13 results on '"Marsh, Nicole"'
Search Results
2. Risk factors for arterial catheter failure and complications during critical care hospitalisation: a secondary analysis of a multisite, randomised trial.
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Schults, Jessica A., Young, Emily R., Marsh, Nicole, Larsen, Emily, Corley, Amanda, Ware, Robert S., Murgo, Marghie, Alexandrou, Evan, McGrail, Matthew, Gowardman, John, Charles, Karina R., Regli, Adrian, Yasuda, Hideto, and Rickard, Claire M.
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ARTERIAL catheters ,SECONDARY analysis ,INTENSIVE care patients ,CATHETER-related infections ,CRITICAL care medicine ,SECONDARY care (Medicine) - Abstract
Objectives: Arterial catheters (ACs) are critical for haemodynamic monitoring and blood sampling but are prone to complications. We investigated the incidence and risk factors of AC failure. Methods: Secondary analysis of a multi-centre randomised controlled trial (ACTRN 12610000505000). Analysis included a subset of adult intensive care unit patients with an AC. The primary outcome was all-cause device failure. Secondary outcomes were catheter associated bloodstream infection (CABSI), suspected CABSI, occlusion, thrombosis, accidental removal, pain, and line fracture. Risk factors associated with AC failure were investigated using Cox proportional hazards and competing-risk models. Results: Of 664 patients, 173 (26%) experienced AC failure (incidence rate [IR] 37/1000 catheter days). Suspected CABSI was the most common failure type (11%; IR 15.3/1000 catheter days), followed by occlusion (8%; IR 11.9/1,000 catheter days), and accidental removal (4%; IR 5.5/1000 catheter days). CABSI occurred in 16 (2%) patients. All-cause failure and occlusion were reduced with ultrasound-assisted insertion (failure: adjusted hazard ratio [HR] 0.43, 95% CI 0.25, 0.76; occlusion: sub-HR 0.11, 95% CI 0.03, 0.43). Increased age was associated with less AC failure (60–74 years HR 0.63, 95% CI 0.44 to 0.89; 75 + years HR 0.36, 95% CI 0.20, 0.64; referent 15–59 years). Females experienced more occlusion (adjusted sub-HR 2.53, 95% CI 1.49, 4.29), while patients with diabetes had less (SHR 0.15, 95% CI 0.04, 0.63). Suspected CABSI was associated with an abnormal insertion site appearance (SHR 2.71, 95% CI 1.48, 4.99). Conclusions: AC failure is common with ultrasound-guided insertion associated with lower failure rates. Trial registration Australian New Zealand Clinical Trial Registry (ACTRN 12610000505000); date registered: 18 June 2010. [ABSTRACT FROM AUTHOR]
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- 2024
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3. Neonatal Vascular Access Practice and Complications.
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McIntyre, Colette, August, Deanne, Cobbald, Linda, Lack, Gill, Takashima, Mari, Foxcroft, Katie, Marsh, Nicole, Smith, Patricia, New, Karen, Koorts, Pieter, Irwin, Adam, and Ullman, Amanda
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STATISTICS ,BLOOD vessels ,CATHETER-related infections ,SCIENTIFIC observation ,CONFIDENCE intervals ,MULTIPLE regression analysis ,PEDIATRICS ,RISK assessment ,COMPARATIVE studies ,LOW birth weight ,CATHETERIZATION complications ,DESCRIPTIVE statistics ,PHYSICIAN practice patterns ,CATHETERIZATION ,DATA analysis software ,MEDICAL equipment ,CATHETERS ,LONGITUDINAL method ,PROPORTIONAL hazards models ,DISEASE risk factors ,CHILDREN - Abstract
Vascular access devices play vital roles within neonatal care. We aimed to identify neonatal vascular access device insertion and management practices, and describe the incidence and risk factors for complication development. This is a prospective cohort study of neonates requiring vascular access devices over 3 months in an Australian quaternary-referral neonatal intensive care unit. In addition to describing current practices, primary outcomes were device failure, complications, and skin complications. Results are reported using descriptive statistics and with risk factors calculated via Cox proportional hazards regression. A total of 104 neonates required 302 vascular access devices, over 1375 catheter days. Peripheral intravenous catheters (PIVCs) were most used (n = 186; 62%), followed by umbilical venous catheters (n = 52; 17%). Insertion attempts were often undocumented; but for those recorded, 5% of devices (n = 15) required 4 attempts or more. Device failure occurred in 28% (n = 82), at an incidence rate of 62.5 per 1000 catheter days (95% confidence interval [CI] 49.775.9). Failure was most frequent in PIVCs (37%; n = 68), peripheral arterial catheters (33%; n = 2), and peripherally inserted central catheters (20%; n = 6). Infiltration and extravasation were the most frequent cause of PIVC failure (12%; n = 35). A birth weight less than 1500 g was associated with a significant decrease in PIVC failure (hazard ratio 0.58; 95% CI 0.34-0.99). [ABSTRACT FROM AUTHOR]
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- 2023
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4. A novel integrated dressing to secure peripheral intravenous catheters in an adult acute hospital: a pilot randomised controlled trial
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Marsh, Nicole, Larsen, Emily, Genzel, Jodie, Mihala, Gabor, Ullman, Amanda J., Kleidon, Tricia, Cadigan, Sue, and Rickard, Claire M.
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- 2018
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5. Integrated versus non-integrated peripheral intravenous catheters: a cross-sectional survey of nurse experiences.
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Paterson, Rebecca S, Larsen, Emily N, Cooke, Marie, Rickard, Claire M, Walker, Rachel M, and Marsh, Nicole
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INTRAVENOUS catheterization ,RESEARCH ,CONSENSUS (Social sciences) ,HEALTH services accessibility ,HEALTH facilities ,BLOOD vessels ,CONFIDENCE ,CATHETER-related infections ,CROSS-sectional method ,SATISFACTION ,PATIENT-centered care ,RANDOMIZED controlled trials ,SURVEYS ,COMPARATIVE studies ,T-test (Statistics) ,NURSES ,DESCRIPTIVE statistics ,CHI-squared test ,RESEARCH funding ,INTEGRATED health care delivery ,STATISTICAL sampling ,JUDGMENT sampling ,DATA analysis software ,THEMATIC analysis ,MEDICAL needs assessment ,EVIDENCE-based nursing ,MEDICAL equipment - Abstract
Background: Integrated peripheral intravenous catheters (PIVCs) demonstrate clinical efficacy, however, device complexity and design differences may be a potential barrier to implementation. Aims: To assess nurse acceptability of integrated PIVC systems. Methods: A cross-sectional survey was nested within a multicentre randomised controlled trial. One hundred nurses caring for patients with integrated and non-integrated PIVCs completed a 17-item survey about key differences between devices (eg function and appearance, perceived patient comfort and skin injuries). Findings: Most nurses reported the integrated PIVC wings prevented device movement (80%), achieved patient comfort in areas of flexion (78%), and no patients developed skin injuries (100%). Nurses rated the ease of accessing and overall confidence using the integrated PIVC as significantly higher than the non-integrated design (P<0.001).Conclusion: The integrated PIVC received positive feedback from nurses and had few barriers to implementation. [ABSTRACT FROM AUTHOR]
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- 2023
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6. Effect of infusion set replacement intervals on catheter-related bloodstream infections (RSVP): a randomised, controlled, equivalence (central venous access device)-non-inferiority (peripheral arterial catheter) trial.
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Rickard, Claire M, Marsh, Nicole M, Larsen, Emily N, McGrail, Matthew R, Graves, Nicholas, Runnegar, Naomi, Webster, Joan, Corley, Amanda, McMillan, David, Gowardman, John R, Long, Debbie A, Fraser, John F, Gill, Fenella J, Young, Jeanine, Murgo, Marghie, Alexandrou, Evan, Choudhury, Md Abu, Chan, Raymond J, Gavin, Nicole C, and Daud, Azlina
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CATHETER-related infections , *ARTERIAL catheters , *PERIPHERALLY inserted central catheters , *ADVERSE health care events , *CLINICAL trial registries , *PARENTERAL feeding , *MEDICAL personnel - Abstract
Background: The optimal duration of infusion set use to prevent life-threatening catheter-related bloodstream infection (CRBSI) is unclear. We aimed to compare the effectiveness and costs of 7-day (intervention) versus 4-day (control) infusion set replacement to prevent CRBSI in patients with central venous access devices (tunnelled cuffed, non-tunnelled, peripherally inserted, and totally implanted) and peripheral arterial catheters.Methods: We did a randomised, controlled, assessor-masked trial at ten Australian hospitals. Our hypothesis was CRBSI equivalence for central venous access devices and non-inferiority for peripheral arterial catheters (both 2% margin). Adults and children with expected greater than 24 h central venous access device-peripheral arterial catheter use were randomly assigned (1:1; stratified by hospital, catheter type, and intensive care unit or ward) by a centralised, web-based service (concealed before allocation) to infusion set replacement every 7 days, or 4 days. This included crystalloids, non-lipid parenteral nutrition, and medication infusions. Patients and clinicians were not masked, but the primary outcome (CRBSI) was adjudicated by masked infectious diseases physicians. The analysis was modified intention to treat (mITT). This study is registered with the Australian New Zealand Clinical Trials Registry ACTRN12610000505000 and is complete.Findings: Between May 30, 2011, and Dec, 9, 2016, from 6007 patients assessed, we assigned 2944 patients to 7-day (n=1463) or 4-day (n=1481) infusion set replacement, with 2941 in the mITT analysis. For central venous access devices, 20 (1·78%) of 1124 patients (7-day group) and 16 (1·46%) of 1097 patients (4-day group) had CRBSI (absolute risk difference [ARD] 0·32%, 95% CI -0·73 to 1·37). For peripheral arterial catheters, one (0·28%) of 357 patients in the 7-day group and none of 363 patients in the 4-day group had CRBSI (ARD 0·28%, -0·27% to 0·83%). There were no treatment-related adverse events.Interpretation: Infusion set use can be safely extended to 7 days with resultant cost and workload reductions.Funding: Australian National Health and Medical Research Council. [ABSTRACT FROM AUTHOR]- Published
- 2021
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7. Peripheral intravenous catheter infection and failure: A systematic review and meta-analysis.
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Marsh, Nicole, Larsen, Emily N., Ullman, Amanda J., Mihala, Gabor, Cooke, Marie, Chopra, Vineet, Ray-Barruel, Gillian, and Rickard, Claire M.
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INTRAVENOUS catheterization , *MEDICAL databases , *ONLINE information services , *CINAHL database , *CATHETER-related infections , *META-analysis , *MEDICAL information storage & retrieval systems , *CONFIDENCE intervals , *SYSTEMATIC reviews , *DISEASE incidence , *RISK assessment , *CATHETERIZATION complications , *DESCRIPTIVE statistics , *MEDLINE , *VASCULAR catheters , *DISEASE risk factors - Abstract
Peripheral intravenous catheters are the most frequently used invasive device in nursing practice, yet are commonly associated with complications. We performed a systematic review to determine the prevalence of peripheral intravenous catheter infection and all-cause failure. The Cochrane Library, PubMed, CINAHL, and EMBASE were searched for observational studies and randomised controlled trials that reported peripheral intravenous catheter related infections or failure. The review was limited to English language and articles published from the year 2000. Pooled estimates were calculated with random-effects models. Meta-analysis of observation studies in epidemiology guidelines and the Cochrane process for randomised controlled trials were used to guide the review. Prospero registration number: CRD42022349956. Our search retrieved 34,725 studies. Of these, 41 observational studies and 28 randomised controlled trials (478,586 peripheral intravenous catheters) met inclusion criteria. The pooled proportion of catheter-associated bloodstream infections was 0.028 % (95 % confidence interval (CI): 0.009–0.081; 38 studies), or 4.40 catheter-associated bloodstream infections per 100,000 catheter-days (20 studies, 95 % CI: 3.47–5.58). Local infection was reported in 0.150 % of peripheral intravenous catheters (95 % CI: 0.047–0.479, 30 studies) with an incidence rate of 65.1 per 100,000 catheter-days (16 studies; 95 % CI: 49.2–86.2). All cause peripheral intravenous catheter failure before treatment completion occurred in 36.4 % of catheters (95 % CI: 31.7–41.3, 53 studies) with an overall incidence rate of 4.42 per 100 catheter days (78,891 catheter days; 19 studies; 95 % CI: 4.27–4.57). Peripheral intravenous catheter failure is a significant worldwide problem, affecting one in three catheters. Per peripheral intravenous catheter, infection occurrence was low, however, with over two billion catheters used globally each year, the absolute number of infections and associated burden remains high. Substantial and systemwide efforts are needed to address peripheral intravenous catheter infection and failure and the sequelae of treatment disruption, increased health costs and poor patient outcomes. [ABSTRACT FROM AUTHOR]
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- 2024
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8. Evaluation of Skin Colonisation And Placement of vascular access device Exit sites (ESCAPE Study).
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Moureau, Nancy L., Marsh, Nicole, Zhang, Li, Bauer, Michelle J., Larsen, Emily, Mihala, Gabor, Corley, Amanda, Lye, India, Cooke, Marie, and Rickard, Claire M.
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PREVENTION of bloodborne infections , *SKIN microbiology , *CATHETER-related infections , *BLOOD vessels , *CHI-squared test , *CONFIDENCE intervals , *HOST-bacteria relationships , *MEDICAL equipment , *RESEARCH funding , *STATISTICAL sampling , *LOGISTIC regression analysis , *ODDS ratio , *COLONY-forming units assay , *INFECTION prevention - Abstract
Background: Skin microorganisms may contribute to the development of vascular access device (VAD) infections. Baseline skin microorganism type and quantity vary between body sites, yet there is little evidence to inform choice of VAD site selection. Objective: To compare microorganisms present at different body sites used for VAD insertions and understand the effect of transparent dressings on skin microflora. Methods: The ESCAPE observational study consisted of three phases: (1) skin swabs of four sites (mid-neck, base neck, chest, upper arm) from 48 hospital patients; (2) skin swabs of five body sites (mid-neck, base neck, chest, upper arm, lower arm) from 10 healthy volunteers; and (3) paired skin swabs (n = 72) under and outside of transparent dressings from 36 hospital patients (16 mid/base neck, 10 chest, upper arm). Specimens were cultured for 72 h, species identified and colony-forming units (CFU) counted. Ordinal logistic regression compared CFU categories between variables of interest. Results: The chest and upper arm were significantly associated with fewer microorganisms compared to neck or forearm (odds ratio [OR] = 0.40, 95% confidence interval [CI] = 0.25–0.65, P < 0.05). CFU levels under transparent dressings were not significantly different from outside (OR = 0.57, 95% CI = 0.22–1.45). Staphylococci were predominant at all sites. Other significant (P < 0.05) predictors of higher CFU count included prolonged hospitalisation and medical/surgical patient status. Discussion: Skin microorganism load was significantly lower at the upper arm or chest, compared to the mid- or base neck. This may impact VAD site selection and subsequent infection risk. [ABSTRACT FROM AUTHOR]
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- 2019
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9. Central venous Access device SeCurement And Dressing Effectiveness for peripherally inserted central catheters in adult acute hospital patients (CASCADE): a pilot randomised controlled trial.
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Chan, Raymond J., Northfield, Sarah, Larsen, Emily, Mihala, Gabor, Ullman, Amanda, Hancock, Peter, Marsh, Nicole, Gavin, Nicole, Wyld, David, Allworth, Anthony, Russell, Emily, Choudhury, Md Abu, Flynn, Julie, and Rickard, Claire M.
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CATHETER-related infections ,PERIPHERALLY inserted central catheters ,PERIPHERAL central venous catheterization ,SURGICAL dressings ,NOSOCOMIAL infections ,BACTERICIDES ,ADHESIVES in surgery ,ATTITUDE (Psychology) ,CATHETERS ,CHLORHEXIDINE ,COMPARATIVE studies ,HOSPITAL patients ,INTRAVENOUS catheterization ,RESEARCH methodology ,MEDICAL cooperation ,MEDICAL personnel ,PATIENT satisfaction ,POLYURETHANES ,RESEARCH ,TIME ,PILOT projects ,PRODUCT design ,EVALUATION research ,RANDOMIZED controlled trials ,TREATMENT effectiveness ,CENTRAL venous catheterization ,MEDICAL equipment reliability ,MEDICAL device removal ,CENTRAL venous catheters ,EQUIPMENT & supplies ,DIAGNOSIS ,THERAPEUTICS ,INFECTION prevention - Abstract
Background: Peripherally inserted central catheters (PICCs) are commonly used for delivering intravenous therapy. PICC failure is unacceptably high (up to 40%) due to mechanical, infectious and thrombotic complications. Poor securement potentiates all complication types. This randomised controlled trial (RCT) aimed to examine the feasibility of a large RCT of four dressing and securement methods to prevent PICC failure.Methods: This single-centre pilot RCT included 124 admitted medical/surgical/cancer patients aged ≥ 16 years with a PICC. Interventions were: (i) standard polyurethane dressing and sutureless securement device (SPU + SSD, control); (ii) polyurethane with absorbent lattice pad dressing (PAL + Tape); (iii) combination securement-dressing (CSD); and (iv) tissue adhesive (TA + SPU). All groups except TA + SPU had a chlorhexidine-gluconate (CHG) impregnated disc. Feasibility outcomes were recruitment and safety/acceptability of the interventions. The primary outcome was PICC failure, a composite of PICC removal for local infection, catheter-associated bloodstream infection, dislodgement, occlusion, and/or catheter fracture. Secondary outcomes included individual complications, dressing failure and dwell time, PICC dwell time, skin complications/phlebitis indicators, product costs, and patient and staff satisfaction. Qualitative feedback was also collected.Results: PICC failure incidence was: PAL + CHG + Tape (1/5; 20%; 17.4/1000 days), SPU + SSD + CHG (control) (4/39; 10%; 9.0/1000 days), TA + SPU (3/35; 9%; 9.6/1000 days), and CSD + CHG (3/42; 7%; 9.4/1000 days). Recruitment to PAL + CHG + Tape was ceased after five participants due to concerns of PICC dislodgement when removing the dressing. CSD + CHG, TA + SPU (TA applied only at PICC insertion time), and control treatments were acceptable to patients and health professionals.Conclusion: A large RCT of CSD + CHG and TA + SPU (but not PAL + CHG + Tape) versus standard care is feasible.Trial Registration: Australian and New Zealand Clinical Trials Registry, ACTRN12616000027415 . Registered on 15 January 2016. [ABSTRACT FROM AUTHOR]- Published
- 2017
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10. Devices and dressings to secure peripheral venous catheters: A Cochrane systematic review and meta-analysis.
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Marsh, Nicole, Webster, Joan, Mihala, Gabor, and Rickard, Claire M.
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INTRAVENOUS catheterization , *VASCULAR catheters , *ADHESIVE tape , *ADHESIVES , *CINAHL database , *COMMERCIAL product evaluation , *COMPARATIVE studies , *CONFIDENCE intervals , *INFORMATION storage & retrieval systems , *MEDICAL databases , *MEDICAL information storage & retrieval systems , *MEDLINE , *META-analysis , *PHLEBITIS , *SURGICAL dressings , *TRANSPARENCY (Optics) , *SYSTEMATIC reviews , *RANDOMIZED controlled trials , *EXTRAVASATION , *EQUIPMENT & supplies , *SAFETY - Abstract
Background Peripheral venous catheterisation is the most frequent invasive procedure performed in hospitalised patients; yet over 30% of peripheral venous catheters fail before treatment ends. Objectives To assess the effects of peripheral venous catheter dressings and securement devices on the incidence of peripheral venous catheter failure. Data sources We searched the Cochrane Wounds Group Register, The Cochrane Central Register of Controlled Trials, MEDLINE; EMBASE and CINAHL for any randomised controlled trials comparing different dressings or securement devices used to stabilise peripheral venous catheters. The reference lists of included studies were also searched for any previously unidentified studies. Results We included six randomised controlled trials (1539 participants) that compared various dressings and securement devices (transparent dressings versus gauze; bordered transparent dressings versus a securement device; bordered transparent dressings versus tape; and transparent dressing versus sticking plaster). Trial sizes ranged from 50 to 703 participants. The quality of evidence ranged from low to very low. Catheter dislodgements or accidental removals were lower with transparent dressings compared with gauze (two studies, 278 participants, risk ratio (RR) 0.40; 95% confidence interval (CI) 0.17–0.92, P = 0.03%). However, the relative effects of transparent dressings and gauze on phlebitis (RR 0.89; 95% CI 0.47–1.68) and infiltration (RR 0.80; 95% CI 0.48–1.33) are unclear. A single study identified less frequent dislodgement or accidental catheter removal with bordered transparent dressings compared to a securement device (RR 0.14, 95% CI 0.03–0.63) but more phlebitis with bordered dressings (RR 8.11, 95% CI 1.03–64.02). A comparison of a bordered transparent dressing and tape found more peripheral venous catheter failure with the bordered dressing (RR 1.84, 95% CI 1.08–3.11) but the relative effect on dislodgement was unclear. Conclusions There is no strong evidence to suggest that any one dressing or securement product for preventing peripheral venous catheter failure is more effective than any other product. All of the included trials were small, had high or unclear risk of bias for one or more of the quality elements we assessed, and wide confidence intervals, indicating that further randomised controlled trials are necessary. There is a need for suitably powered, high quality trials to evaluate the newer, high use products and novel – but expensive – securement methods, such as surgical grade glue. [ABSTRACT FROM AUTHOR]
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- 2017
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11. Infection risks associated with peripheral vascular catheters.
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Zhang, Li, Cao, Siyu, Marsh, Nicole, Ray-Barruel, Gillian, Flynn, Julie, Larsen, Emily, and Rickard, Claire M.
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PREVENTION of bloodborne infections ,CATHETER-related infections ,PREVENTION of communicable diseases ,INTRAVENOUS catheterization ,PATIENT safety ,UNIVERSAL precautions (Health) ,INFECTION prevention - Abstract
Background: Peripheral vascular catheters (PVC) are the most frequently used invasive medical devices in hospitals, with 330 million sold each year in the USA alone. One in three UK inpatients at any one time has at least one PVC in situ according to the Scottish National Prevalence survey. Method: A narrative review of studies describing the infection risks associated with PVCs. Results: It is estimated that 30–80% of hospitalised patients receive at least one PVC during their hospital stay. Despite their prevalence, PVCs are not benign devices, and the high number of PVCs inserted annually has resulted in serious catheter-related bloodstream infections and significant morbidity, prolonged hospital stay and increased healthcare system costs. To date, PVC infections have been under-evaluated. Most studies focus on central venous catheter rather than PVC-associated bloodstream infections. Risks associated with PVC infection must be addressed to reduce patient morbidity and associated costs of prolonged hospital admission and treatment. Discussion: This article discusses the sources and routes of PVC-associated infection and outlines known effective prevention and intervention strategies. [ABSTRACT FROM AUTHOR]
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- 2016
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12. Intravascular device use, management, documentation and complications: a point prevalence survey.
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New, Karen A., Webster, Joan, Marsh, Nicole M., and Hewer, Barbara
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BLOOD vessels ,DOCUMENTATION ,EPIDEMIOLOGICAL research ,IRRIGATION (Medicine) ,MEDICAL equipment ,PUBLIC health surveillance ,QUESTIONNAIRES ,SURVEYS ,DISEASE prevalence ,CENTRAL venous catheterization ,DATA analysis software ,VASCULAR catheters ,DESCRIPTIVE statistics ,CATHETER-related infections ,TERTIARY care ,SAFETY ,INFECTION prevention - Abstract
Objective. To examine the use, management, documentation and complications for intravascular devices in cardiac, medical and surgical inpatients. Methods. A point prevalence survey was undertaken in a large tertiary hospital in Queensland. Descriptive statistics were used to analyse data. Results. Of the 327 patients assessed, 192 (58.7%) had one or more devices in situ. Of the 220 devices, 190 (86.4%) were peripheral venous catheters, 25 (11.4%) were peripherally inserted central catheters and five (2.3%) were central venous catheters. Sixty-two of 220 devices (28.2%) were in situ without a clear purpose, whereas 54 (24.7%) had one or more complications, such as redness, pain, tracking, oedema or oozing. There was no documentation on the daily patient care record to indicate that a site assessment had occurred within the past 8 h for 25% of the devices in situ. Conclusions. The present study identified several problems and highlighted areas for improvement in the management and documentation for intravascular devices. Ongoing education, promoting good clinical practice and reauditing, can be applied to improve the management of devices. [ABSTRACT FROM AUTHOR]
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- 2014
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13. Midline catheters — A good alternative device?
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Marsh, Nicole, Corley, Amanda, Schults, Jessica A., Vemuri, Kanti, and Rickard, Claire M.
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CATHETERS , *CATHETER-related infections , *ARTERIAL catheterization - Published
- 2021
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