51. Withanolides from three species of the genus Deprea (Solanaceae). Chemotaxonomical considerations.
- Author
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Casero, Carina N., Oberti, Juan C., Orozco, Clara I., Cárdenas, Alejandro, Brito, Iván, Barboza, Gloria E., and Nicotra, Viviana E.
- Subjects
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WITHANOLIDES , *PLANT chemotaxonomy , *SOLANACEAE , *PHYSALINS , *NUCLEAR magnetic resonance spectroscopy , *X-ray diffraction , *BOTANICAL chemistry - Abstract
Nine withanolides were isolated from the aerial parts of Deprea bitteriana , D eprea cuyacensis , and D eprea zamorae . D . bitteriana yielded two withaphysalins, D. cuyacensis gave two 13,14-seco withaphysalins, while D. zamorae yielded five physangulidines. The compounds were fully characterized by a combination of spectroscopic methods (1D and 2D NMR and MS). All compounds isolated from D . bitteriana and D. cuyacensis were obtained as epimeric mixtures at C-18. The structure of physangulidine D was confirmed by X-ray diffraction analysis. The skeletons found in this research support the chemotaxonomical position of the genus Deprea in the tribe Physalideae. [ABSTRACT FROM AUTHOR]
- Published
- 2015
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