Search

Your search keyword '"Wolf, Amaya I."' showing total 10 results
Start Over Author "Wolf, Amaya I." Search Limiters Full Text
10 results on '"Wolf, Amaya I."'

2. Design of amidobenzimidazole STING receptor agonists with systemic activity

Author

Ramanjulu, Joshi M., Pesiridis, G. Scott, Yang, Jingsong, Concha, Nestor, Singhaus, Robert, Zhang, Shu-Yun, Tran, Jean-Luc, Moore, Patrick, Lehmann, Stephanie, Eberl, H. Christian, Muelbaier, Marcel, Schneck, Jessica L., Clemens, Jim, Adam, Michael, Mehlmann, John, Romano, Joseph, Morales, Angel, Kang, James, Leister, Lara, Graybill, Todd L., Charnley, Adam K., Ye, Guosen, Nevins, Neysa, Behnia, Kamelia, Wolf, Amaya I., Kasparcova, Viera, Nurse, Kelvin, Wang, Liping, Puhl, Ana C., Li, Yue, Klein, Michael, Hopson, Christopher B., Guss, Jeffrey, Bantscheff, Marcus, Bergamini, Giovanna, Reilly, Michael A., Lian, Yiqian, Duffy, Kevin J., Adams, Jerry, Foley, Kevin P., Gough, Peter J., Marquis, Robert W., Smothers, James, Hoos, Axel, and Bertin, John

Published
2018
Full Text
View/download PDF

3. Author Correction: Design of amidobenzimidazole STING receptor agonists with systemic activity

Author

Ramanjulu, Joshi M., Pesiridis, G. Scott, Yang, Jingsong, Concha, Nestor, Singhaus, Robert, Zhang, Shu-Yun, Tran, Jean-Luc, Moore, Patrick, Lehmann, Stephanie, Eberl, H. Christian, Muelbaier, Marcel, Schneck, Jessica L., Clemens, Jim, Adam, Michael, Mehlmann, John, Romano, Joseph, Morales, Angel, Kang, James, Leister, Lara, Graybill, Todd L., Charnley, Adam K., Ye, Guosen, Nevins, Neysa, Behnia, Kamelia, Wolf, Amaya I., Kasparcova, Viera, Nurse, Kelvin, Wang, Liping, Puhl, Ana C., Li, Yue, Klein, Michael, Hopson, Christopher B., Guss, Jeffrey, Bantscheff, Marcus, Bergamini, Giovanna, Reilly, Michael A., Lian, Yiqian, Duffy, Kevin J., Adams, Jerry, Foley, Kevin P., Gough, Peter J., Marquis, Robert W., Smothers, James, Hoos, Axel, and Bertin, John

Published
2019
Full Text
View/download PDF

4. Protective antiviral antibody responses in a mouse model of influenza virus infection require TACI

Author

Wolf, Amaya I., Mozdzanowska, Krystyna, Quinn, III, William J., Metzgar, Michele, Williams, Katie L., Caton, Andrew J., Meffre, Eric, Bram, Richard J., Erickson, Loren D., Allman, David, Cancro, Michael P., and Erikson, Jan

Subjects
Cytokines -- Physiological aspects -- Research, Viral antibodies -- Physiological aspects -- Research, Influenza -- Development and progression -- Research, Antibodies -- Physiological aspects -- Research, Health care industry
Abstract

Antiviral Abs, for example those produced in response to influenza virus infection, are critical for virus neutralization and defense against secondary infection. While the half-life of Abs is short, Ab titers can last a lifetime due to a subset of the Ab-secreting cells (ASCs) that is long lived. However, the mechanisms governing ASC longevity are poorly understood. Here, we have identified a critical role for extrinsic cytokine signals in the survival of respiratory tract ASCs in a mouse model of influenza infection. Irradiation of mice at various time points after influenza virus infection markedly diminished numbers of lung ASCs, suggesting that they are short-lived and require extrinsic factors in order to persist. Neutralization of the TNF superfamily cytokines B lymphocyte stimulator (BLyS; also known as BAFF) and a proliferation-inducing ligand (APRIL) reduced numbers of antiviral ASCs in the lungs and bone marrow, whereas ASCs in the spleen and lung-draining lymph node were surprisingly unaffected. Mice deficient in transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI), a receptor for BLyS and APRIL, mounted an initial antiviral B cell response similar to that generated in WT mice but failed to sustain protective Ab titers in the airways and serum, leading to increased susceptibility to secondary viral challenge. These studies highlight the importance of TACI signaling for the maintenance of ASCs and protection against influenza virus infection., Introdution Antiviral Abs are critical for host protection and are the basis of successful vaccines. Abs produced in response to influenza infection are crucial for viral neutralization (1) and defense [...]

Published
2011
Full Text
View/download PDF

5. T Regulatory Cells Support Plasma Cell Populations in the Bone Marrow

Author

Glatman Zaretsky, Arielle, primary, Konradt, Christoph, additional, Dépis, Fabien, additional, Wing, James B., additional, Goenka, Radhika, additional, Atria, Daniela Gomez, additional, Silver, Jonathan S., additional, Cho, Sunglim, additional, Wolf, Amaya I., additional, Quinn, William J., additional, Engiles, Julie B., additional, Brown, Dorothy C., additional, Beiting, Daniel, additional, Erikson, Jan, additional, Allman, David, additional, Cancro, Michael P., additional, Sakaguchi, Shimon, additional, Lu, Li-Fan, additional, Benoist, Christophe O., additional, and Hunter, Christopher A., additional

Published
2017
Full Text
View/download PDF

7. Pneumolysin expression by streptococcus pneumoniae protects colonized mice from influenza virus-induced disease

Author

Wolf, Amaya I., primary, Strauman, Maura C., additional, Mozdzanowska, Krystyna, additional, Williams, Katie L., additional, Osborne, Lisa C., additional, Shen, Hao, additional, Liu, Qin, additional, Garlick, David, additional, Artis, David, additional, Hensley, Scott E., additional, Caton, Andrew J., additional, Weiser, Jeffrey N., additional, and Erikson, Jan, additional

Published
2014
Full Text
View/download PDF

9. Cooperativity Between CD8+ T Cells, Non-Neutralizing Antibodies, and Alveolar Macrophages Is Important for Heterosubtypic Influenza Virus Immunity

Author

Laidlaw, Brian J., primary, Decman, Vilma, additional, Ali, Mohammed-Alkhatim A., additional, Abt, Michael C., additional, Wolf, Amaya I., additional, Monticelli, Laurel A., additional, Mozdzanowska, Krystyna, additional, Angelosanto, Jill M., additional, Artis, David, additional, Erikson, Jan, additional, and Wherry, E. John, additional

Published
2013
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results