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Abstract The additive Bonvital is a preparation of Enterococcus faecium authorised in feed for piglets and pigs for fattening, sows, chickens for fattening, chickens reared for laying and minor poultry species. The current authorisation in sows does not include the use of the additive in water for drinking. The additive is intended for use in water for drinking for sows at a minimum level of 2.5 × 108 colony forming unit (CFU)/L. This level is half of that minimum authorised in complete feed (5 × 108 CFU/kg), for the same target animals and would provide essentially the same exposure assuming that water consumption is approximately two‐ to three fold greater than feed consumption. Consequently, the conclusions on safety and efficacy of the additive when used in feedingstuffs also apply to its use in water for drinking for sows.

Bonvital is a preparation of a strain of Enterococcus faecium authorised for piglets, pigs for fattening, sows, chickens for fattening, chickens reared for laying and minor poultry species. EFSA was requested to assess the safety and efficacy of Bonvital when used with sows throughout the complete reproductive cycle at the dose of 5 × 108 CFU/kg feed. The safety for the target species, consumers of products derived from animals fed the additive, users and the environment has been considered in the context of the previous opinions. The FEEDAP Panel is not aware of any information that would lead it to revise these conclusions. Consequently, the FEEDAP Panel has considered only the efficacy of Bonvital for sows. The results of three studies each performed over two complete reproductive cycles showed that Bonvital, at the minimum recommended dose of 5 × 108 CFU/kg feed, has the potential to increase litter weight gain or maintain sow condition. Based on these results, the FEEDAP Panel concludes that the data provided support the extension of use of the additive to the entire reproductive cycle.

Bonvital is a preparation of a strain of Enterococcus faecium authorised for use in piglets and pigs for fattening, in sows and in chickens for fattening. The applicant is seeking the further authorisation of Bonvital for use in chickens reared for laying and minor avian species. The E. faecium strain does not contain marker genes typical of hospital-associated isolates responsible for clinical infections and is susceptible to clinically relevant antibiotics. The safety of Bonvital in chickens for fattening has been established in a previous assessment. Since the applicant proposes the use of the same dose (5 x 108 CFU/kg complete feedingstuffs) in chickens reared for laying, safety for this animal category can be presumed. As the same dose is proposed for minor avian species, this conclusion can be extrapolated to minor avian species to point of lay. The strain is not expected to raise concerns for consumers of animal products. Bonvital is not irritant to skin and eyes. In the absence of data, it should be considered to have the potential to be a skin/respiratory sensitiser and treated accordingly. The use of Bonvital under the conditions proposed is considered safe for the environment. The efficacy in chickens for fattening has been established in a previous assessment. Since the applicant proposes the use of the same dose (5 x 108 CFU/kg complete feedingstuffs) in chickens reared for laying, the conclusion on the major species can be extended to this category. As the same dose is proposed for minor avian species and as the mechanism of action of the additive can reasonably be assumed to be the same as in the major species, efficacy in minor avian species to point of lay can be presumed.

Bonvital is a preparation of a strain of Enterococcus faecium authorised for piglets, pigs for fattening, sows, chickens for fattening, chickens reared for laying and minor poultry species. EFSA was requested to assess the safety and efficacy of Bonvital when used with sows throughout the complete reproductive cycle at the dose of 5 × 108 CFU/kg feed. The safety for the target species, consumers of products derived from animals fed the additive, users and the environment has been considered in the context of the previous opinions. The FEEDAP Panel is not aware of any information that would lead it to revise these conclusions. Consequently, the FEEDAP Panel has considered only the efficacy of Bonvital for sows. The results of three studies each performed over two complete reproductive cycles showed that Bonvital, at the minimum recommended dose of 5 × 108 CFU/kg feed, has the potential to increase litter weight gain or maintain sow condition. Based on these results, the FEEDAP Panel concludes that the data provided support the extension of use of the additive to the entire reproductive cycle. [ABSTRACT FROM AUTHOR]

Bonvital is a preparation of a strain of Enterococcus faecium authorised for use in piglets and pigs for fattening, in sows and in chickens for fattening. The applicant is seeking the further authorisation of Bonvital for use in chickens reared for laying and minor avian species. The E. faecium strain does not contain marker genes typical of hospital-associated isolates responsible for clinical infections and is susceptible to clinically relevant antibiotics. The safety of Bonvital in chickens for fattening has been established in a previous assessment. Since the applicant proposes the use of the same dose (5 × 108 CFU/kg complete feedingstuffs) in chickens reared for laying, safety for this animal category can be presumed. As the same dose is proposed for minor avian species, this conclusion can be extrapolated to minor avian species to point of lay. The strain is not expected to raise concerns for consumers of animal products. Bonvital is not irritant to skin and eyes. In the absence of data, it should be considered to have the potential to be a skin/respiratory sensitiser and treated accordingly. The use of Bonvital under the conditions proposed is considered safe for the environment. The efficacy in chickens for fattening has been established in a previous assessment. Since the applicant proposes the use of the same dose (5 × 108 CFU/kg complete feedingstuffs) in chickens reared for laying, the conclusion on the major species can be extended to this category. As the same dose is proposed for minor avian species and as the mechanism of action of the additive can reasonably be assumed to be the same as in the major species, efficacy in minor avian species to point of lay can be presumed. [ABSTRACT FROM AUTHOR]

The additive Bonvital is a preparation of Enterococcus faecium authorised in feed for piglets and pigs for fattening, sows, chickens for fattening, chickens reared for laying and minor poultry species. The current authorisation in sows does not include the use of the additive in water for drinking. The additive is intended for use in water for drinking for sows at a minimum level of 2.5 × 108 colony forming unit (CFU)/L. This level is half of that minimum authorised in complete feed (5 × 108 CFU/kg), for the same target animals and would provide essentially the same exposure assuming that water consumption is approximately two‐ to three fold greater than feed consumption. Consequently, the conclusions on safety and efficacy of the additive when used in feedingstuffs also apply to its use in water for drinking for sows. [ABSTRACT FROM AUTHOR]