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7. Improvement of Stress Resistance of Microencapsulated Lactobacillus plantarum by Emulsion Electrospinning.

Author

Wu, Yuehan, Zhang, Shanshan, Yan, Ziyou, Li, Shiyang, Wang, Qianwen, and Gao, Zhiming

Subjects
EMULSIONS, LACTOBACILLUS plantarum, LACTOBACILLUS, ELECTROSPINNING, LOCAL delivery services, PROBIOTICS, ALIMENTARY canal, HUMAN ecology
Abstract

Probiotics have become increasingly recognized for their potential health-promoting properties; however, the viability of probiotics can be affected by storage and transportation processes as well as the stressful environment of the human digestive tract, preventing them from achieving effective concentration (107 CFU/mL). In this regard, the embedding technology of probiotics provides an effective protection method. Dextran-based water in water (W/W) emulsion loaded with Lactobacillus plantarum was used as spinning solution to prepare Lactobacillus plantarum-loaded electrospun fibers. The structure of the W/W emulsion and the electrospun fibers was charactered. Lactobacillus plantarum were uniformly embedded in the internal phase of the W/W emulsion and the loading efficiency was 9.70 ± 0.40 log CFU/g. After 240 min digestion in the gastrointestinal tract, and temperature treatment in 65 °C and 72 °C, the loaded probiotics maintained high activity. Even after 5 days of storage in room temperature and 4 °C, the loaded probiotic activity levels remained high, with counts >8 log CFU/g. These results suggest that probiotics encapsulated by emulsion electrospinning could be potentially delivered in a novel food delivery system used in the future food industry. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Pretreatment Serum Lactate Dehydrogenase and Metastases Numbers as Potential Determinants of Anti-PD-1 Therapy Outcome in Nasopharyngeal Carcinoma

Author

Ali, Wael A. S., primary, Huang, Xinxin, additional, Wu, Yuehan, additional, Ma, Yuxiang, additional, Pan, Hui, additional, Liao, Jun, additional, Yang, Zhang, additional, Hong, Shaodong, additional, Yang, Yunpeng, additional, Huang, Yan, additional, Zhao, Yuanyuan, additional, Fang, Wenfeng, additional, Zhao, Hongyun, additional, and Zhang, Li, additional

Published
2023
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12. PARP1 is required for chromosomal translocations

Author

Wray, Justin, Williamson, Elizabeth A., Singh, Sudha B., Wu, Yuehan, Cogle, Christopher R., Weinstock, David M., Zhang, Yu, Lee, Suk-Hee, Zhou, Daohong, Shao, Lijian, Hauer-Jensen, Martin, Pathak, Rupak, Klimek, Virginia, Nickoloff, Jac A., and Hromas, Robert

Published
2013
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13. Composite Oleogels Formed by Cellulose Particles and Sorbitan Acid Esters

Author

Gao, Zhiming, Zhang, Chao, Wu, Yuehan, Chen, Fangfang, Hu, Bing, Wang, Ran, and Nishinari, Katsuyoshi

Subjects
QD, Q1
Abstract

Developing a facile method to prepare edible oleogels under moderate conditions would be of great interest. In this research, oleogels were obtained directly from the mixtures of cellulose particles (average particle size ≈ 25μm), sorbitan fatty acid esters (Span60 and Span40) and medium chain triglycerides (MCT). Results showed that 6% (w/w) cellulose particles combined with 9% (w/w) sorbitan fatty acid esters\ud could form a strong network to trap the oil phase through ultra-sonic treating. The strength of the oleogels could be regulated by the cellulose particles content and its ratio to surfactant. XRD, DSC and SEM data revealed that there was synergetic effect between the cellulose particles and fatty acid esters during the gelation. The cellulose particles covered with Span60 could associate with each other to form a network in the oil phase, in the similar way to the Span60 micelles. These findings would be significant for the development and application of food grade oleogels.

Published
2021

14. Determinants of survival in advanced non-small cell lung cancer patients treated with anti-PD-1/PD-L1 therapy

Author

Ali, Wael Abdullah Sultan, primary, Hui, Pan, additional, Ma, Yuxiang, additional, Wu, Yuehan, additional, Zhang, Yang, additional, Chen, Yukun, additional, Hong, Shaodong, additional, Yang, Yunpeng, additional, Huang, Yan, additional, Zhao, Yuanyuan, additional, Fang, Wenfeng, additional, Zhao, Hongyun, additional, and Zhang, Li, additional

Published
2021
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17. Representing Fertility in Mo Yan’s Frog and Xue Xiaolu’s Finding Mr. Right

Author

Wu, Yuehan

Subjects
China, Birth Tourism, One-Child Policy, Mo Yan, Fertility Politics, Rom-Com Film
Abstract

In this study I explore the changing representation of the pregnant body in two recent Chinese texts. Building on existing scholarship, I relate the fictional representation of maternity in Mo Yan’s novel "Frog" (2009) and Xue Xiaolu’s film "Finding Mr Right" (2013) to three consolidating discourses of reform, namely the Chinese family planning program, Chinese feminism, and Chinese globalization. By interrogating the highly symbolic depictions of pregnant women in these texts I meaningfully expand our understanding of the impact of these discourses through various scales and dimensionalities, including the generic, the social and the global. Approaching my topic in an interdisciplinary way, I disturb dualistic arguments that locate women in opposition to the political and reinstate everyday life as an arena of female agency as well as oppression. The introduction consists of a brief history of the implementation of the one-child policy in PRC and an analysis of the allegorical function of pregnancy and childbirth in Seventeen Year films. The main body of the thesis comprises close readings of two fictional texts that take pregnancy and gendered fertility politics as their theme. Written by the first Chinese writer to be awarded the Nobel Prize for Literature, "Frog" (translated into English in 2015) tells the story of a female obstetrician charged with implementing the one-child policy. Told from the perspective of an unreliable male narrator, the novel deploys techniques of satire and the grotesque. The story arcs across a 60-year history of birth control and mandatory abortion to end in the era of corporate baby farms. The second text is the Hollywood-style comedy "Finding Mr. Right" (2013), which concerns the idle and vain mistress of a mainland tycoon who enters the US to secure American citizenship for the baby she is carrying. The film’s focus on Chinese birth tourism works in tandem with its representation of the mother-to-be as a transnational female consumer who has yet to learn the value of love or money. I consider how the film links transnational practices with neoliberal ideology via a sentimental story in which heterosexual romance is suppressed in favour of female independence and entrepreneurship. I suggest that the medium of comedy allows the film’s writer and director to approach the feminist issues of female sexual citizenship and Chinese fertility politics through the sanctioned lens of maternity, a theme central to Chinese cinema since the Seventeen Year films discussed in the introduction. By comparing "Frog" and "Finding Mr Right", I am able to address the complex history and legacy of China’s one-child policy at the moment of its repeal.

Published
2016

19. Endonuclease EEPD1 Is a Gatekeeper for Repair of Stressed Replication Forks

Author

Kim, Hyun-Suk, primary, Nickoloff, Jac A., additional, Wu, Yuehan, additional, Williamson, Elizabeth A., additional, Sidhu, Gurjit Singh, additional, Reinert, Brian L., additional, Jaiswal, Aruna S., additional, Srinivasan, Gayathri, additional, Patel, Bhavita, additional, Kong, Kimi, additional, Burma, Sandeep, additional, Lee, Suk-Hee, additional, and Hromas, Robert A., additional

Published
2017
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22. EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair

Author

Wu, Yuehan, primary, Lee, Suk-Hee, additional, Williamson, Elizabeth A., additional, Reinert, Brian L., additional, Cho, Ju Hwan, additional, Xia, Fen, additional, Jaiswal, Aruna Shanker, additional, Srinivasan, Gayathri, additional, Patel, Bhavita, additional, Brantley, Alexis, additional, Zhou, Daohong, additional, Shao, Lijian, additional, Pathak, Rupak, additional, Hauer-Jensen, Martin, additional, Singh, Sudha, additional, Kong, Kimi, additional, Wu, Xaiohua, additional, Kim, Hyun-Suk, additional, Beissbarth, Timothy, additional, Gaedcke, Jochen, additional, Burma, Sandeep, additional, Nickoloff, Jac A., additional, and Hromas, Robert A., additional

Published
2015
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