1. Effects of nano-Rhodiola rosea combined with treadmill exercise on anti-exercise fatigue in rats
- Author
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Jibing Wang, Guoyan Zhang, Duona Wang, Yuanyuan Yan, and Qin Yang
- Subjects
Rhodiola rosea ,nano ,anti-exercise fatigue ,free radical ,antioxidant enzyme ,Nutrition. Foods and food supply ,TX341-641 - Abstract
ObjectiveTo explore the potential strategies and mechanisms for enhancing the bioavailability of Rhodiola rosea.Methods36 Sprague–Dawley rats (8-weeks-old) were randomly assigned to six groups (n = 6 per group). Groups I and II received nano-dose forms of R. rosea, groups III and IV received normal dose form of R. rosea, and groups V and VI served as distilled water control groups. Groups II, IV, and VI were combined with moderate -intensity treadmill exercise. Each group received a daily gavage with 0.5 mL of nano -R. rosea solution (0.01 mg/mL), normal R. rosea solution, and distilled water. All rats were subjected to exhaustive swimming after 4 weeks. Outcome measures include GSH-px activity, T-AOC activity, MDA content, hepatic glycogen content, and T-SOD activity.ResultsFor plasma MDA content, group I was lower than group III (p
- Published
- 2024
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