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B Background: b The presence of microinvasion (MI) such as portal venous, hepatic vein, bile duct infiltration or intrahepatic metastasis, is the best indicator of a poor prognosis after hepatic resection (HR) and transplantation (OLT). The primary end-point of the study is to evaluate the ability of Intraoperative ultrasound (IOUS) to depict the same pathological features (PF) of hepatocellular carcinoma (HCC). B Conclusion: b During the liver resection, IOUS examination can identify aggressive patterns and anatomic hepatic resection or partial hepatic resection with a wide tumor margin should be accomplished to eradicate MI HCC. [Extracted from the article]