12 results on '"Yasuo IRIE"'
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2. [Untitled]
- Author
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Satoshi KUROKOUCHI, Masayuki OKABE, Mitsuyoshi SAITO, Shinsaku MORITA, Yoshiro SHIOKAWA, Masakazu ICHIKAWA, Seiichiro KANNO, Tatehito USUI, Koichi SUDOH, Tatsuo YOSHINOBU, Hiroshi IWASAKI, Hiroaki TANAKA, Kimio OKUNO, Tadao MIURA, Touru SUMIYA, Katsuya HONDA, Shun-ichiro TANAKA, Yukio INOKUTI, Kazuhiro SUZUKI, Nastuki TAKAHASHI, Osamu OHKUBO, Yoshihiro SAWAHIRA, Akishige SATO, Naoto KIKUCHI, Eiji KUSANO, Hidehito NANTO, Akira KINBARA, Tetsuya NARUSHIMA, Akiko ITAKURA, Takaya KAWABE, Masahiro KITAJIMA, Masaru KITAGAWA, Toshiyuki OHYA, Hiroyuki NAGAHAMA, Sei-ichiroh YOKOYAMA, Ichiro ARAKAWA, Takashi ADACHI, Takato HIRAYAMA, Koichiro MITSUKE, Makoto SAKURAI, Sin-ichi IGARASHI, Yukiko ABE, Yasuo IRIE, Miyuki KAMBE, Aki TOSAKA, Satoko HAMAMATSU, Satoshi ISHII, Yoshiyuki NORIMITSU, Toshimi SUTOU, Noriyuki UBUKATA, Yoshihiro OINUMA, Shigeru SAITO, Masaaki KATOH, Kenichi TAJIMA, Daisuke HORIMOTO, Takeo OHTE, Akira KOJIMA, Seiya OHI, Takashi SHIOYA, Kazuhiko KOBAYASHI, Hidefumi NAKAJIMA, Satoshi YOKOYAMA, Hiroyuki OBARA, Hajime SAKAI, Yasuhiro OGOSHI, Takuro KOIKE, Koichiro UCHIMURA, Hitoshi TABATA, Tomoji KAWAI, Yutaka HIBINO, Guochun XU, Yasuo SUZUKI, Masao TANIHARA, Yukio IMANISHI, Shigemi SUGINUMA, Masahiro HIRATA, Hitoshi AKIMICHI, Kyoko TAKEUCHI, Yutaka TUZI, Masahiro TOSA, Akira KASAHARA, Kyung Sub LEE, Kazuhiro YOSHIHARA, Tomonari TANAKA, Tadashi SAWADA, Wataru SUGIYAMA, Koyu OTA, Daisuke YAMAUCHI, Shinobu SATO, Masatoshi TANAKA, Masaaki KISHIDA, Masahiko TOMITORI, Kiyotaka ASAKURA, Wang-Jae CHUN, Yasuhiro IWASAWA, Kiminori KAKITANI, Hiroko KAJI, Yoichiro YAGI, Akio YOSHIMORI, Akio OKAMOTO, Toshikazu NOSAKA, Masaaki YOSHITAKE, Souichi OGAWA, Shigeaki NAKAMURA, Nobuo SAITO, Shoji YOSHIOKA, Isamu NAKAAKI, Hideo HASEGAWA, Toshiyuki MIHARA, Shoichi MOCHIZUKI, Shigeharu TAMURA, Hironori KOBAYASHI, Ryoji MAKABE, Tadashi ISHIDA, Yoshiyuki SATO, Masanori ANDO, Tetsuhiko KOBAYASHI, Ayako HIOKI, Kazuki NATSUKAWA, Koji INOUE, Yoshikazu NAKAYAMA, Takayuki SATO, Shinichiro MICHIZONO, Yoshio SAITO, Shinichi KOBAYASHI, Kiyohide KOKUBUN, Yuuki WATANABE, Heizo TOKUTAKA, Kikuo FUJIMURA, Tatsuo SHIMIZU, Yasushiro NISHIOKA, Hideki TANAKA, Hiroyuki WAKIMOTO, Toshihiko MIYAZAKI, Goro MIZUTANI, Sukekatsu USHIODA, Yoshitake YAMAGUCHI, Satoru TAKAKUSAGI, Makoto KATO, Yuji SAKAI, Akira KUROKAWA, Shingo ICHIMURA, Ken NAKAMURA, Takanori AOKI, Syogo TODA, Akio SUZUKI, Tatsuhiko MATSUSHITA, Masahiro OKUDA, Kazuaki HAMAJI, Yoshiharu KAKEHI, Tsutom YOTSUYA, Norihiro MATSUOKA, Yoshitsugu TSUTSUMI, Hideki TOMIOKA, Yoshio OKAMOTO, Kensuke MURAI, Masato YASUMOTO, Norimasa UMESAKI, Hirohiko NAKANO, Toshiaki TATSUTA, Jiro MATSUO, Isao YAMADA, Hiroyuki MAGARA, Osamu TABATA, Touichi HATANO, Masatoshi KOTERA, Kiyoshi YAMAGUCHI, Naohiro HORII, Kunio OKIMURA, Akira SHIBATA, Hiroshi MURAKAMI, Ikuya KAMEYAMA, Satoru SUKENOBU, Kazuhiko MIMOTO, Takashi MATSUMOTO, Takafumi YOSHIKAWA, Masato KIUCHI, Seiichi GOTO, Masatoshi OHBA, Yoshiaki AGAWA, Kazuma SHIBUTANI, Hiroshi TSUJI, Yasuhito GOTOH, Junzo ISHIKAWA, Hiroki KAWADA, Hiroyuki KITSUNAI, Nobuo TSUMAKI, Masanori KATSUYAMA, Shinichi SUZUKI, Katsuto TANAHASHI, Yuichi KAWAMURA, Naohisa INOUE, Yoshikazu HOMMA, Michimasa KIKUCHI, Kazumasa ISHIKAWA, Teiichi HOMMA, Yoshinori SUGANUMA, Nan LI, Katsuyoshi KOBAYASHI, Nobuyoshi SAKAKIBARA, Yoshiki UENO, Masayuki AOKI, Toshiaki YASUI, Keito MORIMOTO, Hirokazu TAHARA, Takao YOSHIKAWA, Hidekazu KODERA, Masahiko UOTA, Yoshihiro SATOH, Tomio KUBO, Kozo MOCHIJI, Naoshi ITABASHI, Hiroshi SHIMIZU, Shunsuke OHTANI, Kazuhiko OKUNO, and Nobuo KOBAYASHI
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Electrical and Electronic Engineering ,Condensed Matter Physics ,Surfaces, Coatings and Films - Published
- 1999
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3. Observation by Extremely-low-current Low Energy Electron Diffraction of the Physisorbed Rare Gas Layer Growth
- Author
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Yukiko Abe, Ichiro Arakawa, Sin-ichi Igarashi, Yasuo Irie, and Takato Hirayama
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Low-energy electron diffraction ,Chemistry ,Detector ,Analytical chemistry ,Substrate (electronics) ,Condensed Matter Physics ,Molecular physics ,Surfaces, Coatings and Films ,Overlayer ,Ellipsometry ,Cathode ray ,Electrical and Electronic Engineering ,Single crystal ,Layer (electronics) - Abstract
We have developed an eXtremely-low-current Low Energy Electron Diffraction (XLEED) apparatus equipped with a micro-channel plate and a position-sensitive detector which reduces electron beam damage and charge-up effects and makes it possible to study the structure of physisorbed films. This XLEED system is combined with the ellipsometer system which monitors the thickness of a physisorbed film. We observed Xe overlayer on Ag (111) and grahpite (0001) surfaces. We found that a thick Xe films on Ag (111) showed a single crystal structure which keeps relative orientation to the substrate.
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- 1998
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4. [Untitled]
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Michio MINATO, Yoshio ITOH, Shingo ICHIMURA, Kiyohide KOKUBUN, Masahiro HIRATA, Sonoko TSUKAHARA, Kazuya SAITO, Yoshinao IKEDA, Yoshio SAITO, Kowashi WATANABE, Hiroshi SAEKI, Mitsuhiro MASAKI, Yasuaki SUZUKI, Yukiko TANIUCHI, Takashi NODA, Michio MAENO, Suck Hee BE, Haruo OHKUMA, Masahiro TOSA, Akira KASAHARA, Kazuhiro YOSHIHARA, Seiichiro KANNO, Hiroyuki KITSUNAI, Nobuo TSUMAKI, Masaaki NAKAYAMA, Hitoshi NISHIMURA, Kenji SHIRAI, Shinichi KOBAYASHI, Norio OGIWARA, Keiichi OHIRA, Takayuki SATO, Shinichiro MICHIZONO, Shigemi SUGINUMA, Migaku TAKAHASHI, Akio OKAMOTO, Toshikazu NOSAKA, Masaaki YOSHITAKE, Souichi OGAWA, Kazuhiko KOBAYASHI, Masatoshi NOGUCHI, Hidefumi NAKAJIMA, Hiroyuki OBARA, Hajime SAKAI, Yasuhiro OGOSHI, Takuro KOIKE, Hideo HASEGAWA, Yukio INOKUTI, Kazuhiro SUZUKI, Osamu OHKUBO, Natsuki TAKAHASHI, Masayuki TERAI, Norichika HASEGAWA, Masahiko OKUZAWA, Chuhei OSHIMA, Shigeki OTANI, Kenji ODAKA, Osamu SATOH, Yoshiro SHIOKAWA, Masakazu ICHIKAWA, Kenya AKAISHI, Kazuhiro EZAKI, Yusuke KUBOTA, Osamu MOTOJIMA, Masakatsu KITANI, Akira KUROKAWA, Hiroko KAJI, Kiminori KAKITANI, Yoichiro YAGI, Akio YOSHIMORI, Takanori AOKI, Shogo TODA, Kazuaki HAMAJI, Akio SUZUKI, Tatsuhiko MATSUSHITA, Masahiro OKUDA, Daisuke TANAKA, Takeshi FUJIWARA, Mituaki MAEDA, Nobuhiko TAKEHARA, Mitsutaka HIKIDA, Yasuhiro IGASAKI, Akishige SATO, Masaru KITAGAWA, Yasunobu KURODA, Eiji KUSANO, Akira KINBARA, Taizo KAWAUCHI, Katsuyuki FUKUTANI, Tatsuo OKANO, Shunji KISHIMOTO, Xiaowei ZHANG, Toyosei KAWASAKI, Daisuke SAKAI, Hiroshi ITOH, Takeo ICHINOKAWA, Toshuu AN, Hiroshi KUBO, Yasuhito GOTOH, Hiroshi TSUJI, Junzo ISHIKAWA, Youiti YAMAMOTO, Toshiaki MIYOKAWA, Nobuaki TAMURA, Tadao MIURA, Touru SUMIYA, Haruko FUJINUMA, Shun-ichiro TANAKA, Hiroyuki YOSHIKI, Teruhiko TSUTSUI, Tetsu OKAMOTO, Seiichi WATANABE, Yukio OKAMOTO, Hiroki KAWADA, Kaoru IJIMA, Seigi MIZUNO, Saburo SHIMIZU, Koh FUWA, Seiji SEKI, Kazunobu HAYAKAWA, Heizo TOKUTAKA, Kazuyuki IWAMOTO, Kikuo FUJIMURA, Toru WATANABE, Satoru KISHIDA, Ken NAKAMURA, Yoshiyuki IGARI, Shinji ISHIDZUKA, Tetsuroh MINE, Tsuyoshi TAKAOKA, Tomohide TAKAMI, Isao KUSUNOKI, Akira HAYAMA, Kazuyoshi IMOTO, Takato HIRAYAMA, Ichiro ARAKAWA, Takashi ADACHI, Koichiro MITSUKE, Makoto SAKURAI, Takashi MOMOSE, Eishuu HAYASAKA, Katsuhiro SAITOU, Katsuya NAGAYAMA, Sin'ya ABE, Kunio OKIMURA, Naoki YASUMARU, Yukiko ABE, Sin-ichi IGARASHI, Yasuo IRIE, Katsumi SUZUKI, Eiji ROKUTA, Tomohiro HAYASHI, Atsushi ITO, Toshio SAKURAI, Masuaki MATSUMOTO, Natsuo TATSUMI, Tadashi ITOYAMA, and Masaomi UMEZAWA
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Electrical and Electronic Engineering ,Condensed Matter Physics ,Surfaces, Coatings and Films - Published
- 1998
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5. Genetic dissection of 'OLETF,' a rat model for non-insulin-dependent diabetes mellitus: quantitative trait locus analysis of (OLETF x BN) x OLETF
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Atsushi B. Tsuji, Toshihisa Takagi, Yusuke Nakamura, Shiro Okuno, Naohide Kanemoto, Haretsugu Hishigaki, Yasuo Irie, Yuki Yamasaki, Takeshi K. Watanabe, Akira Tanigami, Ayako Mizoguchi-Miyakita, Keiko Oga, and Ei Ichi Takahashi
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Blood Glucose ,Male ,medicine.medical_specialty ,X Chromosome ,Genotype ,Genetic Linkage ,Rats, Inbred OLETF ,Biology ,Quantitative trait locus ,Insulin resistance ,Quantitative Trait, Heritable ,Internal medicine ,Diabetes mellitus ,Rats, Inbred BN ,Genetics ,medicine ,Hyperinsulinemia ,Glucose homeostasis ,Animals ,Obesity ,X chromosome ,Crosses, Genetic ,Body Weight ,Chromosome Mapping ,medicine.disease ,Rats ,Disease Models, Animal ,Endocrinology ,Postprandial ,Phenotype ,Adipose Tissue ,Diabetes Mellitus, Type 2 ,Female ,Lod Score - Abstract
To identify genetic determinants relevant to non-insulin-dependent diabetes mellitus (NIDDM), we performed a genome-wide analysis for quantitative trait loci (QTLs) using 359 backcross progeny of the Otsuka Long-Evans Tokushima Fatty (OLETF) rat. The OLETF strain is a well-studied animal model of obese NIDDM, with features of hyperinsulinemia, hyperglycemia, insulin resistance, and abundant abdominal fat. Our extensive genomic scanning with 218 markers revealed nine significant QTLs, including a strong determinant of obesity on chromosome 1 (Dmo1: LOD = 13.99, for body weight). Two highly significant QTLs for glucose homeostasis were found, one on chromosome 1 (Dmo4 LOD = 7.16, for postprandial glucose level) and the other on chromosome X (Dmo11/Odb1: LOD = 7.81, for postprandial glucose level). These data are comparable to results of our previous studies of the OLETF rat.
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- 1999
6. Propagation of Stress Waves in an Elastic/Viscoplastic Cylindrical Body Containing a Spherical Cavity
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Shinji TANIMURA, Yasuo IRIE, and Yoichi KITAMURA
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Mechanics of Materials ,Mechanical Engineering ,General Materials Science - Published
- 1983
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7. Syntheses and PMR Studies of Pentachlorocyclohexanecarbonitrile, Pentachloromethylcyclohexane and Tetrachlorodimethylcyclohexane
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Minoru Nakajima, Makoto Kiso, Norio Kurihara, Yuzuru Sanemitsu, and Yasuo Irie
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chemistry.chemical_compound ,Nitrile ,Chemistry ,Stereochemistry ,Reagent ,Maleic anhydride ,General Agricultural and Biological Sciences ,Spectroscopy ,Medicinal chemistry ,General Biochemistry, Genetics and Molecular Biology - Abstract
dl-(1245/36)-2,3,4,5,6-Pentachlorocyclohexanecarbonitrile was synthesized from (1234/ 56)-1,4,5,6-tetrachloro-2,3-epoxycyclohexane (α-BTC cis-epoxide). dl-(1245/36)-2,3,4,5,6-Pentachloro-1-methylcyclohexane was synthesized from the nitrile via dl-(1245/36)-2,3,4,5,6-pentachlorocyclohexylmethanol, the structure of which was confirmed by PMR spectroscopy using spin decoupling techniques and the shift reagent, Eu(DPM)3. This series of compounds was shown to have the same configuration as γ-BHC. The conformational equilibrium of these compounds is discussed. dl-(1245/36)-2,3,5,6-Tetrachloro-1,4-dimethyl-cyclohexane was synthesized by a stepwise route involving a Diels-Alder reaction of trans,trans-hexadiene-2,4 with maleic anhydride.
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- 1975
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8. Synthesis of 2',3'-dideoxyuridine via deoxygenation of 2',3'-O-(methoxymethylene)uridine
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Yasuo Irie, Kenzo Yokozeki, Naohiko Yasuda, Hiroshi Shiragami, and Hideyuki Shirae
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chemistry.chemical_compound ,Biochemistry ,Chemistry ,Stereochemistry ,Organic Chemistry ,Deoxygenation ,Nucleoside ,Uridine - Published
- 1988
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9. Production of 2',3'-dideoxyadenosine and 2',3'-dideoxyinosine from 2',3'-dideoxyuridine and the corresponding purine bases by resting cells of Escherichia coli AJ 2595
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Hideyuki Shirae, Yasuo Irie, Kenzo Yokozeki, Katsunori Kobayashi, Naohiko Yasuda, and Hiroshi Shiragami
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Purine ,Stereochemistry ,medicine.disease_cause ,Antiviral Agents ,Applied Microbiology and Biotechnology ,2'3' dideoxyinosine ,chemistry.chemical_compound ,Escherichia coli ,medicine ,Hypoxanthine ,Bacteria ,Ecology ,Dideoxynucleosides ,Temperature ,Hydrogen-Ion Concentration ,Dideoxyadenosine ,Didanosine ,Kinetics ,chemistry ,Nucleoside ,Cytosine ,Research Article ,Food Science ,Biotechnology - Abstract
A novel microbial method for the production of 2',3'-dideoxynucleosides by transdideoxyribosylation has been developed. By screening microorganisms producing 2',3'-dideoxyadenosine (DDA) from 2',3'-dideoxyuridine (DDU) and adenine, Escherichia coli AJ 2595 was selected as the best producer. Optimal pH and temperature for the DDA-producing reaction were ca. 6.5 and 50 degrees C, respectively. Pi seemed to be an essential factor for the reaction, and its optimal concentration was ca. 25 mM. Moreover, polyethylene glycol had a notable effect on DDA production. Under the best conditions established, 52 mM DDA was obtained from 100 mM DDU and 100 mM adenine after 48 h of incubation from resting cells of E. coli AJ 2595. This strain could also produce 2',3'-dideoxynucleosides, such as 2',3'-dideoxyinosine (DDI), 2',3'-dideoxyguanosine, and 2',3'-dideoxythymidine, from DDU and the corresponding bases. In particular, this strain could produce DDI in high yield (ca. 32 mM from 100 mM DDU and 100 mM hypoxanthine) after 24 h of incubation. However, 2',3'-dideoxycytidine was not produced from DDU and cytosine by resting cells of E. coli AJ 2595.
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- 1989
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10. Metabolic fate of carteolol hydrochloride (OPC-1085), a new β-adrenergic blocking agent. VI. Pharmacokinetics of carteolol in rat, dog, rabbit and man
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Seiji MORITA, Yasuo IRIE, Sachiko SAKURAGI, Hideaki KOHRI, and Hiroshi NISHINO
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Pharmacology ,Route of administration ,Beta-adrenergic blocking agent ,Pharmacokinetics ,Elimination rate constant ,Oral administration ,Chemistry ,medicine ,Carteolol ,Carteolol Hydrochloride ,Intestinal absorption ,medicine.drug - Abstract
The kinetics (absorption, distribution and excretion) of carteolol were investigated after oral and intravenous administration to man, rats, Beagle dogs and rabbits. The half-life of carteolol in plasma was 1.22 approximately 1.45 hr in rats, 1.73 approximately 2.08 hr in dogs and 1.42 approximately 1.43 hr in rabbits, and was independent of the route of administration. The absorption rate constants, obtained from log(C1-C) approximately time plot, after oral administration were 1.89 hr-1 in rats, 1.04 hr-1 in dogs and 1.54 hr-1 in rabbits. There were no differences between tablet and film coated tablet in the pharmacokinetic parameters of carteolol in man after oral 30 mg (tablet or film coated tablet) administration [half life (t1/2)=4.50 hr (tablet), 4.30 hr (film coated tablet), elimination rate constant (k2) equals 0.154 hr-1 (tablet), 0.161 hr-1 (film coated tablet)]. The elimination rate constant, obtained from Sigma-minus plot after 2, 5 and 10 mg oral administration, was 0.137 approximately 0.160 hr-1.
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- 1977
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11. The tissue content of cyclic AMP in rats after microwave irradiation in vivo
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Tetsumi Hosokawa, Yasuo Irie, Takehiro Igawa, and Yuichi Saitoh
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Male ,Agonist ,medicine.medical_specialty ,Time Factors ,Procaterol ,medicine.drug_class ,Adrenergic beta-Antagonists ,In vivo ,Internal medicine ,Freezing ,Cyclic AMP ,medicine ,Animals ,Tissue Distribution ,Irradiation ,Microwaves ,Pentobarbital ,Fixation (histology) ,Pharmacology ,Lung ,Chemistry ,Skeletal muscle ,Liquid nitrogen ,Rats ,Endocrinology ,medicine.anatomical_structure ,3',5'-Cyclic-AMP Phosphodiesterases ,Biophysics ,medicine.drug - Abstract
When anesthetized rats were exposed to microwave (power output 1.3 kw, frequency 2,450 MHz), the cyclic AMP phosphodiesterase activity showed a rapid decline in the skeletal muscle, heart, trachea and lung; no activity essentially could be detected after a 30 sec irradiation. Cyclic AMP levels in these tissues also decreased rapidly to constant values within 30 sec. Concentrations of cyclic AMP in the heart, skeletal muscle, trachea and lung measured by the tissue fixation with liquid nitrogen were approximately 3, 3, 4 and 4 times higher than those after microwave irradiation, respectively. The intravenous injection of procaterol (1 mu mol/kg), a beta 2-adrenoceptor agonist, caused a 6-fold increase in the trachea cyclic AMP level when measured after microwave fixation but only a 2-fold increase when measured after liquid nitrogen fixation. It is concluded that rapid tissue fixation by microwave irradiation may provide a useful means for obtaining reliable values of the tissue cyclic AMP content.
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- 1980
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12. Fatigue Crack Propagation under Controlled Stress Intensity Factor (II)
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Tetsuo Ogawa, Yasuo Irie, and Hiroshi Itagaki
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Crack closure ,Materials science ,business.industry ,Structural mechanics ,Fracture mechanics ,Growth rate ,Structural engineering ,Mechanics ,Paris' law ,business ,Stress intensity factor ,Vibration fatigue ,Stress concentration - Abstract
The behavior of the fatigue crack under the narrow band random stress intensity factor was studied experimentally. It was found that stress intensity factor governs the fatigue crack growth rate under random load process as well as under deterministic load sequences, and the crack growth rate in the short range showed noticeable fluctuation while that in the long range was almost constant implying that Miner's rule could be applied for the crack growth provided that the constants were determined from random fatigue test.A small digital system with a micro-CPU and the associated software developed for this study was found suitable for random fatigue tests.
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- 1974
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