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Tracing and isolation of close contacts is used to control outbreaks of coronavirus disease 2019 (COVID‐19) in China. However, risk factors associated with the occurrence of COVID‐19 among close contacts have not been well described. A total of 106 household contacts were included in this study, of whom 19 developed into COVID‐19 cases, and the secondary attack rate was 17.9%. Multivariable analysis showed that increasing risk of occurrence of COVID‐19 among household contacts was associated with female index patients (adjusted hazard ratio [aHR] = 3.84, 95% CI = 1.07–13.78), critical disease index patients (aHR = 7.58, 95% CI = 1.66–34.66), effective contact duration with index patients > 2 days (aHR = 4.21, 95% CI = 1.29–13.73), and effective contact duration > 11 days (aHR = 17.88, 95% CI = 3.26–98.01). The sex and disease severity of index patients with COVID‐19 and longer effective contact duration with patients with confirmed COVID‐19 could help epidemiologists to identify potential COVID‐19 cases among household contacts at an early stage. [ABSTRACT FROM AUTHOR]

Keywords: Isolation; quarantine; SARS-CoV-2; Beta variant; Alpha variant; COVID-19; transmission; international travel EN Isolation quarantine SARS-CoV-2 Beta variant Alpha variant COVID-19 transmission international travel 1 2 2 01/05/22 20211201 NES 211201 Quarantine of international travelers at arrival, often in specialized quarantine centers or hotels, is a measure frequently used by many countries to reduce the risk of importation.[1-2, 3] Evidence of the risk for transmission by contaminated environment or fomites via infected travellers from such quarantine facilities is lacking. Isolation, quarantine, SARS-CoV-2, Beta variant, Alpha variant, COVID-19, transmission, international travel Environmental surfaces from their quarantine rooms were sampled and tested for SARS-CoV-2, using the same methods as reported in a previous study.4 In total, 22 environmental samples collected from 11 sampling sites of each quarantine room were taken. [Extracted from the article]