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Magneto-electric coupling offers a new pathway to information storage in magnetic memory devices. This phenomenon has been observed in various materials ranging from insulators to semiconductors. In bulk metallic systems, magneto-electric coupling has been disregarded as the electric field cannot enter bulk metals. In this work, we show that a substantial magneto-electric coupling exists in metallic Fe nano-islands grown on Cu(111). Using the electric field in the tunnel junction of a scanning tunneling microscope, the magnetic order parameter and the crystal structure of Fe was changed on the nanometer scale. This allows high density nonvolatile information storage by means of magneto-electric coupling in a simple metallic system.

Objectives The aim of this study was to evaluate whether abdominal myomectomy could be a choice for patients with symptomatic fibroids above the age of 48 years, who wish to get hormonal replacement therapy and desire to retain their uterus. Methods We performed 504 abdominal myomectomies between 1990 and 2004. The mean age was 33 ± 4.09 years, 9 (1.8%; 9/504) patients were above 48 years and 6 (1.19%; 6/504) of them requested hormonal replacement therapy (HRT) after the enucleation of fibroids. Data of these nine cases were compared to a matched control group of patients who had hysterectomy in the same year in 3 months to those who underwent abdominal myomectomy with same indications for surgery, same location, size and number of fibroids. The main aim of our study was to compare perioperative morbidity, duration of hospital stay between myomectomy and hysterectomy groups and determine the recurrence of fibroids and/or symptoms in 1 year with HRT in the myomectomy group. Results The perioperative morbidity did not differ between the compared groups. In the myomectomy group with 1-year HRT we did not observe the recurrence of fibroids and symptoms. Conclusion Our data suggest that abdominal myomectomy may be a satisfactory option for perimenopausal women with symptomatic fibroids who wish to retain their uterus and get HRT.

The quantitative analysis of the reaction products of the water activity dependent nonenzymatic glycosylation of lysozyme was not straightforward. Difficulties arose in the determination of the number of bound glucose molecules because glycosylation leads to glucose mediated protein aggregation, and the likely presence of a mixture of relatively labile Schiff-base intermediates, and the more stable ketoamine products generated by Amadori rearrangement. Polyacrylamide gel electrophoresis was used to monitor protein aggregation; periodate oxidation, nuclear magnetic resonance (NMR), and oxalic acid hydrolysis combined with HPLC, emerged as the most promising methods to quantitate the degree of glycosylation. Possible interpretations are advanced to explain the apparent discrepancies in degree of glycosylation suggested by the different analytical methods evaluated.

Es wird die Oxydation von Phenolen untersucht, die neben anderen Substituenten in einer o-Stellung Isopropyl-,sec.-Butylodertert.-Butylreste tragen2. Die erhaltenen o-Chinolacetate sind von Interesse, weil nach erfolgtem Umsatz aus den erhaltenen verschiedenen Reaktionsprodukten die genannten Reste entfernt werden konnen3.

Zur Synthese substituierter m-Aminophenole sind die durch Bleitetraacetat-oxydation von substituierten Phenolen zuganglichen o-Benzochinol-acetate geeignet1.

Es wird die Synthese einer Anzahl von 1,3-Dioxolan-4-onen und 1,3-Oxathiolan-5-onen beschrieben und uber eine pharmakologische Prufung dieser Substanzen berichtet.

Durch Hydrierung von methylsubstituierten o-Chinondiacetaten gelingt es, reine Brenzcatechinmonoacetate zu erhalten. In mehreren Fallen tritt im Laufe der Hydrierung Umesterung ein; d. h. es liegt der ursprungliche Oxosauerstoff in Form einer Acetatgruppierung vor. Es wird aber auch ein Fall beschrieben, bei dem diese Umesterung nicht eintritt.