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1. Genome-wide schizophrenia variant at MIR137 does not impact white matter microstructure in healthy participants.

Author

Kelly, Sinead, Morris, Derek W., Mothersill, Omar, Rose, Emma Jane, Fahey, Ciara, O’Brien, Carol, O’Hanlon, Erik, Gill, Michael, Corvin, Aiden P., and Donohoe, Gary

Subjects
*MICRORNA, *MICROSTRUCTURE, *SCHIZOPHRENIA risk factors, *WHITE matter (Nerve tissue), *BRAIN physiology, *PUBLIC health
Abstract

Highlights: [•] We investigated the effect of a schizophrenia risk variant at MIR137 on white matter. [•] We conducted whole-brain TBSS and ROI tractography in 123 healthy participants. [•] No significant effect of MIR137 genotype on white matter was found. [•] This gene may not act alone for effects it may have on white matter in patients. [Copyright &y& Elsevier]

Published
2014
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