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Epidermoid cysts are most often benign cystic lesions, with uterine cervical localisation being very unusual. We present the case of a 52-year-old female patient diagnosed with an epidermoid cyst at the level of the uterine cervix. A bioptic and haemostatic uterine curettage was performed, followed by total hysterectomy with bilateral adnexectomy. The histopathologic analysis and immunohistochemical essay of the resection specimens confirmed the cervical epidermoid cyst. The presence of high-risk HPV (human papillomavirus) was only seen in the cervical mucosa. The exact etiopathogenesis is unknown, but postpartum cell implantation of reminiscent embryonic tissue can be involved in the development of these lesions. [ABSTRACT FROM AUTHOR]

Simple Summary: In the field of oncology, preclinical research has shown that cannabis and cannabinoids modulate signaling pathways involved in cell proliferation, migration, invasion, angiogenesis, programmed cell death, and metastasis. Based on these findings, as medical cannabis becomes legal in more and more countries, cancer patients and their families are increasingly interested in the potential benefits of herbal medicine as an element of complementary and alternative medicine in their treatment. Although its clinical efficacy has been demonstrated in preclinical studies, clinical trials with cancer patients are lacking. To draw clear conclusions, we await the results of further prospective and randomized studies on this clinically relevant topic. Background and Objectives: Cannabinoids are currently used in cancer patients primarily for their pain-relieving and antiemetic properties. The aim of our review was to synthesize all available data of studies evaluating the therapeutic efficacy of cannabis in combination with oncological treatments in cancer patients and to explore ongoing studies with different goals and medical areas registered in the field of oncology worldwide. Materials and Methods: This study was performed in accordance with the PRISMA guidelines. A search using MEDLINE/PubMed database was performed between 1 January 2006 and 1 March 2022. Search terms included the following: cannabidiol, cannabis, CBD, dronabinol, endocannabinoids, medical marijuana, nabiximols, nabilone, THC, and cancer. All studies that examined the efficacy of cannabis administered during oncological treatments, regardless of cancer localization, subtype, and sample size, were considered eligible. Results: In three studies, cannabis was administered to patients with glioblastoma, and in two other studies, cannabis was used in combination with immunotherapy in various cancer subgroups. The results of the clinical trials in cancer patients are not sufficient to draw conclusions at this time. Interestingly, several other studies addressing the systemic effects of cannabinoids in cancer patients are currently listed in the U.S. National Library of Medicine's registry on the ClinicalTrials.gov website. However, only one of the registered studies examined the efficacy of cannabinoids as a potential option for systemic cancer treatment. Conclusions: Although cannabis is touted to the public as a cancer cure, clinical trials need to clarify which combinations of chemotherapeutic agents with cannabinoids are useful for cancer patients. [ABSTRACT FROM AUTHOR]

Introduction. Understanding the risk factors leading to child abuse is useful when developing effective prevention and early intervention strategies. Modern experts who assessed the environment of the abused child reported that risk factors are multidetermined and are derived from three main etiological causes: parental, ecological and intrinsic problems of the child. Material and methods. A statistical analysis was performed on a group of 176 cases of reported child abuse in Bihor County between 2013 and 2017. The collected data was examined with the use of SPSS 2.0 statistical program. Results. Results demonstrate that the most frequent risk factor involved in physical child abuse is alcohol consumption (28.98% of cases), followed by abuser’s nervousness and drug consumption; the least frequent risk factor being abuser’s response to property theft. Discussions. Physical violence can cause both psychological and physical damage to the child. Research shows that when children experience a certain form of violence, they are also associated with a higher risk of being vulnerable to other forms of abuse. Conclusions. The most frequent risk factor involved in physical abuse of children from Bihor County is alcohol consumption, representing 28.98% of all risk factors analyzed. A holistic approach is absolutely essential for eliminating physical abuse of children. [ABSTRACT FROM AUTHOR]

Death is a universal and inevitable phenomenon, with strong emotional loading for both the dying and those around them (family members or caregivers, of a medical or psychosocial, spiritual nature). The main response to the passing of someone dear is grief, which is usually reversible; however, in some cases, it may generate important general morbidity and mortality risks. Palliative care represents a complex approach meant to improve the quality of life of terminal patients and of their family members, by preventing and mitigating physical pain, as well as psychosocial and spiritual issues. In this field, responsibility toward the patient extends to his/her family after the patient's death. In this paper, the authors analyze the sources of mourning labour, as well as the intervention means suitable for the genuine existential crisis entailed by the passing of a loved one. The importance of the theme resides in the fine line between physiological grief and depression (with all the risks it involves) and in the need of identifying ways to familiarize the family with the idea of death, both before the passing of the dying and afterwards (to facilitate the mourning labour of those left behind and to avoid its complications). [ABSTRACT FROM AUTHOR]