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1. A highly selective ratio-metric fluorescent sensor for visualizing nitroreductase in hypoxic cells.

Author

Xu, Yumei, Hu, Bing, Cui, Yanjun, Li, Li, Nian, Fang, Zhang, Zhixia, and Wang, Wenting

Subjects
DETECTORS, MOLECULAR probes, HYPOXEMIA
Abstract

Herein, we have developed a novel single-molecular probe (NORP) for selective and accurate determination of NTR in living cells. It was discovered that up-regulation of endogenous NTR occurred in response to hypoxic stimulation, and there was a dependence between the NTR levels and the degree of hypoxia. [ABSTRACT FROM AUTHOR]

Published
2024
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