48 results on '"Wheatley, Mark"'
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2. Structural analysis of a nanoparticle containing a lipid bilayer used for detergent-free extraction of membrane proteins
3. Doxorubicin-induced cardiotoxicity: Investigating the effect on miRNA expression and G-protein coupled receptors mediated vascular tone
4. A novel thromboxane A2 receptor D304N variant that abrogates ligand binding in a patient with a bleeding diathesis
5. Differences in SMA-like polymer architecture dictate the conformational changes exhibited by the membrane protein rhodopsin encapsulated in lipid nano-particles
6. Single molecule binding of a ligand to a G-protein-coupled receptor in real time using fluorescence correlation spectroscopy, rendered possible by nano-encapsulation in styrene maleic acid lipid particles
7. Ligand-induced conformational changes in a SMALP-encapsulated GPCR.
8. Ligand-induced conformational changes in a SMALP-encapsulated GPCR.
9. Targeting V1A-vasopressin receptors with [Arg6, D-Trp7,9, NmePhe8]-substance P (6-11) identifies a strategy to develop novel anti-cancer therapies
10. Interactions Between RAMP2 And CRF Receptors:The Effect Of Receptor Subtypes, Splice Variants And Cell Context
11. The N-Terminal Juxtamembrane Segment of the V1a Vasopressin Receptor Provides Two Independent Epitopes Required for High-Affinity Agonist Binding and Signaling
12. An arginyl in the N-terminus of the V1a vasopressin receptor is part of the conformational switch controlling activation by agonist
13. A Single Residue (Arg46) Located Within the N-Terminus of the V1a Vasopressin Receptor Is Critical for Binding Vasopressin But Not Peptide or Nonpeptide Antagonists
14. Interactions between RAMP2 and CRF receptors: The effect of receptor subtypes, splice variants and cell context
15. Renal bradykinin and vasopressin receptors: Ligand selectivity and classification
16. An acid-compatible co-polymer for the solubilization of membranes and proteins into lipid bilayer-containing nanoparticles
17. A broad introduction to the design and construction of biosafety laboratories in low-resource settings : enhancement of CBRN capacities of South East Asia in addressing CBRN risk mitigation concerning CBRN first response, biosafety and biosecurity, awareness raising and legal framework
18. GPCR-styrene maleic acid lipid particles (GPCR-SMALPs):their nature and potential
19. G-protein coupled receptor solubilization and purification for biophysical analysis and functional studies, in the total absence of detergent
20. Offload zones to mitigate emergency medical services (EMS) offload delay in the emergency department: a process map and hazard analysis
21. Systematic analysis of the entire second extracellular loop of the V 1a vasopressin receptor :Key residues, conserved throughout a G-protein-coupled receptor family, identified
22. The second intracellular loop of the calcitonin gene-related peptide receptor provides molecular determinants for signal transduction and cell surface expression
23. Structural analysis of a nanoparticle containing a lipid bilayer used for detergent-free extraction of membrane proteins
24. Novel strategies for the design of receptor-selective vasopressin analogues: Aib-substitution and retro-inverso transformation
25. Charged extracellular residues, conserved throughout a G-protein-coupled receptor family, are required for ligand binding, receptor activation, and cell-surface expression
26. Systematic Analysis of the Entire Second Extracellular Loop of the V1a Vasopressin Receptor
27. Charged Extracellular Residues, Conserved throughout a G-protein-coupled Receptor Family, Are Required for Ligand Binding, Receptor Activation, and Cell-surface Expression
28. Characterization of the Structure of RAMP1 by Mutagenesis and Molecular Modeling
29. The Second Intracellular Loop of the Calcitonin Gene-related Peptide Receptor Provides Molecular Determinants for Signal Transduction and Cell Surface Expression
30. A Gly/Ala switch contributes to high affinity binding of benzoxazinone-based non-peptide oxytocin receptor antagonists
31. The expression, activity and localisation of the secretory pathway Ca2+-ATPase (SPCA1) in different mammalian tissues
32. Neuropeptides, Amines and Amino Acids as Mediators of the Sympathetic Effects of Paraventricular Nucleus Activation in the Rat
33. A Single Residue (Arg46) Located Within the N-Terminus of the V1aVasopressin Receptor Is Critical for Binding Vasopressin But Not Peptide or Nonpeptide Antagonists
34. Palmitoylation of the Vasopressin V1a Receptor Reveals Different Conformational Requirements for Signaling, Agonist-induced Receptor Phosphorylation, and Sequestration
35. Identification of the glycosylation sites utilized on the V1a vasopressin receptor and assessment of their role in receptor signalling and expression
36. Identification of an extracellular segment of the oxytocin receptor providing agonist-specific binding epitopes
37. Novel strategies for the design of receptor-selective vasopressin analogues: Aib-substitution and retro-inverso transformation
38. Molecular recognition of peptide and non-peptide ligands by the extracellular domains of neurohypophysial hormone receptors
39. Fluorescent and biotinylated linear peptides as selective bifunctional ligands for the V1a vasopressin receptor
40. A Gly/Ala switch contributes to high affinity binding of benzoxazinone-based non-peptide oxytocin receptor antagonists
41. An arginyl in the N-terminus of the V1a vasopressin receptor is part of the conformational switch controlling activation by agonist.
42. Palmitoylation of the Vasopressin V1aReceptor Reveals Different Conformational Requirements for Signaling, Agonist-induced Receptor Phosphorylation, and Sequestration*
43. Characterisation of brain D 2dopamine receptors solubilised by lysophosphatidylcholine
44. Characterisation of brain D2dopamine receptors solubilised by lysophosphatidylcholine
45. Characterisation of brain D2 dopamine receptors solubilised by lysophosphatidylcholine
46. Characterisation of brain D 2 dopamine receptors solubilised by lysophosphatidylcholine
47. The expression, activity and localisation of the secretory pathway Ca2+-ATPase (SPCA1) in different mammalian tissues
48. Systematic Analysis of the Entire Second Extracellular Loop of the V1a Vasopressin Receptor.
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