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Visible Light Communication (VLC) has become an effective underwater communication technology due to its advantages such as fast transmission speed and strong confidentiality. When light propagates underwater, it is prone to scattering, resulting in a decrease in the energy of light propagation with the increase of transmission distance. Therefore, improving the responsiveness of the receiving end is the key technology to achieve underwater VLC. This article first designs a new holographic waveguide focusing system for the front end of the detector, which can effectively improve the signal-to-noise ratio of underwater detectors. Then, we construct a low-cost antimony sulfide thin film detector with weak light detection capability. Based on the built VLC system, the experimental results show that the dark current of the receiver detector is only 10-7 A/cm2, with a 3 dB bandwidth of 220 kHz, a response of 0.2 A/W, and an external quantum efficiency of over 70% in the blue green light band. Therefore, the new antimony sulfide thin film detector combined with a holographic waveguide focusing system can achieve weak light detection of visible light, making it a very effective underwater visible light receiving system.

Background With the aggravation of aging trend, the influence of intergenerational support on the health of the elderly has gradually attracted attention, and the absence of spiritual care and life care is an important factor for the occurrence of health problems in the elderly, but there is a lack of scientific evaluation tools to evaluate the cognitive level of old-age care. Objective To develop a Knowledge, Attitude and Practice about Filial Piety Ethics Questionnaires for Offspring and Grandchildren in the process of elderly care, and to test its reliability and validity. Methods From April to July 2021, the first draft of the questionnaire was determined by searching relevant contents in databases such as PubMed, Web of Science, China Knowledge Network and Wanfang Data Knowledge Service Platform, and using the theory of knowledge, attitude and practice and Maslow's hierarchy of needs as the theoretical framework, combined with literature review, national maintenance laws, qualitative interviews, the questionnaire was refined with results of the Delphi expert consensus and pre-survey. From October 2021 to March 2022, 270 subjects from each generation were selected for the formal survey and 50 subjects from the offspring and 38 subjects from the grangchildren were selected for test-retest reliability using the random cluster sampling method. A total of 540 questionnaires were distributed, 270 questionnaires for each generation. A total of 528 valid questionnaires were returned, 264 valid questionnaires for each generation, with a valid return rate of 97.8%. Its reliability and validity were analyzed to determine the final questionnaire entry. Results The Knowledge, Attitude and Practice about Filial Piety Ethics Questionnaires for Offsprings included 3 dimensions and 34 items. Exploratory factor analysis produced 3 factors, with a cumulative variance contribution rate of 64.455%. The content validity of each item ranged from 0.867 to 1.000, and the average content validity of the questionnaire was 0.967. Cronbach's α coefficient was 0.953, split-half reliability was 0.811, and test-retest reliability was 0.987. The Knowledge, Attitude and Practice about Filial Piety Ethics Questionnaires for Grandchildren consisted of 31 items in 3 dimensions. Exploratory factor analysis produced three factors, the cumulative variance contribution rate was 64.641%; the content validity of each item ranged from 0.867 to 1.000, the average content validity of the questionnaire was 0.964; Cronbach's α coefficient was 0.952, split-half reliability was 0.837, and test-retest reliability was 0.991. Conclusion The developed questionnaire has good reliability and validity, and can be used as a research tool to evaluate the current status of filial piety ethic knowledge, attitude and behavior of offsprings and grandchildren in the process of elderly care.

Byline: Yu-Hao. Wang, Pi-Hsiung. Wu, Hsing-Hao. Su, Chung-Yang. Wang, Lan. Hsu Background: Much attention has been focused on environmental risk factors and their roles in eczema development. In this regard, [...]

In view of problems existed in current running state monitoring and over-speed protection device of endless-rope continuous towing vehicle, the paper proposed a design scheme of running state monitoring and over-speed protection system of endless-rope continuous towing vehicle. The system uses structure of upper-lower computer. The upper computer based on LabVIEW realizes functions of parameter setting, data storage, running state display and remote control. The lower computer firstly collects signals of running speed and pressure of accumulator of braking system and brake oil-cylinder, then analyzes, processes and judges the signals with some algorithm by use of single-chip microcomputer. The lower computer can output corresponding fault signal if the vehicle has faults of over-speed, under voltage and broken rope. The upper computer communicates with the lower computer with wireless mode. The actual application showed that the system can realize effective monitoring for running state and correct judgment for over-speed fault of the vehicle.

Background: Docetaxel (DTX) exhibits antitumor effects against breast cancer by stabilizing microtubules and increasing the accumulation of reactive oxygen species (ROS). DTX extravasation during infusion often causes skin injury. The present study aimed to investigate the effects and mechanisms of icaritin (ICT) on DTX‐induced skin injury. Methods: The effects of ICT on the viability and apoptosis of HaCaT cells were measured by SRB assay and flow cytometry, respectively. Endogenous LC3 puncta and microtubules were determined by immunofluorescence. The number of mitochondria was measured by MitoTracker orange staining. ROS were determined by dihydroethidium staining. The expression of markers of ROS and autophagy were measured by western blotting. Chloroquine, compound D, and tamoxifen were employed as the inhibitor for autophagy and AMPK, estrogen receptors (ERs) modulator, respectively. Results: DTX inhibited the viability and decreased apoptosis of HaCaT cells, which can be rescued by ICT. ICT decreased microtubule bundles, increased the number of mitochondria, and attenuated ROS of HaCaT cells induced by DTX. ICT blocks autophagy and the autophagic flux. Compound C or tamoxifen diminished the protection effects of ICT on DTX‐treated HaCaT cells. Conclusion: ICT alleviates DTX‐induced skin injury by suppressing ROS, reducing microtubule bundles, and blocking autophagy via ERs. Our study indicated that ICT may be a potential candidate for DTX‐induced skin injury. [ABSTRACT FROM AUTHOR]