, mostly due to a decline in chironomids, followed by oligochaetes, which both belong to the deposit-feeders' functional group. Direct effects on oligochaetes are surprising and require further research. Also, reductions of leaf decomposition due to Bti -induced sublethal effects on shredders (reduced feeding) or mortality of chironomids (that can also feed on coarse organic matter) observed in our study, represent potential indirect effects of Bti in aquatic ecosystems. Our short-exposure experiment evidenced some negative effects on stream benthic invertebrate communities and on ecosystem functioning that must be considered whenever Bti is used in water bodies for blackfly or mosquito control programs. [Display omitted] • Bti effects on community and ecosystem level were evaluated in aquatic mesocosms. • Bti altered macroinvertebrate community, mostly due to effects on chironomids. • Bti impaired ecosystem functioning mainly in terms of leaf decomposition. • Results raise important concerns on the Bti application in aquatic compartments. Seven-day experiment in indoor artificial streams suggests potential negative effects of Bti -based insecticide application in benthic invertebrate communities. [ABSTRACT FROM AUTHOR]
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- 2021
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9. How Does Mytilus galloprovincialis Respond When Exposed to the Gametophyte Phase of the Invasive Red Macroalga Asparagopsis armata Exudate?
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Coelho, Sónia D., Vieira, Hugo C., Oliveira, Jacinta M. M., Pires, Sílvia F. S., Rocha, Rui J. M., Rodrigues, Andreia C. M., Soares, Amadeu M. V. M., Bordalo, Maria D., and Rodríguez, María Pilar Cabezas
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MYTILUS galloprovincialis ,METABOLITES ,CONCENTRATION gradient ,ELECTRON transport ,OXIDANT status ,CARBONYLATION ,PHENOL content of food - Abstract
Asparagopsis armata is classified as an invasive species in Europe. Through the exudation of secondary metabolites, this macroalga holds a chemical defence against consumers, with potential toxic effects to native rocky shore communities. This study aims to evaluate the potential impact of A. armata (gametophyte) exudate in a native species, the mussel Mytilus galloprovincialis, in terms of biochemical and organismal effects. The 96 h-LC50 was 3.667% and based on it, exudate concentrations (0.25; 0.5; 1; 2%) were determined to further sublethal experiments. These sublethal concentrations caused no oxidative damage in the digestive gland since lipid peroxidation and protein carbonylation were not affected. Nevertheless, there was a significant rise in the electron transport system activity and total glutathione content in muscle, suggesting an increased non-enzymatic antioxidant capacity and consequent energy consumption to cope with potential pro-oxidant compounds. This might have contributed to the observed decline in cellular energy allocation of the exposed mussels. At the organismal level, clearance capacity declined along the concentration gradient. Moreover, the number of functional byssuses decreased with increasing concentrations and a significant reduction in their attachment strength was observed. These findings suggest that the presence of A. armata may compromise M. galloprovincialis integrity in the invaded coastal areas. [ABSTRACT FROM AUTHOR]
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- 2021
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