Search

Background: COVID-19 is an unprecedented public health event. It started from Wuhan, China, in late December of 2019 and later spread worldwide. During the pandemic, negative impacts on mental health were found in all groups, including adults of their productive age. Objective: This study aimed to search for factors related to Post Traumatic Stress Symptoms (PTSS) during the quarantine due to the COVID-19 pandemic in Indonesia, specifically about the demographic background of respondents and its relation to PTSS. Methods: This study employed a cross-sectional design involving 257 Indonesian adults aged 26-67 years from 26 out of 34 provinces in Indonesia. The questionnaire used in this study consists of demographic questions and an Indonesian version of the Impact of Event Scale-Revised (IESR). The questionnaire was distributed through a link attached to the social media platform from 17 September to 5 October 2020. Data were analyzed using t-test, one-way ANOVA, and multiple linear regression using SPSS 25.0. Results: The data analysis showed a significant relationship between age and mean IES-R score during quarantine time in Indonesia (p-value 0.001). Other demographic factors such as gender, education level, marital status, work from home, income during the pandemic, and pandemic effects to income showed no significant relation to the IES-R score of the respondents. Adults aged 25-44 years old tend to have higher IES-R scores than those aged 45-64 and 65+ years old. Conclusion: Age was related to the IES-R score, while the other five independent variables included in the linear regression analysis were found to be confounders in this study.

Background: Sinovac was the first vaccine used in Indonesia against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, data regarding the effects of certain variables such as clinical demographics on antibody levels in individuals vaccinated with Sinovac are scarce. This study aimed to investigate the impact of gender and previous SARS-CoV-2 infection status on neutralizing antibody titers 1, 2, and 3 months after administration of the Sinovac vaccine.Method: A cross-sectional study was conducted from February to May 2021. Data on neutralizing antibody levels, previous SARS-CoV-2 infection status, and gender were retrieved from the monthly quantitative serology evaluation database of Siloam Hospitals Lippo Village, Tangerang, Indonesia. The role of each variable was analyzed using the t-test or Mann-Whitney U test, depending on data distribution.Result: Data from 350 participants were collected for the study. Participants with a history of a positive SARS-CoV-2 RT-PCR test had significantly higher neutralizing antibody titers in the first (144 U/mL, p = 0.036) and second months (144 U/mL, p = 0.005) after vaccination compared with those without a history of positive RT-PCR test. Female participants also had significantly higher neutralizing antibody titers in the first, second, and third months (43 U/mL, 42 U/mL, and 39 U/mL, respectively; p = 0.001, p = 0.002, and p = 0.003, respectively) after vaccination compared to males.Conclusion: COVID-19 survivor status and the female gender were associated with higher neutralizing antibody titers after Sinovac vaccine administration.

BackgroundThe preventive measure of Coronavirus Disease pandemic, such as nationwide lockdown, might lead to stress, depression, and anxiety, prominently in adolescents. Many factors were indicated to influence its severity. This study aimed to investigate the magnitude of COVID-19-related mental health problems in adolescents and the associated factors.MethodsThis cross-sectional study gathered 2018 adolescents throughout Indonesia from April 22nd-28th 2020. The questionnaire was spread through social media and included Kessler-10 Psychological Distress scale and closed-ended questions about the risk and protective factors. The results were analyzed using Mann-Whitney U test, Kruskal-Wallis test, and Logistic Regression.ResultsThe participants were mostly males (91.8%) with a median age of 19. The results showed 54.1% experienced varying degrees of distress. All variables were significantly related with psychological distress during Mann-Whitney-U and Kruskal-Wallis test. The logistic regression analysis showed maintaining or improving dietary pattern and sleep quality was found to be protective against psychological distress (OR = 0.497,95%CI = 0.34–0.725 and OR = 0.515,95%CI = 0.372–0.714, respectively), while others were risk factors, i.e.: Not having a confidant (OR = 1.539,95%CI = 1.226–1.931), frequent argument with parents (OR = 1.735,95%CI = 1.343–2.24), feeling worried (OR = 2.364, 95%CI1.528-3.656), chronic diseases (OR = 2.601,95%CI = 1.468–4.606), and mental illnesses (OR = 9.866,95%CI = 3.855–25.249).ConclusionMore than half of adolescents experienced distress. The findings called for initiatives by experts in providing psychosocial support for adolescents.