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834 results on '"Zhang, Rongrong"'

1. Optimal Frequency in Second Messenger Signaling Quantifying cAMP Information Transmission in Bacteria

Author

Xiong, Jiarui, Wang, Liang, Lin, Jialun, Ni, Lei, Zhang, Rongrong, Yang, Shuai, Huang, Yajia, Chu, Jun, and Jin, Fan

Subjects
Physics - Biological Physics, Quantitative Biology - Molecular Networks, J.2.4
Abstract

Bacterial second messengers are crucial for transmitting environmental information to cellular responses. However, quantifying their information transmission capacity remains challenging. Here, we engineer an isolated cAMP signaling channel in Pseudomonas aeruginosa using targeted gene knockouts, optogenetics, and a fluorescent cAMP probe. This design allows precise optical control and real-time monitoring of cAMP dynamics. By integrating experimental data with information theory, we reveal an optimal frequency for light-mediated cAMP signaling that maximizes information transmission, reaching about 40 bits/h. This rate correlates strongly with cAMP degradation kinetics and employs a two-state encoding scheme. Our findings suggest a mechanism for fine-tuned regulation of multiple genes through temporal encoding of second messenger signals, providing new insights into bacterial adaptation strategies. This approach offers a framework for quantifying information processing in cellular signaling systems., Comment: 33 pages, 4 figures

Published
2024

14. On Existence Theorems for Conditional Inferential Models

Author

Zhang, Rongrong, Zhu, Michael Y., and Liu, Chuanhai

Subjects
Mathematics - Statistics Theory, Statistics - Methodology
Abstract

The framework of Inferential Models (IMs) has recently been developed in search of what is referred to as the holy grail of statistical theory, that is, prior-free probabilistic inference. Its method of Conditional IMs (CIMs) is a critical component in that it serves as a desirable extension of the Bayes theorem for combining information when no prior distribution is available. The general form of CIMs is defined by a system of first-order homogeneous linear partial differential equations (PDEs). When admitting simple solutions, they are referred to as regular, whereas when no regular CIMs exist, they are used as the so-called local CIMs. This paper provides conditions for regular CIMs, which are shown to be equivalent to the existence of a group-theoretical representation of the underlying statistical model. It also establishes existence theorems for CIMs, which state that under mild conditions, local CIMs always exist. Finally, the paper concludes with a simple example and a few remarks on future developments of CIMs for applications to popular but inferentially nontrivial statistical models.

Published
2023

33. 植物油作为食用油和工业润滑油 氧化稳定性评价的研究进展Research progress on oxidation stability evaluation of vegetable oils as edible oils and industrial lubricants

Author

张容容，刘超，杨驷承，刘婷，刘建芳 ZHANG Rongrong, LIU Chao, YANG Sicheng, LIU Ting, LIU Jianfang

Subjects
植物油；食用油；工业润滑油；氧化稳定性, vegetable oil, edible oil, industrial lubricant, oxidation stability, Oils, fats, and waxes, TP670-699
Abstract

植物油因较高的营养价值和良好的润滑性可作为食用油和工业润滑油。旨在为评价不同使用功能的植物油的氧化稳定性提供参考，从食用油和工业润滑油两方面综述了植物油氧化稳定性的检测方法，讨论比较检测方法的适用性、优缺点以及植物油在不同行业中氧化稳定性的评价指标和改善方式的差异。作为食用油，过氧化值、酸值和茴香胺值等理化指标以及氧化诱导时间是常用的评价指标；而对于工业润滑油，酸值、运动黏度和起始氧化温度是常用的评价指标。植物油的使用功能不同，其氧化稳定性研究的侧重点不同。针对指标要求的差异性选择合适的研究方法或者联合应用多个方法，对于最大程度发挥植物油的价值有重要意义。The vegetable oils can be used as edible oils and industrial lubricants due to their high nutrition and good lubricity. In order to provide reference for evaluating the oxidation stability of vegetable oils for different use functions, the detection methods for the oxidation stability of vegetable oils were reviewed in terms of both edible oils and industrial lubricants. At the same time, the applicabilities, advantages and disadvantages of detection methods and the differences of evaluation indexes and improvement ways of oxidation stability in different fields were discussed and compared. As edible oils, the physicochemical parameters such as peroxide value, acid value, anisidine value and oxidation induction time are commonly used as evaluation indexes. For industrial lubricants, acid value, kinematic viscosity and initial oxidation temperature are commonly used as evaluation indexes. The research emphases of oxidation stability of vegetable oils are different because of their different functions. It is of great significance to select appropriate research methods or combine several methods according to the difference of index requirements for maximizing the value of vegetable oils.

Published
2023
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