203 results on '"Yao, Ni"'
Search Results
2. Multi-wavelength switchable single-frequency hyper Raman microlasers
- Author
-
Li, Chuntao, Yao, Ni, Lin, Jintian, Gao, Renhong, Guan, Jianglin, Zhao, Guanghui, Li, Minghui, Wang, Min, Qiao, Lingling, and Cheng, Ya
- Subjects
Physics - Optics - Abstract
Multi-wavelength switchable single-frequency microlasers in a broad spectral range are highly desirable for integrated photonic applications due to their dynamic switching functionality, narrow linewidth, and high side-mode-suppression-ratio (SMSR). Here, a strategy based on highly efficient successive excitation of different stimulated multi-photon hyper-Raman scattering (SMPHRS) processes is proposed to generate multi-wavelength switchable single-frequency hyper-Raman microlasers. This is achieved through collective precise dispersion management for arranging excitation wavelengths to trigger different phase-matched SMPHRS processes in order, mode-hopping-free tuning of the pump wavelength within a wide range of 0.75 nm by leveraging strong thermo-optical broadening of ultra-high Q modes, and simultaneously suppressing harmonics generation in a lithium niobate microcavity with high second-order nonlinearity. As a result, under continuous-wave laser pump at a low level of only 3.9 mW, SMPHRS processes from two- to five-photons emerged step by step and almost depleted previously generated multi-photon Raman signal. Consequently, four-wavelength dynamically switchable single-mode lasing from near infrared (857 nm) to ultraviolet (350 nm) spanning beyond the record range (~500 nm) with high SMSRs >35 dB is reported., Comment: 17 pages,5 figures, and 1 table
- Published
- 2024
3. A Robust Deep Learning Method with Uncertainty Estimation for the Pathological Classification of Renal Cell Carcinoma Based on CT Images
- Author
-
Yao, Ni, Hu, Hang, Chen, Kaicong, Huang, Huan, Zhao, Chen, Guo, Yuan, Li, Boya, Nan, Jiaofen, Li, Yanting, Han, Chuang, Zhu, Fubao, Zhou, Weihua, and Tian, Li
- Published
- 2024
- Full Text
- View/download PDF
4. Integrated multi-color Raman microlasers with ultra-low pump levels in single high-Q lithium niobate microdisks
- Author
-
Zhao, Guanghui, Lin, Jintian, Fu, Botao, Gao, Renhong, Li, Chuntao, Yao, Ni, Guan, Jianglin, Li, Minghui, Wang, Min, Qiao, Lingling, and Cheng, Ya
- Subjects
Physics - Optics - Abstract
Photonic integrated Raman microlasers, particularly discrete multi-color lasers which are crucial for extending the emission wavelength range of chip-scale laser sources to much shorter wavelength, are highly in demand for various spectroscopy, microscopy analysis, and biological detection. However, integrated multi-color Raman microlasers have yet to be demonstrated because of the requirement of high-Q microresonators possessing large second-order nonlinearity and strong Raman phonon branches and the challenging in cavity-enhanced multi-photon hyper-Raman scattering parametric process. In this work, integrated multi-color Raman lasers have been demonstrated for the first time at weak pump levels, via the excitation of high-Q (>6 X 10^6) phase-matched modes in single thin-film lithium niobate (TFLN) microresonators by dispersion engineering. Raman lasing was observed at 1712 nm for a 1546-nm pump threshold power of only 620 uW. Furthermore, multi-color Raman lasers were realized at discrete wavelengths of 1712 nm, 813 nm, 533 nm and 406 nm with pump levels as low as 1.60 mW, which is more than two order of magnitude lower than the current records (i.e., 200 mW) in bulk resonators, allowed by the fulfillment of the requisite conditions consisting of broadband natural phase match, multiple-resonance and high Q-factors., Comment: 16 pages,4 figures
- Published
- 2023
5. Multidimensional free shape-morphing flexible neuromorphic devices with regulation at arbitrary points
- Author
-
Jiaqi Liu, Chengpeng Jiang, Qianbo Yu, Yao Ni, Cunjiang Yu, and Wentao Xu
- Subjects
Science - Abstract
Abstract Biological neural systems seamlessly integrate perception and action, a feat not efficiently replicated in current physically separated designs of neural-imitating electronics. This segregation hinders coordination and functionality within the neuromorphic system. Here, we present a flexible device tailored for neuromorphic computation and muscle actuation. Each individual device component emulates essential synaptic functions for neural computing, while the collective ensemble replicates muscle actuation in response to efferent neuromuscular commands. These properties stem from densely-packed, hydrophilic nanometer-sized channels, and the erection of a high-entropy, intricately silver nanowires to capture and store of hydrated cations. Leveraging the remarkable deformation effect, we demonstrate hazard detection-avoidance robot, and multidimensional integration for arbitrary programmed shapes like 360° panoramic information capture and soft-bodied biological deformations wherein localized responses to stimuli are harmoniously integrated to achieve arbitrary coordinated motion. These results provide a significant avenue for the development of future flexible electronics and bio-inspired systems.
- Published
- 2025
- Full Text
- View/download PDF
6. A Robust Deep Learning Method with Uncertainty Estimation for the Pathological Classification of Renal Cell Carcinoma based on CT Images
- Author
-
Yao, Ni, Hu, Hang, Chen, Kaicong, Zhao, Chen, Guo, Yuan, Li, Boya, Nan, Jiaofen, Li, Yanting, Han, Chuang, Zhu, Fubao, Zhou, Weihua, and Tian, Li
- Subjects
Electrical Engineering and Systems Science - Image and Video Processing ,Computer Science - Computer Vision and Pattern Recognition ,Computer Science - Machine Learning ,Physics - Medical Physics ,Quantitative Biology - Quantitative Methods - Abstract
Objectives To develop and validate a deep learning-based diagnostic model incorporating uncertainty estimation so as to facilitate radiologists in the preoperative differentiation of the pathological subtypes of renal cell carcinoma (RCC) based on CT images. Methods Data from 668 consecutive patients, pathologically proven RCC, were retrospectively collected from Center 1. By using five-fold cross-validation, a deep learning model incorporating uncertainty estimation was developed to classify RCC subtypes into clear cell RCC (ccRCC), papillary RCC (pRCC), and chromophobe RCC (chRCC). An external validation set of 78 patients from Center 2 further evaluated the model's performance. Results In the five-fold cross-validation, the model's area under the receiver operating characteristic curve (AUC) for the classification of ccRCC, pRCC, and chRCC was 0.868 (95% CI: 0.826-0.923), 0.846 (95% CI: 0.812-0.886), and 0.839 (95% CI: 0.802-0.88), respectively. In the external validation set, the AUCs were 0.856 (95% CI: 0.838-0.882), 0.787 (95% CI: 0.757-0.818), and 0.793 (95% CI: 0.758-0.831) for ccRCC, pRCC, and chRCC, respectively. Conclusions The developed deep learning model demonstrated robust performance in predicting the pathological subtypes of RCC, while the incorporated uncertainty emphasized the importance of understanding model confidence, which is crucial for assisting clinical decision-making for patients with renal tumors. Clinical relevance statement Our deep learning approach, integrated with uncertainty estimation, offers clinicians a dual advantage: accurate RCC subtype predictions complemented by diagnostic confidence references, promoting informed decision-making for patients with RCC., Comment: 16 pages, 6 figures
- Published
- 2023
7. Generation of Kerr soliton microcomb in a normally dispersed lithium niobate microdisk resonator by mode trimming
- Author
-
Fu, Botao, Gao, Renhong, Yao, Ni, Zhang, Haisu, Li, Chuntao, Lin, Jintian, Wang, Min, Qiao, Lingling, and Cheng, Ya
- Subjects
Physics - Optics - Abstract
Anomalous microresonator dispersion is mandatory for Kerr soliton microcomb formation, which depends critically on the geometry of the microresonator and can hardly be tuned after the structure is made. To date, cavity-based microcombs have only been generated with fundamental whispering gallery modes (WGMs) of anomalous dispersion in microresonators. Moreover, microcomb generation in highly Raman-active platforms such as lithium niobate (LN) microresonators frequently suffers from stimulated Raman scattering and mode crossing due to the existence of multiple families of high-order WGMs. Here, we reveal a unique Kerr soliton microcomb generation mechanism through mode trimming in a weakly perturbed LN microdisk resonator. Remarkably, the soliton comb is generated with fundamental WGMs of normal dispersion and free from the mode crossing and Raman scattering effects. A robust soliton with a spectrum spanning from 1450 nm to 1620 nm at an on-chip pump power of 35 mW. Our discovery offers a powerful solution to circumvent the stringent requirements on high-precision dispersion engineering and termination of Raman excitation for soliton generation in the high-Q microdisk., Comment: 16 pages,and 5 figures
- Published
- 2023
8. MLA-BIN: Model-level Attention and Batch-instance Style Normalization for Domain Generalization of Federated Learning on Medical Image Segmentation
- Author
-
Zhu, Fubao, Tian, Yanhui, Han, Chuang, Li, Yanting, Nan, Jiaofen, Yao, Ni, and Zhou, Weihua
- Subjects
Electrical Engineering and Systems Science - Image and Video Processing ,Computer Science - Computer Vision and Pattern Recognition - Abstract
The privacy protection mechanism of federated learning (FL) offers an effective solution for cross-center medical collaboration and data sharing. In multi-site medical image segmentation, each medical site serves as a client of FL, and its data naturally forms a domain. FL supplies the possibility to improve the performance of seen domains model. However, there is a problem of domain generalization (DG) in the actual de-ployment, that is, the performance of the model trained by FL in unseen domains will decrease. Hence, MLA-BIN is proposed to solve the DG of FL in this study. Specifically, the model-level attention module (MLA) and batch-instance style normalization (BIN) block were designed. The MLA represents the unseen domain as a linear combination of seen domain models. The atten-tion mechanism is introduced for the weighting coefficient to obtain the optimal coefficient ac-cording to the similarity of inter-domain data features. MLA enables the global model to gen-eralize to unseen domain. In the BIN block, batch normalization (BN) and instance normalization (IN) are combined to perform the shallow layers of the segmentation network for style normali-zation, solving the influence of inter-domain image style differences on DG. The extensive experimental results of two medical image seg-mentation tasks demonstrate that the proposed MLA-BIN outperforms state-of-the-art methods., Comment: 9 pages, 8 figures, 2 tables
- Published
- 2023
9. Case report: Basal cell carcinoma arising within the nevus sebaceous: report of 4 cases and literature review
- Author
-
Tianbing Lei, Yonghong Lu, Yanyan Feng, and Yao Ni
- Subjects
nevus sebaceous ,basal cell carcinoma ,malignant degeneration ,gene ,ultraviolet ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Nevus sebaceous (NS) is a congenital hamartoma characterized by the presence of skin structures, including the epidermis, sebaceous glands, and hair follicles. NS predominantly occurs on the scalp and has the potential to give rise to secondary tumors, with a small proportion being malignant; the most frequently observed malignant tumor associated with NS is basal cell carcinoma. In this report, we retrospectively present four cases of sebaceous nevus on the scalp complicated by basal cell carcinoma. The pathological diagnoses were unequivocal in all four patients, who exhibited typical clinical manifestations, with all cases localized to the left parietotemporal region of the scalp. The etiology of NS may be linked to genetic mutations or ultraviolet exposure. Treatment options vary, with surgical resection likely being the most common method of eradication.
- Published
- 2025
- Full Text
- View/download PDF
10. Incremental Value and Interpretability of Radiomics Features of Both Lung and Epicardial Adipose Tissue for Detecting the Severity of COVID-19 Infection
- Author
-
Yao, Ni, Tian, Yanhui, Neves, Daniel Gama das, Zhao, Chen, Mesquita, Claudio Tinoco, Martins, Wolney de Andrade, Santos, Alair Augusto Sarmet Moreira Damas dos, Li, Yanting, Han, Chuang, Zhu, Fubao, Dai, Neng, and Zhou, Weihua
- Subjects
Electrical Engineering and Systems Science - Image and Video Processing ,Computer Science - Computer Vision and Pattern Recognition - Abstract
Epicardial adipose tissue (EAT) is known for its pro-inflammatory properties and association with Coronavirus Disease 2019 (COVID-19) severity. However, current EAT segmentation methods do not consider positional information. Additionally, the detection of COVID-19 severity lacks consideration for EAT radiomics features, which limits interpretability. This study investigates the use of radiomics features from EAT and lungs to detect the severity of COVID-19 infections. A retrospective analysis of 515 patients with COVID-19 (Cohort1: 415, Cohort2: 100) was conducted using a proposed three-stage deep learning approach for EAT extraction. Lung segmentation was achieved using a published method. A hybrid model for detecting the severity of COVID-19 was built in a derivation cohort, and its performance and uncertainty were evaluated in internal (125, Cohort1) and external (100, Cohort2) validation cohorts. For EAT extraction, the Dice similarity coefficients (DSC) of the two centers were 0.972 (+-0.011) and 0.968 (+-0.005), respectively. For severity detection, the hybrid model with radiomics features of both lungs and EAT showed improvements in AUC, net reclassification improvement (NRI), and integrated discrimination improvement (IDI) compared to the model with only lung radiomics features. The hybrid model exhibited an increase of 0.1 (p<0.001), 19.3%, and 18.0% respectively, in the internal validation cohort and an increase of 0.09 (p<0.001), 18.0%, and 18.0%, respectively, in the external validation cohort while outperforming existing detection methods. Uncertainty quantification and radiomics features analysis confirmed the interpretability of case prediction after inclusion of EAT features., Comment: 20 pages, 7 figures
- Published
- 2023
11. Modes trimming and clustering in a weakly perturbed high-Q whispering gallery microresonator
- Author
-
Fu, Botao, Gao, Renhong, Lin, Jintian, Yao, Ni, Zhang, Haisu, Wang, Min, Qiao, Lingling, Fang, Wei, and Cheng, Ya
- Subjects
Physics - Optics - Abstract
In general, a high-Q microresonator can accommodate abundant whispering gallery modes (WGMs) with the mode number increasing with the dimensional sizes of the microresonator. Removing the unnecessary modes while reorganizing the remaining modes is of vital importance, which, however, has been proved challenging and usually results in a tradeoff with the Q of the microresonator. Here, we reveal an effective and controllable mode trimming and clustering mechanism underlying the generation of polygon and star modes in weakly perturbed tapered fiber-coupled lithium niobate whispering gallery microresonators. Experimentally, various polygon and star modes are observed in sequence within a single microresonator by tuning the excitation wavelength or varying the coupling position between a tapered fiber and the circular microresonator, which can be well reproduced with our theoretical model. The finding offers a ubiquitous solution for a broad range of applications requiring elaborate selection and organization of the high-Q WGMs.
- Published
- 2022
12. Electro-optically tunable low phase-noise microwave synthesizer in an active lithium niobate microdisk
- Author
-
Gao, Renhong, Fu, Botao, Yao, Ni, Guan, Jianglin, Zhang, Haisu, Lin, Jintian, Li, Chuntao, Wang, Min, Qiao, Lingling, and Cheng, Ya
- Subjects
Physics - Optics ,Physics - Applied Physics - Abstract
Photonic-based low-phase-noise microwave generation with real-time frequency tuning is crucial for a broad spectrum of subjects, including next-generation wireless communications, radar, metrology, and modern instrumentation. Here, for the first time to the best of our knowledge, narrow-bandwidth dual-wavelength microlasers are generated from nearly degenerate polygon modes in a high-Q active lithium niobate microdisk. The high-Q polygon modes formation with independently controllable resonant wavelengths and free spectral ranges is enabled by the weak perturbation of the whispering gallery microdisk resonators using a tapered fiber. The stable beating signal confirms the low phase-noise achieved in the tunable laser. Owing to the high spatial overlap factors between the two nearly degenerate lasing modes as well as that between the two lasing modes and the pump mode, gain competition between the two modes is suppressed, leading to stable dual-wavelength laser generation and in turn the low noise microwave source. The measured microwave signal shows a linewidth of ~6.87 kHz, a phase noise of ~-123 dBc/Hz, and an electro-optic tuning efficiency of -1.66 MHz/V., Comment: 13 pages, 5 figures
- Published
- 2022
13. Analysis of Rhesus (Rh) Antigen Distributions in Donors and Multi-transfused Patients for Phenotype-Matched Transfusion
- Author
-
Zhao, Yuhong, Yao, Ni, Lv, Yan, Cui, Dawei, and Xie, Jue
- Published
- 2024
- Full Text
- View/download PDF
14. Composite picosecond control of atomic state through a nanofiber interface
- Author
-
Ma, Yudi, Liu, Ruijuan, Ji, Lingjing, Qiu, Liyang, Wu, Saijun, Su, Dianqiang, Zhao, Yanting, Yao, Ni, and Fang, Wei
- Subjects
Physics - Optics ,Physics - Atomic Physics ,Quantum Physics - Abstract
Atoms are ideal quantum sensors and quantum light emitters. Interfacing atoms with nanophotonic devices promises novel nanoscale sensing and quantum optical functionalities. But precise optical control of atomic states in these devices is challenged by the spatially varying light-atom coupling strength, generic to nanophotonic. We demonstrate numerically that despite the inhomogenuity, composite picosecond optical pulses with optimally tailored phases are able to evanescently control the atomic electric dipole transitions nearly perfectly, with $f>99\%$ fidelity across large enough volumes for {\it e.g.} controlling cold atoms confined in near-field optical lattices. Our proposal is followed by a proof-of-principle demonstration with a $^{85}$Rb vapor -- optical nanofiber interface, where the excitation by an $N=3$ sequence of guided picosecond D1 control reduces the absorption of a co-guided nanosecond D2 probe by up to $\sim70\%$. The close-to-ideal performance is corroborated by comparing the absorption data across the parameter space with first-principle modeling of the mesoscopic atomic vapor response. Extension of the composite technique to $N\geq 5$ appears highly feasible to support arbitrary local control of atomic dipoles with exquisite precision. This unprecedented ability would allow error-resilient atomic spectroscopy and open up novel nonlinear quantum optical research with atom-nanophotonic interfaces., Comment: 19 pages, 12 figures, substantial revision
- Published
- 2022
15. Factors influencing pre-service special education teachers’ intention toward AI in education: Digital literacy, teacher self-efficacy, perceived ease of use, and perceived usefulness
- Author
-
Yao, Ni and Wang, Qiong
- Published
- 2024
- Full Text
- View/download PDF
16. Model-level attention and batch-instance style normalization for federated learning on medical image segmentation
- Author
-
Zhu, Fubao, Tian, Yanhui, Han, Chuang, Li, Yanting, Nan, Jiaofen, Yao, Ni, and Zhou, Weihua
- Published
- 2024
- Full Text
- View/download PDF
17. Coherent mode-combined ultra-narrow-linewidth single-mode micro-disk laser
- Author
-
Lin, Jintian, Farajollahi, Saeed, Fang, Zhiwei, Yao, Ni, Gao, Renhong, Guan, Jianglin, Deng, Li, Lu, Tao, Wang, Min, Zhang, Haisu, Fang, Wei, Qiao, Lingling, and Cheng, Ya
- Subjects
Physics - Optics - Abstract
Integrated single-mode microlasers with ultra-narrow linewidths play a game-changing role in a broad spectrum of applications ranging from coherent communication and LIDAR to metrology and sensing. Generation of such light sources in a controllable and cost-effective manner remains an outstanding challenge due to the difficulties in the realization of ultra-high Q active micro-resonators with suppressed mode numbers. Here, we report a microlaser generated in an ultra-high Q Erbium doped lithium niobate (LN) micro-disk. Through the formation of coherently combined polygon modes at both pump and laser wavelengths, the microlaser exhibits single mode operation with an ultra-narrow-linewidth of 98 Hz. In combination with the superior electro-optic and nonlinear optical properties of LN crystal, the mass-producible on-chip single-mode microlaser will provide an essential building block for the photonic integrated circuits demanding high precision frequency control and reconfigurability.
- Published
- 2021
18. Lithium niobate microring with ultra-high Q factor above 10^8
- Author
-
Gao, Renhong, Yao, Ni, Guan, Jianglin, Deng, Li, Lin, Jintian, Wang, Min, Qiao, Lingling, Fang, Wei, and Cheng, Ya
- Subjects
Physics - Optics ,Physics - Applied Physics - Abstract
We demonstrate ultra-high Q factor microring resonators close to the intrinsic material absorption limit on lithium niobate on insulator. The microrings are fabricated on pristine lithium niobate (LN) thin film wafer thinned from LN bulk via chemo-mechanical etching without ion slicing and ion etching. A record-high Q factor up to times ten to the power of 8th at the wavelength of 1550 nm is achieved because of the ultra-smooth interface of the microrings and the absence of ion induced lattice damage, indicating an ultra-low waveguide propagation loss of about 0.28 dB per meter. The ultra-high Q microrings will pave the way for integrated quantum light source, frequency comb generation, and nonlinear optical processes., Comment: 6 pages, 3 figures
- Published
- 2021
19. On-chip ultra-narrow-linewidth single-mode microlaser on lithium niobate on insulator
- Author
-
Gao, Renhong, Guan, Jianglin, Yao, Ni, Deng, Li, Lin, Jintian, Wang, Min, Qiao, Lingling, Wang, Zhenhua, Liang, Youting, Zhou, Yuan, and Cheng, Ya
- Subjects
Physics - Optics - Abstract
We report an on-chip single mode microlaser with low-threshold fabricated on Erbium doped lithium niobate on insulator (LNOI). The single mode laser emission at 1550.5 nm wavelength is generated in a coupled photonic molecule, which is facilitated by Vernier effect when pumping the photonic molecule at 970 nm. A threshold pump power as low as 200 uW is demonstrated thanks to the high quality factor above 10^6. Moreover, the linewidth of the microlaser reaches 4 kHz, which is the best result in LNOI microlasers. Such single mode micro-laser lithographically fabricated on chip is highly in demand by photonic community.
- Published
- 2021
- Full Text
- View/download PDF
20. Broadband highly efficient nonlinear optical processes in on-chip integrated lithium niobate microdisk resonators of Q-factor above 10^8
- Author
-
Gao, Renhong, Zhang, Haisu, Bo, Fang, Fang, Wei, Hao, Zhenzhong, Yao, Ni, Lin, Jintian, Guan, Jianglin, Deng, Li, Wang, Min, Qiao, Lingling, and Cheng, Ya
- Subjects
Physics - Optics - Abstract
We demonstrated broadband highly efficient optical nonlinear processes in on-chip integrated lithium niobate (LN) microdisk resonators. The Q factors of the micro-resonators fabricated by femtosecond laser writing and chemo-mechanical polishing are reliably above 10^8, approaching the intrinsic material absorption limit of LN. Broadband nonlinear processes, including optical parametric oscillation (OPO), second harmonic generation (SHG), third harmonic generation, and fourth harmonic generation, were observed with ultrahigh efficiencies in the same LN microdisk without introducing domain inversion, thanks to the natural quasi phase-matching and the dense spectral modes of the X-cut LN microdisk with millimeter diameter. The threshold of OPO and the absolute conversion efficiency of SHG are 19.6 microwatt and 66%, both surpass the state-of-the-art values among on-chip LN micro-resonators demonstrated so far. The broadband and highly efficient nonlinear frequency conversions achieved with the ultrahigh-Q LN microdisk resonators promise high-density integration of nonlinear photonic devices such as frequency convertors and entangled photon sources., Comment: 27 pages, 9 figures
- Published
- 2021
- Full Text
- View/download PDF
21. Efficient light coupling between an ultra-low loss lithium niobate waveguide and an adiabatically tapered single mode optical fiber
- Author
-
Yao, Ni, Zhou, Junxia, Gao, Renhong, Lin, Jintian, Wang, Min, Cheng, Ya, Fang, Wei, and Tong, Limin
- Subjects
Physics - Optics ,Physics - Applied Physics - Abstract
A lithium niobate on insulator ridge waveguide allows constructing high-density photonic integrated circuits thanks to its small bending radius offered by the high index contrast. Meanwhile, the significant mode-field mismatch between an optical fiber and the single-mode lithium niobate waveguide leads to low coupling efficiencies. Here, we demonstrate, both numerically and experimentally, that the problem can be solved with a tapered single mode fiber of an optimized mode field profile. Numerical simulation shows that the minimum coupling losses for the TE and TM mode are 0.32 dB and 0.86 dB, respectively. Experimentally, though without anti-reflection coating, the measured coupling losses for TE and TM mode are 1.32 dB and 1.88 dB, respectively. Our technique paves a way for a broad range of on-chip lithium niobate applications., Comment: 8 pages, 5 figures
- Published
- 2020
- Full Text
- View/download PDF
22. Mammalian-brain-inspired neuromorphic motion-cognition nerve achieves cross-modal perceptual enhancement
- Author
-
Chengpeng Jiang, Jiaqi Liu, Yao Ni, Shangda Qu, Lu Liu, Yue Li, Lu Yang, and Wentao Xu
- Subjects
Science - Abstract
Inspired by the multisensory cue integration in macaque’s brain for spatial perception, the authors develop a neuromorphic motion-cognition nerve that achieves cross-modal perceptual enhancement for robotics and wearable applications.
- Published
- 2023
- Full Text
- View/download PDF
23. Methylhydroxylase encoded by mchAB gene is involved in methyl oxidation of m-cresol via Comamonas thiooxydans CHJ601
- Author
-
Yao, Ni-Hong, Liu, Xi, Luo, Chenyang, Zou, Lei, Li, Jinhua, Chen, Jing, Yan, Dazhong, and Chao, Hong-Jun
- Published
- 2023
- Full Text
- View/download PDF
24. Microbial detoxification of 3,5-xylenol via a novel process with sequential methyl oxidation by Rhodococcus sp. CHJ602
- Author
-
Yao, Ni-Hong, Du, Ya-Nan, Xiong, Jia-Xi, Xiao, Ying, He, Hang-Hang, Xie, Ze-Feng, Huang, Duo, Song, Qi, Chen, Jing, Yan, Dazhong, and Chao, Hong-Jun
- Published
- 2023
- Full Text
- View/download PDF
25. Enhancement of the Monolayer WS2 Exciton Photoluminescence with a 2D-Material/Air/GaP In-Plane Microcavity
- Author
-
Mey, Oliver, Wall, Franziska, Schneider, Lorenz Maximilian, Günder, Darius, Walla, Frederik, Soltani, Amin, Roskos, Hartmut G., Yao, Ni, Qing, Peng, Fang, Wei, and Rahimi-Iman, Arash
- Subjects
Physics - Applied Physics ,Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
Light-matter interaction with two-dimensional materials gained significant attention in recent years leading to the reporting of weak and strong coupling regimes, and effective nano-laser operation with various structures. Particularly, future applications involving monolayer materials in waveguide-coupled on-chip integrated circuitry and valleytronic nanophotonics require controlling, directing and optimizing photoluminescence. In this context, photoluminescence enhancement from monolayer transition-metal dichalcogenides on patterned semiconducting substrates becomes attractive. It is demonstrated in our work using focussed-ion-beam-etched GaP and monolayer WS2 suspended on hexagonal-BN buffer sheets. We present a unique optical microcavity approach capable of both efficient in-plane and out-of-plane confinement of light, which results in a WS2 photoluminescence enhancement by a factor of 10 compared to the unstructured substrate at room temperature. The key concept is the combination of interference effects in both the horizontal direction using a bull's-eye-shaped circular Bragg grating and in vertical direction by means of a multiple reflection model with optimized etch depth of circular air-GaP structures for maximum constructive interference effects of the applied pump and expected emission light.
- Published
- 2018
26. Ultrasensitive hybrid optical skin
- Author
-
Zhang, Lei, Pan, Jing, Zhang, Zhang, Wu, Hao, Yao, Ni, Cai, Dawei, Xu, Yingxin, Zhang, Jin, Sun, Guofei, Wang, Liqiang, Geng, Weidong, Jin, Wenguang, Fang, Wei, Di, Dawei, and Tong, Limin
- Subjects
Physics - Applied Physics ,Physics - Optics - Abstract
Electronic skin, a class of wearable electronic sensors that mimic the functionalities of human skin, has made remarkable success in applications including health monitoring, human-machine interaction and electronic-biological interfaces. While electronic skin continues to achieve higher sensitivity and faster response, its ultimate performance is fundamentally limited by the nature of low-frequency AC currents in electronic circuitries. Here we demonstrate highly sensitive optical skin (O-skin) in which the primary sensory elements are optically driven. The simple construction of the sensors is achieved by embedding glass micro/nanofibers (MNFs) in thin layers of polydimethylsiloxane (PDMS). Enabled by the highly sensitive power-leakage response of the guided modes from the MNF upon external stimuli, our optical sensors show ultrahigh sensitivity (1870/kPa), low detection limit (7 mPa) and fast response (10 microseconds) for pressure sensing, significantly exceeding the performance metrics of state-of-the-art electronic skins. Electromagnetic interference (EMI)-free detection of high-frequency vibrations, wrist pulse and human voice are realized. Moreover, a five-sensor optical data glove and a 2x2-MNF tactile sensor are demonstrated. Our results pave the way toward wearable optical devices ranging from ultrasensitive flexible sensors to optical skins.
- Published
- 2018
27. Lithium niobate micro-disk resonators of quality factors above 10^7
- Author
-
Wu, Rongbo, Zhang, Jianhao, Yao, Ni, Fang, Wei, Qiao, Lingling, Chai, Zhifang, Lin, Jintian, and Cheng, Ya
- Subjects
Physics - Applied Physics ,Physics - Optics - Abstract
We report on fabrication of crystalline lithium niobate microresonators with quality factors above 10^7 as measured around 770 nm wavelength. Our technique relies on femtosecond laser micromachining for patterning a mask coated on the lithium niobate on insulate (LNOI) into a microdisk, followed by a chemo-mechanical polishing process for transferring the disk-shaped pattern to the LNOI. Nonlinear processes including second harmonic generation and Raman scattering have been demonstrated in the fabricated microdisk., Comment: 3 pages, 4 figures
- Published
- 2018
- Full Text
- View/download PDF
28. Simultaneous generation of four-wave mixing and stimulated Raman scattering in coupled lithium niobate microdisks mediated by second harmonic generation
- Author
-
Wang, Min, Yao, Ni, Wu, Rongbo, Fang, Zhiwei, Lv, Shilong, Zhang, Jianhao, Qiao, Lingling, Lin, Jintian, Fang, Wei, and Cheng, Ya
- Subjects
Physics - Optics - Abstract
High quality lithium niobate thin film microresonators provide an ideal platform for on-chip nonlinear optics applications. However, the phase matching condition for efficient parametric process sets a high requirement for fabrication control. Here we demonstrate a photonic molecular structure composed of two strongly coupled lithium niobate microdisks of different diameters fabricated using femtosecond laser micromachining and focused ion beam milling. With a continuous wave excitation, rich nonlinear optical processes including cascaded four-wave mixing and stimulated Raman scattering were observed around the second harmonic wavelength. Our results indicate that the coupled microdisks form a superior system for nonlinear optical process., Comment: 17 pages, 4 figures
- Published
- 2018
29. Fabrication of high quality factor lithium niobate double-disk using a femtosecond laser
- Author
-
Fang, Zhiwei, Yao, Ni, Wang, Min, Lin, Jintian, Zhang, Jianhao, Wu, Rongbo, Qiao, Lingling, Fang, Wei, Lu, Tao, and Cheng, Ya
- Subjects
Physics - Applied Physics ,Physics - Optics - Abstract
We demonstrate fabrication of a high quality factor lithium niobate double-disk whispering-gallery microcavity using femtosecond laser assisted ion beam milling. Using this method, two vertically stacked 30-um-diameter disks with a 200-nm-gap are fabricated. With our device, an optical quality factor as high as 1.2*10^5 is demonstrated. Our approach is scalable to fabricate multiple disks on a single chip., Comment: 17 pages, 4 figures
- Published
- 2017
30. Flexible optoelectronic neural transistors with broadband spectrum sensing and instant electrical processing for multimodal neuromorphic computing
- Author
-
Yao Ni, Lu Yang, Jiulong Feng, Jiaqi Liu, Lin Sun, and Wentao Xu
- Subjects
flexible optoelectronic neural transistor ,high‐pass filtering ,Morse‐code recognition system ,sensitive image reconstruction and multitarget monitoring ,spatiotemporally correlated coding and logic function ,Materials of engineering and construction. Mechanics of materials ,TA401-492 - Abstract
Abstract A flexible optoelectronic neural transistor (OENT) that consists of a one‐step spin‐coated tri‐blend film composed of 2,7‐dioctyl[1]benzothieno[3,2‐b][1]benzothiophene (C8‐BTBT), poly(3‐hexylthiophene‐2,5‐diyl) (P3HT), and poly(methyl methacrylate) (PMMA) is demonstrated. The C8‐BTBT and P3HT phases in the film partially segregate into distinct domains, which combine to provide broadband spectrum sensing, and instant electrical‐processing capabilities dominated by C8‐BTBT. The OENT is sensitive to solar radiation from the near‐ultraviolet (NUV) and to visible (Vis) radiation from blue to red. When exposed to NUV radiation, the OENT responds sensitively and retains the memory of the exposure for over 103 s. The OENT provides a warning of excessive chronic exposure to harmful NUV. These properties allow high‐pass filtering with different cut‐off frequencies fc that can restrict the reception of blue, green, or red. These switchable fc enables sensitive image reconstruction and multitarget monitoring. The device combined with a chitosan gel achieves strictly defined short‐range plasticity of
- Published
- 2023
- Full Text
- View/download PDF
31. CRISPR/Cas9-mediated genome editing in vancomycin-producing strain Amycolatopsis keratiniphila
- Author
-
Mengyi Hu, Shuo Chen, Yao Ni, Wei Wei, Wenwei Mao, Mei Ge, and Xiuping Qian
- Subjects
amycolatopsis ,CRISPR/Cas9 ,genome editing ,large fragment deletion ,Eco-0501 ,vancomycin ,Biotechnology ,TP248.13-248.65 - Abstract
Amycolatopsis is an important source of diverse valuable bioactive natural products. The CRISPR/Cas-mediated gene editing tool has been established in some Amycolatopsis species and has accomplished the deletion of single gene or two genes. The goal of this study was to develop a high-efficient CRISPR/Cas9-mediated genome editing system in vancomycin-producing strain A. keratiniphila HCCB10007 and enhance the production of vancomycin by deleting the large fragments of ECO-0501 BGC. By adopting the promoters of gapdhp and ermE*p which drove the expressions of scocas9 and sgRNA, respectively, the all-in-one editing plasmid by homology-directed repair (HDR) precisely deleted the single gene gtfD and inserted the gene eGFP with the efficiency of 100%. Furthermore, The CRISPR/Cas9-mediated editing system successfully deleted the large fragments of cds13-17 (7.7 kb), cds23 (12.7 kb) and cds22-23 (21.2 kb) in ECO-0501 biosynthetic gene cluster (BGC) with high efficiencies of 81%–97% by selecting the sgRNAs with a suitable PAM sequence. Finally, a larger fragment of cds4-27 (87.5 kb) in ECO-0501 BGC was deleted by a dual-sgRNA strategy. The deletion of the ECO-0501 BGCs revealed a noticeable improvement of vancomycin production, and the mutants, which were deleted the ECO-0501 BGCs of cds13-17, cds22-23 and cds4-27, all achieved a 30%–40% increase in vancomycin yield. Therefore, the successful construction of the CRISPR/Cas9-mediated genome editing system and its application in large fragment deletion in A. keratiniphila HCCB10007 might provide a powerful tool for other Amycolatopsis species.
- Published
- 2023
- Full Text
- View/download PDF
32. Optical fibre taper-enabled waveguide photoactuators
- Author
-
Xiao, Jianliang, Zhou, Tao, Yao, Ni, Ma, Shuqi, Pan, Chenxinyu, Wang, Pan, Fu, Haoran, Liu, Haitao, Pan, Jing, Yu, Longteng, Wang, Shipeng, Yang, Wenzhen, Tong, Limin, and Zhang, Lei
- Published
- 2022
- Full Text
- View/download PDF
33. Multiplexed neurochemical transmission emulated using a dual-excitatory synaptic transistor
- Author
-
Mingxue Ma, Yao Ni, Zirong Chi, Wanqing Meng, Haiyang Yu, Jiangdong Gong, Huanhuan Wei, Hong Han, Xinran Wang, and Wentao Xu
- Subjects
Materials of engineering and construction. Mechanics of materials ,TA401-492 ,Chemistry ,QD1-999 - Abstract
Abstract The ability to emulate multiplexed neurochemical transmission is an important step toward mimicking complex brain activities. Glutamate and dopamine are neurotransmitters that regulate thinking and impulse signals independently or synergistically. However, emulation of such simultaneous neurotransmission is still challenging. Here we report design and fabrication of synaptic transistor that emulates multiplexed neurochemical transmission of glutamate and dopamine. The device can perform glutamate-induced long-term potentiation, dopamine-induced short-term potentiation, or co-release-induced depression under particular stimulus patterns. More importantly, a balanced ternary system that uses our ambipolar synaptic device backtrack input ‘true’, ‘false’ and ‘unknown’ logic signals; this process is more similar to the information processing in human brains than a traditional binary neural network. This work provides new insight for neuromorphic systems to establish new principles to reproduce the complexity of a mammalian central nervous system from simple basic units.
- Published
- 2021
- Full Text
- View/download PDF
34. Mimicking efferent nerves using a graphdiyne-based artificial synapse with multiple ion diffusion dynamics
- Author
-
Huanhuan Wei, Rongchao Shi, Lin Sun, Haiyang Yu, Jiangdong Gong, Chao Liu, Zhipeng Xu, Yao Ni, Jialiang Xu, and Wentao Xu
- Subjects
Science - Abstract
Constructing artificial sensorimotor systems for robotic applications calls for development of synaptic connections for complicated information processing. Wei et al. propose a graphdiyne-based artificial synapse capable of parallel processing signals and utilize it in an artificial mechanoreceptor system.
- Published
- 2021
- Full Text
- View/download PDF
35. Coding and non-coding RNA interactions reveal immune-related pathways in peripheral blood mononuclear cells derived from patients with proliferative vitreoretinopathy
- Author
-
Yao Ni, Fangyuan Liu, Xiao Hu, Yingyan Qin, and Zhaotian Zhang
- Subjects
Proliferative vitreoretinopathy ,Gene expression profile ,Long non-coding RNAs ,Immune-related pathway ,Internal medicine ,RC31-1245 ,Genetics ,QH426-470 - Abstract
Abstract Background Peripheral immune response has been revealed to play a critical role in proliferative vitreoretinopathy (PVR). However, the reliable immune-related factors that are acting as prognostic indicators or therapeutic targets for PVR remain to explore further. Methods In the current study, we applied whole-transcriptome sequencing to profile peripheral blood mononuclear cells from PVR patients and also analyzed lncRNA-mRNA interactions in peripheral immune cells to explore the pathways that might mediate immunopathology and resultant retinal damage in PVR. Gene ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses and Ingenuity Pathway Analysis (IPA) were employed to classify the function of these differentially expressed genes. Results Compared to the controls, there were 319 genes upregulated, and 191 genes downregulated in PVR patients. GO, and KEGG enrichment analyses as well as IPA showed that these upregulated genes were significantly enriched in immune-related and infection-relate terms. Immune-related gene NFKBIA, CXCL2, and CXCL8 were detected as hub-genes in the co-expression network, while lncRNAs such as AC007032.1, AC037198.2, AL929472.2, and SLED1 were highly co-expressed with them. lncRNA-mRNA interactions analysis also showed that putative targeted genes of these differentially expressed lncRNAs were also significantly enriched in immune-related or infection-relate pathways. Conclusion Our study highlights the transformation of immune-related genes/pathways in PVR by comparing controls, and validates several critical genes and lncRNAs, which are serving as potential diagnostic markers for PVR patients.
- Published
- 2021
- Full Text
- View/download PDF
36. An Artificial Nerve Capable of UV‐Perception, NIR–Vis Switchable Plasticity Modulation, and Motion State Monitoring
- Author
-
Yao Ni, Jiulong Feng, Jiaqi Liu, Hang Yu, Huanhuan Wei, Yi Du, Lu Liu, Lin Sun, Jianlin Zhou, and Wentao Xu
- Subjects
artificial neural network ,broadband light ,flexible organic‐heterojunction neuromorphic transistors ,motion state monitoring ,multiplexed‐neurotransmission signals ,Science - Abstract
Abstract The first flexible organic‐heterojunction neuromorphic transistor (OHNT) that senses broadband light, including near‐ultraviolet (NUV), visible (vis), and near‐infrared (NIR), and processes multiplexed‐neurotransmission signals is demonstrated. For UV perception, electrical energy consumption down to 536 aJ per synaptic event is demonstrated, at least one order of magnitude lower than current UV‐sensitive synaptic devices. For NIR‐ and vis‐perception, switchable plasticity by alternating light sources is yielded for recognition and memory. The device emulates multiplexed neurochemical transition of different neurotransmitters such as dopamine and noradrenaline to form short‐term and long‐term responses. These facilitate the first realization of human‐integrated motion state monitoring and processing using a synaptic hardware, which is then used for real‐time heart monitoring of human movement. Motion state analysis with the 96% accuracy is then achieved by artificial neural network. This work provides important support to future biomedical electronics and neural prostheses.
- Published
- 2022
- Full Text
- View/download PDF
37. The influence of adolescents’ internet adaptation on internet addiction: the mediating role of internet cultural adaptation
- Author
-
Yue, Yang, primary, Jun, Zhan, additional, Yao, Ni, additional, Yanwen, Fan, additional, Yiting, Zhang, additional, and Yiting, Fang, additional
- Published
- 2024
- Full Text
- View/download PDF
38. Ameliorating Effects of Aloe Emodin in an Aluminum‐Induced Alzheimer's Disease Rat Model.
- Author
-
Zhao, Xitong, Yao, Ni, Fan, Wenqian, Du, Baojian, Chen, Yang, Wang, Chuyin, Song, Lingling, Yin, Jianing, Fang, Fang, Guan, Jun, and Verma, Akhilesh K.
- Subjects
- *
LABORATORY rats , *ALZHEIMER'S disease , *OLDER people , *CHOLINERGIC mechanisms , *ALUMINUM chloride - Abstract
Alzheimer's disease (AD) is a neurodegenerative disease and threatens the health of the aged population worldwide. In the present study, we investigated cognitive improvement by aloe emodin in aluminum‐induced AD rats. We orally administered aluminum chloride (150 mg/kg) to Sprague–Dawley rats for 8 weeks to induce AD. In the 5th to the 8th week, the rats were injected intraperitoneally with AE (5, 10, and 15 mg/kg). Behavioral, histopathological, and biochemical assessments were performed. The results showed that AE alleviated cognitive impairment in aluminum‐induced AD rats and inhibited aluminum‐induced hippocampal neuronal damage. Furthermore, aloe emodin relieved the aluminum burden in the brain of aluminum‐induced AD rats, attenuated the aluminum‐induced increase in Aβ42 level and acetylcholinesterase activity, and reduced the levels of tumor necrosis factor‐α, interleukin‐6, interleukin‐1α, and interleukin‐1β. These effects suggest that the mechanism by which AE alleviates AD‐related cognitive impairment is by removal of excess aluminum, decreasing Aβ42 deposition, regulating the cholinergic system, and reducing neuroinflammation. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
39. Body mass index, smoking behavior, and depression mediated the effects of schizophrenia on chronic obstructive pulmonary disease: trans-ethnic Mendelian-randomization analysis.
- Author
-
Yao Ni, DaWei Zhang, Wenlong Tang, Liming Xiang, Xiaoding Cheng, Youqian Zhang, and Yanyan Feng
- Subjects
CHRONIC obstructive pulmonary disease ,BODY mass index ,FALSE discovery rate ,SMOKING ,MENTAL depression ,SCHIZOAFFECTIVE disorders - Abstract
Background: Previous studies have highlighted the association between schizophrenia (SCZ) and chronic obstructive pulmonary disease (COPD), yet the causal relationship remains unestablished. Methods: Under the genome-wide significance threshold (P<5x10
-8 ), data from individuals of European (EUR) and East Asian (EAS) ancestries with SCZ were selected for analysis. Univariable Mendelian randomization (MR) explored the causal relationship between SCZ and COPD. Linkage disequilibrium score (LDSC) regression was used to calculate genetic correlation, while multivariable and mediation MR further investigated the roles of six confounding factors and their mediating effects. The primary method utilized was inverse-variance weighted (IVW), complemented by a series of sensitivity analyses and false discovery rate (FDR) correction. Results: LDSC analysis revealed a significant genetic correlation between SCZ and COPD within EUR ancestry (rg = 0.141, P = 6.16x10-7 ), with no such correlation found in EAS ancestry. IVW indicated a significant causal relationship between SCZ and COPD in EUR ancestry (OR = 1.042, 95% CI 1.013-1.071, P = 0.003, PFDR = 0.015). Additionally, replication datasets provide evidence of consistent causal associations(P < 0.05 & PFDR < 0.05). Multivariable and mediation MR analyses identified body mass index (BMI)(Mediation effect: 50.57%, P = 0.02), age of smoking initiation (Mediation effect: 27.42%, P = 0.02), and major depressive disorder (MDD) (Mediation effect: 60.45%, P = 6.98x10-5 ) as partial mediators of this causal relationship. No causal associations were observed in EAS (OR = 0.971, 95% CI 0.875-1.073, P = 0.57; PFDR = 0.761) ancestry. No causal associations were found in the reverse analysis across the four ancestries (P > 0.05 & PFDR > 0.05). Conclusions: This study confirmed a causal relationship between SCZ and the risk of COPD in EUR ancestry, with BMI, smoking, and MDD serving as key mediators. Future research on a larger scale is necessary to validate the generalizability of these findings across other ancestries. [ABSTRACT FROM AUTHOR]- Published
- 2024
- Full Text
- View/download PDF
40. Flexible Electronics and Healthcare Applications
- Author
-
Zixian Wang, Lin Sun, Yao Ni, Lu Liu, and Wentao Xu
- Subjects
flexible electronics ,structural design ,flexible material ,stretchability ,medical applications ,Chemical technology ,TP1-1185 - Abstract
Flexible electronics has attracted tremendous attention in recent years. The essential requirements for flexible electronics include excellent electrical properties, flexibility and stretchability. By introducing special structures or using flexible materials, electronic devices can be given excellent flexibility and stretchability. In this paper we review the realization of flexible electronics from the perspective of structural design strategies and materials; then, healthcare application of flexible electronic systems was introduced. Finally, a brief summary and outlook are presented.
- Published
- 2021
- Full Text
- View/download PDF
41. Identification of Structural Features for the Inhibition of OAT3-Mediated Uptake of Enalaprilat by Selected Drugs and Flavonoids
- Author
-
Yao Ni, Zelin Duan, Dandan Zhou, Shuai Liu, Huida Wan, Chunshan Gui, and Hongjian Zhang
- Subjects
three-dimensional quantitative structure-activity relationship ,enalaprilat ,flavonoid ,herb-drug interaction ,organic anion transporter 3 (OAT3) ,Therapeutics. Pharmacology ,RM1-950 - Abstract
Enalaprilat is the active metabolite of enalapril, a widely used antihypertension drug. The human organic anion transporter 3 (OAT3), which is highly expressed in the kidney, plays a critical role in the renal clearance of many drugs. While urinary excretion is the primary elimination route of enalaprilat, direct involvement of OAT3 has not been reported so far. In the present study, OAT3-mediated uptake of enalaprilat was first characterized, and the inhibition of OAT3 transport activity was then examined for a number of flavonoid and drug molecules with diverse structures. A varying degree of inhibition potency was demonstrated for flavonoids, with IC50 values ranging from 0.03 to 22.6 µM against OAT3 transport activity. In addition, commonly used drugs such as urate transporter 1 (URAT1) inhibitors also displayed potent inhibition on OAT3-mediated enalaprilat uptake. Pharmacophore and three-dimensional quantitative structure-activity relationship (3D-QSAR) analyses revealed the presence of a polar center and a hydrophobic region involved in OAT3-inhibitor binding. For the polar center, hydroxyl groups present in flavonoids could act as either hydrogen bond donors or acceptors and the number and position of hydroxyl groups were critical drivers for inhibition potency, while carboxyl groups present in some drugs could form ionic bridges with OAT3. The predicted inhibition potencies by comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) were correlated well with experimental IC50 values. Taken together, the present study identified OAT3-mediated uptake of enalaprilat as an important mechanism for its renal clearance, which may be liable for drug-drug and herb-drug interactions. The established computational models revealed unique structural features for OAT3 inhibitors and could be used for structure-activity relationship (SAR) analysis of OAT3 inhibition. The clinical relevance of the inhibition of OAT3-mediated enalaprilat uptake warrants further investigation, particularly in populations where herbal remedies and drugs are used concomitantly.
- Published
- 2020
- Full Text
- View/download PDF
42. Multi-Node All-Optical Interconnect Network Routing for Data-Center Parallel Computers
- Author
-
Shuailong Yang, Liu Yang, Fengguang Luo, Biyu You, Yao Ni, and Danhui Chen
- Subjects
Optical interconnection ,waveguide and optical communications ,field programmable gate array ,electro-optic printed circuit board. ,Applied optics. Photonics ,TA1501-1820 ,Optics. Light ,QC350-467 - Abstract
A multi-node all-optical interconnect network-routing architecture scheme and implementation technology are designed to improve high-speed and large-capacity data transmission in data centers. In the design of the optical interconnect routing electro-optic printed circuit board (EOPCB), the signal generated by the FPGA is directly modulated by the VCSEL arrays, and through the coupler into the parallel optical waveguide. The transmission link and optical switch are operated in optical domain. The designed optical waveguide comprises 12 waveguide arrays with the space of 250 μm. The all-optical interconnection routing system, which is based on the EOPCB high-speed chip multi-node waveguide, is designed, and a 4 × 4 EOPCB is fabricated. The performance of the waveguide and the entire optical interconnection network is tested. Based on 10 Gb/s VCSEL arrays, the optical interconnect network system can reach a bandwidth of 640 GHz for 4 × 4 networks. The best bit error rate for the switching system can reach 9.0 × 10-12 with no transmission error.
- Published
- 2019
- Full Text
- View/download PDF
43. Tunable Synaptic Plasticity in Crystallized Conjugated Polymer Nanowire Artificial Synapses
- Author
-
Hong Han, Zhipeng Xu, Kexin Guo, Yao Ni, Mingxue Ma, Haiyang Yu, Huanhuan Wei, Jiangdong Gong, Shuo Zhang, and Wentao Xu
- Subjects
conjugated polymers ,nanowires ,synaptic plasticity ,neuromorphic devices ,synaptic transistors ,Computer engineering. Computer hardware ,TK7885-7895 ,Control engineering systems. Automatic machinery (General) ,TJ212-225 - Abstract
In biological synapses, short‐term plasticity is important for computation and signal transmission, whereas long‐term plasticity is essential for memory formation. Comparably, designing a strategy that can easily tune the synaptic plasticity of artificial synapses can benefit constructing an artificial neural system, where synapses with different short‐term plasticity (STP) and long‐term plasticity (LTP) are required. Herein, a strategy is designed that can easily tune the plasticity of crystallized conjugated polymer nanowire‐based synaptic transistors (STs) by low‐temperature solvent engineering. Essential synaptic functions are achieved, such as excitatory postsynaptic current (EPSC), paired‐pulse facilitation (PPF), spike‐frequency‐dependent plasticity (SFDP), spike‐duration‐dependent plasticity (SDDP) and spike‐number‐dependent plasticity (SNDP), and potentiation/depression. The balance between crystallinity and roughness is successfully adjusted by altering solvent compositions, and plasticity of the synaptic device is easily tuned between short term and long term. The evident transition from STP to LTP, good linearity and symmetry of potentiation and depression, and the broad dynamic working range of synaptic weight are achieved. This provides a facile way to tune synaptic plasticity at low temperatures and is applicable to future organic and flexible artificial nervous systems.
- Published
- 2020
- Full Text
- View/download PDF
44. Ultrasensitive skin-like wearable optical sensors based on glass micro/nanofibers
- Author
-
Zhang Lei, Pan Jing, Zhang Zhang, Wu Hao, Yao Ni, Cai Dawei, Xu Yingxin, Zhang Jin, Sun Guofei, Wang Liqiang, Geng Weidong, Jin Wenguang, Fang Wei, Di Dawei, and Tong Limin
- Subjects
optical micro/nanofiber ,pressure sensor ,tactile sensor ,wearable sensor ,Optics. Light ,QC350-467 - Abstract
Electronic skin, a class of wearable electronic sensors that mimic the functionalities of human skin, has made remarkable success in applications including health monitoring, human-machine interaction and electronic-biological interfaces. While electronic skin continues to achieve higher sensitivity and faster response, its ultimate performance is fundamentally limited by the nature of low-frequency AC currents. Herein, highly sensitive skin-like wearable optical sensors are demonstrated by embedding glass micro/nanofibers (MNFs) in thin layers of polydimethylsiloxane (PDMS). Enabled by the transition from guided modes into radiation modes of the waveguiding MNFs upon external stimuli, the skin-like optical sensors show ultrahigh sensitivity (1870 kPa-1), low detection limit (7 mPa) and fast response (10 μs) for pressure sensing, significantly exceeding the performance metrics of state-of-the-art electronic skins. Electromagnetic interference (EMI)-free detection of high-frequency vibrations, wrist pulse and human voice are realized. Moreover, a five-sensor optical data glove and a 2×2-MNF tactile sensor are demonstrated. These initial results pave the way toward a new category of optical devices ranging from ultrasensitive wearable sensors to optical skins.
- Published
- 2020
- Full Text
- View/download PDF
45. Visualized in-sensor computing.
- Author
-
Yao Ni, Jiaqi Liu, Hong Han, Qianbo Yu, Lu Yang, Zhipeng Xu, Chengpeng Jiang, Lu Liu, and Wentao Xu
- Abstract
In artificial nervous systems, conductivity changes indicate synaptic weight updates, but they provide limited information compared to living organisms. We present the pioneering design and production of an electrochromic neuromorphic transistor employing color updates to represent synaptic weight for in-sensor computing. Here, we engineer a specialized mechanism for adaptively regulating ion doping through an ion-exchange membrane, enabling precise control over color-coded synaptic weight, an unprecedented achievement. The electrochromic neuromorphic transistor not only enhances electrochromatic capabilities for hardware coding but also establishes a visualized pattern-recognition network. Integrating the electrochromic neuromorphic transistor with an artificial whisker, we simulate a bionic reflex system inspired by the longicorn beetle, achieving real-time visualization of signal flow within the reflex arc in response to environmental stimuli. This research holds promise in extending the biomimetic coding paradigm and advancing the development of bio-hybrid interfaces, particularly in incorporating color-based expressions. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
46. Commentary: Causal relationship between particulate matter 2.5 and diabetes: two sample Mendelian randomization.
- Author
-
Yao Ni, Youqian Zhang, Jianzhou Ye, and Xuesong Yang
- Published
- 2024
- Full Text
- View/download PDF
47. A neuromorphic device mimicking synaptic plasticity under different body fluid K+ homeostasis for artificial reflex path construction and pattern recognition.
- Author
-
Lu Yang, Yao Ni, Chengpeng Jiang, Lu Liu, Song Zhang, Jiaqi Liu, Lin Sun, and Wentao Xu
- Subjects
- *
BODY fluids , *HUMAN-machine systems , *POTASSIUM ions , *ASSOCIATIVE learning , *ARTIFICIAL neural networks - Abstract
The ionic environment of body fluids influences nervous functions for maintaining homeostasis in organisms and ensures normal perceptual abilities and reflex activities. Neural reflex activities, such as limb movements, are closely associated with potassium ions (K+). In this study, we developed artificial synaptic devices based on ion concentration-adjustable gels for emulating various synaptic plasticities under different K+ concentrations in body fluids. In addition to performing essential synaptic functions, potential applications in information processing and associative learning using short- and long-term plasticity realized using ion concentration-adjustable gels are presented. Artificial synaptic devices can be used for constructing an artificial neural pathway that controls artificial muscle reflex activities and can be used for image pattern recognition. All tests show a strong relationship with ion homeostasis. These devices could be applied to neuromorphic robots and human-machine interfaces. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
48. Analysis of Rhesus (Rh) Antigen Distributions in Donors and Multi-transfused Patients for Phenotype-Matched Transfusion
- Author
-
Zhao, Yuhong, primary, Yao, Ni, additional, Lv, Yan, additional, Cui, Dawei, additional, and Xie, Jue, additional
- Published
- 2023
- Full Text
- View/download PDF
49. The effect of antioxidant dietary supplements and diet-derived circulating antioxidants on vitiligo outcome: evidence from genetic association and comprehensive Mendelian randomization.
- Author
-
Yao Ni, Youqian Zhang, Jingying Sun, Lingyi Zhao, Bo Wu, and Jianzhou Ye
- Published
- 2024
- Full Text
- View/download PDF
50. MDR‐Net: Multiscale dense residual networks for liver image segmentation
- Author
-
Xie, Lijie, primary, Zhu, Fubao, additional, and Yao, Ni, additional
- Published
- 2023
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.