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This article examines the transformation of television serial fiction in Spain from deregulation and the early stages of private television to the dawn of the digital era (1990–2010). The adaptation of Latin-American telenovelas and English-speaking soap operas to the local context brought traditional Spanish costumbrismo in television fiction up to date. Using this as a starting point, the study identifies four stages of the long-running serial format in Spain that demonstrate its capacity to adapt to a double logic of transnationalization maintaining proximity to regional markets alongside a process of gradual adjustment to the changing social, cultural and economic context. The consolidation of democracy in Spain and successive Socialist administrations (1982–1990) favoured the renewal of themes from classical melodrama with the inclusion of issues until then barely addressed, including women's liberation, sexuality and the recovery of historical memory: topics that have become the mainstay of Spanish television serial fiction in the twenty-first century. [ABSTRACT FROM AUTHOR]

The aim of this paper is to show the limited inclusion of journalists of migrant origin in Spanish mainstream media, analyzing not only their difficulties in getting a job in the media industry and the precarious working conditions here prevail, but also the struggle of these journalists to acquire visibility and recognition as media professionals. These journalists" inclusion must be framed in a highly unfavourable context, characterized by chronic deregulation. The analysis of migrant journalists" job inclusion surpasses work conditions to highlight the debate about the possibilities of development of a public sphere that really reflects the multicultural society in which we live. Thus, the basic argument that lies behind the analysis is the democratization of national media field. [ABSTRACT FROM AUTHOR]

After advocating flexibilisation of non-standard work contracts for many years, some European and international institutions and several policy makers now indicate the standard employment relationship and its regulation as a cause of segmentation between the labour market of ‘protected’ insiders, employed under permanent contracts with effective protection against unfair dismissal, and the market of the ‘non-protected’ outsiders, working with non-standard contracts. Reforms of employment legislation are therefore being promoted and approved in different countries, supposedly aiming to balance the legal protection afforded to standard and non-standard workers. This article firstly argues that this approach is flawed as it oversimplifies reasons for segmentation and concentrates on an ‘insider–outsider’ discourse that cannot easily be transplanted into continental Europe. After reviewing current legislative changes in Italy, Spain and Portugal, I argue that lawmakers have focused on ‘deregulation’ rather than ‘balancing protection’ when approving recent reforms. I question the mainstream approach to segmentation and some of its derivative proposals, such as calls to introduce a ‘single permanent contract’, on the grounds that they neglect the essential role of job protection in underpinning the effectiveness of fundamental and constitutional rights at the workplace. [ABSTRACT FROM AUTHOR]

The ongoing financial crisis has exacerbated concerns about the need to redefine the role and characteristics of regulation. In the case of public services, deregulation was justified by the benefits that would accrue to consumers, though scant attention was paid to actual consumer experience in regulatory design. New European public services regulation policies argue that the citizens' perspective should be considered, with the aim of improving the functioning of the markets whilst protecting the general interest. The decisions and attitudes of Spanish citizens regarding two public services, electricity and telecommunications, are analysed. The novelty of this article is to contrast revealed and declared preferences, a method which has not yet been used in analysing public service use. The results show when and how socio-economic variables affect service use and satisfaction and the conclusions indicate how the results could be used to formulate better policies to address issues of social inclusiveness. [ABSTRACT FROM AUTHOR]

This paper analyzes the case of Spain in the period from 1993 to 2005, when intense reforms in several industries took place in the country. We observe an increase in collusion and trust practices in liberalized industries, what requires an increase in the resources dedicated to antitrust policy. An econometric estimation demonstrates the influence that certain regulatory dimensions have on antitrust activity. Deregulation has an additional positive effect on antitrust activity. We also observe a learning effect in industries due to previous sanctions. Finally, we find a complementarity effect of regulatory agencies on the antitrust policy. [ABSTRACT FROM AUTHOR]

Journalistic self-regulation recommends respect to the weak and disadvantaged people. In our quantitative analysis, journalists show themselves sensitive to disadvantaged groups. However, they disagree about the most appropriate treatment. The results of in-depth interviews reflect the same lack of consensus among journalists about the role the media should take to disadvantaged groups: a) giving visibility to certain disadvantaged; b) Certain economic benefits campaigns; c) Media are businesses. The disadvantaged are not their cause. Citizens see no objection to explicit certain attributes of the protagonists of the news, especially those related to age or gender. According to the results of the bivariate analysis, women and those who are more critical to journalistic ethics are less in favour to explicit certain attributes related to sexual orientation, ethnicity or nationality. In all other cases there are no significant differences. In focus groups, citizens perceive that, in general, minorities are distorted in the news. For all participants, disadvantaged groups, only have significance in the media on negative events. Youth and adults from Madrid consider that the media exploit the events associated with these groups to feed the curiosity and increase the audience. The more educated adults claim that the use of euphemisms can not change stereotypes. [ABSTRACT FROM AUTHOR]

Simple Summary: Hepsin is a serine protease whose deregulation leads to tumor invasion and metastasis in many tumor types. In colorectal cancer, the role of hepsin is unknown, so we aimed to study the correlations between its expression and clinical-histopathological variables of patients with this cancer. We recruited 169 patients with localized disease and 118 with metastatic cancer at diagnosis, and then, we measured hepsin staining from primary biopsy in order to correlate it with time-to-event variables, laboratory data, genetic alterations, histologic features, etc. Our results demonstrated hepsin was an independent prognosis factor for metastasis and thrombosis in patients with localized disease, whereas among metastatic subjects, lower levels of hepsin were associated with highest tumor dedifferentiation and spread to distant organs. These results point to hepsin as a potential biomarker for considerable complications in patients with colorectal cancer. In addition, this article brings to light new information about the implication of hepsin in colorectal cancer. Hepsin is a type II transmembrane serine protease whose deregulation promotes tumor invasion by proteolysis of the pericellular components. In colorectal cancer, the implication of hepsin is unknown. Consequently, we aimed to study the correlations between hepsin expression and different clinical-histopathological variables in 169 patients with localized colorectal cancer and 118 with metastases. Tissue microarrays were produced from samples at diagnosis of primary tumors and stained with an anti-hepsin antibody. Hepsin expression was correlated with clinical-histopathological variables by using the chi-square and Kruskal–Wallis tests, Kaplan–Meier and Aalen–Johansen estimators, and Cox and Fine and Gray multivariate models. In localized cancer patients, high-intensity hepsin staining was associated with reduced 5-year disease-free survival (p-value = 0.16). Medium and high intensity of hepsin expression versus low expression was associated with an increased risk of metastatic relapse (hazard ratio 2.83, p-value = 0.035 and hazard ratio 3.30, p-value = 0.012, respectively), being a better prognostic factor than classic histological variables. Additionally, in patients with localized tumor, 5-year thrombosis cumulative incidence increased with the increment of hepsin expression (p-value = 0.038). Medium and high intensities of hepsin with respect to low intensity were associated with an increase in thrombotic risk (hazard ratio 7.71, p-value = 0.043 and hazard ratio 9.02, p-value = 0.028, respectively). This relationship was independent of previous tumor relapse (p-value = 0.036). Among metastatic patients, low hepsin expression was associated with a low degree of tumor differentiation (p-value < 0.001) and with major metastatic dissemination (p-value = 0.023). Hepsin is a potential thrombotic and metastatic biomarker in patients with localized colorectal cancer. In metastatic patients, hepsin behaves in a paradoxical way with respect to differentiation and invasion processes. [ABSTRACT FROM AUTHOR]

Primary immune thrombocytopenia (ITP) is a complex autoimmune disease whose hallmark is a deregulation of cellular and humoral immunity leading to increased destruction and reduced production of platelets. The heterogeneity of presentation and clinical course hampers personalized approaches for diagnosis and management. In 2021, the Spanish ITP Group (GEPTI) of the Spanish Society of Hematology and Hemotherapy (SEHH) updated a consensus document that had been launched in 2011. The updated guidelines have been the reference for the diagnosis and management of primary ITP in Spain ever since. Nevertheless, the emergence of new tools and strategies makes it advisable to review them again. For this reason, we have updated the main recommendations appropriately. Our aim is to provide a practical tool to facilitate the integral management of all aspects of primary ITP management. [ABSTRACT FROM AUTHOR]

This paper examines the evolution of the Spanish gasoline market from the abolition of the state oil monopoly (January 1993) to "complete" liberalisation (October 1998). With the restructuring of the Spanish oil sector during the 1980s and early 1990s, a highly concentrated oligopoly emerged in the automotive fuels market. A system of price ceilings replaced the state administered prices in July 1990. Since then, new domestic and foreign operators have entered the market, particularly along the coast, near import terminals. Prices went up and then declined. These developments can be explained by an interplay of factors such as: the gradual decline in co-operation among the Spanish firms; the loss of market share of the largest of these, Repsol; the entry of independent operators and supermarkets; and the impact of the ceiling price system. By mid-1998 this system was abolished as the government considered it an "impediment" to further market liberalisation. However, some crucial barriers to the entry of new suppliers remain. [ABSTRACT FROM AUTHOR]

The place of labor in market reform coalitions, ranging from democratic inclusion to labor repression, triggers a trade-off between the degree of deregulation in the formal sector and the amount of compensations targeted to the unemployed and poor workers in the informal sector. Comparative analysis of Chile (1973-1989), Argentina (1989-99), and Spain (1982-96) reveals that, the more organized labor is included in the policymaking process, the less extensive reform of the system of industrial relations will be. Conversely, the more organized labor is repressed or excluded, the more labor law will be deregulated. In addition, when labor is excluded or repressed, the relative importance of compensatory policies in the form of subsidies to unemployed and unorganized workers in the informal sector is greater. [ABSTRACT FROM AUTHOR]

The expansion of the platform economy has altered the spatial organization of work and employment relations, leading to deregulation and eroding workers' social power. However, despite the radical individualization and precarization of platform work, workers demonstrate agency. This article explores the political strategies employed by place-based platform workers, with a particular focus on the spatiality of their collective action. Using an ethnographic methodology, the article analyses the case studies of drivers' trade associations in Chile and the couriers' organization in Spain. The results show significant similarities between the two groups: (a) non-conventional forms of labour activism; (b) using social media to share experiences, foster solidarity and organize collectively; (c) organizing in large cities; (d) starting locally and progressing to higher scales, and (e) building national and international alliances. The article concludes that workers respond to the spatial organization of work by platforms in a multi-scalar way that is strongly influenced by both their imaginaries and the political and regulatory context. [ABSTRACT FROM AUTHOR]

Conventional wisdom has it that the food economy has transitioned from organized to disorganized capitalism. An era of extensive state intervention between around 1930 and 1980 would have been followed by an era of deregulation and increasing coordination through markets after around 1980. This article uses the case of Spain's dairy chain to propose an alternative view. In the case under study, there certainly were elements of state‐coordinated capitalism between 1952 and 1986, as well as elements of deregulation and liberalization from 1986 onwards. However, the structure of economic coordination involved some combination of market and nonmarket mechanisms all the way through. The organized capitalism of the first period was not really so tightly organized, whereas much of its later "disorganization" was in fact a transition towards a different mode of "organization": one in which the control of nonmarket coordination shifted from political to corporate hierarchies. [ABSTRACT FROM AUTHOR]

The integration of the residential function beyond the limits of the urban and developable land in the legislative frameworks has had a distinct and incomplete character. Faced with an identical phenomenon in general, called urban sprawl, the competent governments in this matter within the Iberian Peninsula have opted for a dissimilar assimilation of it, materialized in different legal and instrumental mechanisms. The objective of this paper is to present the different ways of understanding and regulating this new urban model by the Portuguese state government and the regional autonomous governments in Spain. To do this, a comparative analysis is carried out on the criteria for the classification of undeveloped land and a review of the most paradigmatic tools for the management of periurban and rurban development. The works indicate a position that is still indeterminate and, sometimes, contradictory. In spite of this, there is a tendency towards the regulated inclusion of the residential function outside the geographical contexts that have traditionally supported it. [ABSTRACT FROM AUTHOR]

Abstract: We examine variations in financial and economic performance as a function of organizational form, and, over time. The forms we consider include Spanish commercial banks, savings banks, and financial cooperatives. We decompose multilateral variation in operating profit, our measure of financial performance, into price and quantity effects. We then decompose the latter into a margin effect and productivity change. Our measure of economic performance, productivity variation, is subsequently disaggregated into technical, cost efficiency, and scale. We find that deregulation and liberalization have acted to narrow performance gaps among organizational forms; this, despite less-than compelling evidence that increased competition has contributed to this convergence. For the Spanish banking system as a whole, the margin effect appears to deliver twice as much financial benefit as do improvements in productivity. Importantly, this finding does not vary across organizational form. Such regularity has an important implication: Incentives for growth are apparently provided by a positive margin rather than by the more elusive benefits of economies of scale and improved cost efficiency. [Copyright &y& Elsevier]

Abstract: In new deregulated electricity market, price forecasts have become a fundamental input to an energy company’s decision making and strategy development process. However, the exclusive characteristics of electricity price such as non-stationarity, non-linearity and time-varying volatile structure present a number of challenges for this task. In spite of all performed research on this area in the recent years, there is still essential need for more accurate and robust price forecast methods. Besides, there is a lack of efficient feature selection technique for designing the input vector of electricity price forecast. In this paper, a new two-stage feature selection algorithm composed of modified relief and mutual information (MI) techniques is proposed for this purpose. Moreover, cascaded neural network (CNN) is presented as forecast engine for electricity price prediction. The CNN is composed of cascaded forecasters where each forecaster is a neural network (NN). The proposed feature selection algorithm selects the best set of candidate inputs which is used by the CNN. The proposed method is examined on PJM, Spanish and Ontario electricity markets and compared with some of the most recent price forecast techniques. [Copyright &y& Elsevier]

The paper focus on a critical analysis of a discursive formation in Spanish academic libraries: social responsibility and sustainability. The concepts that make up the discourse are historically contextualized in order to clarify their origin and social affiliation. Although the enunciation of social responsibility and sustainability content is formulated ambiguously, its articulation as a discursive practice within the framework of the new corporate management university libraries leads us to infer bias in their rhetorical formulation. We consider that, from a fuzzy concept and its integration into technocratic practices, the discourse can be used as a tool for legitimizing the deregulation of public educational institutions. [ABSTRACT FROM AUTHOR]

The concept of financialisation is being widely used to describe certain structural changes in advanced capitalist economies. The main approaches to this concept are discussed in this paper. Firstly, the causes of the financial expansion that are synthesised in innovation, liquidification and deregulation processes are identified; secondly, the indicators concerning these processes relative to the structure of the balance sheet and profit and loss account of the main economic actors are empirically analysed for the Spanish case. The results of the analysis show a trend consistent with all capitalist economies, in which financial capital gains increase not only when the net profits of companies rise, but also when they collapse in a context of severe economic crisis and high unemployment. [ABSTRACT FROM AUTHOR]

Telomere length has been associated with the development of cancer. Studies have shown that shorter telomere length may be related to a decreased risk of cutaneous melanoma. Furthermore, deregulation of the telomere-maintaining gene complexes , has been related to this oncogenic process. Some variants in these genes seem to be correlated with a change in telomerase expression. We examined the effect of 10 single nucleotide polymorphisms (SNPs) in the TERT gene (encoding telomerase), one SNP in the related TERT-CLPTM1L locus and one SNP in the TRF1 gene with telomere length, and its influence on melanoma risk in 970 Spanish cases and 733 Spanish controls. Genotypes were determined using KASP technology, and telomere length was measured by quantitative polymerase chain reaction (PCR) on DNA extracted from peripheral blood leucocytes. Our results demonstrate that shorter telomere length is associated with a decreased risk of melanoma in our population (global p -value, 2.69 × 10 −11 ), which may be caused by a diminution of proliferative potential of nevi (melanoma precursor cells). We also obtained significant results when we tested the association between rs401681 variant ( TERT-CLPTM1L locus ) with melanoma risk (Odds ratio, OR; 95% confidence interval, CI = 1.24 (1.08–1.43); p -value, 3 × 10 −3 ). This is the largest telomere-related study undertaken in a Spanish population to date. Furthermore, this study represents a comprehensive analysis of some of the most relevant telomere pathway genes in relation to cutaneous melanoma susceptibility. [ABSTRACT FROM AUTHOR]

An information policy is a concerted action of various agents with information as the object, having as a purpose certain goals. The crisis we face is not only economic but also technological and due to changes in the organizational model, and we are already seeing some effects of deregulation and no planning. We can only establish solid information policies if we find a set of actions around which a wide spectrum of agents can be aligned without friction. 1. In the print world, policies should allow us to determine what exists and make that easily accessible, and know what is little used and will tend to be used less and ensure that it is preserved. 2. Research funding institutions can and must agree to facilitate open access to information and data. 3. Finally, the library-organization must be able to provide digital books, offer digital information that anybody can use, and ensure that born-digital materials are passed on to future generations. To this we must add the need to plan for information literacy training in schools. In these times of change, surrounded by uncertainty and some notable weaknesses, part of our professional duties should be devoted to elaborate agreements enabling us to take coordinated action in certain directions. [ABSTRACT FROM AUTHOR]

The Spanish healthcare system has undergone important changes, particularly with respect to the development of new hospital services. Today, more than ever, the factors that define the nature and structured of the Spanish healthcare environment (e.g. demand, costs, system deregulation) are undergoing rapid change thus obliging hospital administrators to develop and implement flexible and adaptive strategies in order to survive in an increasingly challenging environment facing hospital management. This work examines how the existence of some learning practices is linked to knowledge transfer and how this component is linked to relational capital. These relationships are examined through an empirical investigation of 54 doctors and 62 nurses belonging to 44 Hospital-in-the-Home Units. In an applied sense, the findings provide homecare practitioners with identifiable factors, which enable two learning models (conceptual and operational) and address the relevant issues by changing strategies at both the individual and organisational levels. [ABSTRACT FROM AUTHOR]

We examine price by season and by year in 14 deregulated markets, by looking at diurnal price patterns and price volatility. Power price volatility is measured by price velocity, the daily average of the absolute value of price change per hour, which is broken into a component expected from the average diurnal pattern, and an unexpected component. Deregulated markets can be categorized into three groups: stable markets, markets that experienced one bad period or season of high price excursion, and chaotic markets. Britain, Spain and Scandinavia show consistent price patterns and low unexpected price velocity; a thoughtful consumer could reasonably implement demand side management (DSM) by shaping consumption patterns to reflect price. California, New Zealand and Alberta are examples of markets that had a period of very high price excursion; we discuss factors affecting public reaction to this. Australian power markets have inconsistent price patterns from season to season and year to year, and very high unexpected price velocity. Planned DSM in these markets would be very difficult. We offer four policy considerations for markets considering deregulation in the future. [ABSTRACT FROM AUTHOR]

The Toxic Oil Syndrome (TOS) was a toxic epidemic disease, related to the consumption of rapeseed oil denatured with aniline that affected more than 20,000 people in Spain and resulted in more than 330 deaths after its sudden appearance in 1981. It has been reported that the fatty acid esters of 3-(N-phenylamino)-1,2-propanediol (PAP) have shown a strong association with TOS. These PAP-esters could be absorbed and metabolized in a similar way than phospholipids. This is of interest because some products of phospholipid metabolism are important mediators in downstream pathways involved in the regulation of different nuclear factors. In particular, phospholipase D activity is involved in the activation of c-fos. Thus, we have investigated the effect of different PAP-esters in the induction of c-fos in lung fibroblasts. Results indicate that PAP-esters rapidly induced the expression of c-fos in a dose–dependent manner. In addition, both butanol and propranolol prevent this induction pointing to the involvement of phospholipase D in this activation. These results suggest that deregulation of some nuclear factors such as AP-1 could be involved in the pathogenesis of TOS. [Copyright &y& Elsevier]

Provides an approach to measure technology transfer in Spain. Balance of technological receipt and expenditure at international level; Definition of international technology transfer; Legislative changes in economic relations and foreign trade; Deregulation of the technology market in Spain; Technological transfer among companies.

The deregulation of the electricity markets in the European Union and the transformation caused by digital technologies and customer-centric strategies have altered the industry ecosystem, forcing companies to adapt to the new scenario. This research study aims to give a global overview of the digital transformation and channel integration of free-market electricity retailers in Spain from a consumer's perspective. The analysis includes all free-market electricity retailers that operate at the national scale, explores the level of digital transformation and channel integration of these companies based on a structured set of indicators, and measures them using the mystery shopper technique. The results show important differences between leading retailers and the rest of companies, evidence an important lag of the sector when compared to other retail markets and an overall lack of multichannel and omnichannel strategies, show a strong effort of retailers in online billing and self-service customer data management, and reveal shortcomings in the availability of communication channels with customers. [ABSTRACT FROM AUTHOR]

Abstract: The aim of the European Commission''s Single European Sky initiative is to promote a series of structural changes within Air Transport to help improve its efficiency, continuity and sustainability. One of the key elements of the air transport system is Air Traffic Services (ATSs), which must guarantee safe and fluid operations. The Single European Sky initiative puts in place a series of mechanisms to replace the existing public monopolies with free market models. Taking advantage of this new framework, Spain has initiated a process of liberalisation of ATS Services, which may provide a business opportunity for operators with an interest in the area of air transport, and European providers who wish to expand their markets. This document sets out the new legal framework that has been put in place in Spain to promote this process, indicating the motives of these actions and the main implications the process will have, whilst maintaining the objective of guaranteeing continuity of service, and avoiding any barriers to entry, which changes of this type can give rise to. [Copyright &y& Elsevier]