1. Human papillomavirus prevalence in a Mid-European oral squamous cell cancer population: A cohort study
- Author
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Wolfgang Puelacher, Daniel Dalla Torre, Elisabeth Soelder, Doris Burtscher, Vincent Offermanns, and Michael Rasse
- Subjects
Male ,medicine.medical_specialty ,Alcohol Drinking ,Population ,Cohort Studies ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Internal medicine ,Prevalence ,medicine ,Humans ,Lack of knowledge ,Human papillomavirus ,education ,General Dentistry ,Aged ,education.field_of_study ,Squamous cell cancer ,business.industry ,Papillomavirus Infections ,Age Factors ,HPV infection ,virus diseases ,Cancer ,030206 dentistry ,Middle Aged ,medicine.disease ,female genital diseases and pregnancy complications ,Europe ,stomatognathic diseases ,Sexual Partners ,Otorhinolaryngology ,Oropharyngeal Carcinoma ,030220 oncology & carcinogenesis ,Tooth Extraction ,Carcinoma, Squamous Cell ,Female ,Mouth Neoplasms ,business ,Cohort study - Abstract
OBJECTIVES Human papillomavirus infection has been investigated intensively regarding oropharyngeal carcinoma. However, there is still lack of knowledge about the impact of oral HPV infections concerning oral squamous cell carcinoma. This study investigates the prevalence of oral HPV infection in such patients, identifying possible differences between HPV+ and HPV- patients. SUBJECTS AND METHODS One hundred and six consequent patients were investigated. After completion of a study questionnaire regarding risk factors, a brush smear sample was taken in each subject to identify the individual oral HPV status (overall/low risk/high risk). RESULTS About 35.8% of the patients were tested positive for HPV in the oral cavity (14% low risk, 28.3% high risk). Patients with oral HPV infection and high-risk HPV infection were significantly younger (p
- Published
- 2018
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