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5. Prediction of Outcome and Endovascular Treatment Benefit

Author

Venema, Esmee, Roozenbeek, Bob, Mulder, Maxim JHL, Brown, Scott, Majoie, Charles BLM, Steyerberg, Ewout W, Demchuk, Andrew M, Muir, Keith W, Dávalos, Antoni, Mitchell, Peter J, Bracard, Serge, Berkhemer, Olvert A, Lycklama à Nijeholt, Geert J, van Oostenbrugge, Robert J, Roos, Yvo BWEM, van Zwam, Wim H, van der Lugt, Aad, Hill, Michael D, White, Philip, Campbell, Bruce CV, Guillemin, Francis, Saver, Jeffrey L, Jovin, Tudor G, Goyal, Mayank, Dippel, Diederik WJ, Lingsma, Hester F, der Lugt, Aad van, Boiten, Jelis, Vos, Jan Albert, Jansen, Ivo GH, Goldhoorn, Robert-Jan B, Compagne, Kars CJ, Kappelhof, Manon, Brouwer, Josje, den Hartog, Sanne J, Hinsenveld, Wouter H, van Es, Adriaan CGM, Emmer, Bart J, Coutinho, Jonathan M, Schonewille, Wouter J, Wermer, Marieke JH, van Walderveen, Marianne AA, Staals, Julie, Hofmeijer, Jeannette, Martens, Jasper M, de Bruijn, Sebastiaan F, van Dijk, Lukas C, van der Worp, H Bart, Lo, Rob H, van Dijk, Ewoud J, Boogaarts, Hieronymus D, Vries, J de, de Kort, Paul LM, van Tuijl, Julia, Peluso, Jo P, Fransen, Puck, van den Berg, Jan SP, van Hasselt, Boudewijn AAM, Aerden, Leo AM, Dallinga, René J, Uyttenboogaart, Maarten, Eschgi, Omid, Bokkers, Reinoud PH, Schreuder, Tobien HCML, Heijboer, Roel JJ, Keizer, Koos, Yo, Lonneke SF, den Hertog, Heleen M, Bulut, Tomas, Brouwers, Paul JAM, Sprengers, Marieke ES, Jenniskens, Sjoerd FM, van den Berg, René, Yoo, Albert J, Beenen, Ludo FM, Postma, Alida A, Roosendaal, Stefan D, van der Kallen, Bas FW, van den Wijngaard, Ido R, Bot, Joost, van Doormaal, Pieter-Jan, Meijer, Anton, Ghariq, Elyas, van Proosdij, Marc P, Krietemeijer, G Menno, Lo, Rob, Gerrits, Dick, Dinkelaar, Wouter, and Appelman, Auke PA

Subjects
Clinical Trials and Supportive Activities, Clinical Research, Stroke, Brain Disorders, Neurosciences, Aged, Aged, 80 and over, Brain Ischemia, Endovascular Procedures, Humans, Ischemic Stroke, Male, Middle Aged, Registries, Thrombectomy, Treatment Outcome, ischemic stroke, registry, reperfusion, thrombectomy, uncertainty, HERMES collaborators and MR CLEAN Registry Investigators*, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Neurology & Neurosurgery
Abstract

Background and purposeBenefit of early endovascular treatment (EVT) for ischemic stroke varies considerably among patients. The MR PREDICTS decision tool, derived from MR CLEAN (Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands), predicts outcome and treatment benefit based on baseline characteristics. Our aim was to externally validate and update MR PREDICTS with data from international trials and daily clinical practice.MethodsWe used individual patient data from 6 randomized controlled trials within the HERMES (Highly Effective Reperfusion Evaluated in Multiple Endovascular Stroke Trials) collaboration to validate the original model. Then, we updated the model and performed a second validation with data from the observational MR CLEAN Registry. Primary outcome was functional independence (defined as modified Rankin Scale score 0–2) 3 months after stroke. Treatment benefit was defined as the difference between the probability of functional independence with and without EVT. Discriminative performance was evaluated using a concordance (C) statistic.ResultsWe included 1242 patients from HERMES (633 assigned to EVT, 609 assigned to control) and 3156 patients from the MR CLEAN Registry (all of whom underwent EVT within 6.5 hours). The C-statistic for functional independence was 0.74 (95% CI, 0.72–0.77) in HERMES and, after model updating, 0.80 (0.78–0.82) in the Registry. Median predicted treatment benefit of routinely treated patients (Registry) was 10.3% (interquartile range, 5.8%–14.4%). Patients with low (

Published
2021

6. Breaching and liquefaction in subaqueous retrogressive flow slides

Author

van den Ham, Geeralt A., De Groot, Maarten B., Mastbergen, Dick R., and Van den Berg, Jan H.

Subjects
Slopes (Physical geography) -- Environmental aspects, Soil liquefaction -- Models -- Environmental aspects, Landslides -- Environmental aspects -- Models -- Netherlands, Stability -- Models, Earth sciences
Abstract

Although retrogressive flow slides in subaqueous sandy slopes can be very large and cause substantial damage, the failure mechanisms of such slides are not very clear yet. This study analyses two well-monitored flow slides in a shoal margin in the Western Scheldt estuary in the Netherlands: a natural flow slide that eroded 300 m into the edge of the shoal and an artificially induced flow slide that was triggered by dredging and eroded only 30 m of the shoal margin. Both slides were simulated with a newly developed numerical model that describes the physics of slow retrogressive breaching and the much faster retrogression of statically liquefied fine to medium (silty) sands. The simulations show that the differences in trigger and size can be explained by assuming that in the larger slide both retrogressive breaching and static liquefaction took place, while in the smaller one only breaching occurred. The main contribution of retrogressive liquefaction to the larger slide was the generation of a temporary high-erosive density flow that proved sufficient to create such a high, near-vertical slope that the breaching process could continue over a long period and distance. It is therefore likely that both breaching and static liquefaction play a role in large natural flow slides. Key words: flow slide, retrogressive breaching, static liquefaction, numerical model, subaqueous slope instability, 1. Introduction This paper deals with subaqueous flow slides in fine to medium (silty) sands that may include thin, discontinuous mud layers. Such flow slides may encompass several million cubic [...]

Published
2023
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7. Prognostic Value of Thrombus Volume and Interaction With First-Line Endovascular Treatment Device Choice

Author

van Voorst, Henk, Bruggeman, Agnetha A.E., Andriessen, Jurr, Hoving, Jan W., Konduri, Praneeta R., Yang, Wenjin, Kappelhof, Manon, Arrarte Terreros, Nerea, Roos, Yvo B.W.E.M., van Zwam, Wim H., van der Lugt, Aad, van der Hoorn, Anouk, Boiten, Jelis, Roosendaal, Stefan, Jenniskens, Sjoerd, Caan, Matthan W.A., Marquering, Henk A., Emmer, Bart J., Majoie, Charles B.L.M., Dippel, Diederik W.J., van Oostenbrugge, Robert J., Vos, Jan Albert, Jansen, Ivo G.H., Mulder, Maxim J.H.L., Goldhoorn, Robert- Jan B., Compagne, Kars C.J., Brouwer, Josje, den Hartog, Sanne J., Hinsenveld, Wouter H., Dippel, Diederik W.J., Roozenbeek, Bob, van Es, Adriaan C.G.M., Coutinho, Jonathan M., Schonewille, Wouter J., Vos, Jan Albert, Wermer, Marieke J.H., van Walderveen, Marianne A.A., Staals, Julie, van Oostenbrugge, Robert J., Hofmeijer, Jeannette, Martens, Jasper M., Lycklama à Nijeholt, Geert J., de Bruijn, Sebastiaan F., van Dijk, Lukas C., van der Worp, H. Bart, Lo, Rob H., van Dijk, Ewoud J., Boogaarts, Hieronymus D., de Vries, J., de Kort, Paul L.M., van Tuijl, Julia, Peluso, Jo P., Fransen, Puck, van den Berg, Jan S.P., van Hasselt, Boudewijn A.A.M., Aerden, Leo A.M., Dallinga, René J., Uyttenboogaart, Maarten, Eschgi, Omid, Bokkers, Reinoud P.H., Schreuder, Tobien H.C.M.L., Heijboer, Roel J.J., Keizer, Koos, Yo, Lonneke S.F., den Hertog, Heleen M., Sturm, Emiel J.C., Brouwers, Paul J.A.M., Lycklama à Nijeholt, Geert J., van Walderveen, Marianne A.A., Sprengers, Marieke E.S., van den Berg, René, Yoo, Albert J., Beenen, Ludo F.M., Postma, Alida A., van der Kallen, Bas F.W., van den Wijngaard, Ido R., van Es, Adriaan C.G.M., Martens, Jasper M., Yo, Lonneke S.F., Vos, Jan Albert, Bot, Joost, van Doormaal, Pieter-Jan, Meijer, Anton, Ghariq, Elyas, Bokkers, Reinoud P.H., van Proosdij, Marc P., Krietemeijer, G. Menno, Peluso, Jo P., Boogaarts, Hieronymus D., Lo, Rob, Gerrits, Dick, Dinkelaar, Wouter, Appelman, Auke P.A., Hammer, Bas, Pegge, Sjoert, Vinke, Saman, Dippel, Diederik W.J., van Oostenbrugge, Robert J., Lycklama à Nijeholt, Geert J., Vos, Jan Albert, Schonewille, Wouter J., Hofmeijer, Jeannette, Martens, Jasper M., van der Worp, H. Bart, Lo, Rob H., van Oostenbrugge, Robert J., Hofmeijer, Jeannette, Flach, H. Zwenneke, Lingsma, Hester F., el Ghannouti, Naziha, Sterrenberg, Martin, Pellikaan, Wilma, Sprengers, Rita, Elfrink, Marjan, Simons, Michelle, Vossers, Marjolein, de Meris, Joke, Vermeulen, Tamara, Geerlings, Annet, van Vemde, Gina, Simons, Tiny, Messchendorp, Gert, Nicolaij, Nynke, Bongenaar, Hester, Bodde, Karin, Kleijn, Sandra, Lodico, Jasmijn, Droste, Hanneke, Wollaert, Maureen, Verheesen, Sabrina, Jeurrissen, D., Bos, Erna, Drabbe, Yvonne, Sandiman, Michelle, Aaldering, Nicoline, Zweedijk, Berber, Vervoort, Jocova, Ponjee, Eva, Romviel, Sharon, Kanselaar, Karin, Barning, Denn, Venema, Esmee, Chalos, Vicky, Geuskens, Ralph R., van Straaten, Tim, Ergezen, Saliha, Harmsma, Roger R.M., Muijres, Daan, de Jong, Anouk, Berkhemer, Olvert A., Boers, Anna M.M., Huguet, J., Groot, P.F.C., Mens, Marieke A., van Kranendonk, Katinka R., Treurniet, Kilian M., Tolhuisen, Manon L., Alves, Heitor, Weterings, Annick J., Kirkels, Eleonora L.F., Voogd, Eva J.H.F., Schupp, Lieve M., Collette, Sabine, Groot, Adrien E.D., LeCouffe, Natalie E., Prasetya, Haryadi, and Ramos, Lucas A.

Published
2023
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9. Biomarker guided antibiotic stewardship in community acquired pneumonia: A randomized controlled trial.

Author

Duijkers, Ruud, Prins, Hendrik J., Kross, Martijn, Snijders, Dominic, van den Berg, Jan W. K., Werkman, Gwendolyn M., van der Veen, Nynke, Schoorl, Marianne, Bonten, Marc J. M., van Werkhoven, Cornelis H., and Boersma, Wim G.

Subjects
COMMUNITY-acquired pneumonia, C-reactive protein, RANDOMIZED controlled trials, ANTIMICROBIAL stewardship, TEACHING hospitals
Abstract

Background: In community-acquired pneumonia (CAP), the role of biomarkers to shorten duration of antibiotic treatment has not been firmly established. We assessed the effectiveness of active feedback of treatment algorithms based on procalcitonin (PCT) and C-reactive protein (CRP), compared to standard care, on the duration of antibiotic treatment in patients hospitalized with community-acquired pneumonia (CAP) in non-ICU wards. Methods and findings: We performed a randomised, open label, parallel group, multi-centre trial in 3 Dutch teaching hospitals. Treatment was guided by a PCT algorithm, CRP algorithm or standard care. Participants were recruited by a member of the study team and randomised at day 2–3 of admission in a 1:1:1 ratio. Treatment was discontinued upon predefined thresholds of biomarkers that were assessed on admission, day 4 and days 5–7 if indicated. The primary outcome was total days on antibiotic treatment until day 30. In total 468 participants were included in this study. The median days on antibiotics (IQR) was 7 (IQR 7–10) in the control group, 4 (IQR 3–7) in the CRP group (rate ratio (RR) of 0.70, 95% CI 0.61–0.82 compared to standard care; p <0.001), and 5.5 (IQR 3–9) in the PCT group (RR of 0.78, 95% CI 0.68–0.89 compared to standard care; p <0.001). New antibiotics within the first 30 days were prescribed to 24, 23 and 35 patients in standard care, CRP and PCT groups, respectively. The hazard ratio for a new prescription in patients in the PCT group compared to standard care 1.63 (CI 0.97–2.75; p = 0.06). No difference in time to clinical stability or length of stay was found. Conclusions: A strategy of feedback of CRP-guided and PCT-guided treatment algorithms reduced the number of days on antibiotic in the first 30 days after hospital admission in non-ICU wards for CAP. The study was not powered to determine safety of shortening duration of antibiotic treatment. (NCT01964495). [ABSTRACT FROM AUTHOR]

Published
2024
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12. Economic Evaluation of Endovascular Treatment for Acute Ischemic Stroke

Author

van den Berg, Lucie A., Berkhemer, Olvert A., Fransen, Puck S.S., Beumer, Debbie, Lingsma, Hester, Majoie, Charles B.M., Dippel, Diederik W.J., van der Lugt, Aad, van Oostenbrugge, Robert J., van Zwam, Wim H., Roos, Yvo B., Dijkgraaf, Marcel G.W., Yoo, Albert J., Schonewille, Wouter J., Vos, Jan Albert, Nederkoorn, Paul J., Wermer, Marieke J.H., van Walderveen, Marianne A.A., Staals, Julie, Hofmeijer, Jeannette, van Oostayen, Jacques A., Lycklama à Nijeholt, Geert J., Boiten, Jelis, Brouwer, Patrick A., Emmer, Bart J., de Bruijn, Sebastiaan F., van Dijk, Lukas C., Kappelle, L. Jaap, Lo, Rob H., van Dijk, Ewoud J., de Vries, Joost, de Kort, Paul L.M., van den Berg, Jan S.P., van Hasselt, Boudewijn A.A.M., Aerden, Leo A.M., Dallinga, René J., Visser, Marieke C., Bot, Joseph C.J., Vroomen, Patrick C., Eshghi, Omid, Schreuder, Tobien H.C.M.L., Heijboer, Roel J.J., Keizer, Koos, Tielbeek, Alexander V., den Hertog, Heleen M., Gerrits, Dick G., van den Berg-Vos, Renske M., Karas, Giorgos B., Steyerberg, Ewout W., Flach, H. Zwenneke, Marquering, Henk A., Sprengers, Marieke E.S., Jenniskens, Sjoerd F.M., Beenen, Ludo F.M., van den Berg, René, and Koudstaal, Peter J.

Published
2021
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13. Consensus goals and standards for specialist cough clinics: the NEUROCOUGH international Delphi study

Author

Song, Woo-Jung, primary, Dupont, Lieven, additional, Birring, Surinder S., additional, Chung, Kian Fan, additional, Dąbrowska, Marta, additional, Dicpinigaitis, Peter, additional, Ribas, Christian Domingo, additional, Fontana, Giovanni, additional, Gibson, Peter G., additional, Guilleminault, Laurent, additional, Hull, James H., additional, Idzko, Marco, additional, Kardos, Peter, additional, Kim, Hyun Jung, additional, Lai, Kefang, additional, Lavorini, Federico, additional, Millqvist, Eva, additional, Morice, Alyn H., additional, Niimi, Akio, additional, Parker, Sean M., additional, Satia, Imran, additional, Smith, Jaclyn A., additional, van den Berg, Jan Willem, additional, and McGarvey, Lorcan P., additional

Published
2023
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16. Association between thrombus composition and stroke etiology in the MR CLEAN Registry biobank

Author

Hund, Hajo M., Boodt, Nikki, Hansen, Daniel, Haffmans, Willem A., Lycklama à Nijeholt, Geert J., Hofmeijer, Jeannette, Dippel, Diederik W. J., van der Lugt, Aad, van Es, Adriaan C. G. M., van Beusekom, Heleen M. M., Majoie, Charles B. L. M., Roos, Yvo B. W. E. M., van Oostenbrugge, Robert J., van Zwam, Wim H., Boiten, Jelis, Vos, Jan Albert, Jansen, Ivo G. H., Mulder, Maxim J. H. L., Goldhoorn, Robert- Jan B., Compagne, Kars C. J., Kappelhof, Manon, Brouwer, Josje, den Hartog, Sanne J., Hinsenveld, Wouter H., Roozenbeek, Bob, Emmer, Bart J., Coutinho, Jonathan M., Schonewille, Wouter J., Wermer, Marieke J. H., van Walderveen, Marianne A. A., Staals, Julie, Martens, Jasper M., de Bruijn, Sebastiaan F., van Dijk, Lukas C., van der Worp, H. Bart, Lo, Rob H., van Dijk, Ewoud J., Boogaarts, Hieronymus D., de Vries, J., de Kort, Paul L. M., van Tuijl, Julia, Peluso, Jo P., Fransen, Puck, van den Berg, Jan S. P., van Hasselt, Boudewijn A. A. M., Aerden, Leo A. M., Dallinga, René J., Uyttenboogaart, Maarten, Eschgi, Omid, Bokkers, Reinoud P. H., Schreuder, Tobien H. C. M. L., Heijboer, Roel J. J., Keizer, Koos, Yo, Lonneke S. F., den Hertog, Heleen M., Bulut, Tomas, Brouwers, Paul J. A. M., Sprengers, Marieke E. S., Jenniskens, Sjoerd F. M., van den Berg, René, Yoo, Albert J., Beenen, Ludo F. M., Postma, Alida A., Roosendaal, Stefan D., van der Kallen, Bas F. W., van den Wijngaard, Ido R., Bot, Joost, van Doormaal, Pieter-Jan, Meijer, Anton, Ghariq, Elyas, van Proosdij, Marc P., Krietemeijer, G. Menno, Dinkelaar, Wouter, Appelman, Auke P. A., Hammer, Bas, Pegge, Sjoert, van der Hoorn, Anouk, Vinke, Saman, Flach, H. Zwenneke, Lingsma, Hester F., el Ghannouti, Naziha, Sterrenberg, Martin, Pellikaan, Wilma, Sprengers, Rita, Elfrink, Marjan, Simons, Michelle, Vossers, Marjolein, de Meris, Joke, Vermeulen, Tamara, Geerlings, Annet, van Vemde, Gina, Simons, Tiny, Messchendorp, Gert, Nicolaij, Nynke, Bongenaar, Hester, Bodde, Karin, Kleijn, Sandra, Lodico, Jasmijn, Droste, Hanneke, Wollaert, Maureen, Verheesen, Sabrina, Jeurrissen, D., Bos, Erna, Drabbe, Yvonne, Sandiman, Michelle, Aaldering, Nicoline, Zweedijk, Berber, Vervoort, Jocova, Ponjee, Eva, Romviel, Sharon, Kanselaar, Karin, Barning, Denn, Venema, Esmee, Chalos, Vicky, Geuskens, Ralph R., van Straaten, Tim, Ergezen, Saliha, Harmsma, Roger R. M., Muijres, Daan, de Jong, Anouk, Berkhemer, Olvert A., Boers, Anna M. M., Huguet, J., Groot, P. F. C., Mens, Marieke A., van Kranendonk, Katinka R., Treurniet, Kilian M., Tolhuisen, Manon L., Alves, Heitor, Weterings, Annick J., Kirkels, Eleonora L.F., Voogd, Eva J. H. F., Schupp, Lieve M., Collette, Sabine L., Groot, Adrien E. D., LeCouffe, Natalie E., Konduri, Praneeta R., Prasetya, Haryadi, Arrarte-Terreros, Nerea, Ramos, Lucas A., Radiology and Nuclear Medicine, ACS - Microcirculation, ANS - Neurovascular Disorders, Neurology, ACS - Atherosclerosis & ischemic syndromes, ANS - Cellular & Molecular Mechanisms, ANS - Compulsivity, Impulsivity & Attention, Graduate School, Biomedical Engineering and Physics, AMS - Amsterdam Movement Sciences, ANS - Brain Imaging, Adult Psychiatry, APH - Methodology, ​Basic and Translational Research and Imaging Methodology Development in Groningen (BRIDGE), Damage and Repair in Cancer Development and Cancer Treatment (DARE), Cardiology, Radiology & Nuclear Medicine, Radiology and nuclear medicine, Internal medicine, Pediatrics, Amsterdam Neuroscience - Neurovascular Disorders, and CCA - Imaging and biomarkers

Subjects
Microscopy, Ischemic stroke, Radiology, Nuclear Medicine and imaging, Endovascular treatment, Neurology (clinical), Cardiology and Cardiovascular Medicine, Mechanical thrombectomy, Stent-retriever, Thrombus
Abstract

Purpose The composition of thrombi retrieved during endovascular thrombectomy (EVT) in acute ischemic stroke (AIS) due to large vessel occlusion (LVO) may differ depending on their origin. In this study, we investigated the association between thrombus composition and stroke etiology in a large population of patients from the Dutch MR CLEAN Registry treated with EVT in daily clinical practice. Methods The thrombi of 332 patients with AIS were histologically analyzed for red blood cells (RBC), fibrin/platelets (F/P), and white blood cells (leukocytes) using a machine learning algorithm. Stroke etiology was assessed using the Trial of Org 10,172 in acute stroke treatment (TOAST) classification. Results The thrombi of cardioembolic origin contained less RBC and more F/P than those of non-cardioembolic origin (25.8% vs 41.2% RBC [p = 0.003] and 67.1% vs 54.5% F/P [p = 0.004]). The likelihood of a non-cardioembolic source of stroke increased with increasing thrombus RBC content (OR 1.02; [95% CI 1.00–1.06] for each percent increase) and decreased with a higher F/P content (OR 1.02; [95% CI 1.00–1.06]). Thrombus composition in patients with a cardioembolic origin and undetermined origin was similar. Conclusion Thrombus composition is significantly associated with stroke etiology, with an increase in RBC and a decrease in F/P raising the odds for a non-cardioembolic cause. No difference between composition of cardioembolic thrombi and of undetermined origin was seen. This emphasizes the need for more extensive monitoring for arrhythmias and/or extended cardiac analysis in case of an undetermined origin.

Published
2023

20. Validity of Early Outcomes as Indicators for Comparing Hospitals on Quality of Stroke Care

Author

Amini, Marzyeh, primary, Eijkenaar, Frank, additional, Lingsma, Hester F., additional, den Hartog, Sanne J., additional, Olthuis, Susanne G. H., additional, Martens, Jasper, additional, van der Worp, Bart, additional, van Zwam, Wim, additional, van der Hoorn, Anouk, additional, Roosendaal, Stefan D., additional, Roozenbeek, Bob, additional, Dippel, Diederik, additional, van Leeuwen, Nikki, additional, Dippel, Diederik W. J., additional, van der Lugt, Aad, additional, Majoie, Charles B. L. M., additional, Roos, Yvo B. W. E. M., additional, van Oostenbrugge, Robert J., additional, van Zwam, Wim H., additional, Boiten, Jelis, additional, Vos, Jan Albert, additional, Brouwer, Josje, additional, Hinsenveld, Wouter H., additional, Kappelhof, Manon, additional, Compagne, Kars C. J., additional, Goldhoorn, Robert‐Jan B., additional, Mulder, Maxim J. H. L., additional, Jansen, Ivo G. H., additional, van Es, Adriaan C. G. M., additional, Emmer, Bart J., additional, Coutinho, Jonathan M., additional, Schonewille, Wouter J., additional, Wermer, Marieke J. H., additional, van Walderveen, Marianne A. A., additional, Staals, Julie, additional, Hofmeijer, Jeannette, additional, Martens, Jasper M., additional, Lycklama à Nijeholt, Geert J., additional, de Bruijn, Sebastiaan F., additional, van Dijk, Lukas C., additional, van der Worp, H. Bart, additional, Lo, Rob H., additional, van Dijk, Ewoud J., additional, Boogaarts, Hieronymus D., additional, de Vries, J., additional, de Kort, Paul L. M., additional, van Tuijl, Julia, additional, Peluso, Jo Jo P., additional, Fransen, Puck, additional, van den Berg, Jan S. P., additional, van Hasselt, Boudewijn A. A. M., additional, Aerden, Leo A. M., additional, Dallinga, René J., additional, Uyttenboogaart, Maarten, additional, Eschgi, Omid, additional, Bokkers, Reinoud P. H., additional, Schreuder, Tobien H. C. M. L., additional, Heijboer, Roel J. J., additional, Keizer, Koos, additional, Yo, Lonneke S. F., additional, den Hertog, Heleen M., additional, Sturm, Emiel J. C., additional, Brouwers, Paul, additional, Sprengers, Marieke E. S., additional, Jenniskens, Sjoerd F. M., additional, van den Berg, René, additional, Yoo, Albert J., additional, Beenen, Ludo F. M., additional, Postma, Alida A., additional, van der Kallen, Bas F. W., additional, van den Wijngaard, Ido R., additional, Bot, Joost, additional, van Doormaal, Pieter‐Jan, additional, Meijer, Anton, additional, Ghariq, Elyas, additional, van Proosdij, Marc P., additional, Krietemeijer, G. Menno, additional, Peluso, Jo P., additional, Lo, Rob, additional, Dinkelaar, Wouter, additional, Appelman, Auke P. A., additional, Hammer, Bas, additional, Pegge, Sjoert, additional, Vinke, Saman, additional, Flach, H. Zwenneke, additional, el Ghannouti, Naziha, additional, Sterrenberg, Martin, additional, Puppels, Corina, additional, Pellikaan, Wilma, additional, Sprengers, Rita, additional, Elfrink, Marjan, additional, Simons, Michelle, additional, Vossers, Marjolein, additional, de Meris, Joke, additional, Vermeulen, Tamara, additional, Geerlings, Annet, additional, van Vemde, Gina, additional, Simons, Tiny, additional, van Rijswijk, Cathelijn, additional, Messchendorp, Gert, additional, Nicolaij, Nynke, additional, Bongenaar, Hester, additional, Bodde, Karin, additional, Kleijn, Sandra, additional, Lodico, Jasmijn, additional, Droste, Hanneke, additional, Wollaert, Maureen, additional, Verheesen, Sabrina, additional, Jeurrissen, D., additional, Bos, Erna, additional, Drabbe, Yvonne, additional, Sandiman, Michelle, additional, Aaldering, Nicoline, additional, Zweedijk, Berber, additional, Khalilzada, Mostafa, additional, Vervoort, Jocova, additional, Ponjee, Eva, additional, Romviel, Sharon, additional, Kanselaar, Karin, additional, Barning, Denn, additional, Venema, Esmee, additional, Chalos, Vicky, additional, Geuskens, Ralph R., additional, van Straaten, Tim, additional, Ergezen, Saliha, additional, Harmsma, Roger R. M., additional, Muijres, Daan, additional, de Jong, Anouk, additional, Berkhemer, Olvert A., additional, Boers, Anna M. M., additional, Huguet, J., additional, Groot, P. F. C., additional, Mens, Marieke A., additional, van Kranendonk, Katinka R., additional, Treurniet, Kilian M., additional, Tolhuisen, Manon L., additional, Alves, Heitor, additional, Weterings, Annick J., additional, Kirkels, Eleonora L. F., additional, Voogd, Eva J. H. F., additional, Schupp, Lieve M., additional, Collette, Sabine, additional, Groot, Adrien E. D., additional, LeCouffe, Natalie E., additional, Konduri, Praneeta R., additional, Prasetya, Haryadi, additional, Arrarte‐Terreros, Nerea, additional, and Ramos, Lucas A., additional

Published
2023
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22. Workflow Intervals of Endovascular Acute Stroke Therapy During On- Versus Off-Hours: The MR CLEAN Registry

Author

Hinsenveld, Wouter H., de Ridder, Inger R., van Oostenbrugge, Robert J., Vos, Jan A., Groot, Adrien E., Coutinho, Jonathan M., Lycklama à Nijeholt, Geert J., Boiten, Jelis, Schonewille, Wouter J., Dippel, Diederik W.J., van der Lugt, Aad, Majoie, Charles B.L.M., Roos, Yvo B.W.E.M., van Zwam, Wim H., Jansen, Ivo G.H., Mulder, Maxim J.H.L., Goldhoorn, Robert-Jan B., Compagne, Kars C.J., Kappelhof, Manon, Majoie, Charles B.L.M., Wermer, Marieke J.H., van Walderveen, Marianne A.A., Staals, Julie, van Zwam, Wim H., Hofmeijer, Jeannette, Martens, Jasper M., Roozenbeek, Bob, Emmer, Bart J., de Bruijn, Sebastiaan F., van Dijk, Lukas C., van der Worp, H. Bart, Lo, Rob H., van Dijk, Ewoud J., Boogaarts, Hieronymus D., de Kort, Paul L.M., Peluso, Jo J.P., van den Berg, Jan S.P., van Hasselt, Boudewijn A.A.M., Aerden, Leo A.M., Dallinga, René J., Uyttenboogaart, Maarten, Eshghi, Omid, Schreuder, Tobien H.C.M.L., Heijboer, Roel J.J., Keizer, Koos, Yo, Lonneke S.F., den Hertog, Heleen M., Sturm, Emiel J.C., Majoie, Charles B.L.M., van Zwam, Wim H., van der Lugt, Aad, van Walderveen, Marianne A.A., Sprengers, Marieke E.S., Jenniskens, Sjoerd F.M., van den Berg, René, Yoo, Albert J., Beenen, Ludo F.M., Postma, Alida A., Roosendaal, Stefan D., van der Kallen, Bas F.W., van den Wijngaard, Ido R., van Es, Adriaan C.G.M., Emmer, Bart J., Martens, Jasper M., Yo, Lonneke S.F., Bot, Joost, van Doormaal, Pieter-Jan, Dippel, Diederik W.J., van der Lugt, Aad, Majoie, Charles B.L.M., Roos, Yvo B.W.E.M., van Zwam, Wim H., Hofmeijer, Jeannette, Martens, Jasper M., van der Worp, H. Bart, Lo, Rob H., Hofmeijer, Jeannette, Flach, H. Zwenneke, Lingsma, Hester F., el Ghannouti, Naziha, Sterrenberg, Martin, Puppels, Corina, Pellikaan, Wilma, Sprengers, Rita, Elfrink, Marjan, de Meris, Joke, Vermeulen, Tamara, Geerlings, Annet, van Vemde, Gina, Simons, Tiny, van Rijswijk, Cathelijn, Messchendorp, Gert, Bongenaar, Hester, Bodde, Karin, Kleijn, Sandra, Lodico, Jasmijn, Droste, Hanneke, Wollaert, M., Jeurrissen, D., Bos, Ernas, Drabbe, Yvonne, Aaldering, Nicoline, Zweedijk, Berber, Khalilzada, Mostafa, Venema, Esmee, Chalos, Vicky, Geuskens, Ralph R., van Straaten, Tim, Ergezen, Saliha, Harmsma, Roger R.M., Muijres, Daan, de Jong, Anouk, Berkhemer, Olvert A., Boersc, Anna M.M., Huguet, J., Groot, P.F.C., Mens, Marieke A., van Kranendonk, Katinka R., Treurniet, Kilian M., Tolhuijsen, Manon L., and Alves, Heitor

Published
2019
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23. Development of a Core Set of Self-Management Support Needs of Esophageal Cancer Patients: Results from a Delphi Study among Healthcare Professionals

Author

Adriaans, Daniëlle J. M., primary, Heesakkers, Fanny B. M., additional, Teijink, Joep A. W., additional, Dierick-van Daele, Angelique T. M., additional, Haveman, Jan Willem, additional, Sosef, Meindert N., additional, van den Berg, Jan Willem, additional, van Det, Marc J., additional, Hartgrink, Henk H., additional, Jansen, Walther J. B. M., additional, Rosman, Camiel, additional, Lagarde, Sjoerd M., additional, van Esser, Stijn, additional, van der Harst, Erwin, additional, van Laarhoven, Hanneke W. M., additional, and Nieuwenhuijzen, Grard A. P., additional

Published
2023
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25. Additional file 3 of The P2X3 receptor antagonist filapixant in patients with refractory chronic cough: a randomized controlled trial

Author

Friedrich, Christian, Francke, Klaus, Birring, Surinder S., van den Berg, Jan Willem K., Marsden, Paul A., McGarvey, Lorcan, Turner, Alice M., Wielders, Pascal, Gashaw, Isabella, Klein, Stefan, and Morice, Alyn H.

Abstract

Additional file 3: Table S1. 24-h cough monitoring: Cough count [1/hour]. Table S2. 24-h cough frequency: Subgroup analyses by baseline cough count (Bayesian mixed model). Table S3. 24-h cough frequency: Responder rates for different change thresholds. Table S4. VAS cough severity: Responder rates. Table S5. Treatment-emergent adverse events observed in > 5% of patients. Table S6. Cough frequency: Subgroup analyses by occurrence of taste-related adverse events (Bayesian mixed model). Table S7. Cough severity (VAS): Subgroup analyses by occurrence of taste-related adverse events (Bayesian mixed model). Figure S1. Plasma concentration–time curves for filapixant after multiple administrations.

Published
2023
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30. Determinants of Symptomatic Intracranial Hemorrhage After Endovascular Stroke Treatment: A Retrospective Cohort Study

Author

van der Steen, Wouter, primary, van der Ende, Nadinda A.M., additional, van Kranendonk, Katinka R., additional, Chalos, Vicky, additional, van Oostenbrugge, Robert J., additional, van Zwam, Wim H., additional, Roos, Yvo B.W.E.M., additional, van Doormaal, Pieter J., additional, van Es, Adriaan C.G.M., additional, Lingsma, Hester F., additional, Majoie, Charles B.L.M., additional, van der Lugt, Aad, additional, Dippel, Diederik W.J., additional, Roozenbeek, Bob, additional, Boiten, Jelis, additional, Albert Vos, Jan, additional, Jansen, Ivo G.H., additional, Mulder, Maxim J.H.L., additional, Goldhoorn, Robert- Jan B., additional, Compagne, Kars C.J., additional, Kappelhof, Manon, additional, Brouwer, Josje, additional, den Hartog, Sanne J., additional, Emmer, Bart J., additional, Coutinho, Jonathan M., additional, Schonewille, Wouter J., additional, Wermer, Marieke J.H., additional, van Walderveen, Marianne A.A., additional, Staals, Julie, additional, Hofmeijer, Jeannette, additional, Martens, Jasper M., additional, Lycklama à Nijeholt, Geert J., additional, de Bruijn, Sebastiaan F., additional, van Dijk, Lukas C., additional, van der Worp, H. Bart, additional, Lo, Rob H., additional, van Dijk, Ewoud J., additional, Boogaarts, Hieronymus D., additional, de Vries, J., additional, de Kort, Paul L.M., additional, van Tuijl, Julia, additional, Peluso, Jo P., additional, Fransen, Puck, additional, van den Berg, Jan S.P., additional, van Hasselt, Boudewijn A.A.M., additional, Aerden, Leo A.M., additional, Dallinga, René J., additional, Uyttenboogaart, Maarten, additional, Eschgi, Omid, additional, Bokkers, Reinoud P.H., additional, Schreuder, Tobien H.C.M.L., additional, Heijboer, Roel J.J., additional, Keizer, Koos, additional, Yo, Lonneke S.F., additional, den Hertog, Heleen M., additional, Bulut, Tomas, additional, Brouwers, Paul J.A.M., additional, Lycklama, Geert J., additional, Sprengers, Marieke E.S., additional, Jenniskens, Sjoerd F.M., additional, van den Berg, René, additional, Yoo, Albert J., additional, Beenen, Ludo F.M., additional, Postma, Alida A., additional, Roosendaal, Stefan D., additional, van der Kallen, Bas F.W., additional, van den Wijngaard, Ido R., additional, Vos, Jan Albert, additional, Bot, Joost, additional, Meijer, Anton, additional, Ghariq, Elyas, additional, van Proosdij, Marc P., additional, Krietemeijer, G. Menno, additional, Lo, Rob, additional, Dinkelaar, Wouter, additional, Auke, P.A., additional, Hammer, Bas, additional, Pegge, Sjoert, additional, van der Hoorn, Anouk, additional, Vinke, Saman, additional, Flach, H. Zwenneke, additional, el Ghannouti, Naziha, additional, Sterrenberg, Martin, additional, Pellikaan, Wilma, additional, Sprengers, Rita, additional, Elfrink, Marjan, additional, Simons, Michelle, additional, Vossers, Marjolein, additional, de Meris, Joke, additional, Vermeulen, Tamara, additional, Geerlings, Annet, additional, van Vemde, Gina, additional, Simons, Tiny, additional, Messchendorp, Gert, additional, Nicolaij, Nynke, additional, Bongenaar, Hester, additional, Bodde, Karin, additional, Kleijn, Sandra, additional, Lodico, Jasmijn, additional, Droste, Hanneke, additional, Wollaert, Maureen, additional, Verheesen, Sabrina, additional, Jeurrissen, D., additional, Bos, Erna, additional, Drabbe, Yvonne, additional, Sandiman, Michelle, additional, Aaldering, Nicoline, additional, Zweedijk, Berber, additional, Vervoort, Jocova, additional, Ponjee, Eva, additional, Romviel, Sharon, additional, Kanselaar, Karin, additional, Barning, Denn, additional, Venema, Esmee, additional, Geuskens, Ralph R., additional, van Straaten, Tim, additional, Ergezen, Saliha, additional, Harmsma, Roger R.M., additional, Muijres, Daan, additional, de Jong, Anouk, additional, Berkhemer, Olvert A., additional, Boers, Anna M.M., additional, Huguet, J., additional, Groot, P.F.C., additional, Mens, Marieke A., additional, Treurniet, Kilian M., additional, Tolhuisen, Manon L., additional, Alves, Heitor, additional, Weterings, Annick J., additional, Kirkels, Eleonora L.F., additional, Voogd, Eva J.H.F., additional, Schupp, Lieve M., additional, Collette, Sabine L., additional, Groot, Adrien E.D., additional, LeCouffe, Natalie E., additional, Konduri, Praneeta R., additional, Prasetya, Haryadi, additional, Arrarte- Terreros, Nerea, additional, Ramos, Lucas A., additional, Brown, Martin M., additional, Liebig, Thomas, additional, van der Heijden, Esther, additional, Ghannouti, Naziha, additional, Fleitour, Nadine, additional, Hooijenga, Imke, additional, Puppels, Corina, additional, Geerling, Annet, additional, Lindl-Velema, Annemieke, additional, de Ridder, Ans, additional, Greebe, Paut, additional, de Bont- Stikkelbroeck, Jose, additional, Haaglanden, MC, additional, Janssen, Kirsten, additional, Licher, Silvan, additional, Boodt, Nikki, additional, Ros, Adriaan, additional, Slokkers, Ilse, additional, Ganpat, Raymie-Jayce, additional, Mulder, Maxim, additional, Saiedie, Nawid, additional, Heshmatollah, Alis, additional, Schipperen, Stefanie, additional, Vinken, Stefan, additional, van Boxtel, Tiemen, additional, Koets, Jeroen, additional, Boers, Merel, additional, Santos, Emilie, additional, Borst, Jordi, additional, Jansen, Ivo, additional, Lucas, Marit, additional, Geuskens, Ralph Renan, additional, and Sales Barros, Roeland, additional

Published
2022
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32. Etiology of Large Vessel Occlusion Posterior Circulation Stroke: Results of the MR CLEAN Registry

Author

Pirson, F.A.V. (Anne), primary, Boodt, Nikki, additional, Brouwer, Josje, additional, Bruggeman, Agnetha A.E., additional, Hinsenveld, Wouter H., additional, Staals, Julie, additional, van Zwam, Wim H., additional, van der Leij, Christiaan, additional, Brans, Rutger J.B., additional, Majoie, Charles B.L.M., additional, Dippel, Diederik W.J., additional, van der Lugt, Aad, additional, Schonewille, Wouter J., additional, van Oostenbrugge, Robert J., additional, Roos, Yvo B.W.E.M., additional, Boiten, Jelis, additional, Albert Vos, Jan, additional, Jansen, Ivo G.H., additional, Mulder, Maxim J.H.L., additional, Goldhoorn, Robert- Jan B., additional, Compagne, Kars C.J., additional, Kappelhof, Manon, additional, den Hartog, Sanne J., additional, Roozenbeek, Bob, additional, Emmer, Bart J., additional, Coutinho, Jonathan M., additional, Vos, Jan Albert, additional, Wermer, Marieke J.H., additional, van Walderveen, Marianne A.A., additional, van Es, Adriaan C.G.M., additional, Hofmeijer, Jeannette, additional, Martens, Jasper M., additional, Lycklama à Nijeholt, Geert J., additional, de Bruijn, Sebastiaan F., additional, van Dijk, Lukas C., additional, Bart van der Worp, H., additional, Lo, Rob H., additional, van Dijk, Ewoud J., additional, Boogaarts, Hieronymus D., additional, de Vries, J., additional, de Kort, Paul L.M., additional, van Tuijl, Julia, additional, Peluso, Jo P., additional, Fransen, Puck, additional, van den Berg, Jan S.P., additional, van Hasselt, Boudewijn A.A.M., additional, Aerden, Leo A.M., additional, Dallinga, René J., additional, Uyttenboogaart, Maarten, additional, Eschgi, Omid, additional, Bokkers, Reinoud P.H., additional, Schreuder, Tobien H.C.M.L., additional, Heijboer, Roel J.J., additional, Keizer, Koos, additional, Yo, Lonneke S.F., additional, den Hertog, Heleen M., additional, Sturm, Emiel J.C., additional, Brouwers, Paul J.A.M., additional, Sprengers, Marieke E.S., additional, Jenniskens, Sjoerd F.M., additional, van den Berg, René, additional, Yoo, Albert J., additional, Beenen, Ludo F.M., additional, Postma, Alida A., additional, Roosendaal, Stefan D., additional, van der Kallen, Bas F.W., additional, van den Wijngaard, Ido R., additional, Bot, Joost, additional, van Doormaal, Pieter-Jan, additional, Meijer, Anton, additional, Ghariq, Elyas, additional, van Proosdij, Marc P., additional, Menno Krietemeijer, G., additional, Lo, Rob, additional, Gerrits, Dick, additional, Dinkelaar, Wouter, additional, Appelman, Auke P.A., additional, Hammer, Bas, additional, Pegge, Sjoert, additional, van der Hoorn, Anouk, additional, Vinke, Saman, additional, Cornelissen, Sandra, additional, Brans, Rutger, additional, Zwenneke Flach, H., additional, Lingsma, Hester F., additional, Ghannouti, Naziha el, additional, Sterrenberg, Martin, additional, Pellikaan, Wilma, additional, Sprengers, Rita, additional, Elfrink, Marjan, additional, Simons, Michelle, additional, Vossers, Marjolein, additional, de Meris, Joke, additional, Vermeulen, Tamara, additional, Geerlings, Annet, additional, van Vemde, Gina, additional, Simons, Tiny, additional, Messchendorp, Gert, additional, Nicolaij, Nynke, additional, Bongenaar, Hester, additional, Bodde, Karin, additional, Kleijn, Sandra, additional, Lodico, Jasmijn, additional, Droste, Hanneke, additional, Wollaert, Maureen, additional, Verheesen, Sabrina, additional, Jeurrissen, D., additional, Bos, Erna, additional, Drabbe, Yvonne, additional, Sandiman, Michelle, additional, Aaldering, Nicoline, additional, Zweedijk, Berber, additional, Vervoort, Jocova, additional, Ponjee, Eva, additional, Romviel, Sharon, additional, Kanselaar, Karin, additional, Barning, Denn, additional, Venema, Esmee, additional, Chalos, Vicky, additional, Geuskens, Ralph R., additional, van Straaten, Tim, additional, Ergezen, Saliha, additional, Harmsma, Roger R.M., additional, Muijres, Daan, additional, de Jong, Anouk, additional, Berkhemer, Olvert A., additional, Boers, Anna M.M., additional, Huguet, J., additional, Groot, P.F.C., additional, Mens, Marieke A., additional, van Kranendonk, Katinka R., additional, Treurniet, Kilian M., additional, Tolhuisen, Manon L., additional, Alves, Heitor, additional, Weterings, Annick J., additional, Kirkels, Eleonora L.F., additional, Voogd, Eva J.H.F., additional, Schupp, Lieve M., additional, Collette, Sabine L., additional, Groot, Adrien E.D., additional, LeCouffe, Natalie E., additional, Konduri, Praneeta R., additional, Prasetya, Haryadi, additional, Arrarte-Terreros, Nerea, additional, Ramos, Lucas A., additional, and Pirson, Anne F.A.V., additional

Published
2022
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35. Time to Endovascular Treatment and Outcome in Acute Ischemic Stroke: MR CLEAN Registry Results

Author

Mulder, Maxim J.H.L., Jansen, Ivo G.H., Goldhoorn, Robert-Jan B., Venema, Esmee, Chalos, Vicky, Compagne, Kars C.J., Roozenbeek, Bob, Lingsma, Hester F., Schonewille, Wouter J., van den Wijngaard, Ido R., Boiten, Jelis, Albert Vos, Jan, Roos, Yvo B.W.EM., van Oostenbrugge, Robert J., van Zwam, Wim H., Majoie, Charles B.L.M., van der Lugt, Aad, Dippel, Diederik W.J., Vos, Jan Albert, Coutinho, Jonathan, Wermer, Marieke J.H., van Walderveen, Marianne A.A., Staals, Julie, Hofmeijer, Jeannette, Martens, Jasper, Lycklamà Nijeholt, Geert J., Emmer, Bart J., de Bruijn, Sebastiaan F., van Dijk, Lukas C., van der Worp, H. Bart, Lo, Rob H., van Dijk, Ewoud J., Boogaarts, Jeroen, de Kort, Paul L.M., Peluso, Jo, van den Berg, Jan S.P., van Hasselt, Boudewijn A.A.M., Aerden, Leo A.M., Dallinga, René J., Uyttenboogaart, Maarten, Eshghi, Omid, Schreuder, Tobien H.C.M.L., Heijboer, Roel J.J., Keizer, Koos, Yo, Lonneke, den Hertog, Heleen M., Sturm, Emiel J.C., Sprengers, Marieke E.S., Jenniskens, Sjoerd F.M., van den Berg, René, Yoo, Albert J., Beenen, Ludo F.M., Roosendaal, Stefan, van der Kallen, Bas, van den Wijngaard, Ido, van Es, Ad, Emmer, Bart, Bot, Joost, van Doormaal, Pieter-Jan, Martens, Jasper M., Flach, H. Zwenneke, Ghannouti, Naziha el, Sterrenberg, Martin, Puppels, Corina, Pellikaan, Wilma, Sprengers, Rita, Elfrink, Marjan, de Meris, Joke, Vermeulen, Tamara, Geerlings, Annet, van Vemde, Gina, Simons, Tiny, van Rijswijk, Cathelijn, Messchendorp, Gert, Bongenaar, Hester, Bodde, Karin, Kleijn, Sandra, Lodico, Jasmijn, Droste, Hanneke, Wollaert, Maureen, Ramakers, Daisy, Bos, Ernas, Drabbe, Yvonne, Zweedijk, Berber, Khalilzada, Mostafa, Geuskens, Ralph R., van Straaten, Tim, Ergezen, Saliha, Harmsma, Roger R.M., Muijres, Daan, de Jong, Anouk, Hinsenveld, Wouter, Berkhemer, Olvert A., Boers, Anna M.M., Huguet, J., Groot, P.F.C., Mens, Marieke A., van Kranendonk, Katinka R., Treurniet, Kilian M., Kappelhof, Manon, Tolhuijsen, Manon L., and Alves, Heitor

Published
2018
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36. Improvements in Endovascular Treatment for Acute Ischemic Stroke: A Longitudinal Study in the MR CLEAN Registry

Author

Compagne, Kars C.J., primary, Kappelhof, Manon, additional, Hinsenveld, Wouter H., additional, Brouwer, Josje, additional, Goldhoorn, Robert-Jan B., additional, Uyttenboogaart, Maarten, additional, Bokkers, Reinoud P.H., additional, Schonewille, Wouter J., additional, Martens, Jasper M., additional, Hofmeijer, Jeannette, additional, van der Worp, H. Bart, additional, Lo, Rob T.H., additional, Keizer, Koos, additional, Yo, Lonneke S.F., additional, Lycklama à Nijeholt, Geert J., additional, den Hertog, Heleen M., additional, Sturm, Emiel J.C., additional, Brouwers, Paul J.A.M., additional, van Walderveen, Marianne A.A., additional, Wermer, Marieke J.H., additional, de Bruijn, Sebastiaan F., additional, van Dijk, Lukas C., additional, Boogaarts, Hieronymus D., additional, van Dijk, Ewout J., additional, van Tuijl, Julia H., additional, Peluso, Jo P.P., additional, de Kort, Paul L.M., additional, van Hasselt, Boudewijn A.A.M., additional, Fransen, Puck S., additional, Schreuder, Tobien H.C.M.L., additional, Heijboer, Roel J.J., additional, Jenniskens, Sjoerd F.M., additional, Sprengers, Marieke E.S., additional, Ghariq, Elias, additional, van den Wijngaard, Ido R., additional, Roosendaal, Stefan D., additional, Meijer, Anton F.J.A., additional, Beenen, Ludo F.M., additional, Postma, Alida A., additional, van den Berg, René, additional, Yoo, Albert J., additional, van Doormaal, Pieter Jan, additional, van Proosdij, Marc P., additional, Krietemeijer, Menno G.M., additional, Gerrits, Dick G., additional, Hammer, Sebastiaan, additional, Vos, Jan Albert, additional, Boiten, Jelis, additional, Coutinho, Jonathan M., additional, Emmer, Bart J., additional, van Es, Ad C.G.M., additional, Roozenbeek, Bob, additional, Roos, Yvo B.W.E.M., additional, van Zwam, Wim H., additional, van Oostenbrugge, Robert J., additional, Majoie, Charles B.L.M., additional, Dippel, Diederik W.J., additional, van der Lugt, Aad, additional, Jansen, Ivo G.H., additional, Mulder, Maxim J.H.L., additional, den Hartog, Sanne J., additional, Albert Vos, Jan, additional, Staals, Julie, additional, Lo, Rob H., additional, van Dijk, Ewoud J., additional, de Vries, J., additional, van Tuijl, Julia, additional, Peluso, Jo P., additional, Fransen, Puck, additional, van den Berg, Jan S.P., additional, Aerden, Leo A.M., additional, Dallinga, René J., additional, Eschgi, Omid, additional, Bulut, Tomas, additional, van der Kallen, Bas F.W., additional, Bot, Joost, additional, van Doormaal, Pieter-Jan, additional, Meijer, Anton, additional, Ghariq, Elyas, additional, Lo, Rob, additional, Dinkelaar, Wouter, additional, Appelman, Auke P.A., additional, Hammer, Bas, additional, Pegge, Sjoert, additional, van der Hoorn, Anouk, additional, Vinke, Saman, additional, Flach, H. Zwenneke, additional, Lingsma, Hester F., additional, el Ghannouti, Naziha, additional, Sterrenberg, Martin, additional, Pellikaan, Wilma, additional, Sprengers, Rita, additional, Elfrink, Marjan, additional, Simons, Michelle, additional, Vossers, Marjolein, additional, de Meris, Joke, additional, Vermeulen, Tamara, additional, Geerlings, Annet, additional, van Vemde, Gina, additional, Simons, Tiny, additional, Messchendorp, Gert, additional, Nicolaij, Nynke, additional, Bongenaar, Hester, additional, Bodde, Karin, additional, Kleijn, Sandra, additional, Lodico, Jasmijn, additional, Droste, Hanneke, additional, Wollaert, Maureen, additional, Verheesen, Sabrina, additional, Jeurrissen, D., additional, Bos, Erna, additional, Drabbe, Yvonne, additional, Sandiman, Michelle, additional, Aaldering, Nicoline, additional, Zweedijk, Berber, additional, Vervoort, Jocova, additional, Ponjee, Eva, additional, Romviel, Sharon, additional, Kanselaar, Karin, additional, Barning, Denn, additional, Venema, Esmee, additional, Chalos, Vicky, additional, Geuskens, Ralph R., additional, van Straaten, Tim, additional, Ergezen, Saliha, additional, Harmsma, Roger R.M., additional, Muijres, Daan, additional, de Jong, Anouk, additional, Berkhemer, Olvert A., additional, Boers, Anna M.M., additional, Huguet, J., additional, Groot, P.F.C., additional, Mens, Marieke A., additional, van Kranendonk, Katinka R., additional, Treurniet, Kilian M., additional, Tolhuisen, Manon L., additional, Alves, Heitor, additional, Weterings, Annick J., additional, Kirkels, Eleonora L.F., additional, Voogd, Eva J.H.F., additional, Schupp, Lieve M., additional, Collette, Sabine L., additional, Groot, Adrien E.D., additional, LeCouffe, Natalie E., additional, Konduri, Praneeta R., additional, Prasetya, Haryadi, additional, Arrarte-Terreros, Nerea, additional, and Ramos, Lucas A., additional

Published
2022
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39. Clot Burden Score on Baseline Computerized Tomographic Angiography and Intra-Arterial Treatment Effect in Acute Ischemic Stroke

Author

Treurniet, Kilian M., Yoo, Albert J., Berkhemer, Olvert A., Lingsma, Hester F., Boers, Anna M.M., Fransen, Puck S.S., Beumer, Debbie, van den Berg, Lucie A., Sprengers, Marieke E.S., Jenniskens, Sjoerd F.M., Lycklama À Nijeholt, Geert J., van Walderveen, Marianne A.A., Bot, Joseph C.J., Beenen, Ludo F.M., van den Berg, René, van Zwam, Wim H., van der Lugt, Aad, van Oostenbrugge, Robert J., Dippel, Diederik W.J., Roos, Yvo B.W.E.M., Marquering, Henk A., Majoie, Charles B.L.M., Schonewille, Wouter J., Albert Vos, Jan, Nederkoorn, Paul J., Wermer, Marieke J.H., Staals, Julie, Hofmeijer, Jeannette, van Oostayen, Jacques A., Boiten, Jelis, Brouwer, Patrick A., Emmer, Bart J., de Bruijn, Sebastiaan F., van Dijk, Lukas C., Kappelle, L. Jaap, Lo, Rob H., van Dijk, Ewoud J., de Vries, Joost, de Kort, Paul L.M., van den Berg, Jan S.P., van Rooij, Willem Jan J., van Hasselt, Boudewijn A.A.M., Aerden, Leo A.M., Dallinga, René J., Visser, Marieke C., Vroomen, Patrick C., Eshghi, Omid, Schreuder, Tobien H.C.M.L., Heijboer, Roel J.J., Keizer, Koos, Tielbeek, Alexander V., den Hertog, Heleen M., Gerrits, Dick G., van den Berg-Vos, Renske M., Karas, Giorgos B., Koudstaal, Peter J., Boiten, Jelis, van Dijk, Ewoud J., Wermer, Marieke J.H., Flach, H. Zwenneke, and Steyerberg, Ewout W

Published
2016
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42. Economic Evaluation of Endovascular Treatment for Acute Ischemic Stroke

Author

van den Berg, Lucie A., primary, Berkhemer, Olvert A., additional, Fransen, Puck S.S., additional, Beumer, Debbie, additional, Lingsma, Hester, additional, Majoie, Charles B.M., additional, Dippel, Diederik W.J., additional, van der Lugt, Aad, additional, van Oostenbrugge, Robert J., additional, van Zwam, Wim H., additional, Roos, Yvo B., additional, Dijkgraaf, Marcel G.W., additional, Yoo, Albert J., additional, Schonewille, Wouter J., additional, Vos, Jan Albert, additional, Nederkoorn, Paul J., additional, Wermer, Marieke J.H., additional, van Walderveen, Marianne A.A., additional, Staals, Julie, additional, Hofmeijer, Jeannette, additional, van Oostayen, Jacques A., additional, Lycklama à Nijeholt, Geert J., additional, Boiten, Jelis, additional, Brouwer, Patrick A., additional, Emmer, Bart J., additional, de Bruijn, Sebastiaan F., additional, van Dijk, Lukas C., additional, Kappelle, L. Jaap, additional, Lo, Rob H., additional, van Dijk, Ewoud J., additional, de Vries, Joost, additional, de Kort, Paul L.M., additional, van den Berg, Jan S.P., additional, van Hasselt, Boudewijn A.A.M., additional, Aerden, Leo A.M., additional, Dallinga, René J., additional, Visser, Marieke C., additional, Bot, Joseph C.J., additional, Vroomen, Patrick C., additional, Eshghi, Omid, additional, Schreuder, Tobien H.C.M.L., additional, Heijboer, Roel J.J., additional, Keizer, Koos, additional, Tielbeek, Alexander V., additional, den Hertog, Heleen M., additional, Gerrits, Dick G., additional, van den Berg-Vos, Renske M., additional, Karas, Giorgos B., additional, Steyerberg, Ewout W., additional, Flach, H. Zwenneke, additional, Marquering, Henk A., additional, Sprengers, Marieke E.S., additional, Jenniskens, Sjoerd F.M., additional, Beenen, Ludo F.M., additional, van den Berg, René, additional, and Koudstaal, Peter J., additional

Published
2022
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43. Endovascular Treatment for Posterior Circulation Stroke in Routine Clinical Practice: Results of the Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands Registry

Author

Pirson, F. Anne V., primary, Boodt, Nikki, additional, Brouwer, Josje, additional, Bruggeman, Agnetha A.E., additional, den Hartog, Sanne J., additional, Goldhoorn, Robert-Jan B., additional, Langezaal, Lucianne C.M., additional, Staals, Julie, additional, van Zwam, Wim H., additional, van der Leij, Christiaan, additional, Brans, Rutger J.B., additional, Majoie, Charles B.L.M., additional, Coutinho, Jonathan M., additional, Emmer, Bart J., additional, Dippel, Diederik W.J., additional, van der Lugt, Aad, additional, Vos, Jan-Albert, additional, van Oostenbrugge, Robert J., additional, Schonewille, Wouter J., additional, Roos, Yvo B.W.E.M., additional, Boiten, Jelis, additional, Vos, Jan Albert, additional, Jansen, Ivo G.H., additional, Mulder, Maxim J.H.L., additional, Compagne, Kars C.J., additional, Kappelhof, Manon, additional, Hinsenveld, Wouter H., additional, Roozenbeek, Bob, additional, Wermer, Marieke J.H., additional, van Walderveen, Marianne A.A., additional, van Es, Adriaan C.G.M., additional, Hofmeijer, Jeannette, additional, Martens, Jasper M., additional, Lycklama à Nijeholt, Geert J., additional, de Bruijn, Sebastiaan F., additional, van Dijk, Lukas C., additional, van der Worp, H. Bart, additional, Lo, Rob H., additional, van Dijk, Ewoud J., additional, Boogaarts, Hieronymus D., additional, de Vries, J., additional, de Kort, Paul L.M., additional, van Tuijl, Julia, additional, Peluso, Jo P., additional, Fransen, Puck, additional, van den Berg, Jan S.P., additional, van Hasselt, Boudewijn A.A.M., additional, Aerden, Leo A.M., additional, Dallinga, René J., additional, Uyttenboogaart, Maarten, additional, Eschgi, Omid, additional, Bokkers, Reinoud P.H., additional, Schreuder, Tobien H.C.M.L., additional, Heijboer, Roel J.J., additional, Keizer, Koos, additional, Yo, Lonneke S.F., additional, den Hertog, Heleen M., additional, Sturm, Emiel J.C., additional, Brouwers, Paul J.A.M., additional, Sprengers, Marieke E.S., additional, Jenniskens, Sjoerd F.M., additional, van den Berg, René, additional, Yoo, Albert J., additional, Beenen, Ludo F.M., additional, Postma, Alida A., additional, Roosendaal, Stefan D., additional, van der Kallen, Bas F.W., additional, van den Wijngaard, Ido R., additional, Bot, Joost, additional, van Doormaal, Pieter-Jan, additional, Meijer, Anton, additional, Ghariq, Elyas, additional, van Proosdij, Marc P., additional, Menno Krietemeijer, G., additional, Lo, Rob, additional, Gerrits, Dick, additional, Dinkelaar, Wouter, additional, Appelman, Auke P.A., additional, Hammer, Bas, additional, Pegge, Sjoert, additional, van der Hoorn, Anouk, additional, Vinke, Saman, additional, Cornelissen, Sandra, additional, à Nijeholt, Geert J. Lycklama, additional, Flach, H. Zwenneke, additional, Lingsma, Hester F., additional, Ghannouti, Naziha el, additional, Sterrenberg, Martin, additional, Pellikaan, Wilma, additional, Sprengers, Rita, additional, Elfrink, Marjan, additional, Simons, Michelle, additional, Vossers, Marjolein, additional, de Meris, Joke, additional, Vermeulen, Tamara, additional, Geerlings, Annet, additional, van Vemde, Gina, additional, Simons, Tiny, additional, Messchendorp, Gert, additional, Nicolaij, Nynke, additional, Bongenaar, Hester, additional, Bodde, Karin, additional, Kleijn, Sandra, additional, Lodico, Jasmijn, additional, Droste, Hanneke, additional, Wollaert, Maureen, additional, Verheesen, Sabrina, additional, Jeurrissen, D., additional, Bos, Erna, additional, Drabbe, Yvonne, additional, Sandiman, Michelle, additional, Aaldering, Nicoline, additional, Zweedijk, Berber, additional, Vervoort, Jocova, additional, Ponjee, Eva, additional, Romviel, Sharon, additional, Kanselaar, Karin, additional, Barning, Denn, additional, Venema, Esmee, additional, Chalos, Vicky, additional, Geuskens, Ralph R., additional, van Straaten, Tim, additional, Ergezen, Saliha, additional, Harmsma, Roger R.M., additional, Muijres, Daan, additional, de Jong, Anouk, additional, Berkhemer, Olvert A., additional, Boers, Anna M.M., additional, Huguet, J., additional, Groot, P.F.C., additional, Mens, Marieke A., additional, van Kranendonk, Katinka R., additional, Treurniet, Kilian M., additional, Tolhuisen, Manon L., additional, Alves, Heitor, additional, Weterings, Annick J., additional, Kirkels, Eleonora L.F., additional, Voogd, Eva J.H.F., additional, Schupp, Lieve M., additional, Collette, Sabine L., additional, Groot, Adrien E.D., additional, LeCouffe, Natalie E., additional, Konduri, Praneeta R., additional, Prasetya, Haryadi, additional, Arrarte-Terreros, Nerea, additional, and Ramos, Lucas A., additional

Published
2022
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44. Added Value of a Blinded Outcome Adjudication Committee in an Open-Label Randomized Stroke Trial

Author

van der Ende, Nadinda A.M., primary, Roozenbeek, Bob, additional, Berkhemer, Olvert A., additional, Koudstaal, Peter J., additional, Boiten, Jelis, additional, van Dijk, Ewoud J., additional, Roos, Yvo B.W.E.M., additional, van Oostenbrugge, Robert J., additional, Majoie, Charles B.L.M., additional, van Zwam, Wim, additional, Lingsma, Hester F., additional, van der Lugt, Aad, additional, Dippel, Diederik W.J., additional, Fransen, Puck S.S., additional, Beumer, Debbie, additional, van den Berg, Lucie A., additional, Yoo, Albert J., additional, Schonewille, Wouter J., additional, Vos, Jan Albert, additional, Nederkoorn, Paul J., additional, Wermer, Marieke J.H., additional, van Walderveen, Marianne A.A., additional, Staals, Julie, additional, Hofmeijer, Jeannette, additional, van Oostayen, Jacques A., additional, Lycklama a Nijeholt, Geert J., additional, Brouwer, Patrick A., additional, Emmer, Bart J., additional, de Bruijn, Sebastiaan F., additional, van Dijk, Lukas C., additional, Kappelle, L. Jaap, additional, Lo, Rob H., additional, de Vries, Joost, additional, de Kort, Paul L.M., additional, van Rooij, Willem Jan J., additional, van den Berg, Jan S.P., additional, van Hasselt, Boudewijn A.A.M., additional, Aerden, Leo A.M., additional, Dallinga, Rene J., additional, Visser, Marieke C., additional, Bot, Joseph C.J., additional, Vroomen, Patrick C., additional, Eshghi, Omid, additional, Schreuder, Tobien H.C.M.L., additional, Heijboer, Roel J.J., additional, Keizer, Koos, additional, Tielbeek, Alexander V., additional, den Hertog, Heleen M., additional, Gerrits, Dick G., additional, van den Berg-Vos, Renske M., additional, Karas, Giorgos B., additional, Steyerberg, Ewout W., additional, Flach, H. Zwenneke, additional, Marquering, Henk A., additional, Sprengers, Marieke E.S., additional, Jenniskens, Sjoerd F.M., additional, Beenen, Ludo F.M., additional, and van den Berg, Rene, additional

Published
2022
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48. Hospital Variation in Time to Endovascular Treatment for Ischemic Stroke: What Is the Optimal Target for Improvement?

Author

den Hartog, Sanne J., primary, Lingsma, Hester F., additional, van Doormaal, Pieter‐Jan, additional, Hofmeijer, Jeannette, additional, Yo, Lonneke S. F., additional, Majoie, Charles B. L. M., additional, Dippel, Diederik W. J., additional, van der Lugt, Aad, additional, Roozenbeek, Bob, additional, Roos, Yvo B. W. E. M., additional, van Oostenbrugge, Robert J., additional, van Zwam, Wim H., additional, Boiten, Jelis, additional, Vos, Jan Albert, additional, Jansen, Ivo G. H., additional, Mulder, Maxim J. H. L., additional, Goldhoorn, Robert‐ Jan B., additional, Compagne, Kars C. J., additional, Kappelhof, Manon, additional, Brouwer, Josje, additional, den Hartog, Sanne J., additional, Hinsenveld, Wouter H., additional, van Es, Adriaan C. G. M., additional, Emmer, Bart J., additional, Coutinho, Jonathan M., additional, Schonewille, Wouter J., additional, Wermer, Marieke J. H., additional, van Walderveen, Marianne A. A., additional, Staals, Julie, additional, Martens, Jasper M., additional, Lycklama à Nijeholt, Geert J., additional, de Bruijn, Sebastiaan F., additional, van Dijk, Lukas C., additional, van der Worp, H. Bart, additional, Lo, Rob H., additional, van Dijk, Ewoud J., additional, Boogaarts, Hieronymus D., additional, de Vries, J., additional, de Kort, Paul L. M., additional, van Tuijl, Julia, additional, Peluso, Jo P., additional, Fransen, Puck, additional, van den Berg, Jan S. P., additional, van Hasselt, Boudewijn A. A. M., additional, Aerden, Leo A. M., additional, Dallinga, René J., additional, Uyttenboogaart, Maarten, additional, Eschgi, Omid, additional, Bokkers, Reinoud P. H., additional, Schreuder, Tobien H. C. M. L., additional, Heijboer, Roel J. J., additional, Keizer, Koos, additional, den Hertog, Heleen M., additional, Sturm, Emiel J. C., additional, Brouwers, Paul J. A. M., additional, Sprengers, Marieke E. S., additional, Jenniskens, Sjoerd F. M., additional, van den Berg, René, additional, Yoo, Albert J., additional, Beenen, Ludo F. M., additional, Postma, Alida A., additional, Roosendaal, Stefan D., additional, van der Kallen, Bas F. W., additional, van den Wijngaard, Ido R., additional, Bot, Joost, additional, Meijer, Anton, additional, Ghariq, Elyas, additional, van Proosdij, Marc P., additional, Menno Krietemeijer, G., additional, Gerrits, Dick, additional, Dinkelaar, Wouter, additional, Appelman, Auke P. A., additional, Hammer, Bas, additional, Pegge, Sjoert, additional, van der Hoorn, Anouk, additional, Vinke, Saman, additional, Zwenneke Flach, H, additional, Ghannouti, Naziha el, additional, Sterrenberg, Martin, additional, Pellikaan, Wilma, additional, Sprengers, Rita, additional, Elfrink, Marjan, additional, Simons, Michelle, additional, Vossers, Marjolein, additional, de Meris, Joke, additional, Vermeulen, Tamara, additional, Geerlings, Annet, additional, van Vemde, Gina, additional, Simons, Tiny, additional, Messchendorp, Gert, additional, Nicolaij, Nynke, additional, Bongenaar, Hester, additional, Bodde, Karin, additional, Kleijn, Sandra, additional, Lodico, Jasmijn, additional, Droste, Hanneke, additional, Wollaert, Maureen, additional, Verheesen, Sabrina, additional, Jeurrissen, D., additional, Bos, Erna, additional, Drabbe, Yvonne, additional, Sandiman, Michelle, additional, Aaldering, Nicoline, additional, Zweedijk, Berber, additional, Vervoort, Jocova, additional, Ponjee, Eva, additional, Romviel, Sharon, additional, Kanselaar, Karin, additional, Barning, Denn, additional, Venema, Esmee, additional, Chalos, Vicky, additional, Geuskens, Ralph R., additional, van Straaten, Tim, additional, Ergezen, Saliha, additional, Harmsma, Roger R. M., additional, Muijres, Daan, additional, de Jong, Anouk, additional, Berkhemer, Olvert A., additional, Boers, Anna M. M., additional, Huguet, J., additional, Groot, P. F. C., additional, Mens, Marieke A., additional, van Kranendonk, Katinka R., additional, Treurniet, Kilian M., additional, Tolhuisen, Manon L., additional, Alves, Heitor, additional, Weterings, Annick J., additional, Kirkels, Eleonora L. F., additional, Voogd, Eva J. H. F., additional, Schupp, Lieve M., additional, Collette, Sabine L., additional, Groot, Adrien E. D., additional, LeCouffe, Natalie E., additional, Konduri, Praneeta R., additional, Prasetya, Haryadi, additional, Arrarte‐Terreros, Nerea, additional, and Ramos, Lucas A., additional

Published
2021
Full Text
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