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Your search keyword '"CARTER, G. T."' showing total 25 results
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25 results on '"CARTER, G. T."'

5. Making the most of Papua New Guinea’s biodiversity: Establishment of an integrated set of programs that link botanical survey with pharmacological assessment in “the land of the unexpected”.

Author

Barrows, L. R., Matainaho, T. K., Ireland, C. M., Miller, S., Carter, G. T., Bugni, T., Rai, P., Gideon, O., Manoka, B., Piskaut, P., Banka, R., Kiapranis, R., Noro, J. N., Pond, C. D., Andjelic, C. D., Koch, M., Harper, M. K., Powan, E., Pole, A. R., and Jensen, J. B.

Subjects
BIODIVERSITY, DRUGS, DEVELOPING countries, PHARMACOLOGY, TRADITIONAL medicine, SOCIETIES
Abstract

An integrated and coordinated set of programs has been established to meet International Cooperative Biodiversity Group (ICBG) goals in Papua New Guinea (PNG). Here we give an overview of the PNG ICBG and focus on the key elements and major steps taken to establish a program necessary for the pharmacological assessment of botanicals and traditional medicines in PNG and, by extrapolation, in other developing countries. [ABSTRACT FROM AUTHOR]

Published
2009
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8. A4V superoxide dismutase mutation in apparently sporadic ALS resembling neuralgic amyotrophy.

Author

Weiss, M. D., Ravits, J. M., Schuman, N., and Carter, G. T.

Subjects
AMYOTROPHIC lateral sclerosis, MOTOR neuron diseases, SHOULDER pain, SUPEROXIDE dismutase, GENETIC mutation, GENETICS
Abstract

We report a case of apparently sporadic amyotrophic lateral sclerosis (ALS) in a young pregnant woman presenting subacutely with severe left shoulder pain followed by progressive weakness and wasting of the left arm, mimicking neuralgic amyotrophy. She was later found electrophysiologically to have widespread denervation involving more than just the arm and an alanine for valine substitution in codon 4 (A4V) in the gene for Cu/Zn superoxide dismutase 1 (SOD1). Her case illustrates that pain on initial presentation, though uncommon, does not exclude a diagnosis of ALS. [ABSTRACT FROM AUTHOR]

Published
2006
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25. Isolation and identification of antifungal polyesters from the marine fungus Hypoxylon oceanicum LL-15G256

Author

Schlingmann, Gerhard, Milne, Lisa, and Carter, G. T.

Subjects
*MARINE fungi, *METABOLITES, *MACROLIDE antibiotics
Abstract

Cultures of the marine fungus Hypoxylon oceanicum (LL-15G256) were found to have potent antifungal activity in assays designed to detect inhibitors of fungal cell wall biosynthesis. Bio-activity guided isolation provided the macrocyclic polyesters 15G256α (1), 15G256α-1 (2) and 15G256β (3) that were partially responsible for the antifungal activity. In addition, fermentation beers contained a series of related, but unreported metabolites designated 15G256ι (4), 15G256ω (5), 15G256ο (6), 15G256α-2 (7), 15G256β-2 (8), 15G256ν (9) and 15G256π (10). Their isolation, characterization and structures are described here and a biosynthetic sequence is proposed. [Copyright &y& Elsevier]

Published
2002
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